| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paolo Roncon, Marie Soukupovà, Anna Binaschi, Chiara Falcicchia, Silvia Zucchini, Manuela Ferracin, Sarah R Langley, Enrico Petretto, Michael R Johnson, Gianluca Marucci, Roberto Michelucci, Guido Rubboli, Michele Simonat. MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy--comparison with human epileptic samples. Scientific reports. vol 5. 2016-08-19. PMID:26382856. |
in this study, mirna microarrays were performed on laser-microdissected hippocampal granule cell layer (gcl) and on plasma, at different time points in the development of pilocarpine-induced epilepsy in the rat: latency, first spontaneous seizure and chronic epileptic phase. |
2016-08-19 |
2023-08-13 |
human |
| J Tchekalarova, M Shishmanova, D Atanasova, M Stefanova, L Alova, N Lazarov, K Georgiev. Effect of endurance training on seizure susceptibility, behavioral changes and neuronal damage after kainate-induced status epilepticus in spontaneously hypertensive rats. Brain research. vol 1625. 2016-08-15. PMID:26319691. |
our results indicate that prior exercise is an effective means to attenuate ka-induced seizures and comorbid behavioral changes in a model of hypertension and epilepsy suggesting a potential influence of hippocampal 5-ht on a comorbid depression. |
2016-08-15 |
2023-08-13 |
rat |
| A Sierra, O Gröhn, A Pitkäne. Imaging microstructural damage and plasticity in the hippocampus during epileptogenesis. Neuroscience. vol 309. 2016-08-09. PMID:25934032. |
the hippocampus is the seizure-initiating zone in many epilepsy patients as well as in animal models of epilepsy. |
2016-08-09 |
2023-08-13 |
Not clear |
| Juri-Alexander Witt, Roland Coras, Johannes Schramm, Albert J Becker, Christian E Elger, Ingmar Blümcke, Christoph Helmstaedte. Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy. Journal of neurology. vol 262. issue 10. 2016-08-09. PMID:26138541. |
in 104 patients who had undergone epilepsy surgery for unilateral mtle, we analyzed pre- to postoperative changes of verbal and figural memory as a function of segmental neuronal cell densities of the resected hippocampus (cornu ammonis, ca1-4; internal and external limb of the dentate gyrus, dg). |
2016-08-09 |
2023-08-13 |
Not clear |
| Juri-Alexander Witt, Roland Coras, Johannes Schramm, Albert J Becker, Christian E Elger, Ingmar Blümcke, Christoph Helmstaedte. Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy. Journal of neurology. vol 262. issue 10. 2016-08-09. PMID:26138541. |
presurgical verbal memory performance may be taken as a marker of ipsilateral left hippocampal integrity and may contribute to individual risk-benefit evaluations before epilepsy surgery. |
2016-08-09 |
2023-08-13 |
Not clear |
| R Coras, I Blümck. Clinico-pathological subtypes of hippocampal sclerosis in temporal lobe epilepsy and their differential impact on memory impairment. Neuroscience. vol 309. 2016-08-09. PMID:26254830. |
different patterns of hippocampal cell loss have been identified in tle patients and are recently classified by the international league against epilepsy (ilae) into four distinct subtypes in order to stratify the heterogenous group of tle patients also with respect to postsurgical outcome. |
2016-08-09 |
2023-08-13 |
human |
| Yi Lu, Cheng Zhong, Lulu Wang, Pengfei Wei, Wei He, Kang Huang, Yi Zhang, Yang Zhan, Guoping Feng, Liping Wan. Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nature communications. vol 7. 2016-08-08. PMID:26997093. |
temporal lobe epilepsy (tle) is one of the most common drug-resistant forms of epilepsy in adults and usually originates in the hippocampal formations. |
2016-08-08 |
2023-08-13 |
mouse |
| Idil Cavus, Gabriel A Widi, Robert B Duckrow, Hitten Zaveri, Jeremy T Kennard, John Krystal, Dennis D Spence. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. vol 57. issue 2. 2016-08-01. PMID:26749134. |
50 hz hippocampal stimulation in refractory epilepsy: higher level of basal glutamate predicts greater release of glutamate. |
2016-08-01 |
2023-08-13 |
Not clear |
| Idil Cavus, Gabriel A Widi, Robert B Duckrow, Hitten Zaveri, Jeremy T Kennard, John Krystal, Dennis D Spence. 50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate. Epilepsia. vol 57. issue 2. 2016-08-01. PMID:26749134. |
we examined the effect of 50 hz stimulation on glutamate release and its relationship to interictal levels in the hippocampus of patients with epilepsy. |
2016-08-01 |
2023-08-13 |
Not clear |
| Licheng Chen, Hao Zheng, Shimeng Zhan. Involvement of upregulation of miR-210 in a rat epilepsy model. Neuropsychiatric disease and treatment. vol 12. 2016-07-29. PMID:27471387. |
our data showed that morphological changes of hippocampal neurons and apoptosis triggered by epilepsy were mitigated by mir-210 inhibition. |
2016-07-29 |
2023-08-13 |
rat |
| Ingmar Blümcke, Eleonora Aronica, Hajime Miyata, Harvey B Sarnat, Maria Thom, Karl Roessler, Bertil Rydenhag, Lara Jehi, Pavel Krsek, Samuel Wiebe, Roberto Spreafic. International recommendation for a comprehensive neuropathologic workup of epilepsy surgery brain tissue: A consensus Task Force report from the ILAE Commission on Diagnostic Methods. Epilepsia. vol 57. issue 3. 2016-07-28. PMID:26839983. |
however, application of international consensus classification systems to common epileptic pathologies (e.g., focal cortical dysplasia [fcd] and hippocampal sclerosis [hs]) necessitates standardized protocols for neuropathologic workup of epilepsy surgery specimens. |
2016-07-28 |
2023-08-13 |
Not clear |
| Lucian Medrihan, Enrico Ferrea, Barbara Greco, Pietro Baldelli, Fabio Benfenat. Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 10. 2016-07-20. PMID:24962993. |
we show that deletion of synapsin ii (syn ii), a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous gaba release. |
2016-07-20 |
2023-08-13 |
mouse |
| Richard A Prayson, Jordan M Gale. Coexistent ganglioglioma, focal cortical dysplasia, and hippocampal sclerosis (triple pathology) in chronic epilepsy. Annals of diagnostic pathology. vol 19. issue 5. 2016-07-14. PMID:26235882. |
coexistent ganglioglioma, focal cortical dysplasia, and hippocampal sclerosis (triple pathology) in chronic epilepsy. |
2016-07-14 |
2023-08-13 |
Not clear |
| Richard A Prayson, Jordan M Gale. Coexistent ganglioglioma, focal cortical dysplasia, and hippocampal sclerosis (triple pathology) in chronic epilepsy. Annals of diagnostic pathology. vol 19. issue 5. 2016-07-14. PMID:26235882. |
the most commonly identified pathologies in patients with medically intractable epilepsy include focal cortical dysplasia, hippocampal sclerosis, tumors, and remote ischemic damage. |
2016-07-14 |
2023-08-13 |
Not clear |
| Y-J Kim, T-C Kan. The role of TRPC6 in seizure susceptibility and seizure-related neuronal damage in the rat dentate gyrus. Neuroscience. vol 307. 2016-07-06. PMID:26327362. |
although trpc6 plays an important role in neurite outgrowth and neuronal survival during development, trpc6 expression profiles available to identify distinctive hippocampal neuronal damage and hippocampal excitability in epilepsy are less defined. |
2016-07-06 |
2023-08-13 |
rat |
| Mustafa Nazıroğl. TRPV1 Channel: A Potential Drug Target for Treating Epilepsy. Current neuropharmacology. vol 13. issue 2. 2016-07-06. PMID:26411767. |
calcium ion accumulation in hippocampal neurons has long been known as a major contributor to the etiology of epilepsy. |
2016-07-06 |
2023-08-13 |
mouse |
| Mustafa Nazıroğl. TRPV1 Channel: A Potential Drug Target for Treating Epilepsy. Current neuropharmacology. vol 13. issue 2. 2016-07-06. PMID:26411767. |
trpv1 is a calcium-permeable channel and mediator of epilepsy in the hippocampus. |
2016-07-06 |
2023-08-13 |
mouse |
| Carmen Barba, Sylvain Rheims, Lorella Minotti, Marc Guénot, Dominique Hoffmann, Stephan Chabardès, Jean Isnard, Philippe Kahane, Philippe Ryvli. Temporal plus epilepsy is a major determinant of temporal lobe surgery failures. Brain : a journal of neurology. vol 139. issue Pt 2. 2016-06-30. PMID:26700686. |
in this study all patients from two epilepsy surgery programmes who fulfilled the following criteria were included: (i) operated from an anterior temporal lobectomy or disconnection between january 1990 and december 2001; (ii) magnetic resonance imaging normal or showing signs of hippocampal sclerosis; and (iii) postoperative follow-up ≥ 24 months for seizure-free patients. |
2016-06-30 |
2023-08-13 |
Not clear |
| Carmen Barba, Sylvain Rheims, Lorella Minotti, Marc Guénot, Dominique Hoffmann, Stephan Chabardès, Jean Isnard, Philippe Kahane, Philippe Ryvli. Temporal plus epilepsy is a major determinant of temporal lobe surgery failures. Brain : a journal of neurology. vol 139. issue Pt 2. 2016-06-30. PMID:26700686. |
of 168 patients included, 108 (63.7%) underwent stereoelectroencephalography, 131 (78%) had hippocampal sclerosis, 149 suffered from unilateral temporal lobe epilepsy (88.7%), one from bitemporal epilepsy (0.6%) and 18 (10.7%) from temporal plus epilepsy. |
2016-06-30 |
2023-08-13 |
Not clear |
| Carmen Barba, Sylvain Rheims, Lorella Minotti, Marc Guénot, Dominique Hoffmann, Stephan Chabardès, Jean Isnard, Philippe Kahane, Philippe Ryvli. Temporal plus epilepsy is a major determinant of temporal lobe surgery failures. Brain : a journal of neurology. vol 139. issue Pt 2. 2016-06-30. PMID:26700686. |
multivariate analyses demonstrated four predictors of seizure relapse: temporal plus epilepsy (p < 0.001), postoperative hippocampal remnant (p = 0.001), past history of traumatic or infectious brain insult (p = 0.022), and secondary generalized tonic-clonic seizures (p = 0.023). |
2016-06-30 |
2023-08-13 |
Not clear |