Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
B Colagiuri, J Park, K Barnes, L Sharpe, R A Boakes, L Colloca, E J Livese. Pre-Exposure, But Not Overshadowing, Inhibits Nocebo Hyperalgesia. The journal of pain. vol 22. issue 7. 2021-09-23. PMID:33636369. |
we therefore tested whether two novel strategies - overshadowing (experiment 1) and pre-exposure (experiment 2) - could inhibit conditioned nocebo hyperalgesia. |
2021-09-23 |
2023-08-13 |
human |
B Colagiuri, J Park, K Barnes, L Sharpe, R A Boakes, L Colloca, E J Livese. Pre-Exposure, But Not Overshadowing, Inhibits Nocebo Hyperalgesia. The journal of pain. vol 22. issue 7. 2021-09-23. PMID:33636369. |
these findings provide novel evidence that pre-exposure, but not overshadowing, could be a cheap and effective way for mitigating the substantial harm caused by conditioned nocebo hyperalgesia in clinical settings. |
2021-09-23 |
2023-08-13 |
human |
B Colagiuri, J Park, K Barnes, L Sharpe, R A Boakes, L Colloca, E J Livese. Pre-Exposure, But Not Overshadowing, Inhibits Nocebo Hyperalgesia. The journal of pain. vol 22. issue 7. 2021-09-23. PMID:33636369. |
our study found novel evidence that pre-exposing treatment cues without pain, but not overshadowing them with other cues, has the capacity to inhibit conditioned nocebo hyperalgesia. |
2021-09-23 |
2023-08-13 |
human |
Elena Neumann, Laura Küpfer, Hanns Ulrich Zeilhofe. The α2/α3GABAA receptor modulator TPA023B alleviates not only the sensory but also the tonic affective component of chronic pain in mice. Pain. vol 162. issue 2. 2021-05-19. PMID:32773599. |
in neuropathic mice with a chronic constriction injury of the sciatic nerve, tpa023b not only reversed hyperalgesia to tactile and heat stimuli but also was highly effective in the conditioned place preference test. |
2021-05-19 |
2023-08-13 |
mouse |
Marcus M Weera, Allyson L Schreiber, Elizabeth M Avegno, Nicholas W Gilpi. The role of central amygdala corticotropin-releasing factor in predator odor stress-induced avoidance behavior and escalated alcohol drinking in rats. Neuropharmacology. vol 166. 2021-04-02. PMID:32028150. |
we also showed previously that systemic antagonism of corticotropin-releasing factor-1 receptors (crfr1) reduced escalation of operant alcohol sa in rats not indexed for avoidance, that corticotropin-releasing factor (crf) infusions into the central amygdala (cea) produced conditioned place avoidance in stress-naïve rats, and that intra-cea infusion of a crfr1 antagonist reduced hyperalgesia in avoiders. |
2021-04-02 |
2023-08-13 |
rat |
Kosaku Aoyagi, Jianghua He, Andrea L Nicol, Daniel J Clauw, Patricia M Kluding, Stephen Jernigan, Neena K Sharm. A Subgroup of Chronic Low Back Pain Patients With Central Sensitization. The Clinical journal of pain. vol 35. issue 11. 2020-10-20. PMID:31408011. |
the major features of cs including widespread hyperalgesia and dysfunction of the descending inhibitory pathways can be identified by pressure pain threshold (ppt) and conditioned pain modulation (cpm) tests. |
2020-10-20 |
2023-08-13 |
Not clear |
Ryan B Griggs, Don E Laird, Renee R Donahue, Weisi Fu, Bradley K Taylo. Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:29270106. |
methylglyoxal produced conditioned place avoidance (cpa) (a measure of affective pain), dose-dependent licking and lifting nociceptive behaviors, hyperalgesia to heat and mechanical stimulation, and p-erk in the spinal cord dorsal horn. |
2020-10-01 |
2023-08-13 |
mouse |
Przemysław Bąbe. Classical Conditioning as a Distinct Mechanism of Placebo Effects. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31293460. |
however, the existing body of evidence is limited to classically conditioned placebo effects in pain, that is, placebo analgesia and nocebo hyperalgesia. |
2020-09-30 |
2023-08-13 |
human |
Shannon N Tansley, Leigh C Macintyre, Laura Diamond, Susana G Sotocinal, Nicole George, Lee Meluban, Jean-Sebastien Austin, Terence J Coderre, Loren J Martin, Jeffrey S Mogi. Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. Pain. vol 160. issue 4. 2019-06-26. PMID:30681982. |
conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. |
2019-06-26 |
2023-08-13 |
mouse |
Sinéad Holden, Christian Lund Straszek, Michael Skovdal Rathleff, Kristian Kjær Petersen, Ewa M Roos, Thomas Graven-Nielse. Young females with long-standing patellofemoral pain display impaired conditioned pain modulation, increased temporal summation of pain, and widespread hyperalgesia. Pain. vol 159. issue 12. 2019-02-19. PMID:30074593. |
young females with long-standing patellofemoral pain display impaired conditioned pain modulation, increased temporal summation of pain, and widespread hyperalgesia. |
2019-02-19 |
2023-08-13 |
Not clear |
Yiheng Tu, Joel Park, Seppo P Ahlfors, Sheraz Khan, Natalia Egorova, Courtney Lang, Jin Cao, Jian Kon. A neural mechanism of direct and observational conditioning for placebo and nocebo responses. NeuroImage. vol 184. 2019-02-04. PMID:30296557. |
classical theories suggest placebo analgesia and nocebo hyperalgesia are based on expectation and conditioned experience. |
2019-02-04 |
2023-08-13 |
Not clear |
I Coppieters, R De Pauw, K Caeyenberghs, D Lenoir, K DeBlaere, E Genbrugge, M Meeus, B Cagni. Differences in white matter structure and cortical thickness between patients with traumatic and idiopathic chronic neck pain: Associations with cognition and pain modulation? Human brain mapping. vol 39. issue 4. 2018-12-17. PMID:29327392. |
next, cognitive performance, and cs encompassing distant hyperalgesia and conditioned pain modulation (cpm) efficacy were examined. |
2018-12-17 |
2023-08-13 |
Not clear |
Kristian K Petersen, Lars Arendt-Nielsen, Sara Finocchietti, Rogerio P Hirata, Ole Simonsen, Mogens B Laursen, Thomas Graven-Nielse. Age Interactions on Pain Sensitization in Patients With Severe Knee Osteoarthritis and Controls. The Clinical journal of pain. vol 33. issue 12. 2018-06-18. PMID:28277434. |
widespread pressure hyperalgesia, facilitated temporal summation of pain (tsp), and impaired conditioned pain modulation (cpm) have been found in knee osteoarthritis (koa) patients compared with controls and these parameters have further been suggested to be altered in the elderly. |
2018-06-18 |
2023-08-13 |
Not clear |
Eder Gambeta, Caroline Machado Kopruszinski, Renata Cristiane Dos Reis, Janaina Menezes Zanoveli, Juliana Geremias Chichorr. Facial pain and anxiety-like behavior are reduced by pregabalin in a model of facial carcinoma in rats. Neuropharmacology. vol 125. 2018-06-12. PMID:28778832. |
on day 6 after inoculation spontaneous facial grooming and conditioned place preference were assessed as non-evoked pain measurements and facial mechanical hyperalgesia were assessed 3 and 6 days after tumor cells inoculation. |
2018-06-12 |
2023-08-13 |
rat |
Keren Grinberg, Michal Granot, Lior Lowenstein, Liora Abramov, Irit Weissman-Foge. A common pronociceptive pain modulation profile typifying subgroups of chronic pelvic pain syndromes is interrelated with enhanced clinical pain. Pain. vol 158. issue 6. 2018-03-07. PMID:28178074. |
we found a similar pronociceptive pain profile in the 2 subgroups of cpps-enhanced facilitation (ie, hyperalgesia in the referred body area [p < 0.001]) and inefficient inhibition (ie, reduced conditioned pain modulation [p < 0.001] that were associated with both enhanced pain ratings evoked during trigger point examination [p < 0.037]) and higher brief pain inventory ratings (p = 0.002). |
2018-03-07 |
2023-08-13 |
Not clear |
Michael Skovdal Rathleff, Camilla Rams Rathleff, Aoife Stephenson, Rebecca Mellor, Mark Matthews, Kay Crossley, Bill Vicenzin. Adults with patellofemoral pain do not exhibit manifestations of peripheral and central sensitization when compared to healthy pain-free age and sex matched controls - An assessor blinded cross-sectional study. PloS one. vol 12. issue 12. 2018-01-04. PMID:29220355. |
the aims of this study were to study conditioned pain modulation (cpm) and wide-spread hyperalgesia in adults with pfp. |
2018-01-04 |
2023-08-13 |
human |
Victoria J Madden, Daniel S Harvie, Romy Parker, Karin B Jensen, Johan W S Vlaeyen, G Lorimer Moseley, Tasha R Stanto. Can Pain or Hyperalgesia Be a Classically Conditioned Response in Humans? A Systematic Review and Meta-Analysis. Pain medicine (Malden, Mass.). vol 17. issue 6. 2017-09-29. PMID:26814278. |
can pain or hyperalgesia be a classically conditioned response in humans? |
2017-09-29 |
2023-08-13 |
Not clear |
James E Zadina, Mark R Nilges, Jenny Morgenweck, Xing Zhang, Laszlo Hackler, Melita B Fasol. Endomorphin analog analgesics with reduced abuse liability, respiratory depression, motor impairment, tolerance, and glial activation relative to morphine. Neuropharmacology. vol 105. 2017-06-22. PMID:26748051. |
at doses providing equal or greater antinociception than morphine in the rat, the analogs showed reduced a) respiratory depression, b) impairment of motor coordination, c) tolerance and hyperalgesia, d) glial p38/cgrp/p2x7 receptor signaling, and e) reward/abuse potential in both conditioned place preference and self-administration tests. |
2017-06-22 |
2023-08-13 |
rat |
Michael Skovdal Rathleff, Kristian Kjær Petersen, Lars Arendt-Nielsen, Kristian Thorborg, Thomas Graven-Nielse. Impaired Conditioned Pain Modulation in Young Female Adults with Long-Standing Patellofemoral Pain: A Single Blinded Cross-Sectional Study. Pain medicine (Malden, Mass.). vol 17. issue 5. 2017-03-13. PMID:26814253. |
this study aimed to compare temporal summation of pain, conditioned pain modulation (cpm), and widespread hyperalgesia in young female adults with pfp and age-matched pain-free controls. |
2017-03-13 |
2023-08-13 |
Not clear |
Kristian Kjær Petersen, Thomas Graven-Nielsen, Ole Simonsen, Mogens Berg Laursen, Lars Arendt-Nielse. Preoperative pain mechanisms assessed by cuff algometry are associated with chronic postoperative pain relief after total knee replacement. Pain. vol 157. issue 7. 2017-03-13. PMID:27331347. |
widespread hyperalgesia, facilitated temporal summation of pain (tsp), and impaired conditioned pain modulation (cpm) have been found in painful koa. |
2017-03-13 |
2023-08-13 |
Not clear |