| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E C Si, H U Bryant, G K Yi. Opioid and non-opioid components of insulin-induced feeding. Pharmacology, biochemistry, and behavior. vol 24. issue 4. 1986-07-07. PMID:3520602. |
when naloxone was given only 1 hour after insulin administration, depression of food intake was not noted. |
1986-07-07 |
2023-08-11 |
rat |
| K Abe, M Oka, K Kubo, Y Takenoshita, R Fre. Response of isolated guinea pig myocardium to insulin therapy during normothermia and graded hypothermia. Resuscitation. vol 13. issue 2. 1986-04-29. PMID:2421378. |
the effect of insulin during depression na-k pump by high concentration of ouabain (g-strophanthin, 10(-5) m) was also observed. |
1986-04-29 |
2023-08-11 |
Not clear |
| S Bhimji, D V Godin, J H McNeil. Myocardial ultrastructural changes in alloxan-induced diabetes in rabbits. Acta anatomica. vol 125. issue 3. 1986-04-28. PMID:3962581. |
injection of alloxan resulted in a diabetic state characterized by increased hemoglobin glycosylation, blood and urine glucose and a significant depression of serum insulin levels. |
1986-04-28 |
2023-08-11 |
Not clear |
| A Funakoshi, K Miyazaki, H Shinozaki, Y Sako, H Ibayash. Changes in insulin secretion after secretin administration and the implications in diabetes mellitus. Endocrinologia japonica. vol 32. issue 4. 1986-03-10. PMID:3910411. |
whereas iri in healthy subjects showed a monophasic change, reaching a peak (delta iri = 43 +/- 7.3 microunits/ml, m +/- se) 5 min after secretin loading and returning to the basal level in 15 min, niddm patients on diet therapy (delta iri = 40.2 +/- 7.6 microunits/ml) showed no significant difference from the control group, but niddm patients on sulfonylurea (su) (15.5 +/- 2.4 microunits/ml) and those on insulin therapy (5.3 +/- 1.4 microunits/ml), both showed a significant depression in responsiveness. |
1986-03-10 |
2023-08-11 |
human |
| A Czernik, E M Steinmeye. [Causal analytic studies on demonstration of neuroendocrine parameters in combined hypoglycemia test in depressive subgroups]. European archives of psychiatry and neurological sciences. vol 235. issue 2. 1986-01-22. PMID:3933981. |
with the help of an analytical path structure model (causal analysis) the aim of the study was to elucidate further, in female patients with various depressive disorders, some correlations of causal interdependencies between changes both in basal secretion of anterior pituitary hormones and in their responses to the (combined) insulin tolerance test (itt) with extraneous factors--such as age, deviation from ideal body weight (in percentage), severity of depression and score in the newcastle scale (ncs)--that may influence these abnormalities. |
1986-01-22 |
2023-08-11 |
Not clear |
| P H Joubert, C P Venter, H F Joubert, I Hillebran. The effect of a 1-deoxynojirimycin derivative on post-prandial blood glucose and insulin levels in healthy black and white volunteers. European journal of clinical pharmacology. vol 28. issue 6. 1986-01-03. PMID:2933261. |
it produced a similar, significant depression of post-prandial blood glucose and insulin levels when the groups were assessed separately and when the data were pooled. |
1986-01-03 |
2023-08-11 |
human |
| F Sixel-Dietrich, F Verspohl, M Dos. Hyperinsulinemia in acute intermittent porphyria. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 17. issue 7. 1985-10-09. PMID:3897010. |
results point to the essential role of insulin for the depression of porphyrin precursor overproduction as a mediator of the "glucose effect". |
1985-10-09 |
2023-08-11 |
Not clear |
| J L Lacuara, R D Ruiz, M Fiol de Cune. Modifications evoked by piretanide in the mechanical activity of cardiovascular tissues. Canadian journal of physiology and pharmacology. vol 63. issue 4. 1985-08-20. PMID:3891047. |
magnitude of phasic contractions of isolated rat portal vein was diminished by the drug in a dose-related manner; contractile depression induced by piretanide (10(-4)m) was less in the presence of insulin (0.1 u/ml), glucose (22 mm) or pyruvate (5 mm). |
1985-08-20 |
2023-08-11 |
rat |
| V Geenen, G Langer, G Koinig, G Schönbeck, M Ansseau, R von Frenckell, S Smitz, J J Legro. Release of human neurophysin I during insulin-induced hypoglycemia in depressed patients is abolished after recovery with clomipramine treatment. Psychoneuroendocrinology. vol 10. issue 1. 1985-07-22. PMID:3889965. |
at retest during clomipramine administration, a marked clinical amelioration occurred in all patients as determined with the hamilton rating scale for depression; the hnp i response to insulin was abolished, but no effect on hnp ii concentration could be demonstrated. |
1985-07-22 |
2023-08-11 |
human |
| B Hellman, R Hällgren, H Abrahamsson, P Bergsten, C Berne, E Gylfe, P Rorsman, L Wid. The dual action of glucose on the cytosolic Ca2+ activity in pancreatic beta-cells. Demonstration of an inhibitory effect of glucose on insulin release in the mouse and man. Biomedica biochimica acta. vol 44. issue 1. 1985-06-17. PMID:3888211. |
intravenous glucose tolerance tests revealed a temporary glucose depression of the serum concentrations of insulin and c-peptide in several patients with diabetes. |
1985-06-17 |
2023-08-11 |
mouse |
| A Francavilla, A Di Leo, S Q Wu, P Ove, D Van Thiel, C Sciascia, T E Starz. Discordance between glucokinase activity and insulin and glucagon receptor changes occurring during liver regeneration in the rat. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 16 Suppl 1. 1985-05-28. PMID:6099817. |
an apparent paradox was the finding of a depression of the activity of an insulin associated enzyme, glucokinase, at a time when the number of insulin binding sites was increased. |
1985-05-28 |
2023-08-12 |
rat |
| D J Smith, R M Venable, J Collin. Separation and quantitation of insulins and related substances in bulk insulin crystals and in injectables by reversed-phase high performance liquid chromatography and the effect of temperature on the separation. Journal of chromatographic science. vol 23. issue 2. 1985-04-16. PMID:3882729. |
the official method specified in the united states pharmacopeia (usp) is a bioassay measuring the depression of blood sugar concentrations in rabbits treated with the insulin under test and the official standard. |
1985-04-16 |
2023-08-11 |
human |
| F R Kuntschen, P M Galletti, C Hahn, J J Arnulf, C Isetta, V Do. Alterations of insulin and glucose metabolism during cardiopulmonary bypass under normothermia. The Journal of thoracic and cardiovascular surgery. vol 89. issue 1. 1985-02-11. PMID:3880848. |
elevated stress hormone levels, a concomitant reduction of insulin release and insulin action, and a depression of peripheral glucose utilization, as demonstrated by glucose clamp experiments, contributed to these perturbations of glucose and insulin metabolism. |
1985-02-11 |
2023-08-11 |
Not clear |
| G D Smith, D C Swenson, E J Dodson, G G Dodson, C D Reynold. Structural stability in the 4-zinc human insulin hexamer. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 22. 1985-01-02. PMID:6390430. |
unlike the surface of the 2-zinc insulin hexamer, which possesses a shallow depression containing a zinc ion and its coordinating water molecules, the 4-zinc human insulin hexamer contains a zinc and chloride ion at the bottom of an 8-a tunnel produced by three parallel alpha-helices. |
1985-01-02 |
2023-08-12 |
human |
| B Emmanuel, J J Kennell. Effect of propionic acid on kinetics of acetate and oleate and on plasma and milk fatty acid composition of goats. Journal of dairy science. vol 67. issue 6. 1984-09-07. PMID:6747042. |
data support the glucogenic theory that propionic acid either directly or through gluconeogenesis stimulates insulin secretion, which in turn inhibits release of fatty acids from adipose tissue, resulting in milk fat depression. |
1984-09-07 |
2023-08-12 |
Not clear |
| H Laborit, J F Bonifac. Action of adenosine on energy metabolism and on glucose-6-phosphate dehydrogenase in rat brains. Research communications in chemical pathology and pharmacology. vol 44. issue 1. 1984-06-27. PMID:6729244. |
the increased cerebral glucose concentration is perhaps a result of increased blood glucose levels, in turn resulting from the known depression of insulin release by adenosine, or from a preferential utilization of glycogen, resulting from the activation of adenylate cyclase. |
1984-06-27 |
2023-08-12 |
rat |
| A Schnabel, W Kindermann, V Steinkraus, O Salas-Fraire, G Bir. Metabolic and hormonal responses to exhaustive supramaximal running with and without beta-adrenergic blockade. European journal of applied physiology and occupational physiology. vol 52. issue 2. 1984-06-07. PMID:6143664. |
beta-blockade reduced the increases of lactate, glucose, glycerol, insulin, and growth hormone, exaggerated the depression of ffa and had no effect on cortisol. |
1984-06-07 |
2023-08-12 |
Not clear |
| D L Freerksen, N A Schroedl, C R Hartzel. Triiodothyronine depresses the NAD-linked glycerol-3-phosphate dehydrogenase activity of cultured neonatal rat heart cells. Archives of biochemistry and biophysics. vol 228. issue 2. 1984-03-12. PMID:6696442. |
the degree of depression was greater (65%) when the medium contained normal serum levels of hydrocortisone and insulin. |
1984-03-12 |
2023-08-12 |
rat |
| G S Spencer, G J Garssen, B Colenbrander, A A Macdonald, M M Bever. Glucose, growth hormone, somatomedin, cortisol and ACTH changes in the plasma of unanaesthetised pig foetuses following intravenous insulin administration in utero. Acta endocrinologica. vol 104. issue 2. 1983-12-17. PMID:6314725. |
following iv insulin administration there was a marked depression in plasma glucose (p less than 0.01), an elevation in growth hormone (p less than 0.05) and an increase in acth (p less than 0.01). |
1983-12-17 |
2023-08-12 |
Not clear |
| K C Gorray, W Y Fujimot. In vitro toxicity of alloxan for guinea pig B cells: comparison with rat B cells. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 173. issue 4. 1983-10-28. PMID:6351093. |
however, whereas the lowest concentration of the drug (1 mm) produced a significant depression in insulin release in rat islet cultures, with maximal depression occurring after exposure to 5 mm alloxan, insulin release from guinea pig cultures was not significantly depressed by 1 or 2 mm alloxan, and 5 mm alloxan treatment produced a submaximal depression. |
1983-10-28 |
2023-08-12 |
rat |