| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Zeng Gao, Ru-Hua Ma, Zhao-Xia Zhan. miR-339 Promotes Hypoxia-Induced Neuronal Apoptosis and Impairs Cell Viability by Targeting FGF9/CACNG2 and Mediating MAPK Pathway in Ischemic Stroke. Frontiers in neurology. vol 11. 2020-09-28. PMID:32587563. |
mir-339 promotes hypoxia-induced neuronal apoptosis and impairs cell viability by targeting fgf9/cacng2 and mediating mapk pathway in ischemic stroke. |
2020-09-28 |
2023-08-13 |
Not clear |
| Lisda Amalia, Henny Anggraini Sadeli, Ida Parwati, Ahmad Rizal, Ramdan Panigor. Hypoxia-inducible factor-1α in acute ischemic stroke: neuroprotection for better clinical outcome. Heliyon. vol 6. issue 6. 2020-09-28. PMID:32637689. |
it can trigger apoptosis while stimulating angiogenesis process and decrease neurological deficit after an ischemic stroke. |
2020-09-28 |
2023-08-13 |
Not clear |
| Qi Gao, Yanfeng Wan. Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression. American journal of translational research. vol 12. issue 6. 2020-09-28. PMID:32655805. |
long noncoding rna malat1 regulates apoptosis in ischemic stroke by sponging mir-205-3p and modulating pten expression. |
2020-09-28 |
2023-08-13 |
Not clear |
| Qi Gao, Yanfeng Wan. Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression. American journal of translational research. vol 12. issue 6. 2020-09-28. PMID:32655805. |
ischemic stroke has been considered to be one of the major causes of disability worldwide which related to multiple pathological processes including apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Qi Gao, Yanfeng Wan. Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression. American journal of translational research. vol 12. issue 6. 2020-09-28. PMID:32655805. |
altogether, these results suggest that malat1 may suppress the apoptosis in ischemic stroke and function as a cerna for mir-205-3p to modulate pten expression. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jia Fan, Weiwei Xu, Shanji Nan, Meiji Chang, Yizhi Zhan. MicroRNA-384-5p Promotes Endothelial Progenitor Cell Proliferation and Angiogenesis in Cerebral Ischemic Stroke through the Delta-Likeligand 4-Mediated Notch Signaling Pathway. Cerebrovascular diseases (Basel, Switzerland). vol 49. issue 1. 2020-09-23. PMID:31927543. |
hence, the present study aimed at exploring the effect of mir-384-5p on proliferation, apoptosis, and angiogenesis of endothelial progenitor cells (epcs) in cerebral ischemic stroke and investigating the associated underlying mechanism. |
2020-09-23 |
2023-08-13 |
Not clear |
| Jiahui Li, Zhijie Liu, Liling Wang, Haiyan Xu, Yulin Wan. Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors. Bioscience reports. vol 39. issue 10. 2020-09-15. PMID:31652447. |
thousand and one kinase 1 protects mcao-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors. |
2020-09-15 |
2023-08-13 |
rat |
| Rui Jian, Min Yang, Fangyuan X. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31104315. |
hence, this study aims to explore the function of mcemp1 specifically in angiogenesis, neuronal proliferation, and apoptosis in rats with cerebral ischemic stroke. |
2020-09-14 |
2023-08-13 |
rat |
| Rui Jian, Min Yang, Fangyuan X. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31104315. |
after rats were transfected with mcemp1 shrna lentivirus, microvessel density (mvd), expression of mcemp1, caspase-3, and vascular endothelial growth factor (vegf), and neuronal proliferation and apoptosis were measured to explore the role of mcemp1 in cerebral ischemic stroke. |
2020-09-14 |
2023-08-13 |
rat |
| Rui Jian, Min Yang, Fangyuan X. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31104315. |
our study provides evidence that silenced mcemp1 could enhance angiogenesis and suppress neuronal apoptosis in rats with cerebral ischemic stroke, highlighting that mcemp1 silencing could serve as a therapeutic target for cerebral ischemic stroke treatment. |
2020-09-14 |
2023-08-13 |
rat |
| Yanlin Zhang, Yongjun Cao, Chunfeng Li. Autophagy and Ischemic Stroke. Advances in experimental medicine and biology. vol 1207. 2020-09-07. PMID:32671742. |
this chapter outlines the induction of basal autophagy, autophagy in neurons, and the crosstalk between autophagy, necrosis, and apoptosis that contributes to ischemic stroke. |
2020-09-07 |
2023-08-13 |
Not clear |
| Ya-Xiong Yong, Hua Yang, Jia Lian, Xiao-Wei Xu, Ke Han, Ming-Yi Hu, Hua-Cheng Wang, Lie-Min Zho. Up-regulated microRNA-199b-3p represses the apoptosis of cerebral microvascular endothelial cells in ischemic stroke through down-regulation of MAPK/ERK/EGR1 axis. Cell cycle (Georgetown, Tex.). vol 18. issue 16. 2020-08-28. PMID:31204565. |
up-regulated microrna-199b-3p represses the apoptosis of cerebral microvascular endothelial cells in ischemic stroke through down-regulation of mapk/erk/egr1 axis. |
2020-08-28 |
2023-08-13 |
mouse |
| Ya-Xiong Yong, Hua Yang, Jia Lian, Xiao-Wei Xu, Ke Han, Ming-Yi Hu, Hua-Cheng Wang, Lie-Min Zho. Up-regulated microRNA-199b-3p represses the apoptosis of cerebral microvascular endothelial cells in ischemic stroke through down-regulation of MAPK/ERK/EGR1 axis. Cell cycle (Georgetown, Tex.). vol 18. issue 16. 2020-08-28. PMID:31204565. |
in conclusion, these key results demonstrated up-regulated mir-199b-3p could protect mice against ischemic stroke by inhibiting the apoptosis of cmecs through blockade of mapk/erk/egr1 axis. |
2020-08-28 |
2023-08-13 |
mouse |
| Weijie Xie, Ting Zhu, Xi Dong, Fengwei Nan, Xiangbao Meng, Ping Zhou, Guibo Sun, Xiaobo Su. HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways. Biomolecules. vol 9. issue 10. 2020-08-12. PMID:31547018. |
ischemic stroke is a clinically common cerebrovascular disease whose main risks include necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion (i/r) injury. |
2020-08-12 |
2023-08-13 |
rat |
| S P Sergeeva, A A Savin, P F Litvitsky, A V Lyundup, I D Breslavich, Z Sh Manasov. [Neurohumoral response and Fas-ligand-induced apoptosis in peripheral blood of patients with acute ischemic stroke]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 120. issue 6. 2020-07-23. PMID:32678549. |
[neurohumoral response and fas-ligand-induced apoptosis in peripheral blood of patients with acute ischemic stroke]. |
2020-07-23 |
2023-08-13 |
Not clear |
| Wen-Zhen Shi, Ye Tian, Juan L. GCN2 suppression attenuates cerebral ischemia in mice by reducing apoptosis and endoplasmic reticulum (ER) stress through the blockage of FoxO3a-regulated ROS production. Biochemical and biophysical research communications. vol 516. issue 1. 2020-07-13. PMID:31255283. |
thereby, our findings indicated that gcn2 suppression alleviated apoptosis and ers in cerebral ischemia through reducing foxo3a-dependent ros production, illustrating that gcn2 could be a promising target for the therapeutic interventions in cerebral ischemic stroke. |
2020-07-13 |
2023-08-13 |
mouse |
| Zili Feng, Qian Sun, Wang Chen, Yu Bai, Daihua Hu, Xin Xi. The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review. Molecular medicine (Cambridge, Mass.). vol 25. issue 1. 2020-07-06. PMID:31864312. |
ischemic strokes can cause a sequence of detrimental events in patients, including increased permeability and dysfunction of the blood-brain barrier, brain edema, metabolic disturbance, endoplasmic reticulum stress, autophagy, oxidative stress, inflammation, neuron death and apoptosis, and cognitive impairment. |
2020-07-06 |
2023-08-13 |
Not clear |
| Anatoly B Uzdensk. Apoptosis regulation in the penumbra after ischemic stroke: expression of pro- and antiapoptotic proteins. Apoptosis : an international journal on programmed cell death. vol 24. issue 9-10. 2020-07-02. PMID:31256300. |
apoptosis regulation in the penumbra after ischemic stroke: expression of pro- and antiapoptotic proteins. |
2020-07-02 |
2023-08-13 |
human |
| Jing Zhao, Chao Lv, Qiuling Wu, Huawu Zeng, Xin Guo, Jian Yang, Saisai Tian, Weidong Zhan. Computational systems pharmacology reveals an antiplatelet and neuroprotective mechanism of Deng-Zhan-Xi-Xin injection in the treatment of ischemic stroke. Pharmacological research. vol 147. 2020-06-17. PMID:31348992. |
these target genes were further found to be associated with pathways involved in neuronal apoptosis in ischemic stroke, such as nf-κb signaling, tnf signaling, and pi3k-akt signaling. |
2020-06-17 |
2023-08-13 |
human |
| Zheyi Zhou, Changjun Lu, Shuhui Meng, Linglu Dun, Nannan Yin, Hongwei An, Hong Xu, Guocheng Liu, Yefeng Ca. Silencing of PTGS2 exerts promoting effects on angiogenesis endothelial progenitor cells in mice with ischemic stroke via repression of the NF-κB signaling pathway. Journal of cellular physiology. vol 234. issue 12. 2020-06-08. PMID:31222746. |
the objective of the current study is to investigate the effect of ptgs2 on proliferation, migration, angiogenesis and apoptosis of endothelial progenitor cells (epcs) in mice with ischemic stroke through the nf-κb signaling pathway. |
2020-06-08 |
2023-08-13 |
mouse |