| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryuji Terayama, Yoshio Bando, Ying-Ping Jiang, Branka Mitrovic, Shigetaka Yoshid. Differential expression of protease M/neurosin in oligodendrocytes and their progenitors in an animal model of multiple sclerosis. Neuroscience letters. vol 382. issue 1-2. 2005-07-11. PMID:15911126. |
to determine the possible involvement of protease m/neurosin in demyelinating diseases of the cns, we examined its expression in myelin oligodendrocyte glycoprotein (mog)-induced experimental autoimmune encephalomyelitis (eae), a recognized animal model of multiple sclerosis (ms). |
2005-07-11 |
2023-08-12 |
mouse |
| Olaf Maier, Tiemen van der Heide, Anne-Marie van Dam, Wia Baron, Hans de Vries, Dick Hoekstr. Alteration of the extracellular matrix interferes with raft association of neurofascin in oligodendrocytes. Potential significance for multiple sclerosis? Molecular and cellular neurosciences. vol 28. issue 2. 2005-06-28. PMID:15691718. |
remyelination, as potential treatment for demyelinating diseases like multiple sclerosis (ms), requires the formation of new axoglial interactions by differentiating oligodendrocyte progenitor cells. |
2005-06-28 |
2023-08-12 |
rat |
| Ikuo Tsunoda, Li-Qing Kuang, Isaac Z M Igenge, Robert S Fujinam. Converting relapsing remitting to secondary progressive experimental allergic encephalomyelitis (EAE) by ultraviolet B irradiation. Journal of neuroimmunology. vol 160. issue 1-2. 2005-04-28. PMID:15710465. |
we induced experimental allergic encephalomyelitis (eae) in sjl/j mice, an animal model for multiple sclerosis (ms), using myelin oligodendrocyte glycoprotein (mog)(92-106) peptide, following ultraviolet (uv) irradiation. |
2005-04-28 |
2023-08-12 |
mouse |
| A Compsto. Mechanisms of axon-glial injury of the optic nerve. Eye (London, England). vol 18. issue 11. 2005-04-25. PMID:15534604. |
the phases of symptom onset, recovery, persistence, and progression in multiple sclerosis can be summarized as functional impairment with intact structure due to direct effects of inflammatory mediators; demyelination and axonal injury with recovery through plasticity and remyelination; and chronic axonal loss due to failure of enduring remyelination from loss of trophic support for axons normally provided by cells of the oligodendrocyte lineage. |
2005-04-25 |
2023-08-12 |
Not clear |
| Cecilia B Marta, Michael B Montano, Christopher M Taylor, Ava L Taylor, Rashmi Bansal, Steven E Pfeiffe. Signaling cascades activated upon antibody cross-linking of myelin oligodendrocyte glycoprotein: potential implications for multiple sclerosis. The Journal of biological chemistry. vol 280. issue 10. 2005-04-19. PMID:15634682. |
signaling cascades activated upon antibody cross-linking of myelin oligodendrocyte glycoprotein: potential implications for multiple sclerosis. |
2005-04-19 |
2023-08-12 |
Not clear |
| Cecilia B Marta, Michael B Montano, Christopher M Taylor, Ava L Taylor, Rashmi Bansal, Steven E Pfeiffe. Signaling cascades activated upon antibody cross-linking of myelin oligodendrocyte glycoprotein: potential implications for multiple sclerosis. The Journal of biological chemistry. vol 280. issue 10. 2005-04-19. PMID:15634682. |
in particular, antibodies to myelin oligodendrocyte glycoprotein (mog) are elevated in multiple sclerosis patients, and they have been implicated as mediators of demyelination. |
2005-04-19 |
2023-08-12 |
Not clear |
| Andreas Bitsch, Alexander Dressel, Kathrin Meier, Timon Bogumil, Florian Deisenhammer, Hayrettin Tumani, Bernd Kitze, Sigrid Poser, Frank Webe. Autoantibody synthesis in primary progressive multiple sclerosis patients treated with interferon beta-1b. Journal of neurology. vol 251. issue 12. 2005-03-29. PMID:15645350. |
we conducted an open-labeled clinical trial of interferon beta-1b (ifnb) treatment in 20 patients with primary progressive multiple sclerosis (ppms) and longitudinally monitored autoantibodies against double-stranded dna (dsdna), thyroid peroxidase (tpo),myelin basic protein (mbp), myelin oligodendrocyte glycoprotein (mog), synapsin and s-100b. |
2005-03-29 |
2023-08-12 |
Not clear |
| A K Foote, W F Blakemor. Inflammation stimulates remyelination in areas of chronic demyelination. Brain : a journal of neurology. vol 128. issue Pt 3. 2005-03-28. PMID:15699059. |
using the taiep rat and a combination of x-irradiation and cell transplantation, it has been possible to address a number of questions concerning remyelination failure in chronic multiple sclerosis lesions, such as whether chronically demyelinated axons have undergone changes that render them refractory to remyelination and why remyelination is absent when oligodendrocyte progenitor cells (opcs) are present. |
2005-03-28 |
2023-08-12 |
rat |
| Michael P Pende. Oligodendrocyte apoptosis before immune attack in multiple sclerosis? Annals of neurology. vol 57. issue 1. 2005-03-14. PMID:15622546. |
oligodendrocyte apoptosis before immune attack in multiple sclerosis? |
2005-03-14 |
2023-08-12 |
Not clear |
| Anthony T Reder, Joel J Oge. Anti-myelin oligodendrocyte glycoprotein antibodies in multiple sclerosis. Neurology. vol 62. issue 11. 2004-12-20. PMID:15184588. |
anti-myelin oligodendrocyte glycoprotein antibodies in multiple sclerosis. |
2004-12-20 |
2023-08-12 |
Not clear |
| V Lampasona, D Franciotta, R Furlan, S Zanaboni, R Fazio, E Bonifacio, G Comi, G Martin. Similar low frequency of anti-MOG IgG and IgM in MS patients and healthy subjects. Neurology. vol 62. issue 11. 2004-12-20. PMID:15184621. |
the authors used a liquid-phase radiobinding assay to measure serum anti-myelin oligodendrocyte protein (mog) immunoglobulin (ig) g in 87 patients with multiple sclerosis (ms), in 12 patients with encephalomyelitis, and in 47 healthy subjects. |
2004-12-20 |
2023-08-12 |
human |
| Steven Petratos, Michael F Gonzales, Michael F Azari, Mark Marriott, Rebecca A Minichiello, Kylie A Shipham, Christos Profyris, Antonis Nicolaou, Kristy Boyle, Surindar S Cheema, Trevor J Kilpatric. Expression of the low-affinity neurotrophin receptor, p75(NTR), is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination. Glia. vol 48. issue 1. 2004-10-27. PMID:15326616. |
the low-affinity neurotrophin receptor, p75(ntr), may be one of these regulators; however, its expression profile by oligodendroglia within the multiple sclerosis (ms) brain remains uncertain. |
2004-10-27 |
2023-08-12 |
Not clear |
| Malin Hultqvist, Peter Olofsson, Jens Holmberg, B Thomas Bäckström, Jesper Tordsson, Rikard Holmdah. Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 34. 2004-10-18. PMID:15310853. |
the enhancing effect of the mutated ncf1 could also be shown to be more general in that it enhanced myelin oligodendrocyte glycoprotein protein-induced experimental autoimmune encephalomyelitis, a model for multiple sclerosis. |
2004-10-18 |
2023-08-12 |
mouse |
| Mark F Stidworthy, Stephane Genoud, Wen-Wu Li, Dino P Leone, Ned Mantei, Ueli Suter, Robin J M Frankli. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain : a journal of neurology. vol 127. issue Pt 9. 2004-10-15. PMID:15289265. |
jagged signalling via notch receptors on oligodendrocyte precursor cells (opcs) inhibits their differentiation during development and the finding that both notch and jagged are expressed in multiple sclerosis lesions has fostered the view that this signalling pathway may explain remyelination failure. |
2004-10-15 |
2023-08-12 |
mouse |
| Emily Mathey, Constanze Breithaupt, Anna S Schubart, Christopher Liningto. Commentary: Sorting the wheat from the chaff: identifying demyelinating components of the myelin oligodendrocyte glycoprotein (MOG)-specific autoantibody repertoire. European journal of immunology. vol 34. issue 8. 2004-09-14. PMID:15259003. |
myelin oligodendrocyte glycoprotein (mog) is the only myelin protein known to initiate a demyelinating autoantibody response in eae, an animal model for multiple sclerosis (ms). |
2004-09-14 |
2023-08-12 |
human |
| Hans-Christian von Büdingen, Stephen L Hauser, Jean-Christophe Ouallet, Naoyuki Tanuma, Til Menge, Claude P Genai. Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune demyelination. European journal of immunology. vol 34. issue 8. 2004-09-14. PMID:15259004. |
preliminary observations of humoral immunity against the myelin oligodendrocyte glycoprotein (mog) in experimental allergic encephalomyelitis (eae) and human multiple sclerosis (ms) suggest that a subset of anti-mog autoantibodies directed against conformational epitopes is of pathogenic predominance. |
2004-09-14 |
2023-08-12 |
human |
| Maja Jagodic, Kristina Becanovic, Jian Rong Sheng, Xingchen Wu, Liselotte Bäckdahl, Johnny C Lorentzen, Erik Wallström, Tomas Olsso. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 2. 2004-08-27. PMID:15240732. |
myelin oligodendrocyte glycoprotein-induced eae is a chronic relapsing disease that closely mimics key features of multiple sclerosis. |
2004-08-27 |
2023-08-12 |
mouse |
| Alastair Compsto. The pathogenesis and basis for treatment in multiple sclerosis. Clinical neurology and neurosurgery. vol 106. issue 3. 2004-08-26. PMID:15177777. |
the phases of symptom onset, recovery, persistence and progression in multiple sclerosis can be summarized as functional impairment with intact structure due to direct effects of inflammatory mediators, demyelination and axonal injury with recovery through plasticity and remyelination, and chronic axonal loss due to failure of enduring remyelination from loss of trophic support for axons normally provided by cells of the oligodendrocyte lineage. |
2004-08-26 |
2023-08-12 |
Not clear |
| Alireza Minagar, Eduardo Gonzalez Toledo, J Steven Alexander, Roger E Kelle. Pathogenesis of brain and spinal cord atrophy in multiple sclerosis. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 14. issue 3 Suppl. 2004-08-26. PMID:15228754. |
for more than a century, multiple sclerosis was viewed as a disease process characterized by oligodendrocyte and myelin loss, and research into the pathogenesis of multiple sclerosis was mainly focused on the mechanisms of inflammation. |
2004-08-26 |
2023-08-12 |
Not clear |
| Alireza Minagar, Eduardo Gonzalez Toledo, J Steven Alexander, Roger E Kelle. Pathogenesis of brain and spinal cord atrophy in multiple sclerosis. Journal of neuroimaging : official journal of the American Society of Neuroimaging. vol 14. issue 3 Suppl. 2004-08-26. PMID:15228754. |
neurodegeneration and axonal loss in patients with multiple sclerosis are initially accompanied by a local response from oligodendrocyte progenitor cells and some remyelination. |
2004-08-26 |
2023-08-12 |
Not clear |