| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiang Xu, Mengjing Cai, Yuan Ji, Juanwei Ma, Jiawei Liu, Qiyu Zhao, Yayuan Chen, Yao Zhao, Yijing Zhang, He Wang, Lining Guo, Kaizhong Xue, Zirui Wang, Mengge Liu, Chunyang Wang, Dan Zhu, Feng Li. Identifying the mediating role of socioeconomic status on the relationship between schizophrenia and major depressive disorder: a Mendelian randomisation analysis. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-08-29. PMID:37644044. |
mr analyses showed that genetically predicted schizophrenia was associated with an increased risk of mdd (ivw odds ratio [or] = 1.137 [95% ci 1.095, 1.181]). |
2023-08-29 |
2023-09-07 |
Not clear |
| Qiang Xu, Mengjing Cai, Yuan Ji, Juanwei Ma, Jiawei Liu, Qiyu Zhao, Yayuan Chen, Yao Zhao, Yijing Zhang, He Wang, Lining Guo, Kaizhong Xue, Zirui Wang, Mengge Liu, Chunyang Wang, Dan Zhu, Feng Li. Identifying the mediating role of socioeconomic status on the relationship between schizophrenia and major depressive disorder: a Mendelian randomisation analysis. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-08-29. PMID:37644044. |
the mediation analysis via the two-step mr method revealed that the causal effect of schizophrenia on mdd was partly mediated by the townsend deprivation index with a proportion of 10.27%, but no significant mediation effect was found of ses on the causal effect of mdd on schizophrenia. |
2023-08-29 |
2023-09-07 |
Not clear |
| Chengdong Wang, Dongdong Zhu, Dongjun Zhang, Xiaowei Zuo, Lei Yao, Teng Liu, Xiaodan Ge, Chenlu He, Yuan Zhou, Ziyuan She. Causal role of immune cells in schizophrenia: Mendelian randomization (MR) study. BMC psychiatry. vol 23. issue 1. 2023-08-15. PMID:37582716. |
causal role of immune cells in schizophrenia: mendelian randomization (mr) study. |
2023-08-15 |
2023-09-07 |
Not clear |
| Siying Lin, Haoyang Zhang, Mengling Qi, David N Cooper, Yuedong Yang, Yuanhao Yang, Huiying Zha. Inferring the genetic relationship between brain imaging-derived phenotypes and risk of complex diseases by Mendelian randomization and genome-wide colocalization. NeuroImage. 2023-08-14. PMID:37579999. |
applications of mendelian randomization (mr) identified significant putative causal effects of multiple region-specific brain idps in relation to the increased risks for amyotrophic lateral sclerosis (als), major depressive disorder (mdd), autism spectrum disorder (asd) and schizophrenia (scz). |
2023-08-14 |
2023-09-07 |
Not clear |
| Natalia Śmierciak, Wirginia Krzyściak, Marta Szwajca, Paulina Karcz, Amira Bryll, Tadeusz J Popiela, Paulina Donicz, Aleksander Turek, Veronika Aleksandrovych, Maciej Pileck. Benefits and Meaning of Lipids Profile in Relation to Oxidative Balance and Brain Morphology in Schizophrenia. International journal of molecular sciences. vol 24. issue 14. 2023-07-29. PMID:37511134. |
positive significant correlations between serum high-density cholesterol and anterior cingulate cortex, unique brain area for schizophrenia pathophysiology, mr spectroscopy signals, and diffusion have been revealed. |
2023-07-29 |
2023-08-14 |
human |
| b' \\xc5\\x9eerife Genge\\xc3\\xa7 Benli, Merve Anda\\xc3\\xa. Constructing the Schizophrenia Recognition Method Employing GLCM Features from Multiple Brain Regions and Machine Learning Techniques. Diagnostics (Basel, Switzerland). vol 13. issue 13. 2023-07-14. PMID:37443534.' |
various types of magnetic resonance (mr) images have the potential to serve as biomarkers for schizophrenia. |
2023-07-14 |
2023-08-14 |
Not clear |
| b' \\xc5\\x9eerife Genge\\xc3\\xa7 Benli, Merve Anda\\xc3\\xa. Constructing the Schizophrenia Recognition Method Employing GLCM Features from Multiple Brain Regions and Machine Learning Techniques. Diagnostics (Basel, Switzerland). vol 13. issue 13. 2023-07-14. PMID:37443534.' |
the aim of this study is to numerically analyze differences in the textural characteristics that may occur in the bilateral amygdala, caudate, pallidum, putamen, and thalamus regions of the brain between individuals with schizophrenia and healthy controls via structural mr images. |
2023-07-14 |
2023-08-14 |
Not clear |
| Carlos A Larrauri, Philip D Harvey, John M Kan. A Patient-Clinician Discussion of Current Challenges in Schizophrenia Part 1: Addressing Daily Functioning and Cognitive Impairments Associated with Schizophrenia [Podcast]. Neuropsychiatric disease and treatment. vol 19. 2023-06-09. PMID:37292181. |
dr john m. kane discusses cognitive impairments in schizophrenia with fellow expert dr philip d. harvey and patient advocate and mental health clinician, mr carlos a. larrauri, who was diagnosed with schizophrenia. |
2023-06-09 |
2023-08-14 |
Not clear |
| Matthew Racher, William Carpenter, John M Kan. A Patient-Clinician Discussion of Current Challenges in Schizophrenia Part 2: Negative Symptoms in Schizophrenia [Podcast]. Neuropsychiatric disease and treatment. vol 19. 2023-06-09. PMID:37292182. |
dr john kane discusses negative symptoms in schizophrenia alongside fellow expert, dr william carpenter, and mr matthew racher, a certified recovery peer specialist and dedicated advocate for people living with schizophrenia, who is currently studying for his master of social work (msw) in miami, florida. |
2023-06-09 |
2023-08-14 |
Not clear |
| Matthew Racher, William Carpenter, John M Kan. A Patient-Clinician Discussion of Current Challenges in Schizophrenia Part 2: Negative Symptoms in Schizophrenia [Podcast]. Neuropsychiatric disease and treatment. vol 19. 2023-06-09. PMID:37292182. |
mr racher provides a unique patient perspective to this discussion, drawing on his own daily experiences of living with negative symptoms, as well as offering positive insights from his recovery from schizophrenia. |
2023-06-09 |
2023-08-14 |
Not clear |
| Mengyu Pan, James M Roe, Ron Nudel, Andrew J Schork, Olena Iakunchykova, Anders M Fjell, Kristine B Walhovd, Thomas Werge, Chi-Hua Chen, Michael E Benros, Yunpeng Wan. Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225692. |
we applied two-sample mendelian randomization (mr) on the association statistics from genome-wide association studies (gwas) for circulating s100b levels measured 5-7 days after birth (the ipsych sample) and in an older adult sample (mean age, 72.5 years; the lothian sample), upon those derived from major depression disorder (mdd), schizophrenia (scz), bipolar disorder (bip), autism spectral disorder (asd), alzheimer's disease (ad), and parkinson's disease (pd). |
2023-05-24 |
2023-08-14 |
Not clear |
| Noah Lorincz-Comi, Yihe Yang, Gen Li, Xiaofeng Zh. MRBEE: A novel bias-corrected multivariable Mendelian Randomization method. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066391. |
in two independent real data analyses, we discovered that the causal effect of bmi on coronary artery disease risk is entirely mediated by blood pressure, and that existing mr methods may underestimate the causal effect of cannabis use disorder on schizophrenia risk compared to mrbee. |
2023-04-17 |
2023-08-14 |
human |
| Xiaofeng Zhu, Noah Lorincz-Comi, Yihe Yang, Gen L. MRBEE: A novel bias-corrected multivariable Mendelian Randomization method. Research square. 2023-02-13. PMID:36778480. |
in two independent real data analyses, we observed that the causal effect of bmi on coronary artery disease risk is completely mediated by blood pressure, and that existing mr methods drastically underestimate the causal effect of cannabis use disorder on schizophrenia risk compared to mrbee. |
2023-02-13 |
2023-08-14 |
human |
| Hao Zhao, Xue Han, Xuening Zhang, Lingjiang Li, Yanzhi Li, Wanxin Wang, Roger S McIntyre, Kayla M Teopiz, Lan Guo, Ciyong L. Dissecting Causal Associations of Diet-Derived Circulating Antioxidants with Six Major Mental Disorders: A Mendelian Randomization Study. Antioxidants (Basel, Switzerland). vol 12. issue 1. 2023-01-21. PMID:36671024. |
mendelian randomization (mr) analyses were conducted using summary-level statistics from genome-wide association studies (gwass) to explore whether genetically determined absolute circulating antioxidants (i.e., ascorbate, retinol, β-carotene, and lycopene) and metabolites (i.e., α- and γ-tocopherol, ascorbate, and retinol) were causally associated with the risk of six major mental disorders, including anxiety disorders (ad), major depressive disorder (mdd), bipolar disorder (bip), schizophrenia (scz), post-traumatic stress disorder (ptsd), and obsessive-compulsive disorder (ocd). |
2023-01-21 |
2023-08-14 |
human |
| Ning Ma, Renxi Wan. Mendelian randomization study on the effect of tumor necrosis factor on schizophrenia. Psychiatric genetics. vol 32. issue 6. 2022-11-10. PMID:36354138. |
the present two-sample mendelian randomization (mr) study aims to identify the causal link between tnf and schizophrenia. |
2022-11-10 |
2023-08-14 |
Not clear |
| Jing Guo, Ke Yu, Shan-Shan Dong, Shi Yao, Yu Rong, Hao Wu, Kun Zhang, Feng Jiang, Yi-Xiao Chen, Yan Guo, Tie-Lin Yan. Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders. Nature neuroscience. 2022-10-10. PMID:36216997. |
reverse mr indicated that only genetically predicted schizophrenia was positively associated with two idps, the cortical surface area and the volume of the right pars orbitalis. |
2022-10-10 |
2023-08-14 |
Not clear |
| Jiewei Liu, Yuqi Cheng, Ming Li, Zhijun Zhang, Tao Li, Xiong-Jian Lu. Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-09-16. PMID:36114287. |
of note, mapk3 and hla-drb1 were supported by both transcriptome and proteome-wide mr analyses, suggesting that these two proteins are promising therapeutic targets for schizophrenia. |
2022-09-16 |
2023-08-14 |
Not clear |
| Alejandro Carrasco-Poves, Silvia Ruiz-Espana, Claudia Regio Brambilla, Irene Neuner, Ravichandran Rajkumar, Shukti Ramkiran, Christoph Lerche, David Morata. Analysis of New Biomarkers for the Study of Schizophrenia Following a Radiomics Approach on MR and PET Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086347. |
analysis of new biomarkers for the study of schizophrenia following a radiomics approach on mr and pet imaging. |
2022-09-10 |
2023-08-14 |
human |
| Alejandro Carrasco-Poves, Silvia Ruiz-Espana, Claudia Regio Brambilla, Irene Neuner, Ravichandran Rajkumar, Shukti Ramkiran, Christoph Lerche, David Morata. Analysis of New Biomarkers for the Study of Schizophrenia Following a Radiomics Approach on MR and PET Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086347. |
the precision results were obtained classifying schizophrenia both in mr images (89% area under the curve (auc) in the posterior cingulate cortex) and with pet images (82% auc in the frontal cortex), being linear svm and naive bayes the classification models with the highest predictive power. |
2022-09-10 |
2023-08-14 |
human |
| Alejandro Carrasco-Poves, Silvia Ruiz-Espana, Claudia Regio Brambilla, Irene Neuner, Ravichandran Rajkumar, Shukti Ramkiran, Christoph Lerche, David Morata. Analysis of New Biomarkers for the Study of Schizophrenia Following a Radiomics Approach on MR and PET Imaging. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086347. |
clinical relevance- the current study establishes a methodology to classify schizophrenia disease based on quantitative biomarkers using mr and pet images. |
2022-09-10 |
2023-08-14 |
human |