| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaoru Noda, Takehiro Kato, Nao Nomura, Mayu Sakai, Sodai Kubota, Tokuyuki Hirose, Yanyan Liu, Yoshihiro Takahashi, Ken Takao, Masami Mizuno, Takuo Hirota, Tetsuya Suwa, Yukio Horikawa, Daisuke Yab. Semaglutide is effective in type 2 diabetes and obesity with schizophrenia. Diabetology international. vol 13. issue 4. 2022-09-19. PMID:36117924. |
prevention and treatment of type 2 diabetes and obesity are problematic for individuals with schizophrenia partly because atypical antipsychotics and mental distress themselves increase appetite, thus promoting subsequent body weight gain and deterioration of glycemic control. |
2022-09-19 |
2023-08-14 |
Not clear |
| Aditi Kadakia, Brenna L Brady, Carole Dembek, G Rhys Williams, Justine M Ken. Burden of EPS in commercial patients with schizophrenia initiating atypical antipsychotics. The American journal of managed care. vol 28. issue 9. 2022-09-19. PMID:36121363. |
burden of eps in commercial patients with schizophrenia initiating atypical antipsychotics. |
2022-09-19 |
2023-08-14 |
Not clear |
| Aditi Kadakia, Brenna L Brady, Carole Dembek, G Rhys Williams, Justine M Ken. Burden of EPS in commercial patients with schizophrenia initiating atypical antipsychotics. The American journal of managed care. vol 28. issue 9. 2022-09-19. PMID:36121363. |
this study examined the incidence and economic burden of eps in patients with schizophrenia initiating atypical antipsychotics (aaps). |
2022-09-19 |
2023-08-14 |
Not clear |
| Carlos Fernández-Pereira, Maria Aránzazu Penedo, Tania Rivera-Baltanas, Rafael Fernández-Martínez, Saida Ortolano, José Manuel Olivares, Roberto Carlos Agís-Balbo. Insulin-like Growth Factor 2 (IGF-2) and Insulin-like Growth Factor Binding Protein 7 (IGFBP-7) Are Upregulated after Atypical Antipsychotics in Spanish Schizophrenia Patients. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36076984. |
insulin-like growth factor 2 (igf-2) and insulin-like growth factor binding protein 7 (igfbp-7) are upregulated after atypical antipsychotics in spanish schizophrenia patients. |
2022-09-09 |
2023-08-14 |
Not clear |
| Fiammetta Iannuzzo, Gianpaolo Antonio Basile, Domenica Campolo, Giovanni Genovese, Gianluca Pandolfo, Loretta Giunta, Domenica Ruggeri, Antonino Di Benedetto, Antonio Brun. Metabolic and clinical effect of alpha-lipoic acid administration in schizophrenic subjects stabilized with atypical antipsychotics: A 12-week, open-label, uncontrolled study. Current research in pharmacology and drug discovery. vol 3. 2022-08-22. PMID:35992380. |
alpha-lipoic acid (ala) was proposed as a new approach in schizophrenia to improve metabolic effects of atypical antipsychotics. |
2022-08-22 |
2023-08-14 |
human |
| Akitoyo Hishimoto, Norio Yasui-Furukori, Daisuke Sekine, Miyuki Matsukawa, Sakiko Yamad. Treatment Discontinuation Among Patients with Schizophrenia Treated with Brexpiprazole and Other Oral Atypical Antipsychotics in Japan: A Retrospective Observational Study. Advances in therapy. 2022-07-29. PMID:35904721. |
treatment discontinuation among patients with schizophrenia treated with brexpiprazole and other oral atypical antipsychotics in japan: a retrospective observational study. |
2022-07-29 |
2023-08-14 |
Not clear |
| Akitoyo Hishimoto, Norio Yasui-Furukori, Daisuke Sekine, Miyuki Matsukawa, Sakiko Yamad. Treatment Discontinuation Among Patients with Schizophrenia Treated with Brexpiprazole and Other Oral Atypical Antipsychotics in Japan: A Retrospective Observational Study. Advances in therapy. 2022-07-29. PMID:35904721. |
the aim of this exploratory study was to compare the time to treatment discontinuation between patients with schizophrenia prescribed brexpiprazole (brx group) and those prescribed other atypical antipsychotics (oaa group) in clinical settings in japan using health insurance claims data. |
2022-07-29 |
2023-08-14 |
Not clear |
| Hannah W Haddad, Elena Boardman, Brooke Williams, Rama Mouhaffel, Adam M Kaye, Alan D Kay. Combination Olanzapine and Samidorphan for the Management of Schizophrenia and Bipolar 1 Disorder in Adults: A Narrative Review. Health psychology research. vol 10. issue 3. 2022-07-01. PMID:35774916. |
to date, olanzapine is one of the most efficacious atypical antipsychotics (aaps) for the treatment of both schizophrenia and b1d and is associated with fewer extrapyramidal effects compared to other treatments. |
2022-07-01 |
2023-08-14 |
Not clear |
| Kouji Fukuyama, Eishi Motomura, Motohiro Okad. Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743014. |
recent pharmacodynamic studies suggested that tripartite synaptic transmission can contribute to the pathophysiology of schizophrenia and mood disorders, their associated cognitive impairment, and several adverse reactions to atypical antipsychotics. |
2022-06-24 |
2023-08-14 |
rat |
| Dandan Wang, Ning Wei, Fangzhen Hu, Jianhua Li, Yucheng Wang, Zhiwei Qian, Miao Yang, Mingrong Yao, Yong Xia, Hong Yu, Wenzhen Tu, Minjie Ye, Cheng Qian, Jianbo Hu, Jingkai Chen, Chanchan Hu, Manli Huang, Yi Xu, Shaohua H. Paliperidone Extended Release Versus Olanzapine in Treatment-Resistant Schizophrenia: A Randomized, Double-Blind, Multicenter Study. Journal of clinical psychopharmacology. 2022-06-13. PMID:35695720. |
paliperidone is an atypical antipsychotic as effective as other atypical antipsychotics for schizophrenia. |
2022-06-13 |
2023-08-14 |
Not clear |
| Ammara Saleem, Qurat-Ul-Ain, Muhammad Furqan Akhta. Alternative Therapy of Psychosis: Potential Phytochemicals and Drug Targets in the Management of Schizophrenia. Frontiers in pharmacology. vol 13. 2022-06-03. PMID:35656298. |
management of schizophrenia is usually carried out with typical and atypical antipsychotics, but it yields modest benefits with a diversity of side effects. |
2022-06-03 |
2023-08-14 |
Not clear |
| Jaedeok Kim, Nayoung Lee, Sang Bum Suh, Sooyeon Jang, Saeha Kim, Dong-Gyu Kim, Jong Kook Park, Keun-Wook Lee, Soo Young Choi, Chan Hee Le. Metformin ameliorates olanzapine-induced disturbances in POMC neuron number, axonal projection, and hypothalamic leptin resistance. BMB reports. 2022-06-02. PMID:35651327. |
while atypical antipsychotics such as aripiprazole are not associated with obesity and diabetes, olanzapine is still widely used based on the anticipation that it is more effective in treating severe schizophrenia than aripiprazole, despite its metabolic side effects. |
2022-06-02 |
2023-08-13 |
mouse |
| Magda Kondej, Tomasz M Wróbel, Katarzyna M Targowska-Duda, Antón Leandro Martínez, Oliwia Koszła, Piotr Stępnicki, Agata Zięba, Alba Paz, Olga Wronikowska-Denysiuk, Maria I Loza, Marián Castro, Agnieszka Anna Kaczo. Multi-target derivatives of D2AAK1 as potential antipsychotics - the effect of the substitution in the indole moiety. ChemMedChem. 2022-05-24. PMID:35610178. |
schizophrenia is a complex disease which is best treated with multi-target drugs, such as atypical antipsychotics. |
2022-05-24 |
2023-08-13 |
mouse |
| Aditi Kadakia, Brenna Brady, Carole Dembek, Rhys Williams, Justine Ken. The Incidence and Economic Burden of Extrapyramidal Symptoms in Patients with Schizophrenia Initiating Atypical Antipsychotics in a Commercially Insured Population. CNS spectrums. vol 27. issue 2. 2022-04-28. PMID:35477614. |
the incidence and economic burden of extrapyramidal symptoms in patients with schizophrenia initiating atypical antipsychotics in a commercially insured population. |
2022-04-28 |
2023-08-13 |
Not clear |
| M A Lech, K Kaminska, A Wasik, E Lorenc-Koci, Z Rogo. Repeated co-treatment with mirtazapine and aripiprazole reversed the schizophrenia-like behaviors and increased the brain-derived neurotrophic factor mRNA expression in the adult Sprague-Dawley rats exposed to glutathione deficit during early postnatal brain development. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 72. issue 5. 2022-02-14. PMID:35158332. |
moreover, some studies have suggested that antidepressants are able to increase the activity of atypical antipsychotics which may efficiently improve the treatment of negative and some cognitive symptoms of schizophrenia. |
2022-02-14 |
2023-08-13 |
rat |
| Yingchan Wang, Yuchao Jiang, Dengtang Liu, Jianye Zhang, Dezhong Yao, Cheng Luo, Jijun Wan. Atypical Antipsychotics Mediate Dynamics of Intrinsic Brain Activity in Early-Stage Schizophrenia? A Preliminary Study. Psychiatry investigation. vol 18. issue 12. 2021-12-30. PMID:34965706. |
atypical antipsychotics mediate dynamics of intrinsic brain activity in early-stage schizophrenia? |
2021-12-30 |
2023-08-13 |
Not clear |
| Yingchan Wang, Yuchao Jiang, Dengtang Liu, Jianye Zhang, Dezhong Yao, Cheng Luo, Jijun Wan. Atypical Antipsychotics Mediate Dynamics of Intrinsic Brain Activity in Early-Stage Schizophrenia? A Preliminary Study. Psychiatry investigation. vol 18. issue 12. 2021-12-30. PMID:34965706. |
abnormalities of static brain activity have been reported in schizophrenia, but it remains to be clarified the temporal variability of intrinsic brain activities in schizophrenia and how atypical antipsychotics affect it. |
2021-12-30 |
2023-08-13 |
Not clear |
| Luyao He, Yimin Yu, Lei Zhang, Shen He, Wenjuan Yu, Lujin Li, Jingjing Huang, Huafang L. A Real-World Study of Risk Factors for QTc Prolongation in Schizophrenia Patients Receiving Atypical Antipsychotics. Journal of clinical psychopharmacology. vol 42. issue 1. 2021-12-20. PMID:34928562. |
a real-world study of risk factors for qtc prolongation in schizophrenia patients receiving atypical antipsychotics. |
2021-12-20 |
2023-08-13 |
Not clear |
| Pan Yan, Bing Gao, Shuqi Wang, Shengdong Wang, Jing Li, Mingfen Son. Association of 5-HTR2A T102C and A-1438G polymorphisms with clinical response to atypical antipsychotic treatment in schizophrenia: a meta-analysis. Neuroscience letters. 2021-12-17. PMID:34919991. |
associations of serotonin 2a receptor (5-htr2a) gene polymorphisms with clinical response to atypical antipsychotics (aaps) treatment in schizophrenia (scz) were inconsistent. |
2021-12-17 |
2023-08-13 |
Not clear |
| Enrico Capuzzi, Alessandro Ceresa, Alice Caldiroli, Cecilia M Esposito, Paolo Ossola, Massimiliano Buol. The Relation between the Plasma Concentrations of Long-Acting Atypical Antipsychotics and Clinical Effectiveness in Patients Affected by Schizophrenia or Schizoaffective Disorder: A Comprehensive Overview. Current pharmaceutical design. vol 27. issue 39. 2021-12-07. PMID:34459376. |
the relation between the plasma concentrations of long-acting atypical antipsychotics and clinical effectiveness in patients affected by schizophrenia or schizoaffective disorder: a comprehensive overview. |
2021-12-07 |
2023-08-13 |
Not clear |