Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Shengming Yin, Zhuo Guan, Yiyuan Tang, Jie Zhao, Jaushyong Hong, Wanqin Zhan. Abnormal expression of epilepsy-related gene ERG1/NSF in the spontaneous recurrent seizure rats with spatial learning memory deficits induced by kainic acid. Brain research. vol 1053. issue 1-2. 2005-10-27. PMID:16039622. |
to explore whether spatial learning memory deficits are relevant to srs and whether hippocampal nsf expression is altered by srs, we used the kainic acid (ka)-induced epilepsy animal model. |
2005-10-27 |
2023-08-12 |
rat |
Laura Costantin, Yuri Bozzi, Cristina Richichi, Alessandro Viegi, Flavia Antonucci, Marcella Funicello, Marco Gobbi, Tiziana Mennini, Ornella Rossetto, Cesare Montecucco, Lamberto Maffei, Annamaria Vezzani, Matteo Cale. Antiepileptic effects of botulinum neurotoxin E. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 8. 2005-10-26. PMID:15728834. |
we conclude that bont/e delivery to the hippocampus is both antiictal and antiepileptogenic in experimental models of epilepsy. |
2005-10-26 |
2023-08-12 |
rat |
D S Roberts, Y H Raol, S Bandyopadhyay, I V Lund, E C Budreck, M A Passini, M J Passini, J H Wolfe, A R Brooks-Kayal, S J Russe. Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABA(A) receptor alpha4 subunit expression. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 33. 2005-10-25. PMID:16091474. |
given that egr3 knockout mice display approximately 50% less gabra4 mrnas in the hippocampus and that increases in alpha4 and egr3 mrnas in response to pilocarpine-induced status epilepticus are accompanied by increased binding of egr3 to gabra4 in dentate granule cells, our findings support a role for egr3 as a major regulator of gabra4 in developing neurons and in epilepsy. |
2005-10-25 |
2023-08-12 |
mouse |
Michal Hrdlicka, Iva Dudova, Irena Beranova, Jiri Lisy, Tomas Belsan, Jiri Neuwirth, Vladimir Komarek, Ludvika Faladova, Marketa Havlovicova, Zdenek Sedlacek, Marek Blatny, Tomas Urbane. Subtypes of autism by cluster analysis based on structural MRI data. European child & adolescent psychiatry. vol 14. issue 3. 2005-10-21. PMID:15959659. |
cluster 2: showed the largest sizes of the amygdala and hippocampus (hpc), the least abnormal visual response on the cars, the lowest frequency of epilepsy and the least frequent abnormal psychomotor development during the first year of life. |
2005-10-21 |
2023-08-12 |
Not clear |
Sébastien J Thuault, Jon T Brown, Andrew R Calver, Graham L Collingridge, Andrew Randall, Ceri H Davie. Mechanisms contributing to the exacerbated epileptiform activity in hippocampal slices expressing a C-terminal truncated GABA(B2) receptor subunit. Epilepsy research. vol 65. issue 1-2. 2005-10-19. PMID:15979855. |
these data suggest that the loss of gaba(b) receptor function in deltagb2-ct hippocampal slices promotes depolarising gaba(a) receptor-mediated events, which in turn, leads to the generation of ictal-like events, which may contribute to the epilepsy phenotype observed in vivo. |
2005-10-19 |
2023-08-12 |
mouse |
Ryuta Koyama, Yuji Ikegay. To BDNF or not to BDNF: that is the epileptic hippocampus. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 11. issue 4. 2005-10-19. PMID:16061515. |
in epileptogenesis-related brain areas, including the hippocampus, bdnf is up-regulated in the course of the development of epilepsy and induces a collapse of balanced excitation and inhibition, eventually exerting its epileptogenic effects. |
2005-10-19 |
2023-08-12 |
Not clear |
Alan W L Chiu, Sarit Daniel, Houman Khosravani, Peter L Carlen, Berj L Bardakjia. Prediction of seizure onset in an in-vitro hippocampal slice model of epilepsy using Gaussian-based and wavelet-based artificial neural networks. Annals of biomedical engineering. vol 33. issue 6. 2005-10-06. PMID:16078619. |
prediction of seizure onset in an in-vitro hippocampal slice model of epilepsy using gaussian-based and wavelet-based artificial neural networks. |
2005-10-06 |
2023-08-12 |
rat |
T Salmenperä, M Könönen, N Roberts, R Vanninen, A Pitkänen, R Kälviäine. Hippocampal damage in newly diagnosed focal epilepsy: a prospective MRI study. Neurology. vol 64. issue 1. 2005-09-27. PMID:15642905. |
hippocampal damage in newly diagnosed focal epilepsy: a prospective mri study. |
2005-09-27 |
2023-08-12 |
Not clear |
T Salmenperä, M Könönen, N Roberts, R Vanninen, A Pitkänen, R Kälviäine. Hippocampal damage in newly diagnosed focal epilepsy: a prospective MRI study. Neurology. vol 64. issue 1. 2005-09-27. PMID:15642905. |
to examine the longitudinal appearance of hippocampal (hc) damage in a prospective follow-up study of patients with newly diagnosed epilepsy. |
2005-09-27 |
2023-08-12 |
Not clear |
Rajiv Mohanraj, Martin J Brodi. Outcomes in newly diagnosed localization-related epilepsies. Seizure. vol 14. issue 5. 2005-09-23. PMID:15876543. |
remission rates in patients with cortical dysplasias (60%), hippocampal atrophy (50%) and primary brain tumors (52%) appeared no different from those with other symptomatic epilepsies. |
2005-09-23 |
2023-08-12 |
Not clear |
Rajiv Mohanraj, Martin J Brodi. Outcomes in newly diagnosed localization-related epilepsies. Seizure. vol 14. issue 5. 2005-09-23. PMID:15876543. |
overall, 20-40% patients with each epilepsy syndrome reported no further seizures after starting aed treatment including 21% with hippocampal atrophy and 33% with cortical dysplasia. |
2005-09-23 |
2023-08-12 |
Not clear |
Suhita Nadkarni, Peter Jun. Synaptic inhibition and pathologic hyperexcitability through enhanced neuron-astrocyte interaction: a modeling study. Journal of integrative neuroscience. vol 4. issue 2. 2005-09-23. PMID:15988798. |
recently, upregulation of metabotropic glutamate receptors (mglurs) on hippocampal astrocytes in epileptic tissues has become part of the etiology of epilepsy and suggests the involvement of astrocytes in the disease. |
2005-09-23 |
2023-08-12 |
Not clear |
Simone Denise Salamoni, Jaderson Costa da Costa, Mário Sérgio Palma, Katsuhiro Konno, Ken-Ichi Nihei, Andréa Alencar Tavares, Daniela Souza de Abreu, Gianina Teribele Venturin, Fernanda de Borba Cunha, Raquel Mattos de Oliveira, Ricardo Vaz Bred. Antiepileptic effect of acylpolyaminetoxin JSTX-3 on rat hippocampal CA1 neurons in vitro. Brain research. vol 1048. issue 1-2. 2005-09-14. PMID:15913572. |
epilepsy has been studied in vitro, mostly on rat hippocampus, through brain slices techniques. |
2005-09-14 |
2023-08-12 |
rat |
Maria Thom, Jiemin Zhou, Lillian Martinian, Sanjay Sisodiy. Quantitative post-mortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. Brain : a journal of neurology. vol 128. issue Pt 6. 2005-09-13. PMID:15758032. |
quantitative post-mortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. |
2005-09-13 |
2023-08-12 |
human |
Maria Thom, Jiemin Zhou, Lillian Martinian, Sanjay Sisodiy. Quantitative post-mortem study of the hippocampus in chronic epilepsy: seizures do not inevitably cause neuronal loss. Brain : a journal of neurology. vol 128. issue Pt 6. 2005-09-13. PMID:15758032. |
hippocampal sclerosis describes a pattern of neuronal loss and gliosis involving the medial temporal structures most often encountered in patients with epilepsy. |
2005-09-13 |
2023-08-12 |
human |
Atticus H Hainsworth, Daniela Bermpohl, Tania E Webb, Ribal Darwish, Gary Fiskum, Jianhua Qiu, Deirdre McCarthy, Michael A Moskowitz, Michael J Whale. Expression of cellular FLICE inhibitory proteins (cFLIP) in normal and traumatic murine and human cerebral cortex. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 25. issue 8. 2005-08-24. PMID:15815586. |
cflip-delta was increased in a subset of reactive astrocytes in pericontusional cortex and hippocampus at 48 to 72 h. low levels of both cflip isoforms were detected in human cortical tissue with no tbi, from four patients undergoing brain surgery for epilepsy and <24 h post mortem from three patients without cns pathologic assessment. |
2005-08-24 |
2023-08-12 |
mouse |
Zhi-guo Wu, Bo Xiao, Xiao-su Yang, Fa-qing Tang, Yi Zeng, Guang-jie Xi. [The gene expression patterns of genetic P77PMC epilepsy-prone rats' hippocampus]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 21. issue 6. 2005-08-17. PMID:15583996. |
to find out the differentially expressed genes in the hippocampus of the rats with genetic epilepsy so as to lay a foundation for exploring the pathogenesis of epilepsy by means of cdna array technology. |
2005-08-17 |
2023-08-12 |
rat |
Patric Meyer, Axel Mecklinger, Thomas Grunwald, Juergen Fell, Christian E Elger, Angela D Friederic. Language processing within the human medial temporal lobe. Hippocampus. vol 15. issue 4. 2005-08-11. PMID:15714509. |
we recorded event-related potentials (erps) directly from two substructures of the medial temporal lobe (mtl), the rhinal cortex and the hippocampus proper, while epilepsy patients listened to sentences that either were correct or contained semantic or syntactic violations. |
2005-08-11 |
2023-08-12 |
human |
João Pereira Leite, Luciano Neder, Gabriel Maisonnave Arisi, Carlos Gilberto Carlotti, João Alberto Assirati, Jorge Eduardo Moreir. Plasticity, synaptic strength, and epilepsy: what can we learn from ultrastructural data? Epilepsia. vol 46 Suppl 5. 2005-07-28. PMID:15987268. |
in this review, we focus on experimental studies that have analyzed at the ultrastructural level the consequences of ltp in rodents, and plastic changes in the hippocampus of experimental models of epilepsy and human tissue obtained during surgeries for intractable temporal lobe epilepsy (tle). |
2005-07-28 |
2023-08-12 |
human |
E P Krugliakova, A V Khovriakov, N P Shikhanov, G M McKhann II, I Vael, P P Krugliakov, A A Sosuno. [Nestin-expressing cells in the human hippocampus]. Morfologiia (Saint Petersburg, Russia). vol 126. issue 6. 2005-07-07. PMID:15839245. |
in this work nestin expression was studied in the hippocampus obtained from patients with epilepsy. |
2005-07-07 |
2023-08-12 |
human |