| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zeinab Jaleh, Behnaz Rahimi, Aidin Shahrezaei, Maryam Sohani, Jacqueline Sagen, Farinaz Nasirinezha. Exploring the Therapeutic Potential of Mesenchymal Stem Cells-derived conditioned medium: An In-depth Analysis of Pain Alleviation, Spinal CCL2 Levels, and Oxidative Stress. Cell biochemistry and biophysics. 2024-07-20. PMID:39031248. |
the behavioral experiments showed a decrease in mechanical hyperalgesia and cold allodynia in the group receiving conditioned medium compared to the injury group and the control medium group. |
2024-07-20 |
2024-07-24 |
rat |
| Biya Tang, Evan Livesey, Ben Colagiur. The downside to choice: instrumental control increases conditioned nocebo hyperalgesia. Pain. 2024-05-06. PMID:38709490. |
the downside to choice: instrumental control increases conditioned nocebo hyperalgesia. |
2024-05-06 |
2024-05-08 |
human |
| Biya Tang, Evan Livesey, Ben Colagiur. The downside to choice: instrumental control increases conditioned nocebo hyperalgesia. Pain. 2024-05-06. PMID:38709490. |
this study investigated the impact of choice on conditioned nocebo hyperalgesia using a well-established electrocutaneous pain paradigm where increases in noxious stimulation were surreptitiously paired with the activation of a sham device. |
2024-05-06 |
2024-05-08 |
human |
| Jing Chen, Yuan Gao, Shu-Ting Bao, Ying-Di Wang, Tao Jia, Cui Yin, Cheng Xiao, Chunyi Zho. Insula-amygdala and insula-thalamus pathways are involved in comorbid chronic pain and depression-like behavior in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-07. PMID:38453468. |
optogenetic activation of pic neurons induced hyperalgesia and conditioned place aversion in naïve mice, whereas inhibition of these neurons led to analgesia, conditioned place preference (cpp), and antidepressant effect in both naïve and sni mice. |
2024-03-07 |
2024-03-10 |
mouse |
| Gabriele Bertotti, Juan Ignacio Elizagaray-García, Jaime Rodríguez-Vico, Alfonso Gil-Martíne. Hyperalgesia, Increased Temporal Summation and Impaired Inhibitory Mechanisms in Episodic and Chronic Cluster Headache: An Observational Study. Biomedicines. vol 12. issue 2. 2024-02-24. PMID:38397976. |
the objective of this study was (1) to compare hyperalgesia signs, temporal summation and conditioned pain modulation among episodic (ech) and chronic ch (cch) patients and controls, (2) to compare these factors between sides in the patient groups and (3) to compare the psychophysical variables between the groups. |
2024-02-24 |
2024-02-26 |
human |
| Andrew D Vigotsky, Olivia Cong, Camila B Pinto, Joana Barroso, Jennifer Perez, Kristian Kjaer Petersen, Lars Arendt-Nielsen, Kevin Hardt, David Manning, A Vania Apkarian, Paulo Branc. Mechanical hyperalgesia and neuropathic pain qualities impart risk for chronic postoperative pain after total knee replacement. medRxiv : the preprint server for health sciences. 2024-01-31. PMID:38293074. |
qst parameters included pressure pain pressure threshold (ppt), pain tolerance threshold (ptt), conditioned pain modulation (cpm), and temporal summation (ts) using cuff algometry, alongside mechanical hyperalgesia, and mechanical temporal summation to repeated pinprick stimulation. |
2024-01-31 |
2024-02-02 |
Not clear |
| Ryan Patel, Joseph L Taylor, Anthony H Dickenson, Stephen B McMahon, Kirsty Banniste. A back-translational study of descending interactions with the induction of hyperalgesia by high-frequency electrical stimulation in rat and human. Pain. 2024-01-10. PMID:38198231. |
to investigate the impact of hfs-induced hyperalgesia on pain and nociception in perception and neural terms, respectively, and to explore the impact of descending inhibitory pathway activation on the development of hfs-induced hyperalgesia, we performed parallel studies utilising identical stimuli to apply hfs concurrent to (1) a conditioned pain modulation paradigm during psychophysical testing in healthy humans or (2) a diffuse noxious inhibitory controls paradigm during in vivo electrophysiological recording of spinal neurones in healthy anaesthetised rats. |
2024-01-10 |
2024-01-13 |
human |
| Tamara Morris, Jessica A Cucinello-Ragland, Taylor J Marks, Kayla Prevost, John F Glenn, Gregory J Davenport, Scott Edwards, Peter J Winsaue. Distinct antinociceptive and conditioned behavioral effects are produced by individual cannabinoids and a cannabis-derived mixture. Pharmacology, biochemistry, and behavior. 2023-12-21. PMID:38128766. |
in summary, while nepe14 significantly reduced cfa-induced hyperalgesia, it was more similar to cbd than Δ9-thc, Δ8-thc, and cp for significantly reducing thermal nociception and disrupting conditioned behavior. |
2023-12-21 |
2023-12-24 |
rat |
| Kayleigh De Meulemeester, Mira Meeus, Robby De Pauw, Barbara Cagnie, Hannah Keppler, Dorine Lenoi. Suffering from chronic tinnitus, chronic neck pain, or both: Does it impact the presence of signs and symptoms of central sensitization? PloS one. vol 18. issue 8. 2023-08-24. PMID:37616265. |
differences in signs and symptoms of central sensitization were examined using the self-report central sensitization inventory and qst protocol (local and distant mechanical and heat hyperalgesia, conditioned pain modulation). |
2023-08-24 |
2023-09-07 |
Not clear |
| Jürg Schliessbach, Andreas Siegenthaler, Thomas Graven-Nielsen, Lars Arendt-Nielsen, Michele Curatol. Effects of conditioned pain modulation on Capsaicin-induced spreading muscle hyperalgesia in humans. Scandinavian journal of pain. 2023-06-09. PMID:37293789. |
effects of conditioned pain modulation on capsaicin-induced spreading muscle hyperalgesia in humans. |
2023-06-09 |
2023-08-14 |
Not clear |
| Beatriz M DeJesus, Ingrid Kyelli L Rodrigues, Isabela F Azevedo-Santos, Josimari M DeSantan. Effect of transcutaneous electrical nerve stimulation on pain-related quantitative sensory tests in chronic musculoeskeletal pain and acute experimental pain: systematic review and meta-analysis. The journal of pain. 2023-04-08. PMID:37030583. |
thirty-four studies assessed pain intensity; 24 studies investigated hyperalgesia; temporal summation was only evaluated in two studies; and conditioned pain modulation was not observed in the included studies. |
2023-04-08 |
2023-08-14 |
Not clear |
| Damien C Boorman, Kevin A Kea. Learning Pain in Context: Response-Conditioned Placebo Analgesia and Nocebo Hyperalgesia in Male Rats with Chronic Neuropathic Pain. Physiology & behavior. 2023-02-11. PMID:36773736. |
this study sought to elicit both conditioned placebo analgesia and conditioned nocebo hyperalgesia in rats with chronic neuropathic pain using non-pharmacological, contextual conditioning approaches, similar to those used in humans. |
2023-02-11 |
2023-08-14 |
rat |
| Nadia Kriek, Cecile C de Vos, Johannes G Groeneweg, Sara J Baart, Frank J P M Huyge. Allodynia, Hyperalgesia, (Quantitative) Sensory Testing and Conditioned Pain Modulation in Patients With Complex Regional Pain Syndrome Before and After Spinal Cord Stimulation Therapy. Neuromodulation : journal of the International Neuromodulation Society. 2022-09-01. PMID:36050204. |
allodynia, hyperalgesia, (quantitative) sensory testing and conditioned pain modulation in patients with complex regional pain syndrome before and after spinal cord stimulation therapy. |
2022-09-01 |
2023-08-14 |
Not clear |
| Nadia Kriek, Cecile C de Vos, Johannes G Groeneweg, Sara J Baart, Frank J P M Huyge. Allodynia, Hyperalgesia, (Quantitative) Sensory Testing and Conditioned Pain Modulation in Patients With Complex Regional Pain Syndrome Before and After Spinal Cord Stimulation Therapy. Neuromodulation : journal of the International Neuromodulation Society. 2022-09-01. PMID:36050204. |
therefore, this study investigated the effect of scs on allodynia, hyperalgesia, electrical quantitative sensory testing (qst) parameters, and conditioned pain modulation (cpm) effect. |
2022-09-01 |
2023-08-14 |
Not clear |
| Tian-Zhi Guo, Xiaoyou Shi, Wen-Wu Li, Tzuping Wei, Peyman Sahbaie, J David Clark, Wade S Kinger. Pronociceptive autoantibodies in the spinal cord mediate nociceptive sensitization, loss of function, and spontaneous pain in the lumbar disk puncture model of chronic back pain. Pain. 2022-08-17. PMID:35976729. |
wild-type dp mice developed 24 weeks of hindpaw mechanical allodynia and hyperalgesia, grip weakness, and a conditioned place preference response indicative of spontaneous pain, but pain responses were attenuated or absent in mumt dp mice. |
2022-08-17 |
2023-08-14 |
mouse |
| Jessica A Peterson, Cameron Lohman, Rebecca D Larson, Michael G Bemben, Christopher D Blac. Body Composition does not influence Conditioned Pain Modulation and Exercise Induced Hyperalgesia in Healthy Males and Females. European journal of pain (London, England). 2022-07-08. PMID:35802068. |
body composition does not influence conditioned pain modulation and exercise induced hyperalgesia in healthy males and females. |
2022-07-08 |
2023-08-14 |
Not clear |
| Daniel S Harvie, Eva Y Poolman, Victoria J Madden, Nick A Olthof, Michel W Coppieter. Classically conditioned modulation of pain depends on stimulus intensity. Experimental brain research. 2022-02-11. PMID:35147723. |
this is termed classically conditioned hyperalgesia. |
2022-02-11 |
2023-08-13 |
human |
| Daniel S Harvie, Eva Y Poolman, Victoria J Madden, Nick A Olthof, Michel W Coppieter. Classically conditioned modulation of pain depends on stimulus intensity. Experimental brain research. 2022-02-11. PMID:35147723. |
further attention is needed to comprehensively understand the variables that impact classically conditioned hyperalgesia. |
2022-02-11 |
2023-08-13 |
human |
| Dongman Chao, Christina M Mecca, Guoliang Yu, Ian Segel, Michael S Gold, Quinn H Hogan, Bin Pa. Dorsal root ganglion stimulation of injured sensory neurons in rats rapidly eliminates their spontaneous activity and relieves spontaneous pain. Pain. vol 162. issue 12. 2021-11-20. PMID:33990112. |
ganglion field stimulation delivered at the l5 dorsal root ganglion blocked mechanical hyperalgesia behavior, mechanical allodynia, and ongoing spontaneous pain indicated by conditioned place preference, whereas gfs at l4 blocked evoked pain behavior but not spontaneous pain. |
2021-11-20 |
2023-08-13 |
rat |
| Shervin Vencatachellum, Marian van der Meulen, Dimitri M L Van Ryckeghem, Stefaan Van Damme, Claus Vögel. Brief mindfulness training can mitigate the influence of prior expectations on pain perception. European journal of pain (London, England). vol 25. issue 9. 2021-10-27. PMID:34101937. |
specifically, we aimed to investigate whether the instructed use of a mindfulness compared to a suppression strategy differentially modulates the magnitudes of conditioned hypoalgesia and hyperalgesia. |
2021-10-27 |
2023-08-13 |
Not clear |