| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yaoyao Zhang, Wei Tang, Bei Tang, Kaili Fan, Ke Zhao, Xinyu Fang, Hui Li. Altered mitochondrial lymphocyte in overweight schizophrenia patients treated with atypical antipsychotics and its association with cognitive function. Frontiers in immunology. vol 14. 2024-01-18. PMID:38235140. |
altered mitochondrial lymphocyte in overweight schizophrenia patients treated with atypical antipsychotics and its association with cognitive function. |
2024-01-18 |
2024-01-20 |
Not clear |
| Kouji Fukuyama, Eishi Motomura, Motohiro Okad. A Novel Gliotransmitter, L-β-Aminoisobutyric Acid, Contributes to Pathophysiology of Clinical Efficacies and Adverse Reactions of Clozapine. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759688. |
considering the expressions of gaba-b and iii-mglu receptors (localised in the presynaptic regions), the activation of gaba-b and iii-mglu receptors can explain the distinct therapeutic advantages of clozapine in schizophrenia or trs associated with n-methyl-d-aspartate (nmda) receptor disturbance compared with other atypical antipsychotics via the inhibition of the persistent tonic hyperactivation of thalamocortical glutamatergic transmission in the prefrontal cortex. |
2023-09-28 |
2023-10-07 |
Not clear |
| Xinyu Fang, Chunying Gao, Weifeng Wu, Xiuxiu Hu, Miaomiao Shao, Chou Zhou, Renliang Cai, Jin Fang, Yi Li, Yue Xu, Xiangrong Zhan. The role of the gut microbiome in weight-gain in schizophrenia patients treated with atypical antipsychotics: Evidence based on altered composition and function in a cross-sectional study. Psychiatry research. vol 328. 2023-09-17. PMID:37717547. |
the role of the gut microbiome in weight-gain in schizophrenia patients treated with atypical antipsychotics: evidence based on altered composition and function in a cross-sectional study. |
2023-09-17 |
2023-10-07 |
Not clear |
| Soumitra Das, Annie Itrat, Mary Elizabeth Trejo Hernandez, Rasish Subedi, Thusanth Jogarajah, Sreshatha Vashist, Nikitha Daggal. Clozapine-induced eosinophilia: A case report. SAGE open medical case reports. vol 11. 2023-09-05. PMID:37667744. |
clozapine is one of the best atypical antipsychotics and is highly effective in treating treatment-resistant schizophrenia. |
2023-09-05 |
2023-09-07 |
Not clear |
| Hidekazu Sotoyam. Putative neural mechanisms underlying release-mode-specific abnormalities in dopamine neural activity in a schizophrenia-like model: The distinct roles of glutamate and serotonin in the impaired regulation of dopamine neurons. The European journal of neuroscience. 2023-08-23. PMID:37611917. |
these results provide an idea about the mechanism of dopamine disturbance in schizophrenia and may be informative in explaining the effects of atypical antipsychotics as distinct from those of typical drugs. |
2023-08-23 |
2023-09-07 |
Not clear |
| Yanlin Wang, Xiaofeng Wang, Frank Larsen, Dana Cahill, Argie Zoubroulis, Caroline Ward, Eva Kohegyi, Arash Raoufini. Population Pharmacokinetic Analysis of Brexpiprazole to Support its Indication and Dose Selection in Adolescents With Schizophrenia. Journal of clinical pharmacology. 2023-07-18. PMID:37461192. |
in order to accelerate pediatric drug development, the united states food and drug administration (fda) released a general advice letter to sponsors permitting the effectiveness of atypical antipsychotics for the treatment of schizophrenia in adults to be extrapolated to adolescents based on a pharmacokinetic (pk) analysis to support dose selection, plus a safety study. |
2023-07-18 |
2023-08-14 |
Not clear |
| Michal R Tomaszewski, Jun Meng, Hyking D Haley, Charles M Harrell, Terrence P Mcdonald, Corin O Miller, Sean M Smit. Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment. Journal of lipid research. 2023-07-02. PMID:37393952. |
weight gain is a common harmful side effect of atypical antipsychotics used for schizophrenia treatment. |
2023-07-02 |
2023-08-14 |
mouse |
| Avijeet S Chopra, Dusica Hadzi Boskovic, Amit Kulkarni, Jeffrey M Cochra. Cost-Effectiveness of Aripiprazole Tablets with Sensor versus Oral Atypical Antipsychotics for the Treatment of Schizophrenia Using a Patient-Level Microsimulation Modeling Approach. ClinicoEconomics and outcomes research : CEOR. vol 15. 2023-05-30. PMID:37252199. |
cost-effectiveness of aripiprazole tablets with sensor versus oral atypical antipsychotics for the treatment of schizophrenia using a patient-level microsimulation modeling approach. |
2023-05-30 |
2023-08-14 |
Not clear |
| Daria A Kamaeva, Daria V Kazantseva, Anastasiia S Boiko, Irina A Mednova, Liudmila P Smirnova, Elena G Kornetova, Svetlana A Ivanov. The Influence of Antipsychotic Treatment on the Activity of Abzymes Targeting Myelin and Levels of Inflammation Markers in Patients with Schizophrenia. Biomedicines. vol 11. issue 4. 2023-05-16. PMID:37189796. |
the study included 40 patients with schizophrenia: 15 treated with first-generation antipsychotics and 25 treated with atypical antipsychotics for 6 weeks. |
2023-05-16 |
2023-08-14 |
Not clear |
| Gia Han Le, Emily S Gillissie, Taeho Greg Rhee, Bing Cao, Yazen Alnefeesi, Ziji Guo, Joshua D Di Vincenzo, Muhammad Youshay Jawad, Andrew M March, Ranuk Ramachandra, Leanna M W Lui, Roger S McIntyr. Efficacy, safety, and tolerability of ulotaront (SEP-363856, a trace amine-associated receptor 1 agonist) for the treatment of schizophrenia and other mental disorders with similar pathophysiology: a systematic review of preclinical and clinical trials. Expert opinion on investigational drugs. 2023-04-25. PMID:37096491. |
the classical approach to treat schizophrenia uses typical and atypical antipsychotics; however, limitations include low efficacy in mitigating negative symptoms and cognitive dysfunctions, and a range of adverse effects. |
2023-04-25 |
2023-08-14 |
Not clear |
| V V Tiguntsev, V I Gerasimova, E G Kornetova, O Yu Fedorenko, A N Kornetov, A A Goncharova, E G Poltavskaya, A S Boyk. [Association of the Level of Serum Prolactin with Polymorphic Variants of the GRIN2A, GPM3, and GPM7 Genes in Patients with Schizophrenia Taking Conventional and Atypical Antipsychotics]. Molekuliarnaia biologiia. vol 57. issue 1. 2023-03-28. PMID:36976738. |
[association of the level of serum prolactin with polymorphic variants of the grin2a, gpm3, and gpm7 genes in patients with schizophrenia taking conventional and atypical antipsychotics]. |
2023-03-28 |
2023-08-14 |
Not clear |
| V V Tiguntsev, V I Gerasimova, E G Kornetova, O Yu Fedorenko, A N Kornetov, A A Goncharova, E G Poltavskaya, A S Boyk. [Association of the Level of Serum Prolactin with Polymorphic Variants of the GRIN2A, GPM3, and GPM7 Genes in Patients with Schizophrenia Taking Conventional and Atypical Antipsychotics]. Molekuliarnaia biologiia. vol 57. issue 1. 2023-03-28. PMID:36976738. |
we formulated a hypothesis that polymorphic variants of the grin2a, grm3, and grm7 genes may be associated with the development of hyperprolactinemia in patients with schizophrenia taking conventional and atypical antipsychotics as basic treatment. |
2023-03-28 |
2023-08-14 |
Not clear |
| V V Tiguntsev, V I Gerasimova, E G Kornetova, O Yu Fedorenko, A N Kornetov, A A Goncharova, E G Poltavskaya, A S Boyk. [Association of the Level of Serum Prolactin with Polymorphic Variants of the GRIN2A, GPM3, and GPM7 Genes in Patients with Schizophrenia Taking Conventional and Atypical Antipsychotics]. Molekuliarnaia biologiia. vol 57. issue 1. 2023-03-28. PMID:36976738. |
an association of polymorphic variants of the grin2a, grm3, and grm7 genes with the development of hyperprolactinemia in patients with schizophrenia taking conventional and atypical antipsychotics has been established for the first time. |
2023-03-28 |
2023-08-14 |
Not clear |
| V V Tiguntsev, V I Gerasimova, E G Kornetova, O Yu Fedorenko, A N Kornetov, A A Goncharova, E G Poltavskaya, A S Boyk. [Association of the Level of Serum Prolactin with Polymorphic Variants of the GRIN2A, GPM3, and GPM7 Genes in Patients with Schizophrenia Taking Conventional and Atypical Antipsychotics]. Molekuliarnaia biologiia. vol 57. issue 1. 2023-03-28. PMID:36976738. |
the identified associations of polymorphic variants of the grin2a, grm3 and grm7 genes with the development of hyperprolactinemia in patients with schizophrenia taking conventional and atypical antipsychotics have been established for the first time. |
2023-03-28 |
2023-08-14 |
Not clear |
| Izabela Fulone, Marcus Tolentino Silva, Luciane Cruz Lope. Use of atypical antipsychotics in the treatment of schizophrenia in the Brazilian National Health System: a cohort study, 2008-2017. Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil. vol 32. issue 1. 2023-03-22. PMID:36946832. |
use of atypical antipsychotics in the treatment of schizophrenia in the brazilian national health system: a cohort study, 2008-2017. to investigate sociodemographic and clinical characteristics of users of atypical antipsychotics receiving care via the specialized component of pharmaceutical assistance (componente especializado da assistência farmacêutica - ceaf), for the treatment of schizophrenia in brazil, between 2008 and 2017. |
2023-03-22 |
2023-08-14 |
Not clear |
| Bram W C Storosum, Cedrine Steinz, Sem E Cohen, Taina Mattila, Wim van den Brink, Kit Roes, Lieuwe de Haan, Damiaan A J P Denys, Jasper B Zantvoor. Ethnic differences in response to atypical antipsychotics in patients with schizophrenia: individual patient data meta-analysis of randomised placebo-controlled registration trials submitted to the Dutch Medicines Evaluation Board. BJPsych open. vol 9. issue 2. 2023-03-02. PMID:36861144. |
ethnic differences in response to atypical antipsychotics in patients with schizophrenia: individual patient data meta-analysis of randomised placebo-controlled registration trials submitted to the dutch medicines evaluation board. |
2023-03-02 |
2023-08-14 |
Not clear |
| Moses Kule, Mark Mohan Kaggw. Adherence to Typical Antipsychotics among Patients with Schizophrenia in Uganda: A Cross-Sectional Study. Schizophrenia research and treatment. vol 2023. 2023-02-13. PMID:36778520. |
there has been a recent transition from typical to atypical antipsychotics in managing schizophrenia. |
2023-02-13 |
2023-08-14 |
Not clear |
| Ahmed M Abdelfattah, Sally A Abuelezz, Nevien Hendawy, Eman A Negm, Salwa Abd El Khalek Nawishy, Ahmed Mohamed Mohamed Khali. Sonic hedgehog pathway as a new target of atypical antipsychotics: Revisiting of amisulpride and aripiprazole effects in a rat model of schizophrenia. Life sciences. 2023-01-17. PMID:36649751. |
sonic hedgehog pathway as a new target of atypical antipsychotics: revisiting of amisulpride and aripiprazole effects in a rat model of schizophrenia. |
2023-01-17 |
2023-08-14 |
rat |
| Laura Morrison, Dee Lin, Carmela Benson, Isabelle Ghelerter, Maude Vermette-Laforme, Patrick Lefebvre, Dominic Pilo. Projecting the economic outcomes of switching patients with schizophrenia from oral atypical antipsychotics to once-monthly, once-every-3-months, and once-every-6-months paliperidone palmitate. Journal of managed care & specialty pharmacy. 2022-11-10. PMID:36354209. |
projecting the economic outcomes of switching patients with schizophrenia from oral atypical antipsychotics to once-monthly, once-every-3-months, and once-every-6-months paliperidone palmitate. |
2022-11-10 |
2023-08-14 |
Not clear |
| Jolanta Orzelska-Górka, Joanna Mikulska, Anna Wiszniewska, Grażyna Biał. New Atypical Antipsychotics in the Treatment of Schizophrenia and Depression. International journal of molecular sciences. vol 23. issue 18. 2022-09-23. PMID:36142523. |
new atypical antipsychotics in the treatment of schizophrenia and depression. |
2022-09-23 |
2023-08-14 |
Not clear |