| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julia A Weiler, Christian Bellebaum, Martin Brüne, Georg Juckel, Irene Dau. Impairment of probabilistic reward-based learning in schizophrenia. Neuropsychology. vol 23. issue 5. 2009-10-16. PMID:19702411. |
exploratory analysis of only the subgroup of individuals with schizophrenia who showed significant learning during acquisition yielded deficits in reversal learning with low reward magnitudes only. |
2009-10-16 |
2023-08-12 |
Not clear |
| Julia A Weiler, Christian Bellebaum, Martin Brüne, Georg Juckel, Irene Dau. Impairment of probabilistic reward-based learning in schizophrenia. Neuropsychology. vol 23. issue 5. 2009-10-16. PMID:19702411. |
in summary, although there was evidence of intact basic processing of reward magnitudes, individuals with schizophrenia were impaired at using this feedback for the adaptive guidance of behavior. |
2009-10-16 |
2023-08-12 |
Not clear |
| Florian Schlagenhauf, Philipp Sterzer, Katharina Schmack, Martina Ballmaier, Michael Rapp, Jana Wrase, Georg Juckel, Jürgen Gallinat, Andreas Hein. Reward feedback alterations in unmedicated schizophrenia patients: relevance for delusions. Biological psychiatry. vol 65. issue 12. 2009-08-20. PMID:19195646. |
reward feedback alterations in unmedicated schizophrenia patients: relevance for delusions. |
2009-08-20 |
2023-08-12 |
Not clear |
| James M Gold, James A Waltz, Kristen J Prentice, Sarah E Morris, Erin A Heere. Reward processing in schizophrenia: a deficit in the representation of value. Schizophrenia bulletin. vol 34. issue 5. 2008-12-30. PMID:18591195. |
reward processing in schizophrenia: a deficit in the representation of value. |
2008-12-30 |
2023-08-12 |
human |
| James M Gold, James A Waltz, Kristen J Prentice, Sarah E Morris, Erin A Heere. Reward processing in schizophrenia: a deficit in the representation of value. Schizophrenia bulletin. vol 34. issue 5. 2008-12-30. PMID:18591195. |
patients with schizophrenia demonstrate deficits in motivation and learning that suggest impairment in different aspects of the reward system. |
2008-12-30 |
2023-08-12 |
human |
| Preethi Premkumar, Dominic Fannon, Elizabeth Kuipers, Andrew Simmons, Sophia Frangou, Veena Kumar. Emotional decision-making and its dissociable components in schizophrenia and schizoaffective disorder: a behavioural and MRI investigation. Neuropsychologia. vol 46. issue 7. 2008-08-13. PMID:18329673. |
it is concluded that (i) poor memory, rather than less attention to reward or impulsivity, contributes to igt performance deficit, and (ii) the relationship of igt performance and its components with gmvs especially in the frontal and temporal lobes is lost or attenuated in schizophrenia. |
2008-08-13 |
2023-08-12 |
Not clear |
| Jimmy Jensen, Matthäus Willeit, Robert B Zipursky, Ioulia Savina, Andrew J Smith, Mahesh Menon, Adrian P Crawley, Shitij Kapu. The formation of abnormal associations in schizophrenia: neural and behavioral evidence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 3. 2008-04-23. PMID:17473838. |
it is hypothesized that due to an abnormal functioning of the reward system patients with schizophrenia form context-inappropriate associations. |
2008-04-23 |
2023-08-12 |
Not clear |
| Alan I Green, Douglas L Noordsy, Mary F Brunette, Christopher O'Keef. Substance abuse and schizophrenia: pharmacotherapeutic intervention. Journal of substance abuse treatment. vol 34. issue 1. 2008-04-03. PMID:17574793. |
a neurobiological formulation is discussed, suggesting that the use of substances in patients with schizophrenia may be based on a dysfunction within the dopamine-mediated brain reward circuitry and that clozapine, in particular, may potentially ameliorate this dysfunction and lessen the desire for substance use. |
2008-04-03 |
2023-08-12 |
Not clear |
| Allen E Thornton, Vanessa G Boudreau, Stephanie Y Griffiths, Todd S Woodward, Tanya Fawkes-Kirby, William G Hone. The impact of monetary reward on memory in schizophrenia spectrum disorder. Neuropsychology. vol 21. issue 5. 2007-11-28. PMID:17784811. |
although healthy individuals benefited from reward at a high vwm load level, schizophrenia patients exhibited no reward-related improvements in vwm. |
2007-11-28 |
2023-08-12 |
human |
| P Kirsch, S Ronshausen, D Mier, B Gallhofe. The influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients. Pharmacopsychiatry. vol 40. issue 5. 2007-11-20. PMID:17874350. |
the influence of antipsychotic treatment on brain reward system reactivity in schizophrenia patients. |
2007-11-20 |
2023-08-12 |
Not clear |
| Alan I Gree. Pharmacotherapy for schizophrenia and co-occurring substance use disorders. Neurotoxicity research. vol 11. issue 1. 2007-05-22. PMID:17449446. |
our group has suggested that the brain reward circuit dysfunction model, which may incorporate aspects of all of these models, may help direct research aimed at developing new pharmacological treatments for patients with schizophrenia and co-occurring sud. |
2007-05-22 |
2023-08-12 |
Not clear |
| Joseph T Coyl. Substance use disorders and Schizophrenia: a question of shared glutamatergic mechanisms. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197372. |
given the role of nmda receptors in the reward circuitry and in substance dependence, it is reasonable to speculate that nmda receptor dysfunction is a shared pathologic process in schizophrenia and co-morbid suds. |
2007-03-20 |
2023-08-12 |
human |
| John H Krystal, D Cyril D'Souza, Jürgen Gallinat, Naomi Driesen, Anissa Abi-Dargham, Ismene Petrakis, Andreas Heinz, Godfrey Pearlso. The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia. Neurotoxicity research. vol 10. issue 3-4. 2007-03-20. PMID:17197373. |
the distortions in reward processing and altered response to substances of abuse also increase the likelihood that individuals with schizophrenia will self-medicate their subjective distress with abused substances. |
2007-03-20 |
2023-08-12 |
Not clear |
| Alan I Green, E Sherwood Brow. Comorbid schizophrenia and substance abuse. The Journal of clinical psychiatry. vol 67. issue 9. 2007-02-23. PMID:17081075. |
a brief discussion about the neurobiology of schizophrenia explains how schizophrenia may create a biologic predisposition to substance abuse by altering the brain reward system. |
2007-02-23 |
2023-08-12 |
Not clear |
| Georg Juckel, Florian Schlagenhauf, Michael Koslowski, Dimitri Filonov, Torsten Wüstenberg, Arno Villringer, Brian Knutson, Thorsten Kienast, Jürgen Gallinat, Jana Wrase, Andreas Hein. Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics. Psychopharmacology. vol 187. issue 2. 2006-12-22. PMID:16721614. |
dysfunction of the dopaminergic reward system may contribute to negative symptoms in schizophrenia. |
2006-12-22 |
2023-08-12 |
Not clear |
| Igor Elman, David Borsook, Scott E Luka. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16541087. |
food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. |
2006-11-01 |
2023-08-12 |
Not clear |
| Igor Elman, David Borsook, Scott E Luka. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 10. 2006-11-01. PMID:16541087. |
here, we propose a mechanism based on brain reward function, a relevant etiologic factor in both schizophrenia and overeating. |
2006-11-01 |
2023-08-12 |
Not clear |
| Cecilia Gotti, Michele Zoli, Francesco Clement. Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends in pharmacological sciences. vol 27. issue 9. 2006-10-26. PMID:16876883. |
these channels are involved both in physiological functions (including cognition, reward, motor activity and analgesia) and in pathological conditions such as alzheimer's disease, parkinson's disease, some forms of epilepsy, depression, autism and schizophrenia. |
2006-10-26 |
2023-08-12 |
Not clear |
| Alan I Gree. Treatment of schizophrenia and comorbid substance abuse: pharmacologic approaches. The Journal of clinical psychiatry. vol 67 Suppl 7. 2006-09-19. PMID:16961422. |
our group and others have advanced a neurobiological hypothesis to explain this comorbidity-that a mesocorticolimbic brain reward circuit underlies the substance use disorder in patients with schizophrenia. |
2006-09-19 |
2023-08-12 |
Not clear |
| Andrew Smith, Ming Li, Sue Becker, Shitij Kapu. Dopamine, prediction error and associative learning: a model-based account. Network (Bristol, England). vol 17. issue 1. 2006-06-28. PMID:16613795. |
our departure from model-free reinforcement learning also offers: 1) a parsimonious distinction between tonic and phasic dopamine functions; 2) a potential generalization of the role of phasic dopamine from valence-dependent "reward" processing to valence-independent "salience" processing; 3) an explanation for the selectivity of certain dopamine manipulations on motivation for distal rewards; and 4) a plausible link between formal notions of prediction error and accounts of disturbances of thought in schizophrenia (in which dopamine dysfunction is strongly implicated). |
2006-06-28 |
2023-08-12 |
Not clear |