| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Eslami, M Ghiasian, B Mohamadrahimi, N Jiriaee, A Eslamighayou. Optical coherence tomography (OCT) findings in patients with Parkinson's disease presenting to Farshchian Hospital (Sina) in 2019 compared to the normal population. Journal francais d'ophtalmologie. vol 48. issue 2. 2024-12-11. PMID:39662306. |
one of the practical methods in diagnosing and evaluating the progress of neurodegenerative diseases is the use of optical coherence tomography (oct), with which it is possible to accurately measure the thickness of the layers of the retina, as well as the thickness and volume of the macula. |
2024-12-11 |
2024-12-14 |
Not clear |
| Qianzi Jin, Suyu Wang, Yujia Yao, Qin Jiang, Keran L. The gut-eye axis: from brain neurodegenerative diseases to age-related macular degeneration. Neural regeneration research. vol 20. issue 10. 2024-11-29. PMID:39435619. |
age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision. |
2024-11-29 |
2024-12-01 |
Not clear |
| Wenxin Ma, Lian Zhao, Biying Xu, Robert N Fariss, T Michael Redmond, Jizhong Zou, Wai T Wong, Wei L. Human-induced pluripotent stem cell-derived microglia integrate into mouse retina and recapitulate features of endogenous microglia. eLife. vol 12. 2024-11-08. PMID:39514271. |
microglia exhibit both maladaptive and adaptive roles in the pathogenesis of neurodegenerative diseases and have emerged as a cellular target for central nervous system (cns) disorders, including those affecting the retina. |
2024-11-08 |
2024-11-16 |
mouse |
| Nina Donkor, Charles C Kiehlbauch, Nathaniel Pappenhagen, Gary C Look, Autumn B Morgan, Rick Shin, Mary E Hamby, Denise M Inma. Neuroprotective Effect of Sigma-2 Modulator CT2074 in a Mouse Model of Ocular Hypertension. Experimental eye research. 2024-10-31. PMID:39481675. |
ocular neurodegenerative diseases, particularly glaucoma, represent a significant global cause of blindness, with current therapies inadequately addressing the degeneration of the retina and optic nerve. |
2024-10-31 |
2024-11-03 |
mouse |
| Safaa Zeineddin, Ghadeer Matar, Yasmin Abosaif, Mohammed Abunada, Belal Aldabbou. A novel pathogenic variant in the KCTD7 gene in a patient with neuronal ceroid lipofuscinosis (CLN14): a case report and review of the literature. BMC neurology. vol 24. issue 1. 2024-10-01. PMID:39350080. |
neuronal ceroid lipofuscinosis (ncl) is a heterogeneous group of 13 rare, progressive neurodegenerative diseases of the brain and retina. |
2024-10-01 |
2024-10-03 |
Not clear |
| Edward P Esposito, Ian C Han, Thomas V Johnso. Gene and cell-based therapies for retinal and optic nerve disease. Handbook of clinical neurology. vol 205. 2024-09-28. PMID:39341657. |
leading causes of blindness worldwide include neurodegenerative diseases of the retina, which cause irreversible loss of retinal pigment epithelium (rpe) and photoreceptors, and optic neuropathies, which result in retinal ganglion cell (rgc) death. |
2024-09-28 |
2024-10-01 |
human |
| Frederique J Hart de Ruyter, Manon J A P Evers, Tjado H J Morrema, Anke A Dijkstra, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J Rozemuller, Jeroen J M Hoozeman. Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. Acta neuropathologica. vol 148. issue 1. 2024-08-19. PMID:39160362. |
neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. |
2024-08-19 |
2024-08-22 |
Not clear |
| Frederique J Hart de Ruyter, Manon J A P Evers, Tjado H J Morrema, Anke A Dijkstra, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J Rozemuller, Jeroen J M Hoozeman. Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. Acta neuropathologica. vol 148. issue 1. 2024-08-19. PMID:39160362. |
the retina is increasingly recognised as a potential source of biomarkers for neurodegenerative diseases. |
2024-08-19 |
2024-08-22 |
Not clear |
| Frederique J Hart de Ruyter, Manon J A P Evers, Tjado H J Morrema, Anke A Dijkstra, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J Rozemuller, Jeroen J M Hoozeman. Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. Acta neuropathologica. vol 148. issue 1. 2024-08-19. PMID:39160362. |
this study aims to assess proteinopathy in a post-mortem cohort with different neurodegenerative diseases and assess the presence of the primary pathology in the retina. |
2024-08-19 |
2024-08-22 |
Not clear |
| Frederique J Hart de Ruyter, Manon J A P Evers, Tjado H J Morrema, Anke A Dijkstra, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J Rozemuller, Jeroen J M Hoozeman. Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. Acta neuropathologica. vol 148. issue 1. 2024-08-19. PMID:39160362. |
from this study, we conclude that the retina reflects the presence of the major hallmark proteins associated with neurodegenerative diseases. |
2024-08-19 |
2024-08-22 |
Not clear |
| Frederique J Hart de Ruyter, Manon J A P Evers, Tjado H J Morrema, Anke A Dijkstra, Jurre den Haan, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J Rozemuller, Jeroen J M Hoozeman. Neuropathological hallmarks in the post-mortem retina of neurodegenerative diseases. Acta neuropathologica. vol 148. issue 1. 2024-08-19. PMID:39160362. |
although low or moderate levels of copathology were found in the brains of most cases, the retina primarily manifested protein aggregates associated with the main neurodegenerative disease. |
2024-08-19 |
2024-08-22 |
Not clear |
| Paul Trlin, Jenny Gong, Katie K N Tran, Vickie H Y Wong, Pei Ying Lee, Anh Hoang, Da Zhao, Leah C Beauchamp, Jeremiah K H Lim, Andrew Metha, Kevin J Barnham, David I Finkelstein, Bang V Bui, Phillip Bedggood, Christine T O Nguye. Retinal hyperspectral imaging in mouse models of Parkinson's disease and healthy aging. Scientific reports. vol 14. issue 1. 2024-07-12. PMID:38997314. |
parkinson's disease is another neurodegenerative disease where brain pathobiology such as alpha-synuclein and iron overaccumulation have been implicated in the retina. |
2024-07-12 |
2024-07-15 |
mouse |
| Larisa Cujbă, Ana Banc, Cristina Stan, Tudor Drugan, Cristina Nicul. Macular OCT's Proficiency in Identifying Retrochiasmal Visual Pathway Lesions in Multiple Sclerosis-A Pilot Study. Diagnostics (Basel, Switzerland). vol 14. issue 12. 2024-06-27. PMID:38928637. |
multiple sclerosis (ms) is a neurodegenerative disease that can lead to damage of the optic nerve and retina, which can be depicted by oct. |
2024-06-27 |
2024-06-29 |
human |
| Ying Zhou, Yuwei Yang, Ting Qi, Zhuoran Hou, Qinyu Ge, Zuhong L. Transcriptome Study of rd1Mouse Brain and Association with Parkinson's Disease. ACS omega. vol 9. issue 24. 2024-06-24. PMID:38911794. |
degeneration of the retina is intrinsically associated with the pathogenesis and progression of neurodegenerative diseases. |
2024-06-24 |
2024-06-26 |
mouse |
| Anne Rombaut, Danica Jovancevic, Raymond Ching-Bong Wong, Alan Nicol, Rune Brautaset, David I Finkelstein, Christine T O Nguyen, James R Tribble, Pete A William. Intravitreal MPTP drives retinal ganglion cell loss with oral nicotinamide treatment providing robust neuroprotection. Acta neuropathologica communications. vol 12. issue 1. 2024-05-22. PMID:38773545. |
the retina is often affected in common neurodegenerative diseases such as parkinson's and alzheimer's disease. |
2024-05-22 |
2024-05-27 |
mouse |
| Jose A Fernández-Albarral, Ana I Ramírez, Rosa de Hoz, José A Matamoros, Elena Salobrar-García, Lorena Elvira-Hurtado, Inés López-Cuenca, Lidia Sánchez-Puebla, Juan J Salazar, José M Ramíre. Glaucoma: from pathogenic mechanisms to retinal glial cell response to damage. Frontiers in cellular neuroscience. vol 18. 2024-02-09. PMID:38333055. |
glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss of retinal ganglion cells (rgcs) leading to visual loss. |
2024-02-09 |
2024-02-11 |
Not clear |
| Cornelia Andreea Tănasie, Alexandra Oltea Dan, Oana Maria Ică, Maria Filoftea Mercuț, George Mitroi, Citto-Iulian Taisescu, Veronica Sfredel, Ramona Ingrid Corbeanu, Carmen Luminița Mocanu, Ciprian Danielesc. Retinal Functional Impairment in Diabetic Retinopathy. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255151. |
diabetic retinopathy (dr) is a neurodegenerative disease of the retina. |
2024-01-23 |
2024-01-25 |
Not clear |
| Alex Suh, Joshua Ong, Sharif Amit Kamran, Ethan Waisberg, Phani Paladugu, Nasif Zaman, Prithul Sarker, Alireza Tavakkoli, Andrew G Le. Retina Oculomics in Neurodegenerative Disease. Annals of biomedical engineering. 2023-10-19. PMID:37855949. |
retina oculomics in neurodegenerative disease. |
2023-10-19 |
2023-11-08 |
Not clear |
| Mattia Di Paolo, Francesca Corsi, Chiara Cerri, Silvia Bisti, Ilaria Piano, Claudia Gargin. A Window to the Brain: The Retina to Monitor the Progression and Efficacy of Saffron Repron Pharmaceuticals (Basel, Switzerland). vol 16. issue 9. 2023-09-28. PMID:37765115. |
a window to the brain: the retina to monitor the progression and efficacy of saffron repron a mechanism shared by most neurodegenerative diseases, like alzheimer's disease (ad) and parkinson's disease (pd), is neuroinflammation. |
2023-09-28 |
2023-10-07 |
mouse |
| Frederique J Hart de Ruyter, Tjado H J Morrema, Jurre den Haan, Gina Gase, Jos W R Twisk, Johannes F de Boer, Philip Scheltens, Femke H Bouwman, Frank D Verbraak, Annemieke J M Rozemuller, Jeroen J M Hoozeman. α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies. NPJ Parkinson's disease. vol 9. issue 1. 2023-08-28. PMID:37640753. |
specific protein aggregates associated with neurodegenerative diseases are present in the retina and could be visualised in a non-invasive way. |
2023-08-28 |
2023-09-07 |
Not clear |