| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nanchang Xie, Cui Wang, Yajun Lian, Chuanjie Wu, Haifeng Zhang, Qian Zhan. Puerarin protects hippocampal neurons against cell death in pilocarpine-induced seizures through antioxidant and anti-apoptotic mechanisms. Cellular and molecular neurobiology. vol 34. issue 8. 2015-06-10. PMID:25151533. |
in this study, we found that pretreatment with puerarin significantly attenuated the neuronal death in the hippocampus of rats with pilocarpine-induced epilepsy. |
2015-06-10 |
2023-08-13 |
rat |
| Patrício Soares-da-Silva, Nuno Pires, Maria João Bonifácio, Ana I Loureiro, Nuno Palma, Lyndon C Wrigh. Eslicarbazepine acetate for the treatment of focal epilepsy: an update on its proposed mechanisms of action. Pharmacology research & perspectives. vol 3. issue 2. 2015-06-03. PMID:26038700. |
data reviewed here suggest that esl and eslicarbazepine demonstrated the following in animal models: (1) the selectivity of interaction with the inactive state of the voltage-gated sodium channel (vgsc), (2) reduction in vgsc availability through enhancement of slow inactivation, instead of alteration of fast inactivation of vgsc, (3) the failure to cause a paradoxical upregulation of persistent na(+) current (i nap), and (4) the reduction in firing frequencies of excitatory neurons in dissociated hippocampal cells from patients with epilepsy who were pharmacoresistant to carbamazepine (cbz). |
2015-06-03 |
2023-08-13 |
Not clear |
| B Van Nieuwenhuyse, R Raedt, J Delbeke, W J Wadman, P Boon, K Vonc. In search of optimal DBS paradigms to treat epilepsy: bilateral versus unilateral hippocampal stimulation in a rat model for temporal lobe epilepsy. Brain stimulation. vol 8. issue 2. 2015-05-22. PMID:25554585. |
in search of optimal dbs paradigms to treat epilepsy: bilateral versus unilateral hippocampal stimulation in a rat model for temporal lobe epilepsy. |
2015-05-22 |
2023-08-13 |
rat |
| B Van Nieuwenhuyse, R Raedt, J Delbeke, W J Wadman, P Boon, K Vonc. In search of optimal DBS paradigms to treat epilepsy: bilateral versus unilateral hippocampal stimulation in a rat model for temporal lobe epilepsy. Brain stimulation. vol 8. issue 2. 2015-05-22. PMID:25554585. |
these patients are unsuitable candidates for epilepsy surgery but may be amenable to hippocampal deep brain stimulation (dbs). |
2015-05-22 |
2023-08-13 |
rat |
| Weiwen Wang, Xiaoyang Liao, Zhenghui Yang, Hang Lin, Qingsong Wang, Yuxian Wu, Yu Li. [Research on expression and function of phosphorylated DARPP-32 on pentylenetetrazol-induced epilepsy model of rat]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 31. issue 3. 2015-05-19. PMID:25219249. |
the present study is to explore the change process and distribution of phosphorylated darpp-32 (p-darpp-32) in rat brain including cortex, hippocampus and striatum and to further deduce whether p-darpp-32 was possibly involved in epilepsy induced by repetitive low doses of pentylenetetrazol (ptz). |
2015-05-19 |
2023-08-13 |
rat |
| Weiwen Wang, Xiaoyang Liao, Zhenghui Yang, Hang Lin, Qingsong Wang, Yuxian Wu, Yu Li. [Research on expression and function of phosphorylated DARPP-32 on pentylenetetrazol-induced epilepsy model of rat]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 31. issue 3. 2015-05-19. PMID:25219249. |
the temporal time change and distribution of p-darpp-32 suggest that phosphorylation of darpp-32 may be involved in ptz-induced epilepsy in rat brain including cortex, hippocampus and striatum, and p-darpp-32 may play a central role in the onset of se. |
2015-05-19 |
2023-08-13 |
rat |
| S J Yin, D Han, L L. [The characteristic unit discharges related to epilepsy recorded synchronously from dual hippocampi induced by tetanization of the right dorsal hippocampus in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 3. 2015-05-14. PMID:21189629. |
[the characteristic unit discharges related to epilepsy recorded synchronously from dual hippocampi induced by tetanization of the right dorsal hippocampus in rats]. |
2015-05-14 |
2023-08-12 |
rat |
| S J Yin, D Han, L L. [The characteristic unit discharges related to epilepsy recorded synchronously from dual hippocampi induced by tetanization of the right dorsal hippocampus in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 3. 2015-05-14. PMID:21189629. |
to study the characteristics of unit discharges related to epilepsy of hippocampal neuron in both hemispheres in intact rats. |
2015-05-14 |
2023-08-12 |
rat |
| Fabio Moroni, Lino Nobili, Giuseppe Iaria, Ivana Sartori, Cristina Marzano, Daniela Tempesta, Paola Proserpio, Giorgio Lo Russo, Francesca Gozzo, Carlo Cipolli, Luigi De Gennaro, Michele Ferrar. Hippocampal slow EEG frequencies during NREM sleep are involved in spatial memory consolidation in humans. Hippocampus. vol 24. issue 10. 2015-05-12. PMID:24796545. |
aimed to evaluate the effects of spatial learning on human hippocampal sleep eeg activity, we recorded hippocampal stereo-eeg (seeg) in a group of refractory epilepsy patients undergoing presurgical clinical evaluation, after a training on a spatial navigation task. |
2015-05-12 |
2023-08-13 |
human |
| Christopher D Makinson, Brian S Tanaka, Tyra Lamar, Alan L Goldin, Andrew Escay. Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance. Neurobiology of disease. vol 68. 2015-05-11. PMID:24704313. |
our results identify the hippocampus as an important structure in the mediation of scn8a-dependent seizure protection and suggest that selective targeting of scn8a activity might be efficacious in patients with epilepsy. |
2015-05-11 |
2023-08-13 |
mouse |
| Satsuki Watanabe, Dongmei An, Mona Safi-Harb, François Dubeau, Jean Gotma. Hemodynamic response function (HRF) in epilepsy patients with hippocampal sclerosis and focal cortical dysplasia. Brain topography. vol 27. issue 5. 2015-05-11. PMID:24718726. |
hemodynamic response function (hrf) in epilepsy patients with hippocampal sclerosis and focal cortical dysplasia. |
2015-05-11 |
2023-08-13 |
Not clear |
| Zhiyi Luo, Yu Fang, Lu Zhan. The effects of antiepileptic drug valproic acid on apoptosis of hippocampal neurons in epileptic rats. Pakistan journal of pharmaceutical sciences. vol 28. issue 1 Suppl. 2015-04-30. PMID:25631498. |
based on the experiment, we reached the conclusion that, vpa showed no harm to epileptic rats and the hippocampal neuronal apoptosis after epilepsy and anti-epileptic drug was probably resulted from the decrease of bcl-2 expression and increase of bax expression. |
2015-04-30 |
2023-08-13 |
rat |
| Meng Na, Yanshu Liu, Chen Shi, Wenpeng Gao, Haitao Ge, Yu Wang, Haiyang Wang, Yu Long, Hong Shen, Changbin Shi, Zhiguo Li. Prognostic value of CA4/DG volumetry with 3T magnetic resonance imaging on postoperative outcome of epilepsy patients with dentate gyrus pathology. Epilepsy research. vol 108. issue 8. 2015-04-20. PMID:25085233. |
hippocampal sclerosis (hs), the most common feature of mesial temporal lobe epilepsy (mtle), is widely accepted as surgical indication for refractory epilepsy. |
2015-04-20 |
2023-08-13 |
Not clear |
| Fazheng Shen, Lei Hui, Xiang Zhou, Zhongwei Wang, Xinli Zhao, Wenke Zhou, Xinzhong Zhang, Guangming Yang, Feng Wang, Tao Su. [Effects of hippocampal stimulus on α₅ subunit of extrasynaptic GABA(A) receptor in kainic acid-induced epileptic rats]. Zhonghua yi xue za zhi. vol 94. issue 23. 2015-04-08. PMID:25154851. |
to observe the effects of electrical hippocampal stimulation of α₅ subunit of extrasynaptic gaba(a) receptor in kainic acid-induced epileptic rats, explore the optimal therapeutic parameters and elucidate the possible mechanism of electrical stimulation for hippocampal epilepsy. |
2015-04-08 |
2023-08-13 |
rat |
| Jianxin Liu, Yong Liu, Fengru Tan. [Survival of calbindin, calretinin and parvalbumin positive neurons in mouse hippocampal CA area at chronic stage of pilocarpine-induced epilepsy]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 38. issue 5. 2015-03-30. PMID:23719530. |
[survival of calbindin, calretinin and parvalbumin positive neurons in mouse hippocampal ca area at chronic stage of pilocarpine-induced epilepsy]. |
2015-03-30 |
2023-08-12 |
mouse |
| Jianxin Liu, Yong Liu, Fengru Tan. [Survival of calbindin, calretinin and parvalbumin positive neurons in mouse hippocampal CA area at chronic stage of pilocarpine-induced epilepsy]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 38. issue 5. 2015-03-30. PMID:23719530. |
to analyze the survival and the changes of proportions of calbindin, calretinin and parvalbumin positive neurons in mouse hippocampal ca area at chronic stage of pilocarpine-induced epilepsy. |
2015-03-30 |
2023-08-12 |
mouse |
| Huicong Kang, Qi Hu, Xiaoyan Liu, Yinhe Liu, Feng Xu, Xiang Li, Suiqiang Zh. Reconstruction of the adenosine system by bone marrow-derived mesenchymal stem cell transplantation. Neural regeneration research. vol 7. issue 4. 2015-03-25. PMID:25806064. |
in the present study, we transplanted bone marrow-derived mesenchymal stem cells into the ca3 area of the hippocampus of chronic epilepsy rats kindled by lithium chloride-pilocarpine. |
2015-03-25 |
2023-08-13 |
rat |
| Stjepana Kovac, Beate Diehl, Tim Wehner, Chiara Fois, Nathan Toms, Matthew C Walker, John S Dunca. Gelastic seizures: incidence, clinical and EEG features in adult patients undergoing video-EEG telemetry. Epilepsia. vol 56. issue 1. 2015-03-18. PMID:25516460. |
outcome of epilepsy surgery was related to the underlying pathology; two patients with hippocampal sclerosis had good outcomes following temporal lobe resection and one of four patients with hypothalamic hamartomas undergoing gamma knife surgery had a good outcome. |
2015-03-18 |
2023-08-13 |
Not clear |
| Yi Liang, Hongbin Sun, Liang Yu, Baoming He, Yan Xi. Scorpion ethanol extract and valproic acid effects on hippocampal glial fibrillary acidic protein expression in a rat model of chronic-kindling epilepsy induced by lithium chloride-pilocarpine. Neural regeneration research. vol 7. issue 6. 2015-03-16. PMID:25774184. |
scorpion ethanol extract and valproic acid effects on hippocampal glial fibrillary acidic protein expression in a rat model of chronic-kindling epilepsy induced by lithium chloride-pilocarpine. |
2015-03-16 |
2023-08-13 |
rat |
| Yi Liang, Hongbin Sun, Liang Yu, Baoming He, Yan Xi. Scorpion ethanol extract and valproic acid effects on hippocampal glial fibrillary acidic protein expression in a rat model of chronic-kindling epilepsy induced by lithium chloride-pilocarpine. Neural regeneration research. vol 7. issue 6. 2015-03-16. PMID:25774184. |
the present study analyzed the effects of ethanol extracts of scorpion on epilepsy prevention and hippocampal expression of glial fibrillary acidic protein in a lithium chloride-pilocarpine epileptic rat model. |
2015-03-16 |
2023-08-13 |
rat |