| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christoph Niemietz, Lutz Fleischhauer, Vanessa Sandfort, Sarah Guttmann, Andree Zibert, Hartmut H-J Schmid. Hepatocyte-like cells reveal novel role of SERPINA1 in transthyretin amyloidosis. Journal of cell science. vol 131. issue 23. 2019-12-03. PMID:30333144. |
transthyretin (ttr)-related familial amyloid polyneuropathy (attr) results from aggregation and extracellular disposition of misfolded ttr mutants. |
2019-12-03 |
2023-08-13 |
Not clear |
| Diletta Ami, Paolo Mereghetti, Manuela Leri, Sofia Giorgetti, Antonino Natalello, Silvia Maria Doglia, Massimo Stefani, Monica Bucciantin. A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:30131519. |
the presence of extracellular deposits of amyloid aggregates of wt or l55p ttr, respectively, is a key hallmark of two pathological conditions, known as senile systemic amyloidosis and familial amyloid polyneuropathy. |
2019-10-25 |
2023-08-13 |
human |
| Yukimoto Tsuda, Kunitoshi Yamanaka, Risa Toyoshima, Mitsuharu Ueda, Teruaki Masuda, Yohei Misumi, Teru Ogura, Yukio And. Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening. Scientific reports. vol 8. issue 1. 2019-10-22. PMID:30552363. |
familial amyloid polyneuropathy is a hereditary systemic amyloidosis caused by a mutation in the transthyretin (ttr) gene. |
2019-10-22 |
2023-08-13 |
human |
| Estefania P Azevedo, Anderson B Guimaraes-Costa, Christianne Bandeira-Melo, Leila Chimelli, Marcia Waddington-Cruz, Elvira M Saraiva, Fernando L Palhano, Debora Fogue. Inflammatory profiling of patients with familial amyloid polyneuropathy. BMC neurology. vol 19. issue 1. 2019-08-21. PMID:31253122. |
familial amyloid polyneuropathy (fap) or attrv (amyloid ttr variant) amyloidosis is a fatal hereditary disease characterized by the deposition of amyloid fibrils composed of transthyretin (ttr). |
2019-08-21 |
2023-08-13 |
Not clear |
| Roger Pero-Gascon, Laura Pont, Victoria Sanz-Nebot, Fernando Benavent. On-Line Immunoaffinity Solid-Phase Extraction Capillary Electrophoresis-Mass Spectrometry for the Analysis of Serum Transthyretin. Methods in molecular biology (Clifton, N.J.). vol 1972. 2019-08-07. PMID:30847784. |
ttr is a protein biomarker related to diverse types of amyloidosis, such as familial amyloidotic polyneuropathy type i (fap-i), which is the most common hereditary systemic amyloidosis. |
2019-08-07 |
2023-08-13 |
Not clear |
| Yvette N Lamb, Emma D Deek. Tafamidis: A Review in Transthyretin Amyloidosis with Polyneuropathy. Drugs. vol 79. issue 8. 2019-07-23. PMID:31098895. |
transthyretin amyloidosis with polyneuropathy (attr-pn), a rare and progressive hereditary disorder, results from mutations in the gene coding for the transthyretin (ttr) protein that destabilize the protein's tetrameric structure. |
2019-07-23 |
2023-08-13 |
Not clear |
| Jean-Pascal Lefaucheur, Hela G Zouari, Farida Gorram, Tarik Nordine, Thibaud Damy, Violaine Planté-Bordeneuv. The value of electrochemical skin conductance measurement using Sudoscan® in the assessment of patients with familial amyloid polyneuropathy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 129. issue 8. 2019-06-26. PMID:29883834. |
to reappraise the value of electrochemical skin conductance (esc) measurement by sudoscan® to assess the distal involvement of small autonomic fibers in familial amyloid polyneuropathy (fap) due to various transthyretin (ttr) mutations. |
2019-06-26 |
2023-08-13 |
Not clear |
| Natália Novais Ferreira, David Afonso Cunha Dias, Rui Pedro Afonso Carvalho, Maria Teresa Pardal Monteiro Coelh. RE-INTERVENTION IN DE NOVO VITREOUS OPACITIES AFTER PARS PLANA VITRECTOMY IN FAMILIAL AMYLOIDOTIC POLYNEUROPATHY TTR VAL30METPORTUGUESE PATIENTS. Retinal cases & brief reports. vol 13. issue 3. 2019-06-24. PMID:28333852. |
re-intervention in de novo vitreous opacities after pars plana vitrectomy in familial amyloidotic polyneuropathy ttr val30metportuguese patients. |
2019-06-24 |
2023-08-13 |
Not clear |
| H Y Lin, R P Da. [The ocular involvement in the transthyretin-related familial amyloid polyneuropathy]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. vol 53. issue 10. 2019-06-17. PMID:29050191. |
transthyretin (ttr)-related familial amyloid polyneuropathy (fap), which is caused by mutant ttr, is a rare but fatal autosomal dominant disease. |
2019-06-17 |
2023-08-13 |
Not clear |
| Iglika Yordanova, Zornitza Pavlova, Andrey Kirov, Tihomir Todorov, Assen Alexiev, Stayko Sarafov, Lyudmila Mateva, Teodora Chamova, Mariana Gospodinova, Vanyo Mitev, Ivailo Tournev, Albena Todorov. Monoallelic expression of the TTR gene as a contributor to the age at onset and penetrance of TTR-related amyloidosis. Gene. vol 705. 2019-06-10. PMID:30981840. |
ttr-related amyloidosis (attr) is manifested in two allelic forms: familial amyloid polyneuropathy (ttr-fap) and cardiomyopathy (ttr-fac), both caused by mutations in the ttr gene. |
2019-06-10 |
2023-08-13 |
Not clear |
| H G Zouari, S Ng Wing Tin, A Wahab, T Damy, J-P Lefaucheu. Assessment of autonomic innervation of the foot in familial amyloid polyneuropathy. European journal of neurology. vol 26. issue 1. 2019-06-03. PMID:30102818. |
distal involvement of autonomic nerve fibers is critical in familial amyloid polyneuropathy (fap) due to transthyretin (ttr) mutation. |
2019-06-03 |
2023-08-13 |
Not clear |
| Kuan Fan, Haixia Zhu, Hongbo Xu, Ping Mao, Lamei Yuan, Hao Den. The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis. Journal of neurology. vol 266. issue 1. 2019-05-07. PMID:30470998. |
familial amyloid polyneuropathies (faps) are life-threatening, autosomal dominant diseases resulting, in most instances, from transthyretin gene (ttr) variants. |
2019-05-07 |
2023-08-13 |
Not clear |
| Zenshi Miyake, Kiyotaka Nakamagoe, Naoki Ezawa, Tsuneaki Yoshinaga, Ryosuke Hashimoto, Taiki Sato, Yoshiki Sekijima, Akira Tamaok. Late-onset Transthyretin (TTR)-familial Amyloid Polyneuropathy (FAP) with a Long Disease Duration from Non-endemic Areas in Japan. Internal medicine (Tokyo, Japan). vol 58. issue 5. 2019-04-22. PMID:30333406. |
late-onset transthyretin (ttr)-familial amyloid polyneuropathy (fap) with a long disease duration from non-endemic areas in japan. |
2019-04-22 |
2023-08-13 |
Not clear |
| Zenshi Miyake, Kiyotaka Nakamagoe, Naoki Ezawa, Tsuneaki Yoshinaga, Ryosuke Hashimoto, Taiki Sato, Yoshiki Sekijima, Akira Tamaok. Late-onset Transthyretin (TTR)-familial Amyloid Polyneuropathy (FAP) with a Long Disease Duration from Non-endemic Areas in Japan. Internal medicine (Tokyo, Japan). vol 58. issue 5. 2019-04-22. PMID:30333406. |
we herein report the case of an 84-year-old woman with transthyretin (ttr) val30met-associated familial amyloid polyneuropathy (fap-attr val30met), representing a very old case. |
2019-04-22 |
2023-08-13 |
Not clear |
| Marina Grandis, Alessandro Geroldi, Rossella Gulli, Fiore Manganelli, Fabio Gotta, Merit Lamp, Paola Origone, Lucia Trevisan, Chiara Gemelli, Sabrina Fabbri, Angelo Schenone, Stefano Tozza, Lucio Santoro, Emilia Bellone, Paola Mandic. Autosomal-dominant transthyretin (TTR)-related amyloidosis is not a frequent CMT2 neuropathy "in disguise". Orphanet journal of rare diseases. vol 13. issue 1. 2019-04-16. PMID:30286783. |
transthyretin (ttr)-related familial amyloid polyneuropathy (ttr-fap) is a life-threatening autosomal dominant, systemic disease. |
2019-04-16 |
2023-08-13 |
Not clear |
| Yuya Hayashi, Hirofumi Jon. Recent Advances in Oligonucleotide-Based Therapy for Transthyretin Amyloidosis: Clinical Impact and Future Prospects. Biological & pharmaceutical bulletin. vol 41. issue 12. 2019-03-27. PMID:30504675. |
transthyretin (ttr) amyloidosis, also known as transthyretin-related familial amyloidotic polyneuropathy (attr-fap), is a fatal hereditary systemic amyloidosis caused by mutant forms of ttr. |
2019-03-27 |
2023-08-13 |
Not clear |
| Cecilia Monteiro, Ana Martins da Silva, Natália Ferreira, Jaleh Mesgarzadeh, Marta Novais, Teresa Coelho, Jeffery W Kell. Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 25. issue 2. 2019-03-11. PMID:29993288. |
hereditary transthyretin (ttr) amyloidosis associated with the ttrv30m (p.ttrv50m) mutation presents predominantly as an axonal polyneuropathy, with variable involvement of other organs. |
2019-03-11 |
2023-08-13 |
Not clear |
| Mitsuharu Ueda, Taro Yamashita, Yohei Misumi, Teruaki Masuda, Yukio And. Origin of sporadic late-onset hereditary ATTR Val30Met amyloidosis in Japan. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. vol 25. issue 3. 2019-03-11. PMID:30486687. |
hereditary transthyretin (attrm) amyloidosis, formerly known as familial amyloid polyneuropathy, is a major type of hereditary systemic amyloidosis, in which the disease is caused by mutant transthyretin (ttr). |
2019-03-11 |
2023-08-13 |
Not clear |
| Amir Jahic, Andrea Bock, Franz Duca, Diana Bonderman, Julia Mascherbauer, Reinhard Windhager, Michaela Auer-Grumbach, Christian Beet. Development and validation of a TTR-specific copy number screening tool, and application to potentially relevant patient cohorts. Molecular and cellular probes. vol 41. 2019-03-08. PMID:30142390. |
subsequent application to 13 patients diagnosed with attrwt, and to 93 patients presenting with late onset and presumably inherited polyneuropathy did not identify ttr cnvs. |
2019-03-08 |
2023-08-13 |
Not clear |
| Xiangshun Li, Yanyi Lyu, Jingling Shen, Yanshuang Mu, Lixia Qiang, Li Liu, Kimi Araki, Bruno P Imbimbo, Ken-Ichi Yamamura, Shoude Jin, Zhenghua L. Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci. Laboratory investigation; a journal of technical methods and pathology. vol 98. issue 4. 2019-03-05. PMID:29330472. |
familial amyloidotic polyneuropathy is an autosomal dominant disorder caused by a point mutation in the transthyretin (ttr) gene. |
2019-03-05 |
2023-08-13 |
mouse |