Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Alejandro Carrasco-Poves, Silvia Ruiz-Espana, Claudia Regio Brambilla, Irene Neuner, Ravichandran Rajkumar, Shukti Ramkiran, Christoph Lerche, David Morata. Analysis of New Biomarkers for the Study of Schizophrenia Following a Radiomics Approach on MR and PET Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086347. |
the precision results were obtained classifying schizophrenia both in mr images (89% area under the curve (auc) in the posterior cingulate cortex) and with pet images (82% auc in the frontal cortex), being linear svm and naive bayes the classification models with the highest predictive power. |
2022-09-10 |
2023-08-14 |
human |
Alejandro Carrasco-Poves, Silvia Ruiz-Espana, Claudia Regio Brambilla, Irene Neuner, Ravichandran Rajkumar, Shukti Ramkiran, Christoph Lerche, David Morata. Analysis of New Biomarkers for the Study of Schizophrenia Following a Radiomics Approach on MR and PET Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086347. |
clinical relevance- the current study establishes a methodology to classify schizophrenia disease based on quantitative biomarkers using mr and pet images. |
2022-09-10 |
2023-08-14 |
human |
Emanuele F Osimo, Stefan P Brugger, E Louise Thomas, Oliver D Howe. A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia. NPJ schizophrenia. vol 8. issue 1. 2022-03-19. PMID:35304889. |
a cross-sectional mr study of body fat volumes and distribution in chronic schizophrenia. |
2022-03-19 |
2023-08-13 |
human |
Fan Ge, Zhenyu Huo, Yeling Liu, Xiaoqin Du, Rui Wang, Weiyi Lin, Runchen Wang, Jiana Chen, Yi Lu, Yaokai Wen, Huiying Cao, Siyue Shang, Md Eftekhar, Di G. Association between schizophrenia and prostate cancer risk: Results from a pool of cohort studies and Mendelian randomization analysis. Comprehensive psychiatry. vol 115. 2022-03-18. PMID:35303584. |
we performed a meta-analysis and a mendelian randomization (mr) analysis to evaluate the relationship and causality between schizophrenia and the risk of prostate cancer. |
2022-03-18 |
2023-08-13 |
Not clear |
Robert van Vore. Mr Sluggish Schizophrenia. BJPsych bulletin. vol 45. issue 4. 2021-10-15. PMID:34315552. |
mr sluggish schizophrenia. |
2021-10-15 |
2023-08-13 |
Not clear |
Yong Wu, Xiao-Lin Yu, Xiao Xiao, Ming Li, Yi L. Joint-Tissue Integrative Analysis Identified Hundreds of Schizophrenia Risk Genes. Molecular neurobiology. 2021-10-10. PMID:34628600. |
by leveraging multiple joint-tissue gene expression data and gwas data, we herein performed a transcriptome-wide association study (twas) and mendelian randomization (mr) analysis and identified 144 genes whose mrna levels were related to genetic risk of schizophrenia. |
2021-10-10 |
2023-08-13 |
Not clear |
Yuan Xiao, Wei Liao, Zhiliang Long, Bo Tao, Qiannan Zhao, Chunyan Luo, Carol A Tamminga, Matcheri S Keshavan, Godfrey D Pearlson, Brett A Clementz, Elliot S Gershon, Elena I Ivleva, Sarah K Keedy, Bharat B Biswal, Andrea Mechelli, Rebekka Lencer, John A Sweeney, Su Lui, Qiyong Gon. Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations. Schizophrenia bulletin. 2021-09-11. PMID:34508358. |
cross-sectional structural mr images of 163 never-treated first-episode schizophrenia patients (fes) and 133 chronically ill patients with midcourse schizophrenia from the bipolar and schizophrenia network for intermediate phenotypes (b-snip) consortium and a total of 403 healthy controls were recruited. |
2021-09-11 |
2023-08-13 |
human |
Yuan Xiao, Wei Liao, Zhiliang Long, Bo Tao, Qiannan Zhao, Chunyan Luo, Carol A Tamminga, Matcheri S Keshavan, Godfrey D Pearlson, Brett A Clementz, Elliot S Gershon, Elena I Ivleva, Sarah K Keedy, Bharat B Biswal, Andrea Mechelli, Rebekka Lencer, John A Sweeney, Su Lui, Qiyong Gon. Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations. Schizophrenia bulletin. 2021-09-11. PMID:34508358. |
regardless of clinical presentation and stage of illness, anatomic mr subgrouping biomarkers can separate neurobiologically distinct subgroups of schizophrenia patients, which represent an important and meaningful step forward in differentiating subtypes of patients for studies of illness neurobiology and potentially for clinical trials. |
2021-09-11 |
2023-08-13 |
human |
Shinsuke Koike, Akiko Uematsu, Daiki Sasabayashi, Norihide Maikusa, Tsutomu Takahashi, Kazutaka Ohi, Shinichiro Nakajima, Yoshihiro Noda, Yoji Hiran. Recent Advances and Future Directions in Brain MR Imaging Studies in Schizophrenia: Toward Elucidating Brain Pathology and Developing Clinical Tools. Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 2021-08-19. PMID:34408115. |
recent advances and future directions in brain mr imaging studies in schizophrenia: toward elucidating brain pathology and developing clinical tools. |
2021-08-19 |
2023-08-13 |
human |
Wasana Ediri Arachchi, Yanmin Peng, Xi Zhang, Wen Qin, Chuanjun Zhuo, Chunshui Yu, Meng Lian. A Systematic Characterization of Structural Brain Changes in Schizophrenia. Neuroscience bulletin. vol 36. issue 10. 2021-07-27. PMID:32495122. |
here, we performed vbm, tbm, and pbt analyses on t1-weighted brain mr images acquired from 116 patients with schizophrenia and 116 healthy controls. |
2021-07-27 |
2023-08-13 |
Not clear |
Zhiyong Cui, Xiangyu Meng, Siying Zhuang, Zhaorui Liu, Fang Zhou, Yun Tia. Schizophrenia, Bipolar Disorder, and Alzheimer's Disease are not Causal Factors of Bone Mineral Density: A Mendelian Randomization Analysis. Calcified tissue international. vol 106. issue 2. 2021-06-09. PMID:31679055. |
the mr results also revealed that directional pleiotropy was unlikely to bias the causality (e.g., schizophrenia and fn-bmd, intercept = 0.0023, p = 0.6887), and no evidence of heterogeneity was found between the genetic variants (e.g., schizophrenia and fn-bmd, mr-egger q = 46.1502, i |
2021-06-09 |
2023-08-13 |
Not clear |
Colleen P E Rollins, Jane R Garrison, Maite Arribas, Aida Seyedsalehi, Zhi Li, Raymond C K Chan, Junwei Yang, Duo Wang, Pietro Liò, Chao Yan, Zheng-Hui Yi, Arnaud Cachia, Rachel Upthegrove, Bill Deakin, Jon S Simons, Graham K Murray, John Sucklin. Evidence in cortical folding patterns for prenatal predispositions to hallucinations in schizophrenia. Translational psychiatry. vol 10. issue 1. 2021-05-18. PMID:33159044. |
we studied two independent datasets of patients with schizophrenia who underwent clinical assessment and 3t mr imaging from the united kingdom and shanghai, china (n = 181 combined) and 63 healthy controls from shanghai. |
2021-05-18 |
2023-08-13 |
human |
Hannah J Jones, David Martin, Sarah J Lewis, George Davey Smith, Michael C O'Donovan, Michael J Owen, James T R Walters, Stanley Zammi. A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 183. issue 6. 2021-05-14. PMID:32578352. |
we therefore aimed to investigate whether anxiety-related phenotypes lie on the causal pathway to schizophrenia using mendelian randomization (mr). |
2021-05-14 |
2023-08-13 |
Not clear |
Hannah J Jones, David Martin, Sarah J Lewis, George Davey Smith, Michael C O'Donovan, Michael J Owen, James T R Walters, Stanley Zammi. A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 183. issue 6. 2021-05-14. PMID:32578352. |
mr provided evidence of a causal effect of neuroticism on schizophrenia (ivw odds ratio [or]: 1.33, 95% confidence interval [ci]: 1.12-1.59), but only weak evidence of a causal effect of anxiety on schizophrenia (ivw or: 1.10, 95% ci: 1.01-1.19). |
2021-05-14 |
2023-08-13 |
Not clear |
Jurjen J Luykx, Bochao D Li. Are psychiatric disorders risk factors for COVID-19 susceptibility and severity? a two-sample, bidirectional, univariable, and multivariable Mendelian Randomization study. Translational psychiatry. vol 11. issue 1. 2021-04-23. PMID:33833219. |
in single-variable generalized summary mr analysis, the most significant and only bonferroni-corrected significant result was found for genetic liability to bip-scz (a combined gwas of bipolar disorder and schizophrenia as cases vs. controls) increasing risk of covid-19 (or = 1.17, 95% ci, 1.06-1.28). |
2021-04-23 |
2023-08-13 |
Not clear |
Jurjen J Luykx, Bochao D Li. Are psychiatric disorders risk factors for COVID-19 susceptibility and severity? a two-sample, bidirectional, univariable, and multivariable Mendelian Randomization study. Translational psychiatry. vol 11. issue 1. 2021-04-23. PMID:33833219. |
in conclusion, while genetic liability to bipolar disorder and schizophrenia combined slightly increased covid-19 susceptibility in one univariable analysis, other mr and multivariable analyses could only confirm genetic underpinnings of bmi to be causally implicated in covid-19 susceptibility. |
2021-04-23 |
2023-08-13 |
Not clear |
D Malaspina, E Lotan, H Rusinek, S A Perez, J Walsh-Messinger, T M Kranz, O Gone. Preliminary Findings Associate Hippocampal AJNR. American journal of neuroradiology. vol 42. issue 1. 2021-03-22. PMID:33184071. |
preliminary findings associate hippocampal previous hippocampal proton mr spectroscopic imaging distinguished patients with schizophrenia from controls by elevated cr levels and significantly more variable naa and cho concentrations. |
2021-03-22 |
2023-08-13 |
Not clear |
Justyna Beresniewicz, Alexander R Craven, Kenneth Hugdahl, Else-Marie Løberg, Rune Andreas Kroken, Erik Johnsen, Renate Grüne. White Matter Microstructural Differences between Hallucinating and Non-Hallucinating Schizophrenia Spectrum Patients. Diagnostics (Basel, Switzerland). vol 11. issue 1. 2021-02-18. PMID:33477803. |
we used a magnetic resonance diffusion tensor imaging (mr dti) sequence and tract-based spatial statistics (tbss) to explore white matter differences between two subtypes of schizophrenia patients; 44 hallucinating (avh+) and 13 non-hallucinating (avh-), compared to 13 avh- matched controls and 44 avh+ matched controls. |
2021-02-18 |
2023-08-13 |
Not clear |
Heli Sun, Xue Gao, Ximei Que, Long Liu, Jinsha Ma, Simin He, Qian Gao, Tong Wan. The causal relationships of device-measured physical activity with bipolar disorder and schizophrenia in adults: A 2-Sample mendelian randomization study. Journal of affective disorders. vol 263. 2021-02-15. PMID:31780129. |
to examine the causal association of device-measured physical activity with bipolar disorder (bip) and schizophrenia (scz) in adults by performing 2-sample mr analysis. |
2021-02-15 |
2023-08-13 |
Not clear |
Roxanna Korologou-Linden, Genevieve M Leyden, Caroline L Relton, Rebecca C Richmond, Tom G Richardso. Multi-omics analyses of cognitive traits and psychiatric disorders highlights brain-dependent mechanisms. Human molecular genetics. 2021-01-22. PMID:33481009. |
we have applied the principles of mendelian randomization (mr) to investigate whether brain-derived gene expression (n = 1194) may be responsible for mediating the effect of genetic variants on eight cognitive and psychological outcomes (attention deficit hyperactivity disorder (adhd), alzheimer's disease, bipolar disorder, depression, intelligence, insomnia, neuroticism and schizophrenia). |
2021-01-22 |
2023-08-13 |
Not clear |