All Relations between Mood Disorders and hippocampus

Publication Sentence Publish Date Extraction Date Species
Jianhao Wang, Hang Yu, Xiang Li, Fang Li, Hongyu Chen, Xi Zhang, Yamei Wang, Ruifeng Xu, Feng Gao, Jiabei Wang, Pai Liu, Yuke Shi, Dongdong Qin, Yiyi Li, Songyan Liu, Shuai Ding, Xin-Ya Gao, Zhi-Hao Wan. A TrkB cleavage fragment in hippocampus promotes Depressive-Like behavior in mice. Brain, behavior, and immunity. 2024-03-31. PMID:38555992. decreased hippocampal tropomyosin receptor kinase b (trkb) level is implicated in the pathophysiology of stress-induced mood disorder and cognitive decline. 2024-03-31 2024-04-03 mouse
Michał Lis, Tymoteusz Miłuch, Maciej Majdowski, Tomasz Zawodn. A link between ghrelin and major depressive disorder: a mini review. Frontiers in psychiatry. vol 15. 2024-03-28. PMID:38544844. ghrelin may influence mood disorders in various ways: by regulating stress response or inflammation or altering neurotransmission in the amygdala, dorsal raphe nucleus, or hippocampus, brain regions previously connected to the pathophysiology of mdd. 2024-03-28 2024-03-30 human
Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. decreased hippocampal synaptic plasticity is an important pathological change in stress-related mood disorders, including major depressive disorder. 2024-03-16 2024-03-19 mouse
Tahmineh Mokhtari, Kadir Uluda. Role of NLRP3 Inflammasome in Post-Spinal-Cord-Injury Anxiety and Depression: Molecular Mechanisms and Therapeutic Implications. ACS chemical neuroscience. 2023-12-18. PMID:38109051. dysregulation of the nlrp3 inflammasome in key brain regions associated with pain processing, such as the prefrontal cortex and hippocampus, contributes to the development of mood disorders following sci. 2023-12-18 2023-12-21 human
Hirofumi Hirakawa, Takeshi Terao, Koji Hatano, Masanao Shirahama, Tsuyoshi Kugimiya, Kentaro Kohno, Hiroyuki Matsuta, Tsuyoshi Shimomura, Minoru Fujik. Increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study. Translational psychiatry. vol 13. issue 1. 2023-12-15. PMID:38102115. increased volume of the left hippocampal dentate gyrus after 4 weeks of bright light exposure in patients with mood disorders: a randomized controlled study. 2023-12-15 2023-12-18 human
Thalita Mázala-de-Oliveira, Bruna Teixeira Silva, Paula Campello-Costa, Vinicius Frias Carvalh. The Role of the Adrenal-Gut-Brain Axis on Comorbid Depressive Disorder Development in Diabetes. Biomolecules. vol 13. issue 10. 2023-10-30. PMID:37892186. in this context, we propose here that hypercortisolism, in association with gut dysbiosis, leads to an exacerbation of hippocampal neuroinflammation, glutamatergic transmission, and neuronal apoptosis, leading to the development and aggravation of depression and to resistance to treatment of this mood disorder in diabetic patients. 2023-10-30 2023-11-08 mouse
Xubin Wu, Yuxiang Guo, Jiayue Xue, Yanqing Dong, Yumeng Sun, Bin Wang, Jie Xiang, Yi Li. Abnormal and Changing Information Interaction in Adults with Attention-Deficit/Hyperactivity Disorder Based on Network Motifs. Brain sciences. vol 13. issue 9. 2023-09-28. PMID:37759932. the results showed that the interaction functions of the right hippocampus and the right amygdala were significantly increased, which could lead patients to develop mood disorders. 2023-09-28 2023-10-07 Not clear
Luwen Zhang, Wenjuan Tang, Yinan Ouyang, Miao Zhang, Ruirui Li, Lianping Sun, Chao Liu, Hailing Y. N-palmitoylethanolamine modulates hippocampal neuroplasticity in rats with stress-induced depressive behavior phenotype. European journal of pharmacology. 2023-09-06. PMID:37673363. in conclusion, the therapeutic potential of pea for depressive mood disorders may be through targeting the hippocampal neuroplasticity, including increasing adult neurogenesis and synaptic plasticity, as well as down-regulated neuronal apoptosis, to remodel hippocampal circuitries upon functional integration and pparα pathway may be involved in this process. 2023-09-06 2023-10-07 rat
Basile Coutens, Camille Lejards, Guillaume Bouisset, Laure Verret, Claire Rampon, Bruno P Guiar. Enriched environmental exposure reduces the onset of action of the serotonin norepinephrin reuptake inhibitor venlafaxine through its effect on parvalbumin interneurons plasticity in mice. Translational psychiatry. vol 13. issue 1. 2023-06-26. PMID:37365183. mood disorders are associated with hypothalamic-pituitary-adrenal axis overactivity resulting from a decreased inhibitory feedback exerted by the hippocampus on this brain structure. 2023-06-26 2023-08-14 mouse
Lene C Olsen, Meital Galler, Menno P Witter, Pål Saetrom, Kally C O'Reill. Transcriptional development of the hippocampus and the dorsal-intermediate-ventral axis in rats. Hippocampus. 2023-06-06. PMID:37280038. the dorsal-ventral axis of the hippocampus has behavioral, electrophysiological, anatomical, and transcriptional gradients and abnormal hippocampus development is associated with autism, schizophrenia, epilepsy, and mood disorders. 2023-06-06 2023-08-14 rat
Spiro P Pantazatos, Todd Ogden, Nadine M Melhem, David A Brent, Mohammad Lesanpezeshki, Ainsley Burke, John G Keilp, Jeffrey M Miller, J John Man. Smaller cornu ammonis (CA3) as a potential risk factor for suicidal behavior in mood disorders. Journal of psychiatric research. vol 163. 2023-05-27. PMID:37244064. smaller cornu ammonis (ca3) as a potential risk factor for suicidal behavior in mood disorders. 2023-05-27 2023-08-14 human
Spiro P Pantazatos, Todd Ogden, Nadine M Melhem, David A Brent, Mohammad Lesanpezeshki, Ainsley Burke, John G Keilp, Jeffrey M Miller, J John Man. Smaller cornu ammonis (CA3) as a potential risk factor for suicidal behavior in mood disorders. Journal of psychiatric research. vol 163. 2023-05-27. PMID:37244064. mood disorders and suicidal behavior have moderate heritability and familial transmission, and are associated with smaller hippocampal volumes. 2023-05-27 2023-08-14 human
Spiro P Pantazatos, Todd Ogden, Nadine M Melhem, David A Brent, Mohammad Lesanpezeshki, Ainsley Burke, John G Keilp, Jeffrey M Miller, J John Man. Smaller cornu ammonis (CA3) as a potential risk factor for suicidal behavior in mood disorders. Journal of psychiatric research. vol 163. 2023-05-27. PMID:37244064. we sought to separate the relationships of hippocampal substructure volumes to mood disorder, suicidal behavior, and risk and resilience to both by examining high familial risk individuals (hr) who have passed the age of greatest risk for psychopathology onset. 2023-05-27 2023-08-14 human
Spiro P Pantazatos, Todd Ogden, Nadine M Melhem, David A Brent, Mohammad Lesanpezeshki, Ainsley Burke, John G Keilp, Jeffrey M Miller, J John Man. Smaller cornu ammonis (CA3) as a potential risk factor for suicidal behavior in mood disorders. Journal of psychiatric research. vol 163. 2023-05-27. PMID:37244064. structural brain imaging and hippocampal substructure segmentation quantified cornu ammonis (ca1-4), dentate gyrus, and subiculum gray matter volumes in healthy volunteers (hv, n = 25) and three groups with one or more relatives reporting early-onset mood disorder and suicide attempt: 1. 2023-05-27 2023-08-14 human
Francis M Hughes, Michael R Odom, Anissa Cervantes, Austin J Livingston, J Todd Purve. Why Are Some People with Lower Urinary Tract Symptoms (LUTS) Depressed? New Evidence That Peripheral Inflammation in the Bladder Causes Central Inflammation and Mood Disorders. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769140. meanwhile, studies on mood disorders have found that many are associated with central neuroinflammation, most notably in the hippocampus. 2023-02-11 2023-08-14 Not clear
Nicola Sambuco, Margaret M Bradley, Peter J Lan. Hippocampal and amygdala volumes vary with transdiagnostic psychopathological dimensions of distress, anxious arousal, and trauma. Biological psychology. 2023-01-16. PMID:36646300. the current study measured hippocampal and amygdala volumes in anxiety and mood disorder patients assessing differences that vary dimensionally with transdiagnostic factors of distress, anxious arousal, and trauma, based on a principal components analysis of questionnaires relating to symptomology. 2023-01-16 2023-08-14 Not clear
Yihan Wang, Yating Ren, Tao Hong, Dingqi Lu, Fan Zhang, Yi Cao, Xinchang Wan. Lipidomics Changes in a Murine Model of Neuropsychiatric Lupus. Journal of inflammation research. vol 15. 2022-12-12. PMID:36506783. therefore, this research evaluated the lipidomic analysis in the hippocampus and liver of npsle mice with mood disorders, to explore the influence of the liver-brain axis on this disease. 2022-12-12 2023-08-14 mouse
Laifa Wang, Xueqin Wang, Ling Deng, Hui Zhang, Binsheng He, Wenyu Cao, Yanhui Cu. Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. International immunopharmacology. vol 113. issue Pt B. 2022-11-17. PMID:36395673. pexidartinib (plx3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. 2022-11-17 2023-08-14 mouse
Laifa Wang, Xueqin Wang, Ling Deng, Hui Zhang, Binsheng He, Wenyu Cao, Yanhui Cu. Pexidartinib (PLX3397) through restoring hippocampal synaptic plasticity ameliorates social isolation-induced mood disorders. International immunopharmacology. vol 113. issue Pt B. 2022-11-17. PMID:36395673. these findings suggest that inhibition of microglia in the hippocampus could ameliorate mood disorders in mice, providing a new perspective for the treatment of psychiatric disorders such as depression. 2022-11-17 2023-08-14 mouse
Wenjin Zou, Peilun Song, Weicong Lu, Robin Shao, Ruoxi Zhang, Suk-Yu Yau, Ti-Fei Yuan, Yaping Wang, Kangguang Li. Global hippocampus functional connectivity as a predictive neural marker for conversion to future mood disorder in unaffected offspring of bipolar disorder parents. Asian journal of psychiatry. vol 78. 2022-11-04. PMID:36332319. global hippocampus functional connectivity as a predictive neural marker for conversion to future mood disorder in unaffected offspring of bipolar disorder parents. 2022-11-04 2023-08-14 Not clear