| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Skovdal Rathleff, Kristian Kjær Petersen, Lars Arendt-Nielsen, Kristian Thorborg, Thomas Graven-Nielse. Impaired Conditioned Pain Modulation in Young Female Adults with Long-Standing Patellofemoral Pain: A Single Blinded Cross-Sectional Study. Pain medicine (Malden, Mass.). vol 17. issue 5. 2017-03-13. PMID:26814253. |
this study aimed to compare temporal summation of pain, conditioned pain modulation (cpm), and widespread hyperalgesia in young female adults with pfp and age-matched pain-free controls. |
2017-03-13 |
2023-08-13 |
Not clear |
| Kristian Kjær Petersen, Thomas Graven-Nielsen, Ole Simonsen, Mogens Berg Laursen, Lars Arendt-Nielse. Preoperative pain mechanisms assessed by cuff algometry are associated with chronic postoperative pain relief after total knee replacement. Pain. vol 157. issue 7. 2017-03-13. PMID:27331347. |
widespread hyperalgesia, facilitated temporal summation of pain (tsp), and impaired conditioned pain modulation (cpm) have been found in painful koa. |
2017-03-13 |
2023-08-13 |
Not clear |
| Franziska Labrenz, Adriane Icenhour, Marc Schlamann, Michael Forsting, Ulrike Bingel, Sigrid Elsenbruc. From Pavlov to pain: How predictability affects the anticipation and processing of visceral pain in a fear conditioning paradigm. NeuroImage. vol 130. 2017-01-12. PMID:26854560. |
conditioned pain-related fear may contribute to hyperalgesia and central sensitization, but this has not been tested for interoceptive, visceral pain. |
2017-01-12 |
2023-08-13 |
human |
| Franziska Labrenz, Adriane Icenhour, Marc Schlamann, Michael Forsting, Ulrike Bingel, Sigrid Elsenbruc. From Pavlov to pain: How predictability affects the anticipation and processing of visceral pain in a fear conditioning paradigm. NeuroImage. vol 130. 2017-01-12. PMID:26854560. |
in this functional magnetic resonance imaging study using painful rectal distensions as unconditioned stimuli (us), we addressed changes in the neural processing of pain during the acquisition of pain-related fear and subsequently tested if conditioned stimuli (cs) contribute to hyperalgesia and increased neural responses in pain-encoding regions. |
2017-01-12 |
2023-08-13 |
human |
| Franziska Labrenz, Adriane Icenhour, Marc Schlamann, Michael Forsting, Ulrike Bingel, Sigrid Elsenbruc. From Pavlov to pain: How predictability affects the anticipation and processing of visceral pain in a fear conditioning paradigm. NeuroImage. vol 130. 2017-01-12. PMID:26854560. |
these findings support that during fear conditioning, the ability to predict pain affects neural processing of visceral pain and alters the associative learning processes underlying the acquisition of predictive properties of cues signaling pain, but conditioned pain-related fear does not result in visceral hyperalgesia or central sensitization. |
2017-01-12 |
2023-08-13 |
human |
| Brian W LeBlanc, Theresa R Lii, Jian Jia Huang, Yu-Chieh Chao, Paul M Bowary, Brent S Cross, Margaret S Lee, Louis P Vera-Portocarrero, Carl Y Saa. T-type calcium channel blocker Z944 restores cortical synchrony and thalamocortical connectivity in a rat model of neuropathic pain. Pain. vol 157. issue 1. 2016-10-05. PMID:26683108. |
systemic z944 also reversed thermal hyperalgesia and conditioned place preference. |
2016-10-05 |
2023-08-13 |
rat |
| Karin Jensen, Irving Kirsch, Sara Odmalm, Ted J Kaptchuk, Martin Ingva. Classical conditioning of analgesic and hyperalgesic pain responses without conscious awareness. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 25. 2015-11-10. PMID:25979940. |
results demonstrate that conscious awareness of the cs is not required during either acquisition or extinction of conditioned analgesia or hyperalgesia. |
2015-11-10 |
2023-08-13 |
human |
| Tim P Jürgens, Alexander Sawatzki, Florian Henrich, Walter Magerl, Arne Ma. An improved model of heat-induced hyperalgesia--repetitive phasic heat pain causing primary hyperalgesia to heat and secondary hyperalgesia to pinprick and light touch. PloS one. vol 9. issue 6. 2015-10-07. PMID:24911787. |
quantitative sensory testing was done in eighteen healthy volunteers before and after repetitive heat pain stimuli (60 stimuli of 48°c for 6 s) to assess the impact of repetitive heat on somatosensory function in conditioned skin (primary hyperalgesia area) and in adjacent skin (secondary hyperalgesia area) as compared to an unconditioned mirror image control site. |
2015-10-07 |
2023-08-13 |
human |
| John V Roughan, Claire A Coulter, Paul A Flecknell, Huw D Thomas, Kenneth J Sufk. The conditioned place preference test for assessing welfare consequences and potential refinements in a mouse bladder cancer model. PloS one. vol 9. issue 8. 2015-04-11. PMID:25100208. |
we used conditioned place preference (cpp) testing, assessments of thermal hyperalgesia and behaviour to determine the likelihood that mbt-2 bladder cancer impacts negatively on mouse welfare, such as by causing pain. |
2015-04-11 |
2023-08-13 |
mouse |
| Deniz Bagdas, Pretal P Muldoon, Andy Z X Zhu, Rachel F Tyndale, M Imad Dama. Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. Neuropharmacology. vol 85. 2015-03-30. PMID:24859605. |
conditioned place preference (cpp) test was used to assess the appetitive reward-like properties and precipitated nicotine withdrawal to assess physical (somatic and hyperalgesia) and affective (anxiety-related behaviors) measures. |
2015-03-30 |
2023-08-13 |
mouse |
| Gonzalo Miguez, Mario A Laborda, Ralph R Mille. Classical conditioning and pain: conditioned analgesia and hyperalgesia. Acta psychologica. vol 145. 2014-05-16. PMID:24269884. |
classical conditioning and pain: conditioned analgesia and hyperalgesia. |
2014-05-16 |
2023-08-12 |
Not clear |
| Gonzalo Miguez, Mario A Laborda, Ralph R Mille. Classical conditioning and pain: conditioned analgesia and hyperalgesia. Acta psychologica. vol 145. 2014-05-16. PMID:24269884. |
specifically, the literature suggests that cues associated with stress can produce conditioned analgesia or conditioned hyperalgesia, depending on the properties of the conditioned stimulus (e.g., contextual cues and audiovisual cues vs. gustatory and olfactory cues, respectively) and the proprieties of the unconditioned stimulus (e.g., appetitive, aversive, or analgesic, respectively). |
2014-05-16 |
2023-08-12 |
Not clear |
| Hue Jung Park, Jennifer A Stokes, Elaine Pirie, James Skahen, Yuri Shtaerman, Tony L Yaks. Persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root ganglia activated transcription factor 3: the effects of gabapentin, ketorolac, and etanercept. Anesthesia and analgesia. vol 116. issue 1. 2013-02-15. PMID:23223118. |
persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root ganglia activated transcription factor 3: the effects of gabapentin, ketorolac, and etanercept. |
2013-02-15 |
2023-08-12 |
mouse |
| K J Jackson, J M McIntosh, D H Brunzell, S S Sanjakdar, M I Dama. The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal. The Journal of pharmacology and experimental therapeutics. vol 331. issue 2. 2009-11-30. PMID:19644040. |
we further measured physical (somatic signs and hyperalgesia) and affective [anxiety-related behavior and conditioned place aversion (cpa)] nicotine withdrawal behaviors after extended nicotine exposure. |
2009-11-30 |
2023-08-12 |
Not clear |
| Thomas Klein, Walter Magerl, Ursula Nickel, Hanns-Christian Hopf, Jürgen Sandkühler, Rolf-Detlef Treed. Effects of the NMDA-receptor antagonist ketamine on perceptual correlates of long-term potentiation within the nociceptive system. Neuropharmacology. vol 52. issue 2. 2007-04-10. PMID:17084865. |
these data support the concept that homotopic hyperalgesia to electrical stimulation of the conditioned pathway is a perceptual correlate of nmda-receptor sensitive homosynaptic ltp in the nociceptive system, e.g. |
2007-04-10 |
2023-08-12 |
human |
| Kevin D Beck, Michele Hsu, Xilu Jiao, Richard J Servatiu. Cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia. Pharmacology, biochemistry, and behavior. vol 84. issue 3. 2006-12-18. PMID:16844206. |
cholinergic overstimulation supports conditioned-facilitated startle but not conditioned hyperalgesia. |
2006-12-18 |
2023-08-12 |
rat |
| Thomas Klein, Walter Magerl, Hanns-Christian Hopf, Jürgen Sandkühler, Rolf-Detlef Treed. Perceptual correlates of nociceptive long-term potentiation and long-term depression in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 4. 2004-04-12. PMID:14749441. |
in summary, hfs and lfs stimulus protocols that induce ltp or ltd in spinal nociceptive pathways in animal experiments led to similar ltp- and ltd-like changes in human pain perception (long-term hyperalgesia or hypoalgesia) mediated by the conditioned pathway. |
2004-04-12 |
2023-08-12 |
human |
| M W Meagher, A R Ferguson, E D Crown, S McLemore, T E King, A N Sieve, J W Gra. Shock-induced hyperalgesia: IV. Generality. Journal of experimental psychology. Animal behavior processes. vol 27. issue 3. 2002-01-24. PMID:11497322. |
brief-moderate shock (3, 0.75 s, 1.0 ma) has opposite effects on different measures of pain, inducing antinociception on the tail-flick test while lowering vocalization thresholds to shock and heat (hyperalgesia) and enhancing fear conditioned by a gridshock unconditioned stimulus (us). |
2002-01-24 |
2023-08-12 |
Not clear |
| N Hirakawa, S A Tershner, H L Fields, B H Mannin. Bi-directional changes in affective state elicited by manipulation of medullary pain-modulatory circuitry. Neuroscience. vol 100. issue 4. 2001-01-18. PMID:11036220. |
hyperalgesia on the tail flick assay) and a negative affective state (as inferred from the production of conditioned place avoidance) in the conscious, freely moving rat. |
2001-01-18 |
2023-08-12 |
rat |
| T E King, E D Crown, A N Sieve, R L Joynes, J W Grau, M W Meaghe. Shock-induced hyperalgesia: evidence forebrain systems play an essential role. Behavioural brain research. vol 100. issue 1-2. 1999-07-28. PMID:10212051. |
prior work indicates that this hyperalgesia represents an unconditioned response and that it enhances the acquisition of both conditioned freezing and an avoidance response to thermal pain. |
1999-07-28 |
2023-08-12 |
rat |