| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianghong Kuang, Wenhui Hu, Mingshan Yan, Paul K Y Won. Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected mice. Neurochemistry international. vol 57. issue 7. 2011-09-07. PMID:20813146. |
in infected mice treated with pba we also noted a reduction in the severity of the neuropathology in brainstem tissues and a delayed onset of paralysis. |
2011-09-07 |
2023-08-12 |
mouse |
| Lili C Kudo, Liubov Parfenova, Guijie Ren, Nancy Vi, Maria Hui, Zhongcai Ma, Kimbley Lau, Michelle Gray, Fawzia Bardag-Gorce, Martina Wiedau-Pazos, Koon-Sea Hui, Stanislav L Karste. Puromycin-sensitive aminopeptidase (PSA/NPEPPS) impedes development of neuropathology in hPSA/TAU(P301L) double-transgenic mice. Human molecular genetics. vol 20. issue 9. 2011-08-15. PMID:21320871. |
double-transgenic animals for hpsa and tau(p301l) transgenes demonstrated a distinct trend for delayed paralysis and showed significantly improved motor neuron counts, no gliosis and markedly reduced levels of total and hyperphosphorylated tau in the spinal cord, brain stem, cortex, hippocampus and cerebellum of adult and aged animals when compared with tau(p301l) mice. |
2011-08-15 |
2023-08-12 |
mouse |
| Katherine C Murray, Marilee J Stephens, Edmund W Ballou, Charles J Heckman, David J Bennet. Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. Journal of neurophysiology. vol 105. issue 2. 2011-06-16. PMID:20980537. |
immediately after spinal cord injury (sci), a devastating paralysis results from the loss of brain stem and cortical innervation of spinal neurons that control movement, including a loss of serotonergic (5-ht) innervation of motoneurons. |
2011-06-16 |
2023-08-12 |
rat |
| G A Koroleva, A N Lukashev, L V Khudiakova, A N Mustafina, V A Lashkevic. [Encephalomyelitis caused by enterovirus type 71 in children]. Voprosy virusologii. vol 55. issue 6. 2011-03-21. PMID:21381332. |
in a small percentage of infants (aged 6 months to 3 years), hfmd was accompanied by acute neurological complications, such as serous meningitis, poliomyelitis-like syndrome (extremity pareses and muscle paralyses); brain stem encephalitis (myoclonic jerks, tremor, lethargy, swallowing and speech disorders, cardiopulmonary failure, pulmonary edema, shock, coma, death). |
2011-03-21 |
2023-08-12 |
Not clear |
| S Schmalbach, S Petr. Histone deacetylation and motor neuron degeneration. CNS & neurological disorders drug targets. vol 9. issue 3. 2010-12-21. PMID:20406183. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease with progressive muscular wasting and paralysis due to loss of motor neurons in the primary motor cortex, brainstem and spinal cord. |
2010-12-21 |
2023-08-12 |
Not clear |
| Celeste M Karch, David R Borchel. An examination of alpha B-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis. Journal of neurochemistry. vol 113. issue 5. 2010-07-08. PMID:20067574. |
transgenic mice that over-express mutant sod1 develop paralysis and accumulate aggregates of mutant protein in the brainstem and spinal cord. |
2010-07-08 |
2023-08-12 |
mouse |
| Shih-Min Wang, Ching-Chuan Li. Enterovirus 71: epidemiology, pathogenesis and management. Expert review of anti-infective therapy. vol 7. issue 6. 2009-10-26. PMID:19681701. |
most ev71 infections commonly result in hand-foot-mouth disease or herpangina, and some cases are associated with brainstem encephalitis and acute flaccid paralysis. |
2009-10-26 |
2023-08-12 |
Not clear |
| b' L Tolosa, M Mir, G Olmos, J Llad\\xc3\\xb. Vascular endothelial growth factor protects motoneurons from serum deprivation-induced cell death through phosphatidylinositol 3-kinase-mediated p38 mitogen-activated protein kinase inhibition. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19041930.' |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective degeneration and death of motoneurons in the spinal cord, brainstem and motor cortex which causes progressive muscle weakness and paralysis. |
2009-05-20 |
2023-08-12 |
rat |
| Lokesh C Wijesekera, P Nigel Leig. Amyotrophic lateral sclerosis. Orphanet journal of rare diseases. vol 4. 2009-05-05. PMID:19192301. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. |
2009-05-05 |
2023-08-12 |
Not clear |
| Shih-Min Wang, Tzong-Shiann Ho, Ching-Fen Shen, Ching-Chuan Li. Enterovirus 71, one virus and many stories. Pediatrics and neonatology. vol 49. issue 4. 2009-01-14. PMID:19054915. |
enterovirus 71 (ev71) has emerged as a significant cause of brainstem encephalitis and acute flaccid paralysis in taiwan. |
2009-01-14 |
2023-08-12 |
Not clear |
| Yoshihiko Imamura, Yoshinao Fujikawa, Hirofumi Komaki, Eiji Nakagawa, Kenji Sugai, Noriko Sato, Masayuki Sasak. [A case of Möbius syndrome presenting with symptoms of severe infantile form of congenital muscular disorder]. No to hattatsu = Brain and development. vol 39. issue 1. 2007-02-23. PMID:17228821. |
we propose that a thin slice mri should be obtained to observe the cranial nerves around the brain stem if patients show symptoms of congenital myopathy or congenital myotonic dystrophy as well as facial nerve and other cranial nerve paralyses. |
2007-02-23 |
2023-08-12 |
Not clear |
| M F Abdul-Careem, B D Hunter, A J Sarson, A Mayameei, H Zhou, S Shari. Marek's disease virus-induced transient paralysis is associated with cytokine gene expression in the nervous system. Viral immunology. vol 19. issue 2. 2006-09-28. PMID:16817759. |
), neck and limb paralysis was observed in 18% of infected chickens, which was associated with various degrees of edema, vacuolation, perivascular cuffing of mononuclear cells, and glial cell infiltration mainly in the cerebrum, cerebellum, and brain stem. |
2006-09-28 |
2023-08-12 |
Not clear |
| Raymond F Burk, Joani M Christensen, Mark J Maguire, Lori M Austin, William O Whetsell, James M May, Kristina E Hill, Ford F Ebne. A combined deficiency of vitamins E and C causes severe central nervous system damage in guinea pigs. The Journal of nutrition. vol 136. issue 6. 2006-06-22. PMID:16702324. |
these results indicate that the paralysis and death caused by combined deficiency of vitamins e and c in guinea pigs is caused by severe damage in the brainstem and spinal cord. |
2006-06-22 |
2023-08-12 |
Not clear |
| A N Patitucci, M R Alley, B R Jones, W A Charlesto. Protozoal encephalomyelitis of dogs involving Neospora caninum and Toxoplasma gondii in New Zealand. New Zealand veterinary journal. vol 45. issue 6. 2005-09-27. PMID:16031995. |
all cases of neosporosis showed ataxia and progressive hind limb paralysis due to multifocal non-suppurative meningoencephalomyelitis which was most severe in the spinal cord and base of the brain stem. |
2005-09-27 |
2023-08-12 |
cattle |
| C Pierrot-Deseillign. [From the abducens nucleus to spatial memory: an ocular motor journey]. Revue neurologique. vol 161. issue 5. 2005-09-08. PMID:16106806. |
the main brainstem syndromes involving vertical eye movements are also reviewed: in particular, the third nerve nucleus syndrome, in which both ipsilateral third nerve paralysis and contralateral superior rectus paralysis (with hypotropia) result from a unilateral third nerve nucleus lesion. |
2005-09-08 |
2023-08-12 |
Not clear |
| R Schiffte. [The suffering of Heinrich Heine]. Fortschritte der Neurologie-Psychiatrie. vol 73. issue 1. 2005-03-09. PMID:15666222. |
the symptoms which recurred over 25 years include multiple severe paralysis of cranial nerves, dramatic radicular neuralgias and radicular paralysis in addition to a partial transverse lesion of the spinal cord and terminal coughing and regurgation fits in the absence of symptoms in the cerebrum and brain stem, these symptoms hardly permit different diagnosis. |
2005-03-09 |
2023-08-12 |
Not clear |
| Samuel L Murphy, Marek J Honczarenko, Natalie V Dugger, Paul M Hoffman, Glen N Gaulto. Disparate regions of envelope protein regulate syncytium formation versus spongiform encephalopathy in neurological disease induced by murine leukemia virus TR. Journal of virology. vol 78. issue 15. 2004-08-06. PMID:15254211. |
virus cloned from this selection, termed trm, induced progressive neurological disease characterized by ataxia and paralysis and the appearance of spongiform neurodegeneration throughout the brain stem and spinal cord. |
2004-08-06 |
2023-08-12 |
human |
| Fatma Mujgan Sonmez, Ender Odemis, Ali Ahmetoglu, Adnan Ayva. Brainstem encephalitis and acute disseminated encephalomyelitis following mumps. Pediatric neurology. vol 30. issue 2. 2004-04-21. PMID:14984908. |
a previously healthy female, aged 4 years 3 months, developed brainstem encephalitis with clinical manifestations of fever, decreased level of consciousness, and left facial and abducens paralysis 1 week after bilateral parotitis. |
2004-04-21 |
2023-08-12 |
Not clear |
| J C V M Copray, D Jaarsma, B M Küst, R W G Bruggeman, I Mantingh, N Brouwer, H W G M Boddek. Expression of the low affinity neurotrophin receptor p75 in spinal motoneurons in a transgenic mouse model for amyotrophic lateral sclerosis. Neuroscience. vol 116. issue 3. 2003-05-07. PMID:12573711. |
amyotrophic lateral sclerosis is a lethal neurodegenerative disorder involving motoneuron loss in the cortex, brainstem and spinal cord, resulting in progressive paralysis. |
2003-05-07 |
2023-08-12 |
mouse |
| José León-Carrión, Philippe van Eeckhout, María Del Rosario Domínguez-Morales, Francisco Javier Pérez-Santamarí. The locked-in syndrome: a syndrome looking for a therapy. Brain injury. vol 16. issue 7. 2002-09-11. PMID:12119076. |
the locked-in syndrome (lis) is a very severe condition caused by a primary vascular or traumatic injury to the brainstem, normally corresponding to a ventral pons lesion due to an obstruction of the basilar artery, and characterized by upper motor neuron quadriplegia, paralysis of lower cranial nerves, bilateral paresis of horizontal gaze and anarthria, and with preserved consciousness. |
2002-09-11 |
2023-08-12 |
Not clear |