Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Muriel B Sättler, Mauro Togni, Ivana Gadjanski, Kurt-Wolfram Sühs, Nadine Meyer, Mathias Bähr, Ricarda Die. Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis. Journal of neuroimmunology. vol 193. issue 1-2. 2008-03-04. PMID:18037506. |
we detected important differences in neurodegeneration in various subtypes of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2008-03-04 |
2023-08-12 |
rat |
Martha E Stokely, Manzoor A Bhat, Peter Koule. Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. Journal of neuroscience methods. vol 166. issue 2. 2008-02-14. PMID:17719649. |
tissue microfluorimetry was used to measure seven established markers for human ms pathology in normal and autoimmune optic nerves 13 days after antigen exposure, in a brown norway rat model of myelin oligodendrocyte glycoprotein (mog) peptide (35-55)-induced autoimmune optic neuritis. |
2008-02-14 |
2023-08-12 |
human |
Estelle Bettell. Building different mouse models for human MS. Annals of the New York Academy of Sciences. vol 1103. 2007-07-25. PMID:17376825. |
here, we summarize our published findings on two mouse models: 2d2 myelin oligodendrocyte glycoprotein (mog)-specific t cell receptor (tcr) transgenic mice, which develop spontaneous isolated optic neuritis, and 2d2 mice crossed with mog-specific igh knockin (th) mice, which spontaneously develop a severe form of experimental autoimmune encephalomyelitis (eae) with a selective distribution of meningeal and parenchymal inflammatory lesions in the spinal cord and optic nerves similar to that found in human devic's disease. |
2007-07-25 |
2023-08-12 |
mouse |
Katharina Maier, Antje V Kuhnert, Naimeh Taheri, Muriel B Sättler, Maria K Storch, Sarah K Williams, Mathias Bähr, Ricarda Die. Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study. The American journal of pathology. vol 169. issue 4. 2006-11-24. PMID:17003491. |
after myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis became clinically manifest, optic neuritis was monitored by recording visual evoked potentials. |
2006-11-24 |
2023-08-12 |
human |
Muriel B Sättler, Iris Demmer, Sarah K Williams, Katharina Maier, Doron Merkler, Ivana Gadjanski, Christine Stadelmann, Mathias Bähr, Ricarda Die. Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764858. |
we have characterized previously time course and mechanisms of neuronal apoptosis in a rat model of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2006-11-14 |
2023-08-12 |
rat |
Yangtai Guan, Kenneth S Shindler, Philomela Tabuena, A M Rostam. Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice. Journal of neuroimmunology. vol 178. issue 1-2. 2006-11-14. PMID:16828169. |
recently, myelin oligodendrocyte glycoprotein (mog)-specific tcr transgenic mice were found to develop spontaneous isolated optic neuritis in the absence of eae. |
2006-11-14 |
2023-08-12 |
mouse |
Estelle Bettelli, Dominique Baeten, Anneli Jäger, Raymond A Sobel, Vijay K Kuchro. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. The Journal of clinical investigation. vol 116. issue 9. 2006-10-30. PMID:16955141. |
we previously generated myelin oligodendrocyte glycoprotein-specific (mog-specific) tcr transgenic mice (tcrmog mice; also referred to as 2d2 mice) and reported that a large proportion of these mice develop spontaneous isolated optic neuritis. |
2006-10-30 |
2023-08-12 |
mouse |
M B Sättler, D Merkler, K Maier, C Stadelmann, H Ehrenreich, M Bähr, R Die. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell death and differentiation. vol 11 Suppl 2. 2005-06-09. PMID:15459752. |
in the present study, we show that, in rats suffering from myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis, systemic application of erythropoietin (epo) significantly increased survival and function of retinal ganglion cells (rgcs), the neurons that form the axons of the optic nerve. |
2005-06-09 |
2023-08-12 |
rat |
Mandy L Ford, Brian D Evavol. An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis. European journal of immunology. vol 34. issue 2. 2004-03-30. PMID:14768043. |
an mhc anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces ifn-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis. |
2004-03-30 |
2023-08-12 |
mouse |
Estelle Bettelli, Maria Pagany, Howard L Weiner, Christopher Linington, Raymond A Sobel, Vijay K Kuchro. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of experimental medicine. vol 197. issue 9. 2003-06-20. PMID:12732654. |
myelin oligodendrocyte glycoprotein-specific t cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. |
2003-06-20 |
2023-08-12 |
mouse |