| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kevin Rostasy, Simone Mader, Kathrin Schanda, Peter Huppke, Jutta Gärtner, Verena Kraus, Michael Karenfort, Daniel Tibussek, Astrid Blaschek, Barbara Bajer-Kornek, Steffen Leitz, Mareike Schimmel, Franziska Di Pauli, Thomas Berger, Markus Reind. Anti-myelin oligodendrocyte glycoprotein antibodies in pediatric patients with optic neuritis. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22371853. |
to study the humoral immune response directed at myelin oligodendrocyte glycoprotein (mog)in pediatric patients with isolated and recurrent optic neuritis(on). |
2012-08-31 |
2023-08-12 |
Not clear |
| Katharina Hein, Ivana Gadjanski, Benedikt Kretzschmar, Katharina Lange, Ricarda Diem, Muriel B Sättler, Mathias Bäh. An optical coherence tomography study on degeneration of retinal nerve fiber layer in rats with autoimmune optic neuritis. Investigative ophthalmology & visual science. vol 53. issue 1. 2012-03-06. PMID:22131393. |
the aim of the present study was to evaluate the ability and accuracy of spectral domain optical coherence tomography (oct) for in vivo monitoring of retinal ganglion cell degeneration in a rat model of myelin oligodendrocyte glycoprotein-induced optic neuritis. |
2012-03-06 |
2023-08-12 |
rat |
| Christian R Rau, Katharina Hein, Muriel B Sättler, Benedikt Kretzschmar, Carina Hillgruber, Bradford L McRae, Ricarda Diem, Mathias Bäh. Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis. The American journal of pathology. vol 178. issue 4. 2011-07-15. PMID:21406175. |
to evaluate whether fty720 has neuroprotective properties, we tested this drug in a rat model of myelin oligodendrocyte glycoprotein-induced optic neuritis. |
2011-07-15 |
2023-08-12 |
rat |
| Xiaoli Guo, Chikako Harada, Kazuhiko Namekata, Kenji Kikushima, Yoshinori Mitamura, Hiroshi Yoshida, Yoh Matsumoto, Takayuki Harad. Effect of geranylgeranylacetone on optic neuritis in experimental autoimmune encephalomyelitis. Neuroscience letters. vol 462. issue 3. 2009-10-26. PMID:19616065. |
since it can cause irreversible visual loss, especially in the optic-spinal form of ms or neuromyelitis optica (nmo), the present study was conducted to assess the effects of geranylgeranylacetone (gga) on optic neuritis in the experimental autoimmune encephalomyelitis (eae) mouse model of ms. myelin oligodendrocyte glycoprotein-induced eae mice received oral administration of gga at 500 mg/kg or vehicle once daily for 22 days. |
2009-10-26 |
2023-08-12 |
mouse |
| Muriel B Sättler, Mauro Togni, Ivana Gadjanski, Kurt-Wolfram Sühs, Nadine Meyer, Mathias Bähr, Ricarda Die. Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis. Journal of neuroimmunology. vol 193. issue 1-2. 2008-03-04. PMID:18037506. |
we detected important differences in neurodegeneration in various subtypes of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2008-03-04 |
2023-08-12 |
rat |
| Martha E Stokely, Manzoor A Bhat, Peter Koule. Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. Journal of neuroscience methods. vol 166. issue 2. 2008-02-14. PMID:17719649. |
tissue microfluorimetry was used to measure seven established markers for human ms pathology in normal and autoimmune optic nerves 13 days after antigen exposure, in a brown norway rat model of myelin oligodendrocyte glycoprotein (mog) peptide (35-55)-induced autoimmune optic neuritis. |
2008-02-14 |
2023-08-12 |
human |
| Estelle Bettell. Building different mouse models for human MS. Annals of the New York Academy of Sciences. vol 1103. 2007-07-25. PMID:17376825. |
here, we summarize our published findings on two mouse models: 2d2 myelin oligodendrocyte glycoprotein (mog)-specific t cell receptor (tcr) transgenic mice, which develop spontaneous isolated optic neuritis, and 2d2 mice crossed with mog-specific igh knockin (th) mice, which spontaneously develop a severe form of experimental autoimmune encephalomyelitis (eae) with a selective distribution of meningeal and parenchymal inflammatory lesions in the spinal cord and optic nerves similar to that found in human devic's disease. |
2007-07-25 |
2023-08-12 |
mouse |
| Katharina Maier, Antje V Kuhnert, Naimeh Taheri, Muriel B Sättler, Maria K Storch, Sarah K Williams, Mathias Bähr, Ricarda Die. Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study. The American journal of pathology. vol 169. issue 4. 2006-11-24. PMID:17003491. |
after myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis became clinically manifest, optic neuritis was monitored by recording visual evoked potentials. |
2006-11-24 |
2023-08-12 |
human |
| Muriel B Sättler, Iris Demmer, Sarah K Williams, Katharina Maier, Doron Merkler, Ivana Gadjanski, Christine Stadelmann, Mathias Bähr, Ricarda Die. Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764858. |
we have characterized previously time course and mechanisms of neuronal apoptosis in a rat model of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2006-11-14 |
2023-08-12 |
rat |
| Yangtai Guan, Kenneth S Shindler, Philomela Tabuena, A M Rostam. Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice. Journal of neuroimmunology. vol 178. issue 1-2. 2006-11-14. PMID:16828169. |
recently, myelin oligodendrocyte glycoprotein (mog)-specific tcr transgenic mice were found to develop spontaneous isolated optic neuritis in the absence of eae. |
2006-11-14 |
2023-08-12 |
mouse |
| Estelle Bettelli, Dominique Baeten, Anneli Jäger, Raymond A Sobel, Vijay K Kuchro. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of clinical investigation. vol 116. issue 9. 2006-10-30. PMID:16955141. |
we previously generated myelin oligodendrocyte glycoprotein-specific (mog-specific) tcr transgenic mice (tcrmog mice; also referred to as 2d2 mice) and reported that a large proportion of these mice develop spontaneous isolated optic neuritis. |
2006-10-30 |
2023-08-12 |
mouse |
| M B Sättler, D Merkler, K Maier, C Stadelmann, H Ehrenreich, M Bähr, R Die. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell death and differentiation. vol 11 Suppl 2. 2005-06-09. PMID:15459752. |
in the present study, we show that, in rats suffering from myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis, systemic application of erythropoietin (epo) significantly increased survival and function of retinal ganglion cells (rgcs), the neurons that form the axons of the optic nerve. |
2005-06-09 |
2023-08-12 |
rat |
| Mandy L Ford, Brian D Evavol. An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis. European journal of immunology. vol 34. issue 2. 2004-03-30. PMID:14768043. |
an mhc anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces ifn-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis. |
2004-03-30 |
2023-08-12 |
mouse |
| Estelle Bettelli, Maria Pagany, Howard L Weiner, Christopher Linington, Raymond A Sobel, Vijay K Kuchro. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of experimental medicine. vol 197. issue 9. 2003-06-20. PMID:12732654. |
myelin oligodendrocyte glycoprotein-specific t cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. |
2003-06-20 |
2023-08-12 |
mouse |