| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sergi Borrego-Écija, Joana Morgado, Leire Palencia-Madrid, Oriol Grau-Rivera, Ramón Reñé, Isabel Hernández, Consuelo Almenar, Mircea Balasa, Anna Antonell, José Luis Molinuevo, Albert Lladó, Marian Martínez de Pancorbo, Ellen Gelpi, Raquel Sánchez-Vall. Frontotemporal Dementia Caused by the P301L Mutation in the MAPT Gene: Clinicopathological Features of 13 Cases from the Same Geographical Origin in Barcelona, Spain. Dementia and geriatric cognitive disorders. vol 44. issue 3-4. 2018-10-09. PMID:28934750. |
frontotemporal dementia caused by the p301l mutation in the mapt gene: clinicopathological features of 13 cases from the same geographical origin in barcelona, spain. |
2018-10-09 |
2023-08-13 |
Not clear |
| Pawel Tacik, Michael A DeTure, Yari Carlomagno, Wen-Lang Lin, Melissa E Murray, Matthew C Baker, Keith A Josephs, Bradley F Boeve, Zbigniew K Wszolek, Neill R Graff-Radford, Joseph E Parisi, Leonard Petrucelli, Rosa Rademakers, Richard S Isaacson, Kenneth M Heilman, Ronald C Petersen, Dennis W Dickson, Naomi Kour. FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G. Brain pathology (Zurich, Switzerland). vol 27. issue 5. 2018-08-20. PMID:27529406. |
mutations in microtubule-associated protein tau gene (mapt) cause frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17). |
2018-08-20 |
2023-08-13 |
Not clear |
| Ghazaleh Eskandari-Sedighi, Nathalie Daude, Hristina Gapeshina, David W Sanders, Razieh Kamali-Jamil, Jing Yang, Beipei Shi, Holger Wille, Bernardino Ghetti, Marc I Diamond, Christopher Janus, David Westawa. The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition. Molecular neurodegeneration. vol 12. issue 1. 2018-06-08. PMID:28978354. |
mapt mutations cause neurodegenerative diseases such as frontotemporal dementia but, strikingly, patients with the same mutation may have different clinical phenotypes. |
2018-06-08 |
2023-08-13 |
Not clear |
| Xiang-Qian Che, Qian-Hua Zhao, Yue Huang, Xia Li, Ru-Jing Ren, Sheng-Di Chen, Gang Wang, Qi-Hao Gu. Genetic Features of MAPT, GRN, C9orf72 and CHCHD10 Gene Mutations in Chinese Patients with Frontotemporal Dementia. Current Alzheimer research. vol 14. issue 10. 2018-05-29. PMID:28462717. |
genetic features of mapt, grn, c9orf72 and chchd10 gene mutations in chinese patients with frontotemporal dementia. |
2018-05-29 |
2023-08-13 |
Not clear |
| Xiang-Qian Che, Qian-Hua Zhao, Yue Huang, Xia Li, Ru-Jing Ren, Sheng-Di Chen, Gang Wang, Qi-Hao Gu. Genetic Features of MAPT, GRN, C9orf72 and CHCHD10 Gene Mutations in Chinese Patients with Frontotemporal Dementia. Current Alzheimer research. vol 14. issue 10. 2018-05-29. PMID:28462717. |
mutations in microtubule associated protein tau (mapt), progranulin (grn), chromosome 9 open-reading frame 72 (c9orf72) and chchd10 genes have been reported causing frontotemporal dementia (ftd) in different populations. |
2018-05-29 |
2023-08-13 |
Not clear |
| P Tacik, M Sanchez-Contreras, M DeTure, M E Murray, R Rademakers, O A Ross, Z K Wszolek, J E Parisi, D S Knopman, R C Petersen, D W Dickso. Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy. Neuropathology and applied neurobiology. vol 43. issue 3. 2018-04-11. PMID:27859539. |
clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) due to microtubule-associated protein tau (mapt) p.p301l mutation, including a patient with globular glial tauopathy. |
2018-04-11 |
2023-08-13 |
Not clear |
| P Tacik, M Sanchez-Contreras, M DeTure, M E Murray, R Rademakers, O A Ross, Z K Wszolek, J E Parisi, D S Knopman, R C Petersen, D W Dickso. Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy. Neuropathology and applied neurobiology. vol 43. issue 3. 2018-04-11. PMID:27859539. |
the p.p301l mutation in microtubule-associated protein tau (mapt) is a common cause of frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17). |
2018-04-11 |
2023-08-13 |
Not clear |
| Cheng-Cheng Zhang, Jun-Xia Zhu, Yu Wan, Lin Tan, Hui-Fu Wang, Jin-Tai Yu, Lan Ta. Meta-analysis of the association between variants in MAPT and neurodegenerative diseases. Oncotarget. vol 8. issue 27. 2018-03-29. PMID:28402959. |
microtubule-associated protein tau (mapt) gene is compelling among the susceptibility genes of neurodegenerative diseases which include alzheimer's disease (ad), parkinson's disease (pd), progressive supranuclear palsy (psp), corticobasal degeneration (cbd), frontotemporal dementia (ftd) and amyotrophic lateral sclerosis (als). |
2018-03-29 |
2023-08-13 |
Not clear |
| Noemí Esteras, Jonathan D Rohrer, John Hardy, Selina Wray, Andrey Y Abramo. Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration. Redox biology. vol 12. 2018-03-20. PMID:28319892. |
the 10+16 intronic mutation in mapt gene, encoding tau, causes frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17), by altering the splicing of the gene and inducing an increase in the production of 4r tau isoforms, which are more prone to aggregation. |
2018-03-20 |
2023-08-13 |
Not clear |
| Robert Haussmann, Marek Wysocki, Moritz D Brandt, Andreas Hermann, Markus Doni. MAPT mutation associated with frontotemporal dementia and parkinsonism (FTDP-17). International psychogeriatrics. vol 29. issue 5. 2018-02-26. PMID:27905268. |
mapt mutation associated with frontotemporal dementia and parkinsonism (ftdp-17). |
2018-02-26 |
2023-08-13 |
Not clear |
| Lin Sun, Kathryn Chen, Xia Li, Shifu Xia. Rapidly Progressive Frontotemporal Dementia Associated with MAPT Mutation G389R. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27802239. |
rapidly progressive frontotemporal dementia associated with mapt mutation g389r. |
2018-02-22 |
2023-08-13 |
Not clear |
| David M A Mann, Julie S Snowde. Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype. Brain pathology (Zurich, Switzerland). vol 27. issue 6. 2018-01-26. PMID:28100023. |
there are three major associated clinical syndromes, behavioral variant frontotemporal dementia (bvftd), semantic dementia (sd) and progressive non-fluent aphasia (pnfa); three principal histologies, involving tau, tdp-43 and fus proteins; and mutations in three major genes, mapt, grn and c9orf72, along with several other less common gene mutations. |
2018-01-26 |
2023-08-13 |
Not clear |
| João Massano, Miguel Leão, Carolina Garret. [Investigation of Genetic Etiology in Neurodegenerative Dementias: Recommendations from the Centro Hospitalar São João Neurogenetics Group]. Acta medica portuguesa. vol 29. issue 10. 2018-01-23. PMID:28103467. |
frontotemporal dementia may be caused by mutations in several genes such as c9orf72, pgrn, mapt, tbk1, vcp, sqstm1, and ubqln2. |
2018-01-23 |
2023-08-13 |
Not clear |
| Natakarn Nimsanor, Narisorn Kitiyanant, Ulla Poulsen, Mikkel A Rasmussen, Christian Clausen, Ulrike A Mau-Holzmann, Jørgen E Nielsen, Troels T Nielsen, Poul Hyttel, Bjørn Holst, Benjamin Schmi. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene. Stem cell research. vol 17. issue 3. 2018-01-22. PMID:27789409. |
generation of an isogenic, gene-corrected ipsc line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a p301l mutation in the microtubule associated protein tau (mapt) gene. |
2018-01-22 |
2023-08-13 |
Not clear |
| Natakarn Nimsanor, Ida Jørring, Mikkel A Rasmussen, Christian Clausen, Ulrike A Mau-Holzmann, Narisorn Kitiyanant, Jørgen E Nielsen, Troels T Nielsen, Poul Hyttel, Bjørn Holst, Benjamin Schmi. Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia. Stem cell research. vol 17. issue 3. 2018-01-22. PMID:27789411. |
induced pluripotent stem cells (ipscs) derived from a symptomatic carrier of a s305i mutation in the microtubule-associated protein tau (mapt)-gene causing frontotemporal dementia. |
2018-01-22 |
2023-08-13 |
Not clear |
| Natakarn Nimsanor, Ulla Poulsen, Mikkel A Rasmussen, Christian Clausen, Ulrike A Mau-Holzmann, Jørgen E Nielsen, Troels T Nielsen, Poul Hyttel, Bjørn Holst, Benjamin Schmi. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene. Stem cell research. vol 17. issue 3. 2018-01-22. PMID:27934586. |
generation of an isogenic, gene-corrected ipsc line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an r406w mutation in the microtubule associated protein tau (mapt) gene. |
2018-01-22 |
2023-08-13 |
Not clear |
| Carol Dobson-Stone, John B J Kwo. Finding MAPT Mutations in Frontotemporal Dementia and Other Tauopathies. Methods in molecular biology (Clifton, N.J.). vol 1523. 2018-01-22. PMID:27975259. |
finding mapt mutations in frontotemporal dementia and other tauopathies. |
2018-01-22 |
2023-08-13 |
human |
| Md Helal U Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna Karydas, Michael D Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L Miller, Fen-Biao Ga. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem cell reports. vol 7. issue 3. 2017-11-21. PMID:27594586. |
mmp-9 and mmp-2 contribute to neuronal cell death in ipsc models of frontotemporal dementia with mapt mutations. |
2017-11-21 |
2023-08-13 |
human |
| Md Helal U Biswas, Sandra Almeida, Rodrigo Lopez-Gonzalez, Wenjie Mao, Zhijun Zhang, Anna Karydas, Michael D Geschwind, Jacek Biernat, Eva-Maria Mandelkow, Kensuke Futai, Bruce L Miller, Fen-Biao Ga. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem cell reports. vol 7. issue 3. 2017-11-21. PMID:27594586. |
how mutations in the microtubule-associated protein tau (mapt) gene cause frontotemporal dementia (ftd) remains poorly understood. |
2017-11-21 |
2023-08-13 |
human |
| Leonel T Takada, Valeria S Bahia, Henrique C Guimarães, Thais V M M Costa, Thiago C Vale, Roberta D Rodriguez, Fabio H G Porto, João C B Machado, Rogério G Beato, Karolina G Cesar, Jerusa Smid, Camila F Nascimento, Lea T Grinberg, Sonia M D Brucki, Jessica R Maximino, Sarah T Camargos, Gerson Chadi, Paulo Caramelli, Ricardo Nitrin. GRN and MAPT Mutations in 2 Frontotemporal Dementia Research Centers in Brazil. Alzheimer disease and associated disorders. vol 30. issue 4. 2017-11-16. PMID:27082848. |
grn and mapt mutations in 2 frontotemporal dementia research centers in brazil. |
2017-11-16 |
2023-08-13 |
Not clear |