| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A George Awa. Is it time to consider comorbid substance abuse as a new indication for antipsychotic drug development? Journal of psychopharmacology (Oxford, England). vol 26. issue 7. 2012-10-22. PMID:22170735. |
abnormalities in hippocampal/cortical function in schizophrenia which mediate reward and reinforcement behavior are identified as central to the development and maintenance of comorbid addictive states. |
2012-10-22 |
2023-08-12 |
Not clear |
| Joëlle Desfossés, Emmanuel Stip, Lahcen Ait Bentaleb, Olivier Lipp, Jean-Pierre Chiasson, Alexandra Furtos, Karine Venne, Edouard Kouassi, Stéphane Potvi. Plasma Endocannabinoid Alterations in Individuals with Substance Use Disorder are Dependent on the "Mirror Effect" of Schizophrenia. Frontiers in psychiatry. vol 3. 2012-10-12. PMID:23055987. |
theoretically, schizophrenia and sud may share endocannabinoid alterations in the brain reward system. |
2012-10-12 |
2023-08-12 |
Not clear |
| Daniel H Wolf, Raphaelt Gerraty, Theodore D Satterthwaite, James Loughead, Timothy Campellone, Mark A Elliott, Bruce I Turetsky, Ruben C Gur, Raquel E Gu. Striatal intrinsic reinforcement signals during recognition memory: relationship to response bias and dysregulation in schizophrenia. Frontiers in behavioral neuroscience. vol 5. 2012-10-02. PMID:22355285. |
these findings highlight the importance of accounting for intrinsic motivation and reward when studying cognitive tasks, and add to growing evidence of reward circuit dysfunction in schizophrenia that may impact cognition and function. |
2012-10-02 |
2023-08-12 |
human |
| Ryan D Ward, Eleanor H Simpson, Vanessa L Richards, Gita Deo, Kathleen Taylor, John I Glendinning, Eric R Kandel, Peter D Balsa. Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414818. |
dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. |
2012-09-21 |
2023-08-12 |
mouse |
| Ryan D Ward, Eleanor H Simpson, Vanessa L Richards, Gita Deo, Kathleen Taylor, John I Glendinning, Eric R Kandel, Peter D Balsa. Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 7. 2012-09-21. PMID:22414818. |
these results demonstrate for the first time in a transgenic animal model of schizophrenia a dissociation between hedonic reaction to reward and incentive motivation, and show a striking parallel to the proposed neurobiological and psychological mechanisms of impaired incentive motivation in schizophrenia. |
2012-09-21 |
2023-08-12 |
mouse |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
reward processing abnormalities have been implicated in the pathophysiology of negative symptoms such as anhedonia and avolition in schizophrenia. |
2012-09-10 |
2023-08-12 |
human |
| Mette Ødegaard Nielsen, Egill Rostrup, Sanne Wulff, Nikolaj Bak, Henrik Lublin, Shitij Kapur, Birte Glenthø. Alterations of the brain reward system in antipsychotic naïve schizophrenia patients. Biological psychiatry. vol 71. issue 10. 2012-08-28. PMID:22418013. |
alterations of the brain reward system in antipsychotic naïve schizophrenia patients. |
2012-08-28 |
2023-08-12 |
Not clear |
| Mette Ødegaard Nielsen, Egill Rostrup, Sanne Wulff, Nikolaj Bak, Henrik Lublin, Shitij Kapur, Birte Glenthø. Alterations of the brain reward system in antipsychotic naïve schizophrenia patients. Biological psychiatry. vol 71. issue 10. 2012-08-28. PMID:22418013. |
several studies have found alterations in the reward processing in patients with schizophrenia; however, most previous findings might be confounded by medication effects. |
2012-08-28 |
2023-08-12 |
Not clear |
| Alex S Cohen, Dallas A Callaway, Gina M Najolia, Jeff T Larsen, Gregory P Straus. On "risk" and reward: investigating state anhedonia in psychometrically defined schizotypy and schizophrenia. Journal of abnormal psychology. vol 121. issue 2. 2012-08-06. PMID:22149913. |
on "risk" and reward: investigating state anhedonia in psychometrically defined schizotypy and schizophrenia. |
2012-08-06 |
2023-08-12 |
Not clear |
| Christopher G Ahnallen, Gabrielle I Liverant, Kristin L Gregor, Barbara W Kamholz, James J Levitt, Suzy Bird Gulliver, Diego A Pizzagalli, Vamsi K Koneru, Gary B Kapla. The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia. Psychiatry research. vol 196. issue 1. 2012-07-24. PMID:22342123. |
these findings emphasize the importance of targeting reward system functioning in smoking cessation treatment for individuals with schizophrenia. |
2012-07-24 |
2023-08-12 |
Not clear |
| Gordon L F Cheng, Joey C Y Tang, Frendi W S Li, Esther Y Y Lau, Tatia M C Le. Schizophrenia and risk-taking: impaired reward but preserved punishment processing. Schizophrenia research. vol 136. issue 1-3. 2012-07-13. PMID:22285654. |
schizophrenia and risk-taking: impaired reward but preserved punishment processing. |
2012-07-13 |
2023-08-12 |
Not clear |
| Jouko Miettunen, Anu Raevuor. A meta-analysis of temperament in axis I psychiatric disorders. Comprehensive psychiatry. vol 53. issue 2. 2012-06-04. PMID:21565334. |
however, in pairwise comparisons, notable differences also in other dimensions emerged: in novelty seeking, the lowest scores were in social phobia (d = -0.87) and the highest in bulimia nervosa (d = 0.33); in reward dependence, the lowest scores were in schizophrenia (d = -0.36) and the highest in social phobia (d = 0.12); and in persistence, the lowest scores were in social phobia (d = -0.30) and the highest in anorexia nervosa (d = 0.49). |
2012-06-04 |
2023-08-12 |
Not clear |
| David T Chau, Jayme Ahmed, Thomas T Wang, Haiyi Xie, Ree Dawson, Alan I Gree. Raclopride lessens the ability of clozapine to suppress alcohol drinking in Syrian golden hamsters. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21619888. |
we have proposed that clozapine, through its weak da d2 receptor blocking action, coupled with its ability to potentiate noradrenergic and serotonergic activity, may ameliorate a dysfunction in the mesocorticolimbic da reward circuitry that underlies alcohol use disorder in patients with schizophrenia. |
2012-05-25 |
2023-08-12 |
Not clear |
| Anne-Marie Bédard, Jérôme Maheux, Daniel Lévesque, Anne-Noël Samah. Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 6. 2012-02-09. PMID:21326191. |
by enhancing the ability of reward cues to control behavior and by intensifying dopamine-mediated striatopallidal and striatonigral cell activity, standard (ie, continuous) antipsychotic treatment regimens might exacerbate drug-seeking and drug-taking behavior in schizophrenia. |
2012-02-09 |
2023-08-12 |
rat |
| James MacKillop, Jennifer W Tide. Cigarette demand and delayed reward discounting in nicotine-dependent individuals with schizophrenia and controls: an initial study. Psychopharmacology. vol 216. issue 1. 2011-11-08. PMID:21327760. |
cigarette demand and delayed reward discounting in nicotine-dependent individuals with schizophrenia and controls: an initial study. |
2011-11-08 |
2023-08-12 |
Not clear |
| Jessy John, Rohit Manchand. Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences. vol 36. issue 2. 2011-10-07. PMID:21654085. |
the nucleus accumbens (nac), a critical structure of the brain reward circuit, is implicated in normal goal-directed behaviour and learning as well as pathological conditions like schizophrenia and addiction. |
2011-10-07 |
2023-08-12 |
Not clear |
| Erin A Heerey, Tatyana M Matveeva, James M Gol. Imagining the future: degraded representations of future rewards and events in schizophrenia. Journal of abnormal psychology. vol 120. issue 2. 2011-09-12. PMID:21171727. |
we compared the performance of participants with schizophrenia (n = 39) and healthy participants (n = 25) on tasks measuring reward discounting and future event representations. |
2011-09-12 |
2023-08-12 |
human |
| Henry H Holcomb, Laura M Rowlan. How schizophrenia and depression disrupt reward circuitry. Current treatment options in neurology. vol 9. issue 5. 2011-07-14. PMID:17716599. |
how schizophrenia and depression disrupt reward circuitry. |
2011-07-14 |
2023-08-12 |
Not clear |
| Henry H Holcomb, Laura M Rowlan. How schizophrenia and depression disrupt reward circuitry. Current treatment options in neurology. vol 9. issue 5. 2011-07-14. PMID:17716599. |
other neuropsychiatric disorders such as schizophrenia and depression may provide models of disturbed reward biology that may prove useful when thinking about altered reward circuitry and behavior in pd and other neurological disorders. |
2011-07-14 |
2023-08-12 |
Not clear |
| Yang Tae Kim, Kyoung-Uk Lee, Seung Jae Le. Deficit in decision-making in chronic, stable schizophrenia: from a reward and punishment perspective. Psychiatry investigation. vol 6. issue 1. 2011-07-14. PMID:20046370. |
deficit in decision-making in chronic, stable schizophrenia: from a reward and punishment perspective. |
2011-07-14 |
2023-08-12 |
human |