| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abhishek Sharma, Narayana Reddy Pedavenkatagari, Bhujanga Rao Nagulancha, Narasimha Swamy Lakk. Separation and Quantitative Estimation of Pharmacopeial Organic Impurities, Process-Related Impurities, and Degradation Products of the Anti-Schizophrenia Drug Clozapine in Pharmaceutical Formulations by Using Stability-Indicating HPLC Method. Biomedical chromatography : BMC. vol 39. issue 3. 2025-02-10. PMID:39930323. |
clozapine is an antipsychotic medication primarily used to treat severe schizophrenia symptoms. |
2025-02-10 |
2025-02-13 |
Not clear |
| Xiaobo Xie, Jinzhang Chen, Hongli Song, Zebin Fa. Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report. Frontiers in psychiatry. vol 15. 2025-02-04. PMID:39902243. |
clozapine and chlorpromazine are widely used for treating schizophrenia. |
2025-02-04 |
2025-02-06 |
Not clear |
| André Luiz Schuh Teixeira da Rosa, Marina Ribeiro Barreto da Costa, Gabriela Bezerra Sorato, Felipe de Moura Manjabosco, Érica Bonganhi de Bem, Lucas Dellazari, Arthur Bezerra Falcão, Lucas de Oliveira Cia, Olivia Sorato Bezerra, Rogério Boff Borges, Luis Augusto Rohde, Ana Soledade Graeff-Martin. Clozapine for Treatment-Resistant Disruptive Behaviors in Youths With Autism Spectrum Disorder Aged 10-17 Years: Protocol for an Open-Label Trial. JMIR research protocols. vol 14. 2025-01-30. PMID:39883920. |
clozapine, noted for its unique antiaggressive effects in schizophrenia and in various treatment-resistant neuropsychiatric disorders, independent from its antipsychotic efficacy, remains underexplored in youths with asd facing severe and persistent db. |
2025-01-30 |
2025-02-02 |
Not clear |
| Sandeep Grover, Nidhi Yada. Misidentification syndromes: A retrospective study from India. Asian journal of psychiatry. vol 104. 2025-01-29. PMID:39879881. |
the study found that 12 out of 16 patients with schizophrenia or schizoaffective disorder with dms had treatment-resistance, necessitating the use of clozapine, with 4 patients also requiring electroconvulsive therapy. |
2025-01-29 |
2025-02-01 |
Not clear |
| Evelyn Moreno Tarazona, Mauricio Orozco Gonzalez, Andrea La Rosa Giron, Paulo Ruiz-Grosso, Maria Lazo-Porra. Prevalence of obsessive-compulsive symptoms in patients with schizophrenia treated with clozapine: a scoping review. BMC psychiatry. vol 25. issue 1. 2025-01-24. PMID:39849391. |
prevalence of obsessive-compulsive symptoms in patients with schizophrenia treated with clozapine: a scoping review. |
2025-01-24 |
2025-01-26 |
Not clear |
| Evelyn Moreno Tarazona, Mauricio Orozco Gonzalez, Andrea La Rosa Giron, Paulo Ruiz-Grosso, Maria Lazo-Porra. Prevalence of obsessive-compulsive symptoms in patients with schizophrenia treated with clozapine: a scoping review. BMC psychiatry. vol 25. issue 1. 2025-01-24. PMID:39849391. |
schizophrenia is a complex psychiatric disorder, and in patients treated with clozapine, it may induce or exacerbate obsessive-compulsive symptoms (ocs), which negatively affect patients' quality of life, functionality and treatment adherence. |
2025-01-24 |
2025-01-26 |
Not clear |
| Anna Mach, Anna Wnorowska, Marcin Siwek, Marcin Wojnar, Maria Radziwoń-Zalesk. The effects of clinical and pharmacological factors on the ratio of clozapine to norclozapine in psychiatric patients. Frontiers in pharmacology. vol 15. 2025-01-22. PMID:39840091. |
due to its exceptional effectiveness, clozapine (clo), whose metabolite is norclozapine (nclo), is a drug of choice in the management of treatment-resistant schizophrenia. |
2025-01-22 |
2025-01-24 |
Not clear |
| Nicolette Centanni, Kayla Garvey, Elizabeth Mullany, Stephanie Nichol. Cross-titration from risperidone to clozapine utilizing clozapine serum concentrations: A case report. Pharmacotherapy. 2025-01-21. PMID:39835595. |
clozapine and risperidone are second-generation antipsychotics used in the treatment of schizophrenia. |
2025-01-21 |
2025-01-23 |
Not clear |
| Kaoru Matsuo-Yamamoto, Shinya Uenishi, Yuta Ishiyama, Shinichi Yamada, Yuji Kitabata, Kazuya Okamura, Sohei Kimot. Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report. Neuropsychopharmacology reports. vol 45. issue 1. 2025-01-21. PMID:39835733. |
successful clozapine treatment for treatment-resistant schizophrenia with zinc deficiency severe anemia: a case report. |
2025-01-21 |
2025-01-23 |
Not clear |
| Kaoru Matsuo-Yamamoto, Shinya Uenishi, Yuta Ishiyama, Shinichi Yamada, Yuji Kitabata, Kazuya Okamura, Sohei Kimot. Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report. Neuropsychopharmacology reports. vol 45. issue 1. 2025-01-21. PMID:39835733. |
clozapine is an atypical antipsychotic drug approved for treatment-resistant schizophrenia (trs). |
2025-01-21 |
2025-01-23 |
Not clear |
| Robert James Flanagan, Stephen John Obee, Alice Hyun Min Kim, Susanna Every-Palme. Effect of Valproate Coprescription on Clozapine Pharmacokinetics in Clinical Practice. Journal of clinical psychopharmacology. vol 44. issue 6. 2025-01-21. PMID:39836512. |
sodium valproate has been coprescribed with clozapine for seizure prophylaxis and for augmentation in treatment-refractory schizophrenia. |
2025-01-21 |
2025-01-24 |
Not clear |
| Kiran Basawaraj Bagali, Harsh Pathak, Swarna Buddha Nayok, Srinivas Balachander, Vanteemar S Sreeraj, Ganesan Venkatasubramania. Lateral Occipital Cortex as a Novel Target for Neuromodulation to Attenuate Auditory and Visual Hallucinations in a Patient with Ultra-treatment-resistant Schizophrenia: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 23. issue 1. 2025-01-17. PMID:39820124. |
here we report of a case of a 29-year-old female diagnosed with treatment resistant schizophrenia on clozapine with persistent auditory verbal hallucinations (avh) and visual anomalies. |
2025-01-17 |
2025-01-20 |
Not clear |
| Mete Ercis, Kristin C Cole, Ross A Dierkhising, Aysegul Ozerdem, Matej Markota, Balwinder Singh, Susan L McElroy, Mark A Frye, Jonathan G Leun. Clinical and Demographic Predictors of Early Clozapine Discontinuation Across Mood and Psychotic Disorders. Journal of clinical psychopharmacology. 2025-01-13. PMID:39804782. |
clozapine is effective for treatment-resistant schizophrenia and bipolar disorder but is often discontinued due to adverse effects. |
2025-01-13 |
2025-01-16 |
Not clear |
| Robert James Flanagan, Stephen John Obee, Alice Hyun Min Kim, Susanna Every-Palme. Clozapine Dosage in Treatment-Refractory Schizophrenia: A Reply to Dr Grover and Colleagues. Journal of clinical psychopharmacology. 2025-01-13. PMID:39804779. |
clozapine dosage in treatment-refractory schizophrenia: a reply to dr grover and colleagues. |
2025-01-13 |
2025-01-16 |
Not clear |
| Fezile Ozdemir, Merve Demirbugen Oz, Kenan Can Tok, Emrah Dural, Yagmur Kır, Mehmet Gumustas, Bora Baskak, H Sinan Suze. The effects of UGT1A4 and ABCB1 polymorphisms on clozapine and N- desmethyl clozapine plasma levels in Turkish schizophrenia patients. Toxicology and applied pharmacology. vol 495. 2025-01-09. PMID:39761923. |
the effects of ugt1a4 and abcb1 polymorphisms on clozapine and n- desmethyl clozapine plasma levels in turkish schizophrenia patients. |
2025-01-09 |
2025-01-13 |
Not clear |
| Fezile Ozdemir, Merve Demirbugen Oz, Kenan Can Tok, Emrah Dural, Yagmur Kır, Mehmet Gumustas, Bora Baskak, H Sinan Suze. The effects of UGT1A4 and ABCB1 polymorphisms on clozapine and N- desmethyl clozapine plasma levels in Turkish schizophrenia patients. Toxicology and applied pharmacology. vol 495. 2025-01-09. PMID:39761923. |
clozapine (clz) is an antipsychotic which is particularly used in treatment resistant schizophrenia patients who do not respond to other agents. |
2025-01-09 |
2025-01-13 |
Not clear |
| Fezile Ozdemir, Merve Demirbugen Oz, Kenan Can Tok, Emrah Dural, Yagmur Kır, Mehmet Gumustas, Bora Baskak, H Sinan Suze. The effects of UGT1A4 and ABCB1 polymorphisms on clozapine and N- desmethyl clozapine plasma levels in Turkish schizophrenia patients. Toxicology and applied pharmacology. vol 495. 2025-01-09. PMID:39761923. |
the aim of the study is to evaluate the effects of abcb1 rs1045642 and ugt1a4 rs2011425 polymorphisms on clz and its major metabolite n- desmethly clozapine (dclz) plasma concentrations in patients with schizophrenia. |
2025-01-09 |
2025-01-13 |
Not clear |
| Abdul Qadir, Syed Umer Jan, Muhammad Harris Shoaib, Muhammad Sikandar, Rabia Ismail Yousuf, Fatima Ramzan Ali, Fahad Siddiqui, Abdul Jabbar Magsi, Ghulam Mustafa, Muhammad Talha Saleem, Shafi Mohammad, Mohammad Younis, Muhammad Arsala. Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches. Scientific reports. vol 15. issue 1. 2025-01-08. PMID:39774012. |
clozapine is a potent serotonin receptor antagonist and commonly used for the treatment of schizophrenia. |
2025-01-08 |
2025-01-13 |
Not clear |
| Shanathan Sritharan, Kindelan Murray, Dominic Lam, Daniel Wittaker, Aaron Sverdlov, Andrew Boyle, Allan Davies, Trent Williams, Nicholas Collin. A retrospective analysis of cardiovascular outcomes of clozapine treated individuals within Hunter New England. Internal medicine journal. 2025-01-08. PMID:39776141. |
clozapine has demonstrated superiority in improving both positive and negative symptoms of treatment-resistant schizophrenia; however, there are associated treatment-limiting side effects, including myocarditis, cardiomyopathy and agranulocytosis. |
2025-01-08 |
2025-01-13 |
Not clear |
| Ying Zhang, Ranli Li, Ximing Chen, Yachen Li, Qiuyu Zhang, Lei Yang, Lina Wang, Yun Sun, Fuqiang Mao, Chuan Jun Zhu. Clozapine Induces Agranulocytosis via Inflammatory and Hematopoietic Cytokine Induction of the JAK-STAT Signaling Pathway: Evidence From Network Pharmacology and Molecular Docking. CNS neuroscience & therapeutics. vol 31. issue 1. 2025-01-08. PMID:39776289. |
clozapine exhibits significant therapeutic efficacy in schizophrenia, especially treatment-resistant schizophrenia. |
2025-01-08 |
2025-01-13 |
Not clear |