| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yixin Zhao, Weilong Guo, Jiansong Zhou, Xiaoping Wan. Schizophrenia and risk preference: a bidirectional two-sample mendelian randomization study. European archives of psychiatry and clinical neuroscience. 2024-06-24. PMID:38914854. |
however, the causality and direction of this association are not clear; therefore, we used mendelian randomization (mr) to examine the potential bidirectional relationship between risk preference and schizophrenia. |
2024-06-24 |
2024-06-27 |
human |
| Shuyang Lin, Bei Gao, Rui Xu, Hongming Shang, Yan Xiong, Jiayi Zhou, Zhe Yang, Chao Jiang, Shumei Ya. Multiple myeloma, IL6, and risk of schizophrenia: A Mendelian randomization, transcriptome, and Bayesian colocalization study. EJHaem. vol 5. issue 3. 2024-06-19. PMID:38895088. |
this exploratory study employed bidirectional mendelian randomization (mr) analysis to investigate the causal relationships between mm and inflammatory diseases, including atherosclerosis, asthma, ankylosing spondylitis, alzheimer's disease (ad), parkinson's disease (pd), sarcoidosis, inflammatory bowel disease, nonalcoholic fatty liver disease, type ii diabetes, and schizophrenia (sz). |
2024-06-19 |
2024-06-21 |
Not clear |
| Andrea N Georgiou, Konstantinos Voskarides, Panos Zanos, Andreas Chatzittofi. Investigating the shared genetic basis and causal relationships between mucosa-associated lymphoid tissue inflammation and psychiatric disorders. Frontiers in psychiatry. vol 15. 2024-05-14. PMID:38742127. |
in the present study, we investigated this association, using as proxies genetically predicted tonsillectomy, appendectomy and appendicitis on psychiatric disorders including major depressive disorder (mdd), schizophrenia (scz), bipolar depression (bd) and anxiety (anx) via a two-sample mendelian randomization (mr) analysis. |
2024-05-14 |
2024-05-27 |
Not clear |
| Huang-Hui Liu, Yao Gao, Dan Xu, Xin-Zhe Du, Si-Meng Wei, Jian-Zhen Hu, Yong Xu, Liu Sh. Asparagine reduces the risk of schizophrenia: a bidirectional two-sample mendelian randomization study of aspartate, asparagine and schizophrenia. BMC psychiatry. vol 24. issue 1. 2024-04-19. PMID:38641826. |
this study used a bidirectional two-sample mendelian randomization (mr) method to explore the causal relationship between aspartate and asparagine with schizophrenia. |
2024-04-19 |
2024-04-22 |
Not clear |
| Lara Hamzehpour, Tamara Bohn, Valentin Dutsch, Lucia Jaspers, Oliver Grim. From brain to body: exploring the connection between altered reward processing and physical fitness in schizophrenia. Psychiatry research. vol 335. 2024-03-31. PMID:38555826. |
we implemented the monetary incentive delay task in a mr scanner and a fitness test battery to compare schizophrenia patients (sz, n = 43) with sex- and age-matched healthy controls (hc, n = 36) as to reward processing and their physical fitness. |
2024-03-31 |
2024-04-03 |
Not clear |
| Xiaohan Chen, Shudan Wang, Weiyu She. The causal relationship between severe mental illness and risk of lung carcinoma. Medicine. vol 103. issue 11. 2024-03-15. PMID:38489734. |
in two-sample mr, we identified schizophrenia as a risk factor for lc (or = 1.06, 95% ci 1.02-1.11, p = 3.48e-03), while mdd (or = 1.18, 95% ci 0.98-1.42, p = .07) and bd (or = 1.07, 95% ci 0.99-1.15, p = .09) showed no significant association with lc. |
2024-03-15 |
2024-03-18 |
Not clear |
| Hongjun Ba, Lili Zhang, Huimin Peng, Xiufang He, Yao Wan. Causal links between sedentary behavior, physical activity, and psychiatric disorders: a Mendelian randomization study. Annals of general psychiatry. vol 23. issue 1. 2024-02-29. PMID:38424581. |
hence, the objective of this research was to investigate the possible causal relationship between sedentary behavior, physical activity, and the susceptibility to psychiatric disorder (depression, schizophrenia and bipolar disorder), utilizing a two-sample mendelian randomization (mr) approach. |
2024-02-29 |
2024-03-03 |
Not clear |
| Shane Crinion, Derek W Morris, Lorna M Lope. Neuropsychiatric disorders, chronotype and sleep: A narrative review of GWAS findings and the application of Mendelian randomization to investigate causal relationships. Genes, brain, and behavior. vol 23. issue 1. 2024-02-15. PMID:38359178. |
mr studies identified evidence of a causal role for five neuropsychiatric disorders and symptoms (attention deficit hyperactivity disorder, bipolar disorder, depressive symptoms, major depressive disorder and schizophrenia) on sleep-related phenotypes and evidence of a causal role for five sleep-related phenotypes (daytime napping, insomnia, morning person, long sleep duration and sleep duration) on risk for neuropsychiatric disorders. |
2024-02-15 |
2024-02-18 |
Not clear |
| Perry B M Leung, Zipeng Liu, Yuanxin Zhong, Justin D Tubbs, Marta Di Forti, Robin M Murray, Hon- Cheong So, Pak C Sham, Simon S Y Lu. Bidirectional two-sample Mendelian randomization study of differential white blood cell counts and schizophrenia. Brain, behavior, and immunity. 2024-02-14. PMID:38355025. |
mendelian randomization (mr) is a useful method for examining the directions of genetically-predicted relationships between schizophrenia and wbc. |
2024-02-14 |
2024-02-17 |
Not clear |
| Haiman Guo, Shuyi Jian, Yubin Zhou, Xiaoyi Chen, Jinbiao Chen, Jing Zhou, Yuanyuan Huang, Guolin Ma, Xiaobo Li, Yuping Ning, Fengchun Wu, Kai W. Discriminative analysis of schizophrenia patients using an integrated model combining 3D CNN with 2D CNN: A multimodal MR image and connectomics analysis. Brain research bulletin. 2023-12-17. PMID:38104672. |
discriminative analysis of schizophrenia patients using an integrated model combining 3d cnn with 2d cnn: a multimodal mr image and connectomics analysis. |
2023-12-17 |
2023-12-21 |
Not clear |
| Chuanjun Zhuo, Qiuyu Zhang, Lina Wang, Xiaoyan Ma, Ranli Li, Jing Ping, Jingjing Zhu, Hongjun Tian, Deguo Jian. Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia. CNS drugs. 2023-12-15. PMID:38097908. |
the objective of this narrative review was to synthesize important studies, including mendelian randomization (mr) analyses that have integrated genome-wide association studies (gwas), as well as results from in vitro models, in vivo models, and observational studies of patients with schizophrenia. |
2023-12-15 |
2023-12-17 |
Not clear |
| Chuanjun Zhuo, Qiuyu Zhang, Lina Wang, Xiaoyan Ma, Ranli Li, Jing Ping, Jingjing Zhu, Hongjun Tian, Deguo Jian. Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia. CNS drugs. 2023-12-15. PMID:38097908. |
both gwas and mr studies have found that schizophrenia and t2d/insulin resistance share genetic risk factors, and this may mediate a connection between peripheral or brain insulin resistance and t2d with cognition impairment and an increased risk of developing prediabetes and t2d in schizophrenia. |
2023-12-15 |
2023-12-17 |
Not clear |
| Kenneth S Kendler, Astrid Kle. Bruno Schulz's 1930 article "The Hereditary Relationships of Old-Age Paranoid Psychosis". American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2023-11-16. PMID:37968572. |
the mr of schizophrenia in these four groups of relatives varied from 0 to 2.4% with 3 of 4 somewhat higher than population expectations but much lower than parallel results in relatives of schizophrenics. |
2023-11-16 |
2023-11-20 |
Not clear |
| Sungyeon Kim, Seungyoon Na. The causal relationship of colorectal cancer on schizophrenia: A Mendelian randomization study. Medicine. vol 102. issue 40. 2023-10-06. PMID:37800808. |
a causal effect of schizophrenia on cancer was observed using mendelian randomization (mr) analysis. |
2023-10-06 |
2023-10-07 |
Not clear |
| Sungyeon Kim, Seungyoon Na. The causal relationship of colorectal cancer on schizophrenia: A Mendelian randomization study. Medicine. vol 102. issue 40. 2023-10-06. PMID:37800808. |
however, the causal effect of colorectal cancer on schizophrenia has not been studied using mr analysis. |
2023-10-06 |
2023-10-07 |
Not clear |
| Sungyeon Kim, Seungyoon Na. The causal relationship of colorectal cancer on schizophrenia: A Mendelian randomization study. Medicine. vol 102. issue 40. 2023-10-06. PMID:37800808. |
therefore, we performed mr analysis to investigate the causal effects of colorectal cancer on schizophrenia. |
2023-10-06 |
2023-10-07 |
Not clear |
| Ningning Jia, Lin Dong, Qingxing Lu, Xinwei Li, Mengdi Jin, Xuyuan Yin, Zhenhua Zhu, Qiufang Jia, Caifang Ji, Li Hui, Qiong Y. The causal effect of schizophrenia on fractures and bone mineral density: a comprehensive two-sample Mendelian randomization study of European ancestry. BMC psychiatry. vol 23. issue 1. 2023-09-24. PMID:37743466. |
this study aimed to test the causal effects between schizophrenia and fractures as well as aberrant bmd by conducting mendelian randomization (mr) analyses. |
2023-09-24 |
2023-10-07 |
Not clear |
| Mengmeng Ou, Zhiqiang Du, Ying Jiang, Qin Zhou, Jianming Yuan, Lin Tian, Haohao Zh. Causal relationship between schizophrenia and sex hormone binding globulin: A Mendelian randomization study. Schizophrenia research. 2023-09-21. PMID:37735050. |
however, the causal relationship between shbg levels and schizophrenia remains unclear, this study aimed to investigate the causal relationship based on two-sample mendelian randomization (mr) analysis. |
2023-09-21 |
2023-10-07 |
Not clear |
| Qiang Xu, Mengjing Cai, Yuan Ji, Juanwei Ma, Jiawei Liu, Qiyu Zhao, Yayuan Chen, Yao Zhao, Yijing Zhang, He Wang, Lining Guo, Kaizhong Xue, Zirui Wang, Mengge Liu, Chunyang Wang, Dan Zhu, Feng Li. Identifying the mediating role of socioeconomic status on the relationship between schizophrenia and major depressive disorder: a Mendelian randomisation analysis. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-08-29. PMID:37644044. |
two-sample mendelian randomization (mr) analyses were conducted to explore the bidirectional causal relationship between schizophrenia and mdd with the largest sample size of european ancestry from public genome-wide association studies (sample size ranged from 130,644 to 480,359). |
2023-08-29 |
2023-09-07 |
Not clear |
| Qiang Xu, Mengjing Cai, Yuan Ji, Juanwei Ma, Jiawei Liu, Qiyu Zhao, Yayuan Chen, Yao Zhao, Yijing Zhang, He Wang, Lining Guo, Kaizhong Xue, Zirui Wang, Mengge Liu, Chunyang Wang, Dan Zhu, Feng Li. Identifying the mediating role of socioeconomic status on the relationship between schizophrenia and major depressive disorder: a Mendelian randomisation analysis. Schizophrenia (Heidelberg, Germany). vol 9. issue 1. 2023-08-29. PMID:37644044. |
mr analyses showed that genetically predicted schizophrenia was associated with an increased risk of mdd (ivw odds ratio [or] = 1.137 [95% ci 1.095, 1.181]). |
2023-08-29 |
2023-09-07 |
Not clear |