| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arabinda Das, Misty McDowell, Casey M O'Dell, Megan E Busch, Joshua A Smith, Swapan K Ray, Naren L Bani. Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons. Neurochemical research. vol 35. issue 12. 2011-04-28. PMID:21127971. |
injection of rats with kainic acid (ka), a non-n-methyl-d-aspartate (nmda) type glutamate receptor agonist, induces recurrent (delayed) convulsive seizures and subsequently hippocampal neurodegeneration, which is reminiscent of human epilepsy. |
2011-04-28 |
2023-08-12 |
human |
| D A Gill, J F Bastlund, W P Watson, C L Ryan, D S Reynolds, R A Taske. Neonatal exposure to low-dose domoic acid lowers seizure threshold in adult rats. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600646. |
exposing sprague-dawley rat pups to very low, sub-convulsant doses of domoic acid (dom) during perinatal development has been previously shown to result in seizure-like activity in adulthood similar to partial complex epilepsy in humans, and to produce cellular and molecular changes in the dentate gyrus and area ca-3 of the hippocampus. |
2011-04-18 |
2023-08-12 |
rat |
| Jobin Mathew, Gireesh Gangadharan, Korah P Kuruvilla, C S Paulos. Behavioral deficit and decreased GABA receptor functional regulation in the hippocampus of epileptic rats: effect of Bacopa monnieri. Neurochemical research. vol 36. issue 1. 2011-04-18. PMID:20821261. |
our results suggest that decreased gaba receptors in the hippocampus have an important role in epilepsy associated behavioral deficit, bacopa monnieri and bacoside-a have clinical significance in the management of epilepsy. |
2011-04-18 |
2023-08-12 |
rat |
| Shang-Der Chen, Alice Y W Chang, Yao-Chung Chuan. The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis. Journal of bioenergetics and biomembranes. vol 42. issue 6. 2011-04-14. PMID:21153870. |
therefore, protection of mitochondria from bioenergetic failure and oxidative stress in the hippocampus may open a new vista to the development of effective neuroprotective strategies against seizure-induced brain damage and to the design of novel treatment perspectives against therapy-resistant forms of epilepsy. |
2011-04-14 |
2023-08-12 |
Not clear |
| Olaf E M G Schijns, Christian G Bien, Michael Majores, Marec von Lehe, Horst Urbach, Albert Becker, Johannes Schramm, Christian E Elger, Hans Clusman. Presence of temporal gray-white matter abnormalities does not influence epilepsy surgery outcome in temporal lobe epilepsy with hippocampal sclerosis. Neurosurgery. vol 68. issue 1. 2011-04-13. PMID:21150756. |
presence of temporal gray-white matter abnormalities does not influence epilepsy surgery outcome in temporal lobe epilepsy with hippocampal sclerosis. |
2011-04-13 |
2023-08-12 |
Not clear |
| John J McAuliffe, Stefanie L Bronson, Michael S Hester, Brian L Murphy, Renée Dahlquist-Topalá, David A Richards, Steve C Danze. Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy. Hippocampus. vol 21. issue 1. 2011-04-04. PMID:20014385. |
impaired gating by hippocampal dentate granule cells may promote the development of limbic epilepsy by facilitating seizure spread through the hippocampal trisynaptic circuit. |
2011-04-04 |
2023-08-12 |
mouse |
| Tarik Akman, Haydar Erken, Goksemin Acar, Elif Bolat, Zahir Kizilay, Feridun Acar, Osman Gen. Effects of the hippocampal deep brain stimulation on cortical epileptic discharges in penicillin - induced epilepsy model in rats. Turkish neurosurgery. vol 21. issue 1. 2011-04-04. PMID:21294084. |
effects of the hippocampal deep brain stimulation on cortical epileptic discharges in penicillin - induced epilepsy model in rats. |
2011-04-04 |
2023-08-12 |
rat |
| Tarik Akman, Haydar Erken, Goksemin Acar, Elif Bolat, Zahir Kizilay, Feridun Acar, Osman Gen. Effects of the hippocampal deep brain stimulation on cortical epileptic discharges in penicillin - induced epilepsy model in rats. Turkish neurosurgery. vol 21. issue 1. 2011-04-04. PMID:21294084. |
the aim was to evaluate the effects of high frequency hippocampal stimulation on cortical epileptic activity in penicillin-induced epilepsy model. |
2011-04-04 |
2023-08-12 |
rat |
| Tim Wehner, Deepak K Lachhwani, William Bingaman, Senay Haspolat, Ajay Gupta, Prakash Kotagal, Ingrid Tuxhorn, Elaine Wylli. Epilepsy surgery outcome in coexisting symptomatic refractory focal epilepsy and benign focal epilepsy of childhood. Pediatric neurology. vol 44. issue 1. 2011-04-01. PMID:21147388. |
two patients had left temporal epilepsy due to a malformation of cortical development; one of these had dual pathology, with additional ipsilateral hippocampal sclerosis. |
2011-04-01 |
2023-08-12 |
Not clear |
| J Dyhrfjeld-Johnsen, Y Berdichevsky, W Swiercz, H Sabolek, K J Stale. Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. vol 27. issue 6. 2011-03-28. PMID:21076333. |
in organotypic hippocampal slice cultures, principal neurons form aberrant excitatory connections with other principal cells in response to slicing induced deafferentation, similar to mechanisms underlying epileptogenesis in posttraumatic epilepsy. |
2011-03-28 |
2023-08-12 |
Not clear |
| E López H, M Fohlen, A Lelouch-Tubiana, O Robain, C Jalin, C Bulteau, G Dorfmüller, O Dulac, O Delaland. Heterotopia associated with hippocampal sclerosis: an under-recognized cause of early onset epilepsy in children operated on for temporal lobe epilepsy. Neuropediatrics. vol 41. issue 4. 2011-03-16. PMID:21086221. |
heterotopia associated with hippocampal sclerosis: an under-recognized cause of early onset epilepsy in children operated on for temporal lobe epilepsy. |
2011-03-16 |
2023-08-12 |
Not clear |
| Brandon Korman, Byron Bernal, Michael Duchowny, Prasanna Jayakar, Nolan Altman, Genoveva Garaycoa, Trevor Resnick, Gustavo Re. Atypical propositional language organization in prenatal and early-acquired temporal lobe lesions. Journal of child neurology. vol 25. issue 8. 2011-02-22. PMID:20139401. |
we evaluated 30 right-handed subjects with intractable epilepsy due to either focal cortical dysplasia or hippocampal sclerosis with neuropsychological testing and functional mri prior to epilepsy surgery. |
2011-02-22 |
2023-08-12 |
human |
| Klaus Fliessbach, Juri-Alexander Witt, Jenny Packheiser, Marec von Lehe, Christian E Elger, Christoph Helmstaedte. Depth-of-processing effects on memory encoding after selective amygdalohippocampectomy. Behavioural brain research. vol 216. issue 1. 2011-02-18. PMID:20797413. |
therefore, we tested, whether chronic left hippocampal damage in epilepsy patients after selective amygdalohippocampectomy (sah) diminishes the depth-of-processing effect in an incidental learning task. |
2011-02-18 |
2023-08-12 |
human |
| Francine Blanc, Lillian Martinian, Ioannis Liagkouras, Claudia Catarino, Sanjay M Sisodiya, Maria Tho. Investigation of widespread neocortical pathology associated with hippocampal sclerosis in epilepsy: a postmortem study. Epilepsia. vol 52. issue 1. 2011-02-14. PMID:21198557. |
investigation of widespread neocortical pathology associated with hippocampal sclerosis in epilepsy: a postmortem study. |
2011-02-14 |
2023-08-12 |
Not clear |
| Francine Blanc, Lillian Martinian, Ioannis Liagkouras, Claudia Catarino, Sanjay M Sisodiya, Maria Tho. Investigation of widespread neocortical pathology associated with hippocampal sclerosis in epilepsy: a postmortem study. Epilepsia. vol 52. issue 1. 2011-02-14. PMID:21198557. |
one possible cause for surgical failure following temporal lobectomy for the treatment of epilepsy due to classical hippocampal sclerosis (chs) is the presence of more widespread cortical changes. |
2011-02-14 |
2023-08-12 |
Not clear |
| Brian Neville, Diane Gindne. Febrile seizures are a syndrome of secondarily generalized hippocampal epilepsy. Developmental medicine and child neurology. vol 52. issue 12. 2011-01-31. PMID:20722664. |
febrile seizures are a syndrome of secondarily generalized hippocampal epilepsy. |
2011-01-31 |
2023-08-12 |
Not clear |
| Jeffrey Noebel. A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia. vol 52 Suppl 1. 2011-01-31. PMID:21214538. |
the confluence of hyperexcitability and excitotoxicity, combined with the challenge of seizure detection in the human hippocampus, make epilepsy in these individuals extremely important to correctly diagnose and treat. |
2011-01-31 |
2023-08-12 |
mouse |
| Luciana D'Alessio, Hector Konopka, Ester María López, Eduardo Seoane, Damián Consalvo, Silvia Oddo, Silvia Kochen, Juan José López-Cost. Doublecortin (DCX) immunoreactivity in hippocampus of chronic refractory temporal lobe epilepsy patients with hippocampal sclerosis. Seizure. vol 19. issue 9. 2011-01-28. PMID:20888264. |
however chronic experimental models of epilepsy and studies performed in human epilepsy showed controversial results suggesting a reduction in hippocampal neurogenesis in late stages of the disease. |
2011-01-28 |
2023-08-12 |
human |
| Ji-Eun Kim, Seong-Il Yeo, Hea Jin Ryu, Min-Ju Kim, Duk-Soo Kim, Seung-Mook Jo, Tae-Cheon Kan. Astroglial loss and edema formation in the rat piriform cortex and hippocampus following pilocarpine-induced status epilepticus. The Journal of comparative neurology. vol 518. issue 22. 2011-01-21. PMID:20886625. |
in the present study we analyzed aquaporin-4 (aqp4) immunoreactivity in the piriform cortex (pc) and the hippocampus of pilocarpine-induced rat epilepsy model to elucidate the roles of aqp4 in brain edema following status epilepticus (se). |
2011-01-21 |
2023-08-12 |
rat |
| Nisha Nagarkatti, Laxmikant S Deshpande, Dawn S Carter, Robert J DeLorenz. Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20597971. |
in the sprague-dawley rat pilocarpine model of status epilepticus-induced acquired epilepsy, intracellular calcium has been shown to increase in hippocampal neurons during status epilepticus and remain elevated well past the duration of the injury in those animals that develop epilepsy. |
2011-01-13 |
2023-08-12 |
rat |