| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura Del Hoyo Soriano, Jennifer Catalina Villarreal, Audra Sterling, Jamie Edgin, Elizabeth Berry-Kravis, Debra R Hamilton, Angela John Thurman, Leonard Abbedut. The association between expressive language skills and adaptive behavior in individuals with Down syndrome. Scientific reports. vol 12. issue 1. 2022-11-21. PMID:36411304. |
the primary goal of this study was to determine whether expressive language skills contribute to adaptive behavior (e.g., socialization and daily living skills) in children, adolescents, and young adults with down syndrome (ds) whilst controlling for age and nonverbal cognitive ability. |
2022-11-21 |
2023-08-14 |
human |
| Jamile Lopes, Isabela Miziara, Danial Kahani, Rodolfo Parreira, Daniela Fonseca, Roberta Lazzari, Lorraine Cordeiro, Eduardo Naves, Veronica Cimolin, Manuela Galli, Bernard Conway, Claudia Oliveir. Brain wave behavior in children with down syndrome following cortical neuromodulation combined with sensorimotor stimulation: observational study. Physiotherapy theory and practice. 2022-11-17. PMID:36384401. |
individuals with down syndrome (ds) require more time to develop motor and/or cognitive skills. |
2022-11-17 |
2023-08-14 |
Not clear |
| Xu-Qiao Chen, Xinxin Zuo, Ann Becker, Elizabeth Head, William C Moble. Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-11-12. PMID:36370135. |
though people with down syndrome (ds) are at markedly increased risk for ad (ad-ds), few studies have addressed synapse dysfunction. |
2022-11-12 |
2023-08-14 |
mouse |
| Bani Bandana Ganguly, Nitin N Kada. Therapeutics for mitochondrial dysfunction-linked diseases in Down syndrome. Mitochondrion. 2022-11-12. PMID:36371073. |
genome-wide deregulation contributes to mitochondrial dysfunction and impairment in oxidative phosphorylation (oxphos) mechanism resulting in oxidative stress, increased production of reactive oxygen species (ros) and cell death in individuals with down syndrome (ds). |
2022-11-12 |
2023-08-14 |
mouse |
| Jasneek K Chawla, Emma Cooke, Maria Carmen Miguel, Scott Burgess, Sally Stato. Parents' Experiences of Having a Child with Down Syndrome and Sleep Difficulties. Behavioral sleep medicine. 2022-11-11. PMID:36368334. |
sleep disorders are prevalent in children with down syndrome (ds). |
2022-11-11 |
2023-08-14 |
Not clear |
| Mariana Martins, Paulo Mascarenhas, José Grillo Evangelista, Isabel Barahona, Vitor Tavare. The Incidence of Dental Caries in Children with Down Syndrome: A Systematic Review and Meta-Analysis. Dentistry journal. vol 10. issue 11. 2022-11-10. PMID:36354650. |
scientific evidence regarding the incidence of dental caries in down syndrome (ds) patients is limited and sometimes presents divergent opinions among authors, making it difficult to reach definitive conclusions. |
2022-11-10 |
2023-08-14 |
Not clear |
| Maurike Dorothea de Groot-van der Mooren, Brigitta Catharina Scheerman, Lukas Augustinus Johannes Rammeloo, Hester van Wieringen, Anne-Marie van Wermeskerken, Roos van der Plas, Peter de Winter, Michel Emile Weijerman, Martina Cornelia Cornel, Anton Hubertus van Kaa. Neonatal mortality and morbidity in Down syndrome in the time of prenatal aneuploidy testing: a retrospective cohort study. European journal of pediatrics. 2022-11-09. PMID:36350406. |
the total uptake of prenatal aneuploidy screening for down syndrome (ds) is increasing worldwide. |
2022-11-09 |
2023-08-14 |
Not clear |
| Luigi D Notarangelo, Marita Bosticard. Interferons in Down syndrome: When more is less. Immunity. vol 55. issue 11. 2022-11-09. PMID:36351368. |
individuals with down syndrome (ds) are at a lower risk for viral infections than the general population, yet their infectious episodes are often more serious. |
2022-11-09 |
2023-08-14 |
Not clear |
| Alberto Fernández, Federico Ramírez-Toraño, Ricardo Bruña, Pilar Zuluaga, Susanna Esteba-Castillo, Daniel Abásolo, Fernando Moldenhauer, Elizabeth Shumbayawonda, Fernando Maestú, Javier García-Alb. Brain signal complexity in adults with Down syndrome: Potential application in the detection of mild cognitive impairment. Frontiers in aging neuroscience. vol 14. 2022-11-07. PMID:36337705. |
down syndrome (ds) is considered the most frequent cause of early-onset alzheimer's disease (ad), and the typical pathophysiological signs are present in almost all individuals with ds by the age of 40. |
2022-11-07 |
2023-08-14 |
Not clear |
| Carlo Condello, Alison M Maxwell, Erika Castillo, Atsushi Aoyagi, Caroline Graff, Martin Ingelsson, Lars Lannfelt, Thomas D Bird, C Dirk Keene, William W Seeley, Daniel P Perl, Elizabeth Head, Stanley B Prusine. Aβ and tau prions feature in the neuropathogenesis of Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 46. 2022-11-07. PMID:36343257. |
down syndrome (ds) is caused by the triplication of chromosome 21 and is the most common chromosomal disorder in humans. |
2022-11-07 |
2023-08-14 |
Not clear |
| Han Kang, Lingxi Wang, Xingyu Li, Chonglan Gao, Yamei Xie, Yu H. Application of chromosome microarray analysis and karyotyping in diagnostic assessment of abnormal Down syndrome screening results. BMC pregnancy and childbirth. vol 22. issue 1. 2022-11-05. PMID:36333674. |
down syndrome (ds) is the most common congenital cause of intellectual disability and also leads to numerous metabolic and structural problems. |
2022-11-05 |
2023-08-14 |
Not clear |
| Hülya Özbeşer, Emine Handan Tüzün, Burcu Dericioğlu, Çisel Demiralp Övgü. Effects of Cognitive Orientation to Daily Occupational Performance and Conductive Education Treatment Approaches on Fine Motor Skills, Activity and Participation Limitations in Children with Down Syndrome: A Randomised Controlled Trial. Journal of autism and developmental disorders. 2022-11-03. PMID:36323991. |
this study aiming to compare the effectiveness of cognitive orientation to daily occupational performance (co-op) and conductive education (ce) approaches on motor skills, activity limitation and participation restrictions in children with down syndrome (ds). |
2022-11-03 |
2023-08-14 |
Not clear |
| Peter Lauffer, Nitash Zwaveling-Soonawala, Shaobo Li, Maria G Bacalini, Oxana Y Naumova, Joseph Wiemels, Anita Boelen, Peter Henneman, Adam J de Smith, A S Paul van Trotsenbur. Meta-analysis of DNA methylation datasets shows aberrant DNA methylation of thyroid development or function genes in Down syndrome. Thyroid : official journal of the American Thyroid Association. 2022-11-03. PMID:36326208. |
in down syndrome (ds) there is a high occurrence of congenital hypothyroidism (ch) and subclinical hypothyroidism (sh) early in life. |
2022-11-03 |
2023-08-14 |
Not clear |
| Kevin Callans, Diane L Carroll, Annette McDonoug. Parental experience of hypoglossal nerve stimulator implantation in adolescents with Down Syndrome and obstructive sleep apnea. Journal of pediatric nursing. 2022-11-03. PMID:36328914. |
the purpose of this study is to explore the experience of parents in deciding whether to participate in a clinical trial of the insertion of the hypoglossal nerve stimulator (hns) to treat their adolescent with down syndrome (ds) and obstructive sleep apnea (osa). |
2022-11-03 |
2023-08-14 |
Not clear |
| Angela Militi, Riccardo Nucera, Giusy Chirieleison, Luca Fiorillo, Gabriele Cervino, Marco Portell. Down Syndrome children with obstructive sleep apnea. Minerva dental and oral science. vol 71. issue 5. 2022-11-02. PMID:36321622. |
obstructive sleep apnea syndrome (osas) is a complex disorder with significant clinical consequences for people with down syndrome (ds). |
2022-11-02 |
2023-08-14 |
Not clear |
| Vishi Sharma, Sunita Nehra, Long H Do, Anwesha Ghosh, Aniruddha J Deshpande, Nishant Singha. Biphasic cell cycle defect causes impaired neurogenesis in down syndrome. Frontiers in genetics. vol 13. 2022-10-31. PMID:36313423. |
impaired neurogenesis in down syndrome (ds) is characterized by reduced neurons, increased glial cells, and delayed cortical lamination. |
2022-10-31 |
2023-08-14 |
mouse |
| Laura Del Hoyo Soriano, Audra Sterling, Jamie Edgin, Debra R Hamilton, Elizabeth Berry-Kravis, Amanda Dimachkie Nunnally, Angela John Thurman, Leonard Abbedut. Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome. Journal of autism and developmental disorders. 2022-10-31. PMID:36315322. |
this study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (iq) to autism symptom presentation in down syndrome (ds). |
2022-10-31 |
2023-08-14 |
human |
| Iulia Ioan, Diane Weick, François Sevin, Damien Sanlaville, Bénédicte De Fréminville, Cyril Schweitzer, Mohamed Akkari, Laurianne Coutier, Benjamin Putois, Sabine Plancoulaine, Marine Thieux, Patricia Franc. Neurocognitive evaluation of children with down syndrome and obstructive sleep apnea syndrome. Sleep medicine. vol 100. 2022-10-29. PMID:36308912. |
early osas diagnosis in children with down syndrome (ds) would be important to prevent its complications, especially cognitive ones, but remains overlooked. |
2022-10-29 |
2023-08-14 |
Not clear |
| Marie Moore Channell, Linnea E Sandstrom, Danielle Harve. Mental State Language Development in Children With Down Syndrome Versus Typical Development. American journal on intellectual and developmental disabilities. vol 127. issue 6. 2022-10-28. PMID:36306411. |
used by 6- to 11-year-old children with down syndrome (ds) to a younger typically developing (td) comparison group matched by nonverbal cognition. |
2022-10-28 |
2023-08-14 |
Not clear |
| Kaylyn Van Deusen, Mark A Prince, Anna J Esbensen, Jamie O Edgin, Emily K Schworer, Angela John Thurman, Lina R Patel, Lisa A Daunhauer, Deborah J Fidle. Profiles of Caregiver-Reported Executive Function in Children with Down Syndrome. Brain sciences. vol 12. issue 10. 2022-10-27. PMID:36291267. |
children with down syndrome (ds) are at risk for challenges with aspects of executive function (ef). |
2022-10-27 |
2023-08-14 |
human |