| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U Musshoff, U Schünke, R Köhling, E J Speckman. Alternative splicing of the NMDAR1 glutamate receptor subunit in human temporal lobe epilepsy. Brain research. Molecular brain research. vol 76. issue 2. 2000-06-05. PMID:10762714. |
specimens of hippocampus and temporal lobe cortex from patients with refractory epilepsy were obtained during neurosurgical operations and analyzed by means of the reverse transcription reaction followed by polymerase chain reaction. |
2000-06-05 |
2023-08-12 |
human |
| M Marti, G Bregola, M Morari, A Gemignani, M Simonat. Somatostatin release in the hippocampus in the kindling model of epilepsy: a microdialysis study. Journal of neurochemistry. vol 74. issue 6. 2000-06-02. PMID:10820211. |
somatostatin release in the hippocampus in the kindling model of epilepsy: a microdialysis study. |
2000-06-02 |
2023-08-12 |
rat |
| R Yang, Z N Huang, J S Chen. Anticonvulsion effect of acupuncture might be related to the decrease of neuronal and inducible nitric oxide synthases. Acupuncture & electro-therapeutics research. vol 24. issue 3-4. 2000-05-25. PMID:10768413. |
to measure the levels of hippocampal nitric oxide synthase isoforms in penicillin induced epilepsy and to test the effect of electroacupuncture (ea) on changes of these levels during epilepsy, we injected penicillin into rat hippocampus to make an epilepsy model and performed electroacupuncture treatment on "feng fu" (du 16) and "jin suo" (du 8) points in wistar rats. |
2000-05-25 |
2023-08-12 |
rat |
| C D Galvan, R A Hrachovy, K L Smith, J W Swan. Blockade of neuronal activity during hippocampal development produces a chronic focal epilepsy in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 8. 2000-05-15. PMID:10751443. |
blockade of neuronal activity during hippocampal development produces a chronic focal epilepsy in the rat. |
2000-05-15 |
2023-08-12 |
rat |
| G T Finnerty, J G Jeffery. 9-16 Hz oscillation precedes secondary generalization of seizures in the rat tetanus toxin model of epilepsy. Journal of neurophysiology. vol 83. issue 4. 2000-05-15. PMID:10758130. |
we concluded that a bilaterally synchronous 9-16 hz hippocampal oscillation played a role in the secondary generalization of focal seizures in this chronic model of limbic epilepsy. |
2000-05-15 |
2023-08-12 |
rat |
| C Dube, K Chen, M Eghbal-Ahmadi, K Brunson, I Soltesz, T Z Bara. Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long term. Annals of neurology. vol 47. issue 3. 2000-05-08. PMID:10716253. |
however, whether these neuroanatomical and electrophysiological changes promote hippocampal excitability and lead to epilepsy has remained unknown. |
2000-05-08 |
2023-08-12 |
rat |
| I Blümcke, A J Becker, C Klein, C Scheiwe, A A Lie, H Beck, A Waha, M G Friedl, R Kuhn, P Emson, C Elger, O D Wiestle. Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: correlated changes in mGluR1 mRNA and protein expression in experimental animals and human patients. Journal of neuropathology and experimental neurology. vol 59. issue 1. 2000-04-07. PMID:10744030. |
a similar pattern of increased mglur1alpha neuropil staining was found within the dg-ml of epilepsy patients (n = 42) compared with peritumoral hippocampus specimens obtained from nonepileptic patients (biopsy controls, n = 3). |
2000-04-07 |
2023-08-12 |
human |
| I Blümcke, A J Becker, C Klein, C Scheiwe, A A Lie, H Beck, A Waha, M G Friedl, R Kuhn, P Emson, C Elger, O D Wiestle. Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: correlated changes in mGluR1 mRNA and protein expression in experimental animals and human patients. Journal of neuropathology and experimental neurology. vol 59. issue 1. 2000-04-07. PMID:10744030. |
this increase corresponds to functional alterations of class i mglurs observed in seizure models and may significantly contribute to hippocampal hyperexcitability in focal human epilepsies. |
2000-04-07 |
2023-08-12 |
human |
| X Zou, X Ruan, Y Wei, C Zh. [Alterations of substance P-immune reaction positive neurons of cerebral tissues in epileptic rats]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 28. issue 2. 2000-03-28. PMID:10683920. |
employing the immunocytochemical analysis, we observed the alterations of substance p-immune reaction (sp-ir) positive neurons of the cerebral cortex, hippocampus and amygdala in rats suffering from epilepsy induced by penicillin (pen). |
2000-03-28 |
2023-08-12 |
rat |
| P Vermathen, K D Laxer, G B Matson, M W Weine. Hippocampal structures: anteroposterior N-acetylaspartate differences in patients with epilepsy and control subjects as shown with proton MR spectroscopic imaging. Radiology. vol 214. issue 2. 2000-03-02. PMID:10671587. |
hippocampal structures: anteroposterior n-acetylaspartate differences in patients with epilepsy and control subjects as shown with proton mr spectroscopic imaging. |
2000-03-02 |
2023-08-12 |
human |
| Z Ying, T L Babb, A Hilbig, E Wyllie, A Mohamed, W Bingaman, R Prayson, S Staugaitis, I Najm, H O Lüder. Hippocampal chemical anatomy in pediatric and adolescent patients with hippocampal or extrahippocampal epilepsy. Developmental neuroscience. vol 21. issue 3-5. 2000-02-10. PMID:10575247. |
hippocampal chemical anatomy in pediatric and adolescent patients with hippocampal or extrahippocampal epilepsy. |
2000-02-10 |
2023-08-12 |
Not clear |
| C E Niesen, S G. Chronic epilepsy in developing hippocampal neurons: electrophysiologic and morphologic features. Developmental neuroscience. vol 21. issue 3-5. 2000-02-10. PMID:10575256. |
chronic epilepsy in developing hippocampal neurons: electrophysiologic and morphologic features. |
2000-02-10 |
2023-08-12 |
Not clear |
| C E Niesen, S G. Chronic epilepsy in developing hippocampal neurons: electrophysiologic and morphologic features. Developmental neuroscience. vol 21. issue 3-5. 2000-02-10. PMID:10575256. |
by taking advantage of activity-dependent developmental changes in young neurons, we have developed a novel model of chronic epilepsy in cultured hippocampal slices. |
2000-02-10 |
2023-08-12 |
Not clear |
| C E Niesen, S G. Chronic epilepsy in developing hippocampal neurons: electrophysiologic and morphologic features. Developmental neuroscience. vol 21. issue 3-5. 2000-02-10. PMID:10575256. |
this model of chronic epilepsy in developing hippocampal neurons demonstrated many changes at the membrane, cellular and synaptic level that may provide new insights into the nature of epileptogenesis in the young brain. |
2000-02-10 |
2023-08-12 |
Not clear |
| Y Mori, D Kondziolka, J Balzer, W Fellows, J C Flickinger, L D Lunsford, K R Thulbor. Effects of stereotactic radiosurgery on an animal model of hippocampal epilepsy. Neurosurgery. vol 46. issue 1. 2000-02-02. PMID:10626946. |
effects of stereotactic radiosurgery on an animal model of hippocampal epilepsy. |
2000-02-02 |
2023-08-12 |
rat |
| H Straub, R Köhling, A Frieler, M Grigat, E J Speckman. Contribution of L-type calcium channels to epileptiform activity in hippocampal and neocortical slices of guinea-pigs. Neuroscience. vol 95. issue 1. 2000-01-31. PMID:10619462. |
the aim of the present investigation was to compare the antiepileptic efficacy of the specific l-type calcium channel blocker nifedipine in hippocampal and neocortical slice preparations in the mg2+-free model of epilepsy. |
2000-01-31 |
2023-08-12 |
Not clear |
| A Ekonomou, F Angelato. Upregulation of NMDA receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy. Neurochemical research. vol 24. issue 12. 2000-01-10. PMID:10591400. |
upregulation of nmda receptors in hippocampus and cortex in the pentylenetetrazol-induced "kindling" model of epilepsy. |
2000-01-10 |
2023-08-12 |
mouse |
| H Plamondon, N Blondeau, C Heurteaux, M Lazdunsk. Mutually protective actions of kainic acid epileptic preconditioning and sublethal global ischemia on hippocampal neuronal death: involvement of adenosine A1 receptors and K(ATP) channels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 19. issue 12. 2000-01-07. PMID:10598933. |
this study also investigates the effects of a mild epileptic insult on neuronal death in rat hippocampus after a subsequent, lethal epileptic stress using kainic acid (ka) as a model of epilepsy. |
2000-01-07 |
2023-08-12 |
rat |
| S Lundberg, O Eeg-Olofsson, R Raininko, K E Eeg-Olofsso. Hippocampal asymmetries and white matter abnormalities on MRI in benign childhood epilepsy with centrotemporal spikes. Epilepsia. vol 40. issue 12. 2000-01-04. PMID:10612349. |
hippocampal asymmetries and white matter abnormalities on mri in benign childhood epilepsy with centrotemporal spikes. |
2000-01-04 |
2023-08-12 |
Not clear |
| M G Naffah-Mazzacoratti, G A Argañaraz, M A Porcionatto, F A Scorza, D Amado, R Silva, M I Bellissimo, H B Nader, E A Cavalheir. Selective alterations of glycosaminoglycans synthesis and proteoglycan expression in rat cortex and hippocampus in pilocarpine-induced epilepsy. Brain research bulletin. vol 50. issue 4. 1999-12-28. PMID:10582521. |
selective alterations of glycosaminoglycans synthesis and proteoglycan expression in rat cortex and hippocampus in pilocarpine-induced epilepsy. |
1999-12-28 |
2023-08-12 |
rat |