| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Bossé, T Di Paol. Dopamine and GABAA receptor imbalance after ovariectomy in rats: model of menopause. Journal of psychiatry & neuroscience : JPN. vol 20. issue 5. 1996-01-29. PMID:8527423. |
the present results suggest that, by reducing brain dopamine receptors and increasing gabaa receptors, gonadal hormone withdrawal may predispose to schizophrenia and dyskinesia. |
1996-01-29 |
2023-08-12 |
rat |
| F Durif, M Vidailhet, A M Bonnet, J Blin, Y Agi. Levodopa-induced dyskinesias are improved by fluoxetine. Neurology. vol 45. issue 10. 1995-12-01. PMID:7477981. |
we evaluated the severity of motor disability and dyskinesias in seven levodopa-responsive patients with parkinson's disease after an acute challenge with the mixed dopamine agonist, apomorphine, before and after the administration of fluoxetine (20 mg twice per day) for 11 +/- 1 days. |
1995-12-01 |
2023-08-12 |
Not clear |
| F Durif, M Vidailhet, A M Bonnet, J Blin, Y Agi. Levodopa-induced dyskinesias are improved by fluoxetine. Neurology. vol 45. issue 10. 1995-12-01. PMID:7477981. |
the results suggest that increased brain serotoninergic transmission with fluoxetine may reduce levodopa- or dopamine agonist-induced dyskinesias without aggravating parkinsonian motor disability. |
1995-12-01 |
2023-08-12 |
Not clear |
| F Calon, M Goulet, P J Blanchet, J C Martel, M F Piercey, P J Bédard, T Di Paol. Levodopa or D2 agonist induced dyskinesia in MPTP monkeys: correlation with changes in dopamine and GABAA receptors in the striatopallidal complex. Brain research. vol 680. issue 1-2. 1995-10-10. PMID:7663983. |
levodopa or d2 agonist induced dyskinesia in mptp monkeys: correlation with changes in dopamine and gabaa receptors in the striatopallidal complex. |
1995-10-10 |
2023-08-12 |
monkey |
| N Seiler, C Grauffel, J Elands, M van den Buuse, B Knödgen, S Sarhan, P Moran, S Gobaill. Suppression of haloperidol-induced oral dyskinesias in rats by vigabatrin. Pharmacology, biochemistry, and behavior. vol 50. issue 2. 1995-06-02. PMID:7740056. |
acute and chronic administration of vigabatrin, a selective inactivator of gaba-t, suppresses haloperidol-induced dyskinesias at low doses without preventing the enhancement of striatal dopamine d2 receptor density or the development of vacuous chewing movements. |
1995-06-02 |
2023-08-12 |
rat |
| H Lublin, J Gerlach, L Peacoc. Chronic treatment with the D1 receptor antagonist, SCH 23390, and the D2 receptor antagonist, raclopride, in cebus monkeys withdrawn from previous haloperidol treatment. Extrapyramidal syndromes and dopaminergic supersensitivity. Psychopharmacology. vol 112. issue 2-3. 1995-03-30. PMID:7871047. |
the effects of chronic treatment with dopamine (da) d1 and d2 receptor antagonists were evaluated in eight cebus apella monkeys with mild oral dyskinesia after previous haloperidol treatment. |
1995-03-30 |
2023-08-12 |
monkey |
| J L Neisewander, E Castañeda, D A Davi. Dose-dependent differences in the development of reserpine-induced oral dyskinesia in rats: support for a model of tardive dyskinesia. Psychopharmacology. vol 116. issue 1. 1995-03-23. PMID:7862934. |
the disruption of dopamine neurotransmission may be involved in development of the oral dyskinesia. |
1995-03-23 |
2023-08-12 |
rat |
| P J Blanchet, R Boucher, P J Bédar. Excitotoxic lateral pallidotomy does not relieve L-dopa-induced dyskinesia in MPTP parkinsonian monkeys. Brain research. vol 650. issue 1. 1994-12-07. PMID:7953674. |
when l-dopa treatment was resumed or instituted 1 week postoperatively, ipsiversive circling behavior occurred in all animals and contralateral dyskinesia worsened in 3, whether l-dopa or a selective dopamine d2 agonist was administered. |
1994-12-07 |
2023-08-12 |
monkey |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
basal ganglia gabaa and dopamine d1 binding site correlates of haloperidol-induced oral dyskinesias in rat. |
1994-07-07 |
2023-08-12 |
rat |
| M R Luquin, J Guillén, E Martínez-Vila, J Laguna, J M Martínez-Lag. Functional interaction between dopamine D1 and D2 receptors in 'MPTP' monkeys. European journal of pharmacology. vol 253. issue 3. 1994-07-05. PMID:7911084. |
pretreatment with the dopamine d1 receptor antagonist sch 23390 (0.8 mg/kg) and the dopamine d2 receptor antagonist sulpiride (60 mg/kg) reduced the magnitude and the duration of the motor response induced by (+)-phno and cy 208-243, respectively, but did not modify the intensity and characteristics of choreic dyskinesias. |
1994-07-05 |
2023-08-12 |
monkey |
| M R Luquin, J Guillén, E Martínez-Vila, J Laguna, J M Martínez-Lag. Functional interaction between dopamine D1 and D2 receptors in 'MPTP' monkeys. European journal of pharmacology. vol 253. issue 3. 1994-07-05. PMID:7911084. |
these results demonstrate that the motor effects and the dyskinesias cannot be dissociated by selective dopamine d1 and d2 receptor stimulation. |
1994-07-05 |
2023-08-12 |
monkey |
| C Gagnon, B Gomez-Mancilla, P J Bédard, T Di Paol. Chronic CY 208-243 treatment of MPTP-monkeys causes regional changes of dopamine and GABAA receptors. Neuroscience letters. vol 163. issue 1. 1994-03-02. PMID:7905197. |
dopamine levels were more decreased in the striatum of mptp-monkeys with dyskinesias compared to those without dyskinesias. |
1994-03-02 |
2023-08-12 |
monkey |
| B Glenthøj, T G Bolwig, R Hemmingse. Effects of chronic discontinuous and continuous treatment of rats with a dopamine D1 receptor antagonist (NNC-756). European journal of pharmacology. vol 242. issue 3. 1994-02-14. PMID:8281992. |
the present study suggests that treatment with selective dopamine d1 receptor antagonists is less likely to cause irreversible oral dyskinesia than is treatment with classical neuroleptic drugs. |
1994-02-14 |
2023-08-12 |
rat |
| R E Se. Assessment of striatal extracellular dopamine and dopamine metabolites by microdialysis in haloperidol-treated rats exhibiting oral dyskinesia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 9. issue 2. 1993-12-01. PMID:8216693. |
assessment of striatal extracellular dopamine and dopamine metabolites by microdialysis in haloperidol-treated rats exhibiting oral dyskinesia. |
1993-12-01 |
2023-08-12 |
rat |
| P Blanchet, P J Bédard, D R Britton, J W Kebabia. Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys. The Journal of pharmacology and experimental therapeutics. vol 267. issue 1. 1993-11-29. PMID:7901395. |
four 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-exposed parkinsonian monkeys already exhibiting levodopa- and dopamine agonist-induced dyskinesia received selective d-1 agonists ([2,3,4,5-tetrahydro-7-8-dihydroxy-1-phenyl-1-h-3-benzazepine- hci] (skf 38393), [(+-)6-chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro- 1h-3-benzazepine hydrobromide] (skf 82958), [(1r, 3s)3-(1'-adamantyl)-1-aminomethyl-3,4-dihydro-5,6- dihydroxy-1h-2-benzopyran hydrochloride] (a-77636) and [(-)-(6ar)(12br)-4,6,6a,7,8,12b-hexahydro-7-methyli ndolo (4,3-ab)-phenanthridine] (cy 208-243)) to compare these drugs with selective d-2 agonists (ly 171555, (+)-4-propyl-9- hydroxynaphthoxazine and bromocriptine) and levodopa in terms of antiparkinsonian efficacy and side effects. |
1993-11-29 |
2023-08-12 |
monkey |
| b' A F Iakimovski\\xc4\\xa. [The effect of the activation and blockade of the neostriatal dopaminergic system on the hyperkinesis evoked in rats by the intrastriatal administration of picrotoxin]. Biulleten\' eksperimental\'noi biologii i meditsiny. vol 116. issue 7. 1993-10-28. PMID:8400197.' |
the role of the striatal gaba and dopamine systems in neuromotor dyskinesias and their functional relationship are discussed. |
1993-10-28 |
2023-08-12 |
rat |
| D Bravi, T L Davis, M M Mouradian, T N Chas. Treatment of Parkinson's disease with the partial dopamine agonist EMD 49980. Movement disorders : official journal of the Movement Disorder Society. vol 8. issue 2. 1993-05-18. PMID:8097280. |
emd 49980 monotherapy resulted in a mild improvement in parkinsonian symptoms, but when co-administered with levodopa, had no significant effect on dyskinesias or on the antiparkinsonian effect of the dopamine precursor. |
1993-05-18 |
2023-08-12 |
Not clear |
| D Bravi, T L Davis, M M Mouradian, T N Chas. Treatment of Parkinson's disease with the partial dopamine agonist EMD 49980. Movement disorders : official journal of the Movement Disorder Society. vol 8. issue 2. 1993-05-18. PMID:8097280. |
these results suggest that emd 49980 exerts a net weak dopamine agonist effect but fails to ameliorate levodopa-induced dyskinesias. |
1993-05-18 |
2023-08-12 |
Not clear |
| D C Mash, C P Zabetia. Sigma receptors are associated with cortical limbic areas in the primate brain. Synapse (New York, N.Y.). vol 12. issue 3. 1993-02-11. PMID:1481139. |
novel antipsychotic agents which possess selective and high affinity for sigma binding sites may serve as an alternative to the principal neuroleptic drugs currently in clinical use which mediate extrapyramidal side effects and dyskinesias through their blockade of dopamine receptors. |
1993-02-11 |
2023-08-11 |
monkey |
| H Lublin, J Gerlach, L Peacoc. Effect of D1 and D2 agonists in primates withdrawn from long-term treatment with haloperidol: the potential role of dopamine D1 receptors in dyskinesia. Clinical neuropharmacology. vol 15. issue 6. 1993-02-09. PMID:1362136. |
effect of d1 and d2 agonists in primates withdrawn from long-term treatment with haloperidol: the potential role of dopamine d1 receptors in dyskinesia. |
1993-02-09 |
2023-08-11 |
monkey |