| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcella Vacca, Kumar Parijat Tripathi, Luisa Speranza, Riccardo Aiese Cigliano, Francesco Scalabrì, Federico Marracino, Michele Madonna, Walter Sanseverino, Carla Perrone-Capano, Mario Rosario Guarracino, Maurizio D'Esposit. Effects of Mecp2 loss of function in embryonic cortical neurons: a bioinformatics strategy to sort out non-neuronal cells variability from transcriptome profiling. BMC bioinformatics. vol 17 Suppl 2. 2016-09-14. PMID:26821710. |
mecp2 null mice model rett syndrome (rtt) a human neurological disorder affecting females after apparent normal pre- and peri-natal developmental periods. |
2016-09-14 |
2023-08-13 |
mouse |
| Aparna A Bhanushali, A Mandsaurwala, Bibhu R Da. Homozygous c.1160C>T (P38L) in the MECP2 gene in a female Rett syndrome patient. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 25. 2016-09-13. PMID:26755454. |
homozygous c.1160c>t (p38l) in the mecp2 gene in a female rett syndrome patient. |
2016-09-13 |
2023-08-13 |
Not clear |
| Aparna A Bhanushali, A Mandsaurwala, Bibhu R Da. Homozygous c.1160C>T (P38L) in the MECP2 gene in a female Rett syndrome patient. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 25. 2016-09-13. PMID:26755454. |
mutations in the mecp2 gene on chromosome xq28 have been shown to be the cause of rett syndrome. |
2016-09-13 |
2023-08-13 |
Not clear |
| Aparna A Bhanushali, A Mandsaurwala, Bibhu R Da. Homozygous c.1160C>T (P38L) in the MECP2 gene in a female Rett syndrome patient. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 25. 2016-09-13. PMID:26755454. |
sequencing of the mecp2 gene in a patient with clinical suspicion of rett syndrome revealed c.1160c>t (p387l) in exon 4 of the mecp2 gene homozygously. |
2016-09-13 |
2023-08-13 |
Not clear |
| Aparna A Bhanushali, A Mandsaurwala, Bibhu R Da. Homozygous c.1160C>T (P38L) in the MECP2 gene in a female Rett syndrome patient. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 25. 2016-09-13. PMID:26755454. |
females with rett syndrome are usually heterozygous for a mutation in mecp2. |
2016-09-13 |
2023-08-13 |
Not clear |
| Carlos Bueno, Rafael Tabares-Seisdedos, Jose M Moraleda, Salvador Martine. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PloS one. vol 11. issue 4. 2016-08-25. PMID:27064487. |
rett syndrome mutant neural cells lacks mecp2 immunoreactive bands. |
2016-08-25 |
2023-08-13 |
Not clear |
| Carlos Bueno, Rafael Tabares-Seisdedos, Jose M Moraleda, Salvador Martine. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PloS one. vol 11. issue 4. 2016-08-25. PMID:27064487. |
dysfunctions of mecp2 protein lead to various neurological disorders such as rett syndrome and autism. |
2016-08-25 |
2023-08-13 |
Not clear |
| Carlos Bueno, Rafael Tabares-Seisdedos, Jose M Moraleda, Salvador Martine. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PloS one. vol 11. issue 4. 2016-08-25. PMID:27064487. |
some researchers suggest that multiple mecp2 immunoreactive bands are unidentified proteins that cross-react with the mecp2 antibody or degradation product of mecp2, while others suggest that mecp2 post-transcriptional processing generates multiple molecular forms linked to cell signaling, but so far they have not been properly analyzed in relation to rett syndrome experimental models. |
2016-08-25 |
2023-08-13 |
Not clear |
| Carlos Bueno, Rafael Tabares-Seisdedos, Jose M Moraleda, Salvador Martine. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PloS one. vol 11. issue 4. 2016-08-25. PMID:27064487. |
our results clearly indicate that mecp2 antibodies have no cross-reactivity with similar epitopes on others proteins, supporting the idea that mecp2 may exist in multiple different molecular forms and that molecular pattern variations derived from altered post-transcriptional processing may underlay rett syndrome physiophatology. |
2016-08-25 |
2023-08-13 |
Not clear |
| Clementina Cobolli Gigli, Linda Scaramuzza, Anna Gandaglia, Elisa Bellini, Marina Gabaglio, Daniela Parolaro, Charlotte Kilstrup-Nielsen, Nicoletta Landsberger, Francesco Bedogn. MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background. PloS one. vol 11. issue 4. 2016-08-25. PMID:27097329. |
mecp2 mutations cause a number of neurological disorders of which rett syndrome (rtt) represents the most thoroughly analysed condition. |
2016-08-25 |
2023-08-13 |
mouse |
| Lucia Ciccoli, Claudio De Felice, Silvia Leoncini, Cinzia Signorini, Alessio Cortelazzo, Gloria Zollo, Alessandra Pecorelli, Marcello Rossi, Joussef Haye. Red blood cells in Rett syndrome: oxidative stress, morphological changes and altered membrane organization. Biological chemistry. vol 396. issue 11. 2016-08-17. PMID:26040005. |
in particular, we focus on morphological changes, membrane oxidative damage, altered membrane fatty acid profile, and aberrant skeletal organization in erythrocytes from patients with typical rett syndrome and mecp2 gene mutations. |
2016-08-17 |
2023-08-13 |
Not clear |
| Wei Li, Xin Xu, Lucas Pozzo-Mille. Excitatory synapses are stronger in the hippocampus of Rett syndrome mice due to altered synaptic trafficking of AMPA-type glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 11. 2016-08-12. PMID:26929363. |
using the methyl-cpg-binding protein 2 (mecp2) knockout (ko) mouse model of rett syndrome, we show that naïve excitatory synapses onto hippocampal pyramidal neurons of symptomatic mice have all of the hallmarks of potentiated synapses. |
2016-08-12 |
2023-08-13 |
mouse |
| Marwa Kharrat, Ines Hsairi, Nourhene Fendri-Kriaa, Houda Kenoun, Houda Ben Othmen, Afif Ben Mahmoud, Rania Ghorbel, Imen Abid, Chahnez Triki, Faiza Fakhfak. A Novel Mutation p.A59P in N-Terminal Domain of Methyl-CpG-Binding Protein 2 Confers Phenotypic Variability in 3 Cases of Tunisian Rett Patients: Clinical Evaluations and In Silico Investigations. Journal of child neurology. vol 30. issue 13. 2016-08-10. PMID:25862735. |
rett syndrome is a monogenic x-linked dominant neurodevelopmental disorder related to mutation in mecp2, which encodes the methyl-cpg-binding protein mecp2. |
2016-08-10 |
2023-08-13 |
Not clear |
| Annette Becker, Peng Zhang, Lena Allmann, Daniela Meilinger, Bianca Bertulat, Daniel Eck, Maria Hofstaetter, Giody Bartolomei, Michael O Hottiger, Valérie Schreiber, Heinrich Leonhardt, M Cristina Cardos. Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure. The Journal of biological chemistry. vol 291. issue 10. 2016-08-03. PMID:26772194. |
we have shown previously that the mecp2 level increases during differentiation and that it causes large-scale chromatin reorganization, which is disturbed by mecp2 rett syndrome mutations. |
2016-08-03 |
2023-08-13 |
mouse |
| K Griesi-Oliveira, A Acab, A R Gupta, D Y Sunaga, T Chailangkarn, X Nicol, Y Nunez, M F Walker, J D Murdoch, S J Sanders, T V Fernandez, W Ji, R P Lifton, E Vadasz, A Dietrich, D Pradhan, H Song, G-L Ming, X Gu, G Haddad, M C N Marchetto, N Spitzer, M R Passos-Bueno, M W State, A R Muotr. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Molecular psychiatry. vol 20. issue 11. 2016-08-02. PMID:25385366. |
mutations in mecp2 cause rett syndrome, revealing common pathways among asds. |
2016-08-02 |
2023-08-13 |
mouse |
| Cinzia Signorini, Claudio De Felice, Silvia Leoncini, Rikke S Møller, Gloria Zollo, Sabrina Buoni, Alessio Cortelazzo, Roberto Guerranti, Thierry Durand, Lucia Ciccoli, Maurizio D'Esposito, Kirstine Ravn, Joussef Haye. MECP2 Duplication Syndrome: Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome. PloS one. vol 11. issue 3. 2016-07-26. PMID:26930212. |
rett syndrome (rtt) and mecp2 duplication syndrome (mds) are neurodevelopmental disorders caused by alterations in the methyl-cpg binding protein 2 (mecp2) gene expression. |
2016-07-26 |
2023-08-13 |
human |
| Stefania Filosa, Alessandra Pecorelli, Maurizio D'Esposito, Giuseppe Valacchi, Joussef Haje. Exploring the possible link between MeCP2 and oxidative stress in Rett syndrome. Free radical biology & medicine. vol 88. issue Pt A. 2016-07-22. PMID:25960047. |
exploring the possible link between mecp2 and oxidative stress in rett syndrome. |
2016-07-22 |
2023-08-13 |
mouse |
| Jenny Downs, Michelle Stahlhut, Kingsley Wong, Birgit Syhler, Anne-Marie Bisgaard, Peter Jacoby, Helen Leonar. Validating the Rett Syndrome Gross Motor Scale. PloS one. vol 11. issue 1. 2016-07-19. PMID:26800272. |
rett syndrome is a pervasive neurodevelopmental disorder associated with a pathogenic mutation on the mecp2 gene. |
2016-07-19 |
2023-08-13 |
Not clear |
| Keita Tsujimura, Koichiro Irie, Hideyuki Nakashima, Yoshihiro Egashira, Yoichiro Fukao, Masayuki Fujiwara, Masayuki Itoh, Masahiro Uesaka, Takuya Imamura, Yasukazu Nakahata, Yui Yamashita, Takaya Abe, Shigeo Takamori, Kinichi Nakashim. miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes. Cell reports. vol 12. issue 11. 2016-07-06. PMID:26344767. |
mir-199a links mecp2 with mtor signaling and its dysregulation leads to rett syndrome phenotypes. |
2016-07-06 |
2023-08-13 |
mouse |
| Keita Tsujimura, Koichiro Irie, Hideyuki Nakashima, Yoshihiro Egashira, Yoichiro Fukao, Masayuki Fujiwara, Masayuki Itoh, Masahiro Uesaka, Takuya Imamura, Yasukazu Nakahata, Yui Yamashita, Takaya Abe, Shigeo Takamori, Kinichi Nakashim. miR-199a Links MeCP2 with mTOR Signaling and Its Dysregulation Leads to Rett Syndrome Phenotypes. Cell reports. vol 12. issue 11. 2016-07-06. PMID:26344767. |
rett syndrome (rtt) is a neurodevelopmental disorder caused by mecp2 mutations. |
2016-07-06 |
2023-08-13 |
mouse |