| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tadashi Adachi, Kenichi Yasui, Toshiyuki Takahashi, Kazuo Fujihara, Yasuhiro Watanabe, Kenji Nakashim. Anti-myelin Oligodendrocyte Glycoprotein Antibodies in a Patient with Recurrent Optic Neuritis Involving the Cerebral White Matter and Brainstem. Internal medicine (Tokyo, Japan). vol 55. issue 10. 2017-03-28. PMID:27181546. |
we herein report a case of recurrent optic neuritis involving the cerebral white matter and brainstem in a patient positive for anti-myelin oligodendrocyte glycoprotein (mog) antibodies. |
2017-03-28 |
2023-08-13 |
Not clear |
| Soichiro Numa, Takashi Kasai, Takayuki Kondo, Yukie Kushimura, Ayaka Kimura, Hisashi Takahashi, Kanako Morita, Akihiro Tanaka, Yu-Ichi Noto, Tomoyuki Ohara, Masanori Nakagawa, Toshiki Mizun. An Adult Case of Anti-Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Multiphasic Acute Disseminated Encephalomyelitis at 33-year Intervals. Internal medicine (Tokyo, Japan). vol 55. issue 6. 2016-10-11. PMID:26984094. |
acute disseminated encephalomyelitis (adem) followed by optic neuritis (on) has been reported as a distinct phenotype associated with anti-myelin oligodendrocyte protein (mog) antibody. |
2016-10-11 |
2023-08-13 |
Not clear |
| Elena H Martinez-Lapiscina, Maria Sepulveda, Ruben Torres-Torres, Salut Alba-Arbalat, Sara Llufriu, Yolanda Blanco, Ana M Guerrero-Zamora, Nuria Sola-Valls, Santiago Ortiz-Perez, Pablo Villoslada, Bernardo Sanchez-Dalmau, Albert Sai. Usefulness of optical coherence tomography to distinguish optic neuritis associated with AQP4 or MOG in neuromyelitis optica spectrum disorders. Therapeutic advances in neurological disorders. vol 9. issue 5. 2016-09-01. PMID:27582898. |
usefulness of optical coherence tomography to distinguish optic neuritis associated with aqp4 or mog in neuromyelitis optica spectrum disorders. |
2016-09-01 |
2023-08-13 |
Not clear |
| Sudarshini Ramanathan, Russell C Dale, Fabienne Brilo. Anti-MOG antibody: The history, clinical phenotype, and pathogenicity of a serum biomarker for demyelination. Autoimmunity reviews. vol 15. issue 4. 2016-08-15. PMID:26708342. |
there is now international consensus that anti-mog antibodies are important in both pediatric and adult demyelination, and the clinical association of mog antibody-associated demyelination has been refined to include acute disseminated encephalomyelitis, relapsing and bilateral optic neuritis, and transverse myelitis. |
2016-08-15 |
2023-08-13 |
human |
| Hideki Nakajima, Masakatsu Motomura, Keiko Tanaka, Azusa Fujikawa, Ruka Nakata, Yasuhiro Maeda, Tomoaki Shima, Akihiro Mukaino, Shunsuke Yoshimura, Teiichiro Miyazaki, Hirokazu Shiraishi, Atsushi Kawakami, Akira Tsujin. Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis. BMJ open. vol 5. issue 4. 2016-01-05. PMID:25838512. |
to investigate the differences of clinical features, cerebrospinal fluid (csf), mri findings and response to steroid therapies between patients with optic neuritis (on) who have myelin oligodendrocyte glycoprotein (mog) antibodies and those who have seronegative on. |
2016-01-05 |
2023-08-13 |
Not clear |
| Rie S Tsuburaya, Naoki Miki, Keiko Tanaka, Takashi Kageyama, Kaori Irahara, Souichi Mukaida, Kazuhiro Shiraishi, Masami Tanak. Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies in a Japanese boy with recurrent optic neuritis. Brain & development. vol 37. issue 1. 2015-08-04. PMID:24582475. |
anti-myelin oligodendrocyte glycoprotein (mog) antibodies in a japanese boy with recurrent optic neuritis. |
2015-08-04 |
2023-08-12 |
Not clear |
| Akihiko Miyauchi, Yukifumi Monden, Meri Watanabe, Hideo Sugie, Mitsuya Morita, Takeshi Kezuka, Mariko Momoi, Takanori Yamagat. Persistent presence of the anti-myelin oligodendrocyte glycoprotein autoantibody in a pediatric case of acute disseminated encephalomyelitis followed by optic neuritis. Neuropediatrics. vol 45. issue 3. 2015-01-21. PMID:24610298. |
we report the case of a 5-year-old japanese girl who initially had acute disseminated encephalomyelitis (adem) and was positive for the myelin oligodendrocyte glycoprotein (mog) antibodies and developed unilateral optic neuritis (on) 71 days after adem onset. |
2015-01-21 |
2023-08-12 |
Not clear |
| Masami Tanaka, Keiko Tanak. Anti-MOG antibodies in adult patients with demyelinating disorders of the central nervous system. Journal of neuroimmunology. vol 270. issue 1-2. 2014-06-05. PMID:24703097. |
here, sera samples from 48 consecutive japanese patients with myelitis or optic neuritis (on), but negative for anti-aquaporin (aqp) 4 antibodies (abs), and 14 anti-aqp4 ab-positive patients were tested for anti-mog abs using a cell-based immunofluorescence assay with full-length human mog cdna. |
2014-06-05 |
2023-08-13 |
human |
| Markus Reindl, Franziska Di Pauli, Kevin Rostásy, Thomas Berge. The spectrum of MOG autoantibody-associated demyelinating diseases. Nature reviews. Neurology. vol 9. issue 8. 2014-01-15. PMID:23797245. |
cell-based immunoassays using mog expressed in mammalian cells have demonstrated the presence of high-titre mog antibodies in paediatric patients with acute disseminated encephalomyelitis, ms, aquaporin-4-seronegative neuromyelitis optica, or isolated optic neuritis or transverse myelitis, but only rarely in adults with these disorders. |
2014-01-15 |
2023-08-12 |
human |
| Marie C Mayer, Constanze Breithaupt, Markus Reindl, Kathrin Schanda, Kevin Rostásy, Thomas Berger, Russell C Dale, Fabienne Brilot, Tomas Olsson, Dieter Jenne, Anne-Katrin Pröbstel, Klaus Dornmair, Hartmut Wekerle, Reinhard Hohlfeld, Brenda Banwell, Amit Bar-Or, Edgar Mein. Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of immunology (Baltimore, Md. : 1950). vol 191. issue 7. 2013-11-26. PMID:24014878. |
we expressed mutants of mog on human hela cells and analyzed sera from 111 patients (104 children, 7 adults) who recognized cell-bound human mog, but had different diseases, including acute disseminated encephalomyelitis (adem), one episode of transverse myelitis or optic neuritis, multiple sclerosis (ms), anti-aquaporin-4 (aqp4)-negative neuromyelitis optica (nmo), and chronic relapsing inflammatory optic neuritis (crion). |
2013-11-26 |
2023-08-12 |
mouse |
| Takeshi Kezuka, Yoshihiko Usui, Naoyuki Yamakawa, Yoshimichi Matsunaga, Ryusaku Matsuda, Masayuki Masuda, Hiroya Utsumi, Keiko Tanaka, Hiroshi Got. Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. vol 32. issue 2. 2012-11-06. PMID:22157536. |
mog antigen is currently considered as a cause of optic neuritis (on) associated with ms because immunization with mog antigen derived from oligodendrocytes induces murine on with myelitis. |
2012-11-06 |
2023-08-12 |
Not clear |
| Kevin Rostasy, Simone Mader, Kathrin Schanda, Peter Huppke, Jutta Gärtner, Verena Kraus, Michael Karenfort, Daniel Tibussek, Astrid Blaschek, Barbara Bajer-Kornek, Steffen Leitz, Mareike Schimmel, Franziska Di Pauli, Thomas Berger, Markus Reind. Anti-myelin oligodendrocyte glycoprotein antibodies in pediatric patients with optic neuritis. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22371853. |
to study the humoral immune response directed at myelin oligodendrocyte glycoprotein (mog)in pediatric patients with isolated and recurrent optic neuritis(on). |
2012-08-31 |
2023-08-12 |
Not clear |
| Muriel B Sättler, Mauro Togni, Ivana Gadjanski, Kurt-Wolfram Sühs, Nadine Meyer, Mathias Bähr, Ricarda Die. Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis. Journal of neuroimmunology. vol 193. issue 1-2. 2008-03-04. PMID:18037506. |
we detected important differences in neurodegeneration in various subtypes of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2008-03-04 |
2023-08-12 |
rat |
| Martha E Stokely, Manzoor A Bhat, Peter Koule. Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. Journal of neuroscience methods. vol 166. issue 2. 2008-02-14. PMID:17719649. |
tissue microfluorimetry was used to measure seven established markers for human ms pathology in normal and autoimmune optic nerves 13 days after antigen exposure, in a brown norway rat model of myelin oligodendrocyte glycoprotein (mog) peptide (35-55)-induced autoimmune optic neuritis. |
2008-02-14 |
2023-08-12 |
human |
| Estelle Bettell. Building different mouse models for human MS. Annals of the New York Academy of Sciences. vol 1103. 2007-07-25. PMID:17376825. |
here, we summarize our published findings on two mouse models: 2d2 myelin oligodendrocyte glycoprotein (mog)-specific t cell receptor (tcr) transgenic mice, which develop spontaneous isolated optic neuritis, and 2d2 mice crossed with mog-specific igh knockin (th) mice, which spontaneously develop a severe form of experimental autoimmune encephalomyelitis (eae) with a selective distribution of meningeal and parenchymal inflammatory lesions in the spinal cord and optic nerves similar to that found in human devic's disease. |
2007-07-25 |
2023-08-12 |
mouse |
| Muriel B Sättler, Iris Demmer, Sarah K Williams, Katharina Maier, Doron Merkler, Ivana Gadjanski, Christine Stadelmann, Mathias Bähr, Ricarda Die. Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764858. |
we have characterized previously time course and mechanisms of neuronal apoptosis in a rat model of myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis. |
2006-11-14 |
2023-08-12 |
rat |
| Yangtai Guan, Kenneth S Shindler, Philomela Tabuena, A M Rostam. Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice. Journal of neuroimmunology. vol 178. issue 1-2. 2006-11-14. PMID:16828169. |
recently, myelin oligodendrocyte glycoprotein (mog)-specific tcr transgenic mice were found to develop spontaneous isolated optic neuritis in the absence of eae. |
2006-11-14 |
2023-08-12 |
mouse |
| M B Sättler, D Merkler, K Maier, C Stadelmann, H Ehrenreich, M Bähr, R Die. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Cell death and differentiation. vol 11 Suppl 2. 2005-06-09. PMID:15459752. |
in the present study, we show that, in rats suffering from myelin oligodendrocyte glycoprotein (mog)-induced optic neuritis, systemic application of erythropoietin (epo) significantly increased survival and function of retinal ganglion cells (rgcs), the neurons that form the axons of the optic nerve. |
2005-06-09 |
2023-08-12 |
rat |
| Hui Shao, Zhigang Huang, Sheher L Sun, Henry J Kaplan, Deming Su. Myelin/oligodendrocyte glycoprotein-specific T-cells induce severe optic neuritis in the C57BL/6 mouse. Investigative ophthalmology & visual science. vol 45. issue 11. 2004-12-08. PMID:15505056. |
to determine the relationship between optic neuritis (on) and eae, we examined the incidence of on in c57bl/6 (b6) mice immunized with a myelin oligodendrocyte/glycoprotein (mog)-derived peptide or injected with mog-specific t cells, which are known to induce eae. |
2004-12-08 |
2023-08-12 |
mouse |
| Estelle Bettelli, Maria Pagany, Howard L Weiner, Christopher Linington, Raymond A Sobel, Vijay K Kuchro. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. The Journal of experimental medicine. vol 197. issue 9. 2003-06-20. PMID:12732654. |
optic neuritis without eae could also be induced in these mice by sensitization with suboptimal doses of mog. |
2003-06-20 |
2023-08-12 |
mouse |