| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hu-Jiang Shi, Yi-Ren Xue, Hua Shao, Cheng Wei, Ting Liu, Jie He, Yu-Hao Yang, Hong-Mei Wang, Na Li, Si-Qiang Ren, Lei Chang, Zhen Wang, Li-Juan Zh. Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours. Brain : a journal of neurology. 2024-05-03. PMID:38701344. |
the implication of 5-hydroxytryptamine 2c receptor (5-ht2cr) in depression is a topic of debate, and the underlying mechanisms remain largely unclear. |
2024-05-03 |
2024-05-06 |
Not clear |
| M Gärde, G J Matheson, K Varnäs, P Svenningsson, E Hedman-Lagerlöf, J Lundberg, L Farde, M Tige. Altered serotonin 1B receptor binding after escitalopram for depression is correlated with treatment effect. The international journal of neuropsychopharmacology. 2024-05-02. PMID:38695786. |
altered serotonin 1b receptor binding after escitalopram for depression is correlated with treatment effect. |
2024-05-02 |
2024-05-04 |
human |
| Bartosz Bobula, Magdalena Kusek, Grzegorz Hes. The 5-HT Pharmacology, biochemistry, and behavior. 2024-04-30. PMID:38688436. |
the 5-ht the use of a selective serotonin reuptake inhibitor fluoxetine in depression during pregnancy and the postpartum period might increase the risk of affective disorders and cognitive symptoms in progeny. |
2024-04-30 |
2024-05-03 |
mouse |
| Ying Yang, Ying Lai, Xueli Tong, Zipei Li, Yuanyuan Cheng, Li-Wen Tia. Arjunolic acid ameliorates lipopolysaccharide-induced depressive behavior by inhibiting neuroinflammation via microglial SIRT1/AMPK/Notch1 signaling pathway. Journal of ethnopharmacology. 2024-04-26. PMID:38670408. |
neuroinflammation is involved in the pathogenesis of depression disorder by activating microglia cells, increasing proinflammatory cytokines, effecting serotonin synthesis and metabolism, and neuronal apoptosis and neurogenesis. |
2024-04-26 |
2024-04-29 |
Not clear |
| Jolanda Malamud, Gemma Lewis, Michael Moutoussis, Larisa Duffy, Jessica Bone, Ramya Srinivasan, Glyn Lewis, Quentin J M Huy. The selective serotonin reuptake inhibitor sertraline alters learning from aversive reinforcements in patients with depression: evidence from a randomized controlled trial. Psychological medicine. 2024-04-17. PMID:38629200. |
the selective serotonin reuptake inhibitor sertraline alters learning from aversive reinforcements in patients with depression: evidence from a randomized controlled trial. |
2024-04-17 |
2024-04-19 |
Not clear |
| Jolanda Malamud, Gemma Lewis, Michael Moutoussis, Larisa Duffy, Jessica Bone, Ramya Srinivasan, Glyn Lewis, Quentin J M Huy. The selective serotonin reuptake inhibitor sertraline alters learning from aversive reinforcements in patients with depression: evidence from a randomized controlled trial. Psychological medicine. 2024-04-17. PMID:38629200. |
selective serotonin reuptake inhibitors (ssris) are first-line pharmacological treatments for depression and anxiety. |
2024-04-17 |
2024-04-19 |
Not clear |
| Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth, Modi Niharika, Negi Preeya, Islam Rezau. Molecular Docking, MM-GBSA, and Molecular Dynamics Approach: 5-MeO-DMT Analogues as Potential Antidepressants. Archives of Razi Institute. vol 78. issue 5. 2024-04-09. PMID:38590677. |
according to the monoamine-deficiency hypothesis, the underlying pathophysiology of depression is a deficiency of some neurotransmitters (serotonin, norepinephrine, or dopamine) in the central nervous system. |
2024-04-09 |
2024-04-11 |
Not clear |
| Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth, Modi Niharika, Negi Preeya, Islam Rezau. Molecular Docking, MM-GBSA, and Molecular Dynamics Approach: 5-MeO-DMT Analogues as Potential Antidepressants. Archives of Razi Institute. vol 78. issue 5. 2024-04-09. PMID:38590677. |
the neurotransmitter serotonin has drawn the most attention concerning depression. |
2024-04-09 |
2024-04-11 |
Not clear |
| Mai M Anwar, Ibrahim M Ibrahim Lail. The ameliorating effect of Rutin on hepatotoxicity and inflammation induced by the daily administration of vortioxetine in rats. BMC complementary medicine and therapies. vol 24. issue 1. 2024-04-08. PMID:38581023. |
vortioxetine (vortx) is a potent and selective type of selective serotonin reuptake inhibitor (ssri) that is mainly prescribed for treating major depression along with mood disorders as the first drug of choice. |
2024-04-08 |
2024-04-10 |
rat |
| Samineh Nasseri, Shadi Hajrasouliha, Salar Vaseghi, Batool Ghorbani Yekt. Interaction effect of crocin and citalopram on memory and locomotor activity in rats: an insight into BDNF and synaptophysin levels in the hippocampus. Naunyn-Schmiedeberg's archives of pharmacology. 2024-04-03. PMID:38568290. |
selective serotonin reuptake inhibitors (ssris) are widely used drugs for the treatment of depression. |
2024-04-03 |
2024-04-05 |
rat |
| Nastaran Talaee, Shataw Azadvar, Sanaz Khodadadi, Nahal Abbasi, Zahra Najafi Asli-Pashaki, Yasaman Mirabzadeh, Gita Kholghi, Shahin Akhondzadeh, Salar Vasegh. Comparing the effect of fluoxetine, escitalopram, and sertraline, on the level of BDNF and depression in preclinical and clinical studies: a systematic review. European journal of clinical pharmacology. 2024-04-01. PMID:38558317. |
it seems that selective serotonin reuptake inhibitors (ssris) improve depression via affecting bdnf level. |
2024-04-01 |
2024-04-04 |
human |
| Zainab Zakaraya, Mohammad Abu Assab, Lina N Tamimi, Nida Karameh, Mohammad Hailat, Laila Al-Omari, Wael Abu Dayyih, Omar Alasasfeh, Mohammad Awad, Riad Awa. Pharmacokinetics and Pharmacodynamics: A Comprehensive Analysis of the Absorption, Distribution, Metabolism, and Excretion of Psychiatric Drugs. Pharmaceuticals (Basel, Switzerland). vol 17. issue 3. 2024-03-28. PMID:38543065. |
it is noteworthy that the inclusion of selective serotonin reuptake inhibitors (ssris) and serotonin-norepinephrine reuptake inhibitors (snris) in a comprehensive depression management protocol may demonstrate enhanced effectiveness in clinical environments as opposed to controlled trials. |
2024-03-28 |
2024-03-30 |
human |
| Iseline Cardon, Sonja Grobecker, Frederike Jenne, Tatjana Jahner, Rainer Rupprecht, Vladimir M Milenkovic, Christian H Wetze. Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression. Molecular psychiatry. 2024-03-27. PMID:38532010. |
serotonin effects on human ipsc-derived neural cell functions: from mitochondria to depression. |
2024-03-27 |
2024-03-29 |
human |
| Iseline Cardon, Sonja Grobecker, Frederike Jenne, Tatjana Jahner, Rainer Rupprecht, Vladimir M Milenkovic, Christian H Wetze. Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression. Molecular psychiatry. 2024-03-27. PMID:38532010. |
depression's link to serotonin dysregulation is well-known. |
2024-03-27 |
2024-03-29 |
human |
| Iseline Cardon, Sonja Grobecker, Frederike Jenne, Tatjana Jahner, Rainer Rupprecht, Vladimir M Milenkovic, Christian H Wetze. Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression. Molecular psychiatry. 2024-03-27. PMID:38532010. |
the monoamine theory posits that depression results from impaired serotonin activity, leading to the development of antidepressants targeting serotonin levels. |
2024-03-27 |
2024-03-29 |
human |
| S Meltzer-Brody, M E Gerbasi, C Mak, Y Toubouti, S Smith, N Roskell, R Tan, S Chen, K M Deligiannidi. Indirect comparisons of relative efficacy estimates of zuranolone and selective serotonin reuptake inhibitors for postpartum depression. Journal of medical economics. 2024-03-25. PMID:38523596. |
indirect comparisons of relative efficacy estimates of zuranolone and selective serotonin reuptake inhibitors for postpartum depression. |
2024-03-25 |
2024-03-27 |
Not clear |
| Lina Bukowski, Markus Emanuel Strøm, Jens Lindengren Andersen, Jannick Bang Maesen, Lin Tian, Steffen Sinnin. 5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release. Scientific reports. vol 14. issue 1. 2024-03-20. PMID:38504103. |
the neurotransmitter serotonin plays a pivotal role in mood and depression. |
2024-03-20 |
2024-03-23 |
Not clear |
| Jacob J Crouse, Shin Ho Park, Enda M Byrne, Brittany L Mitchell, Karina Chan, Jan Scott, Sarah E Medland, Nicholas G Martin, Naomi R Wray, Ian B Hicki. Evening Chronotypes With Depression Report Poorer Outcomes of Selective Serotonin Reuptake Inhibitors: A Survey-Based Study of Self-Ratings. Biological psychiatry. 2024-03-14. PMID:38185236. |
evening chronotypes with depression report poorer outcomes of selective serotonin reuptake inhibitors: a survey-based study of self-ratings. |
2024-03-14 |
2024-03-16 |
Not clear |
| Svenja Bremshey, Juliana Groß, Kim Renken, Olivia Andrea Massec. The role of serotonin in depression-A historical roundup and future directions. Journal of neurochemistry. 2024-03-13. PMID:38477031. |
in this narrative review, we aim to contribute to the ongoing debate on the involvement of serotonin in depression. |
2024-03-13 |
2024-03-15 |
Not clear |
| Lasair O'Callaghan, Elizabeth Chertavian, Scott J Johnson, Erin Ferries, Kristina M Deligiannidi. The cost-effectiveness of zuranolone versus selective serotonin reuptake inhibitors for the treatment of postpartum depression in the United States. Journal of medical economics. 2024-03-11. PMID:38465615. |
the cost-effectiveness of zuranolone versus selective serotonin reuptake inhibitors for the treatment of postpartum depression in the united states. |
2024-03-11 |
2024-03-14 |
Not clear |