| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ma, A Xu, S Cui, M-R Sun, Y-C Xue, J-H Wan. Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress. Translational psychiatry. vol 6. issue 10. 2017-12-04. PMID:27701406. |
in cums-induced depression mice, there appear the decreases in the innervation and function of gabaergic axons and in the levels of mrnas and proteins of glutamate decarboxylase-67, vesicular gaba transporter and gaba transporter-3. |
2017-12-04 |
2023-08-13 |
mouse |
| K Ma, A Xu, S Cui, M-R Sun, Y-C Xue, J-H Wan. Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress. Translational psychiatry. vol 6. issue 10. 2017-12-04. PMID:27701406. |
our results suggest that chronic mild stress impairs gaba release and uptake by upregulating mirnas and downregulating mrnas and proteins, which may constitute the subcellular and molecular mechanisms for the lowered gaba tone in major depression. |
2017-12-04 |
2023-08-13 |
mouse |
| Luis M Franco, Jesús Q Beltrán, Jesús A Tapia, Franco Ortiz, Elías Manjarrez, Rafael Gutiérre. Differential frequency-dependent antidromic resonance of the Schaffer collaterals and mossy fibers. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25665800. |
noteworthy, block of glutamate and gaba ionotropic receptors prevented resonance and reduced the depression of antidromic responses to β/γ and γ stimulation recorded in the dg, but not in ca3. |
2017-10-03 |
2023-08-13 |
rat |
| S Canetta, S Bolkan, N Padilla-Coreano, L J Song, R Sahn, N L Harrison, J A Gordon, A Brown, C Kellendon. Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons. Molecular psychiatry. vol 21. issue 7. 2017-09-25. PMID:26830140. |
abnormalities in prefrontal gamma aminobutyric acid (gaba)ergic transmission, particularly in fast-spiking interneurons that express parvalbumin (pv), are hypothesized to contribute to the pathophysiology of multiple psychiatric disorders, including schizophrenia, bipolar disorder, anxiety disorders and depression. |
2017-09-25 |
2023-08-13 |
mouse |
| Yanqing Wang, Brian D Burrel. Differences in chloride gradients allow for three distinct types of synaptic modulation by endocannabinoids. Journal of neurophysiology. vol 116. issue 2. 2017-09-07. PMID:27226449. |
in nmech neurons, which are depolarized by gaba due to an elevated cl(-) equilibrium potentials (ecl), endocannabinoid-mediated depression was prevented by blocking cl(-) import, indicating that this decrease in synaptic signaling was due to depression of excitatory gabaergic input (disexcitation). |
2017-09-07 |
2023-08-13 |
Not clear |
| Yanqing Wang, Brian D Burrel. Differences in chloride gradients allow for three distinct types of synaptic modulation by endocannabinoids. Journal of neurophysiology. vol 116. issue 2. 2017-09-07. PMID:27226449. |
npoly neurons are also depolarized by gaba, but endocannabinoids elicit depression in these synapses directly and were only weakly affected by disruption of cl(-) import. |
2017-09-07 |
2023-08-13 |
Not clear |
| B P Veronezi, A H Moffa, A F Carvalho, R Galhardoni, M Simis, I M Benseñor, P A Lotufo, R Machado-Vieira, Z J Daskalakis, A R Brunon. Evidence for increased motor cortical facilitation and decreased inhibition in atypical depression. Acta psychiatrica Scandinavica. vol 134. issue 2. 2017-07-18. PMID:27028276. |
our aim was to assess the atypical and melancholic depression subtypes regarding potential differences in gaba and glutamate receptor-mediated activity through established transcranial magnetic stimulation (tms) neurophysiological measures from the motor cortex. |
2017-07-18 |
2023-08-13 |
Not clear |
| Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Shunyan Mo, Hien P Nguyen, Abby Svenson, Nina Jaitly, Janet E Hall, Bruce A Barton, Anthony J Rothschild, Scott A Shaffe. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology. vol 70. 2017-06-13. PMID:27209438. |
nas and gaba are implicated in depression. |
2017-06-13 |
2023-08-13 |
human |
| Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Shunyan Mo, Hien P Nguyen, Abby Svenson, Nina Jaitly, Janet E Hall, Bruce A Barton, Anthony J Rothschild, Scott A Shaffe. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology. vol 70. 2017-06-13. PMID:27209438. |
we measured peripartum plasma nas and gaba in healthy comparison subjects (hcs) and those at-risk for postpartum depression (ar-ppd) due to current mild depressive or anxiety symptoms or a history of depression. |
2017-06-13 |
2023-08-13 |
human |
| Kristina M Deligiannidis, Aimee R Kroll-Desrosiers, Shunyan Mo, Hien P Nguyen, Abby Svenson, Nina Jaitly, Janet E Hall, Bruce A Barton, Anthony J Rothschild, Scott A Shaffe. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression. Psychoneuroendocrinology. vol 70. 2017-06-13. PMID:27209438. |
altered peripartum nas and gaba profiles in ar-ppd women suggest that their interaction may play an important role in the pathophysiology of peripartum depression and anxiety. |
2017-06-13 |
2023-08-13 |
human |
| Hong Hu, Xi Bai, Assar Ali Shah, Sifa Dai, Like Wang, Jinling Hua, Chuanyan Che, Shaojun He, Aiyou Wen, Jinpeng Jian. Interactive effects of glutamine and gamma-aminobutyric acid on growth performance and skeletal muscle amino acid metabolism of 22-42-day-old broilers exposed to hot environment. International journal of biometeorology. vol 60. issue 6. 2017-04-19. PMID:26493197. |
in conclusion, the present results indicated that the interactions of exogenous gln and gaba could offer a potential nutritional strategy to prevent hs-related depression in skeletal muscle gln and gaba metabolism of broilers. |
2017-04-19 |
2023-08-13 |
Not clear |
| Daniel J Norton, Ryan K McBain, Diego A Pizzagalli, Alice Cronin-Golomb, Yue Che. Dysregulation of visual motion inhibition in major depression. Psychiatry research. vol 240. 2017-02-21. PMID:27111216. |
individuals with depression show depleted concentrations of the inhibitory neurotransmitter gaba in occipital (visual) cortex, predicting weakened inhibition within their visual systems. |
2017-02-21 |
2023-08-13 |
human |
| Zhensong Wang, Aiying Zhang, Bin Zhao, Jie Gan, Guangbin Wang, Fei Gao, Bo Liu, Tao Gong, Wen Liu, Richard A E Edde. GABA+ levels in postmenopausal women with mild-to-moderate depression: A preliminary study. Medicine. vol 95. issue 39. 2017-02-15. PMID:27684829. |
this study aimed to explore in vivo gamma-aminobutyric acid (gaba) levels in the anterior cingulate cortex/medial prefrontal cortex (acc/mpfc) and posterior-cingulate cortex (pcc) of postmenopausal women with depression using magnetic resonance spectroscopy (h-mrs). |
2017-02-15 |
2023-08-13 |
Not clear |
| Chloé Thill, Laurence Di Constanzo, François Pessey, Philippe Aries, Étienne Montelescaut, Jeanne Sapin, Catherine Vaillant, Isabelle Drouillar. Self-induced drug intoxication in baclofen: of the calm hypotonic coma in the status epilepticus. Annales de biologie clinique. vol 74. issue 3. 2017-02-10. PMID:27237806. |
baclofen is an agonist of peripheral and central b gamma-aminobutyric acid receptors, whose activation causes a myorelaxation and a powerfull depression of the central nervous system. |
2017-02-10 |
2023-08-13 |
Not clear |
| J Roboon, S Nudmamud-Thanoi, S Thano. Recovery effect of pre-germinated brown rice on the alteration of sperm quality, testicular structure and androgen receptor expression in rat model of depression. Andrologia. vol 49. issue 1. 2017-02-09. PMID:27108772. |
male sprague dawley rats were divided into five groups including control (distilled water only), depression induced by forced swimming test (fst), fst + fluoxetine (antidepressant drug), fst + gaba (gamma-aminobutyric acid) (standard) and fst + pgbr. |
2017-02-09 |
2023-08-13 |
rat |
| Arianna Di Lorenzo, Seyed Fazel Nabavi, Antoni Sureda, Akbar Hajizadeh Moghaddam, Sedigheh Khanjani, Patrizia Arcidiaco, Seyed Mohammad Nabavi, Maria Dagli. Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression. Molecular nutrition & food research. vol 60. issue 3. 2016-12-13. PMID:26626862. |
antidepressive-like effects and antioxidant activity of green tea and gaba green tea in a mouse model of post-stroke depression. |
2016-12-13 |
2023-08-13 |
mouse |
| Arianna Di Lorenzo, Seyed Fazel Nabavi, Antoni Sureda, Akbar Hajizadeh Moghaddam, Sedigheh Khanjani, Patrizia Arcidiaco, Seyed Mohammad Nabavi, Maria Dagli. Antidepressive-like effects and antioxidant activity of green tea and GABA green tea in a mouse model of post-stroke depression. Molecular nutrition & food research. vol 60. issue 3. 2016-12-13. PMID:26626862. |
the aim of this study was to evaluate, in vivo, the protective activity of green tea (gt) and gaba green tea (ggt) against post-stroke depression (psd), a common consequence of stroke. |
2016-12-13 |
2023-08-13 |
mouse |
| Jan Kujala, Julien Jung, Sandrine Bouvard, Françoise Lecaignard, Amélie Lothe, Romain Bouet, Carolina Ciumas, Philippe Ryvlin, Karim Jerb. Gamma oscillations in V1 are correlated with GABA(A) receptor density: A multi-modal MEG and Flumazenil-PET study. Scientific reports. vol 5. 2016-09-26. PMID:26572733. |
these results bridge the gap with in-vitro and animal studies and may have future clinical implications given that altered gabaergic function, including dysregulation of gaba(a) receptors, has been related to psychiatric disorders including schizophrenia and depression. |
2016-09-26 |
2023-08-13 |
human |
| Carlos Alberto Yasin Wayhs, Helena Maria Tannhauser Barros, Carmen Regla Varga. GABAergic Modulation in Diabetic Encephalopathy-Related Depression. Current pharmaceutical design. vol 21. issue 34. 2016-08-15. PMID:26365139. |
furthermore, evidences from preclinical and clinical studies suggest that gaba plays a role both in the pathophysiology of the diabetic encephalopathy-related depression. |
2016-08-15 |
2023-08-13 |
human |
| Carlos Alberto Yasin Wayhs, Helena Maria Tannhauser Barros, Carmen Regla Varga. GABAergic Modulation in Diabetic Encephalopathy-Related Depression. Current pharmaceutical design. vol 21. issue 34. 2016-08-15. PMID:26365139. |
data presented from literature support the association between gaba and depressive- like behaviors in diabetic encephalopathy, being this neurotransmitter a potential target for the treatment of diabetes, depression and related comorbidities. |
2016-08-15 |
2023-08-13 |
human |