| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Omer Schwartzman, Angela Maria Savino, Michael Gombert, Chiara Palmi, Gunnar Cario, Martin Schrappe, Cornelia Eckert, Arend von Stackelberg, Jin-Yan Huang, Michal Hameiri-Grossman, Smadar Avigad, Geertruy Te Kronnie, Ifat Geron, Yehudit Birger, Avigail Rein, Giulia Zarfati, Ute Fischer, Zohar Mukamel, Martin Stanulla, Andrea Biondi, Giovanni Cazzaniga, Amedeo Vetere, Bridget K Wagner, Zhu Chen, Sai-Juan Chen, Amos Tanay, Arndt Borkhardt, Shai Izrael. Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 20. 2018-05-15. PMID:28461505. |
children with down syndrome (ds) are prone to development of high-risk b-cell precursor all (ds-all), which differs genetically from most sporadic pediatric alls. |
2018-05-15 |
2023-08-13 |
Not clear |
| b' Susana Garc\\xc3\\xada-Cerro, Noem\\xc3\\xad Rueda, Ver\\xc3\\xb3nica Vidal, Sara Lantigua, Carmen Mart\\xc3\\xadnez-Cu\\xc3\\xa. Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer\'s disease phenotypes. Neurobiology of disease. vol 106. 2018-05-15. PMID:28647555.' |
the intellectual disability that characterizes down syndrome (ds) is primarily caused by prenatal changes in central nervous system growth and differentiation. |
2018-05-15 |
2023-08-13 |
mouse |
| Vincenzo Roncacé, Costanza Burattini, Fiorenza Stagni, Sandra Guidi, Andrea Giacomini, Marco Emili, Giorgio Aicardi, Renata Bartesagh. Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome. Neurobiology of disease. vol 106. 2018-05-15. PMID:28651891. |
down syndrome (ds), a genetic condition due to triplication of chromosome 21, is characterized by numerous neurodevelopmental alterations and intellectual disability. |
2018-05-15 |
2023-08-13 |
mouse |
| Angela Natalie Barrett, Henna Vishal Advani, Lyn S Chitty, Lin Lin Su, Arijit Biswas, Wei Ching Tan, Melissa Hill, Mahesh Choolan. Evaluation of preferences of women and healthcare professionals in Singapore for implementation of noninvasive prenatal testing for Down syndrome. Singapore medical journal. vol 58. issue 6. 2018-05-14. PMID:27357315. |
invasive prenatal diagnosis (ipd) has long been used to prenatally diagnose down syndrome (ds), but it is associated with a small risk of miscarriage. |
2018-05-14 |
2023-08-13 |
Not clear |
| Rima Obeid, Ulrich Hübner, Marion Bodis, Juergen Geise. Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. Neuromolecular medicine. vol 18. issue 4. 2018-05-10. PMID:27234618. |
premature aging and disturbed methylation are components of down syndrome (ds). |
2018-05-10 |
2023-08-13 |
human |
| Soujanya Bogarapu, Nelangi M Pinto, Susan P Etheridge, Xiaoming Sheng, Kirk N Liesemer, Paul C Young, Elizabeth V Saare. Screening for Congenital Heart Disease in Infants with Down Syndrome: Is Universal Echocardiography Necessary? Pediatric cardiology. vol 37. issue 7. 2018-05-10. PMID:27278630. |
current guidelines recommend that all neonates with down syndrome (ds) be screened for congenital heart disease (chd) with an echocardiogram. |
2018-05-10 |
2023-08-13 |
Not clear |
| Ewa Puszczałowska-Lizis, Krzysztof Nowak, Jarosław Omorczyk, Tadeusz Ambroży, Przemysław Bujas, Leszek Nosiade. Foot Structure in Boys with Down Syndrome. BioMed research international. vol 2017. 2018-05-09. PMID:28904967. |
down syndrome (ds) is associated with numerous developmental abnormalities, some of which cause dysfunctions of the posture and the locomotor system. |
2018-05-09 |
2023-08-13 |
Not clear |
| David G Ingram, Amanda G Ruiz, Dexiang Gao, Norman R Friedma. Success of Tonsillectomy for Obstructive Sleep Apnea in Children With Down Syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 13. issue 8. 2018-05-08. PMID:28728615. |
obstructive sleep apnea (osa) is common in children with down syndrome (ds) and associated with significant morbidity. |
2018-05-08 |
2023-08-13 |
Not clear |
| Nanda C de Knegt, Frank Lobbezoo, Carlo Schuengel, Heleen M Evenhuis, Erik J A Scherde. Self-Reported Presence and Experience of Pain in Adults with Down Syndrome. Pain medicine (Malden, Mass.). vol 18. issue 7. 2018-05-07. PMID:27694149. |
the aim was to examine whether the presence of pain (based on physical conditions and participants' report) and self-reported pain experience in adults with down syndrome (ds) differ from general population controls. |
2018-05-07 |
2023-08-13 |
human |
| Nanda C de Knegt, Frank Lobbezoo, Carlo Schuengel, Heleen M Evenhuis, Erik J A Scherde. Pain and Cognitive Functioning in Adults with Down Syndrome. Pain medicine (Malden, Mass.). vol 18. issue 7. 2018-05-07. PMID:28034975. |
the aim of the present study was to examine whether cognitive functioning (i.e., memory and executive functioning) is related to self-reported presence of pain (i.e., affirmative answer to the question whether the individual feels pain) and experience of pain (i.e., intensity and affect) in adults with down syndrome (ds). |
2018-05-07 |
2023-08-13 |
Not clear |
| Lisa L Hunter, Douglas H Keefe, M Patrick Feeney, David K Brown, Jareen Meinzen-Derr, Alaaeldin M Elsayed, Julia M Amann, Vairavan Manickam, Denis Fitzpatrick, Sally R Shot. Wideband acoustic immittance in children with Down syndrome: prediction of middle-ear dysfunction, conductive hearing loss and patent PE tubes. International journal of audiology. vol 56. issue 9. 2018-05-07. PMID:28434272. |
the purpose of this study was to evaluate pressurised wideband acoustic immittance (wai) tests in children with down syndrome (ds) and in typically developing children (td) for prediction of conductive hearing loss (chl) and patency of pressure equalising tubes (pets). |
2018-05-07 |
2023-08-13 |
Not clear |
| Kazuaki Yasuoka, Hirosuke Inoue, Koichi Tanaka, Junko Fujiyoshi, Yuki Matsushita, Masayuki Ochiai, Yuhki Koga, Toshiharu Matsuura, Tomoaki Taguchi, Shouichi Ohg. Successful Liver Transplantation for Transient Abnormal Myelopoiesis-Associated Liver Failure. Neonatology. vol 112. issue 2. 2018-05-07. PMID:28558383. |
infants with down syndrome (ds) are at risk of developing a transient abnormal myelopoiesis (tam). |
2018-05-07 |
2023-08-13 |
Not clear |
| Sébastien A Gauthier, Rocío Pérez-González, Ajay Sharma, Fang-Ke Huang, Melissa J Alldred, Monika Pawlik, Gurjinder Kaur, Stephen D Ginsberg, Thomas A Neubert, Efrat Lev. Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities. Acta neuropathologica communications. vol 5. issue 1. 2018-05-07. PMID:28851452. |
a dysfunctional endosomal pathway and abnormally enlarged early endosomes in neurons are an early characteristic of down syndrome (ds) and alzheimer's disease (ad). |
2018-05-07 |
2023-08-13 |
mouse |
| Patrick M Cowley, Divya R Nair, Lara R DeRuisseau, Stefan Keslacy, Mustafa Atalay, Keith C DeRuissea. Oxidant production and SOD1 protein expression in single skeletal myofibers from Down syndrome mice. Redox biology. vol 13. 2018-05-03. PMID:28697486. |
down syndrome (ds) is a genetic condition caused by the triplication of chromosome 21. |
2018-05-03 |
2023-08-13 |
mouse |
| S J Loveall, F A Conners, A S Tungate, L J Hahn, T D Oss. A cross-sectional analysis of executive function in Down syndrome from 2 to 35 years. Journal of intellectual disability research : JIDR. vol 61. issue 9. 2018-05-01. PMID:28726285. |
previous research has indicated a unique profile of executive function (ef) in children and adolescents with down syndrome (ds). |
2018-05-01 |
2023-08-13 |
Not clear |
| Silvia Lanfranchi, Francesca Pulina, Barbara Carretti, Irene C Mammarell. Training spatial-simultaneous working memory in individuals with Down syndrome. Research in developmental disabilities. vol 64. 2018-04-25. PMID:28388504. |
recent studies have suggested that the spatial-simultaneous component of working memory (wm), which is involved when stimuli are presented simultaneously, is selectively impaired in individuals with down syndrome (ds). |
2018-04-25 |
2023-08-13 |
Not clear |
| Lucy Wilde, Kate Eden, Petrus de Vries, Jo Moss, Alice Welham, Chris Olive. Self-injury and aggression in adults with tuberous sclerosis complex: Frequency, associated person characteristics, and implications for assessment. Research in developmental disabilities. vol 64. 2018-04-25. PMID:28411579. |
this study determined the caregiver-reported frequency of self-injury and aggression in adults with tsc plus id in comparison to down syndrome (ds) and angelman syndrome (as), and assessed demographic and behavioural characteristics associated with the occurrence of each behaviour in tsc. |
2018-04-25 |
2023-08-13 |
Not clear |
| b' Samire Beqaj, Njomza Jusaj, Vujica \\xc5\\xbdivkovi\\xc4\\x8. Attainment of gross motor milestones in children with Down syndrome in Kosovo - developmental perspective. Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina. vol 14. issue 2. 2018-04-25. PMID:28786971.' |
aim to investigate the age (in months) at which motor skills are developed in children with down syndrome (ds), and compare it to the age of the development of the same skills in both, children with typical development (td), and children with ds reported by four other studies. |
2018-04-25 |
2023-08-13 |
Not clear |
| Talita Maria Monteiro Farias Barbosa, Ivonaldo Leidson Barbosa Lima, Giorvan Ânderson Dos Santos Alves, Isabelle Cahino Delgad. Contributions of speech-language therapy to the integration of individuals with Down syndrome in the workplace. CoDAS. vol 30. issue 1. 2018-04-25. PMID:29513864. |
to analyze the contributions of speech-language therapy in the integration of young individuals with down syndrome (ds) into the workplace, with reference to their professionalization. |
2018-04-25 |
2023-08-13 |
Not clear |
| Jianxing Xiang, Su Yang, Ning Xin, Marta A Gaertig, Roger H Reeves, Shihua Li, Xiao-Jiang L. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 7. 2018-04-24. PMID:28137862. |
moreover, we found that hap1 bound dcaf7 competitively in cytoplasm with dual-specificity tyrosine phosphorylation-regulated kinase 1a (dyrk1a), a protein implicated in down syndrome (ds). |
2018-04-24 |
2023-08-13 |
mouse |