| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
[the interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. |
2016-05-26 |
2023-08-13 |
Not clear |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
gamma-aminobutyric acid (gaba) is the major inhibitory neurotransmitter of the central nervous system (cns) in mammalian, which involved in several mood disorders such as anxiety, depression and schizophrenia. |
2016-05-26 |
2023-08-13 |
Not clear |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
nowadays, there are growing evidences showed that the depression is concerned with a deficiency in brain gaba. |
2016-05-26 |
2023-08-13 |
Not clear |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
our aim is to discuss the relationship between depression and gaba by introducing the role of gaba receptors and the interaction between gaba and 5-hydroxytryptamine, dopamine and glutamic acid. |
2016-05-26 |
2023-08-13 |
Not clear |
| Po W Wang, Napapon Sailasuta, Rebecca A Chandler, Terence A Kette. Magnetic resonance spectroscopic measurement of cerebral gamma-aminobutyric acid concentrations in patients with bipolar disorders. Acta neuropsychiatrica. vol 18. issue 2. 2016-03-23. PMID:26989801. |
animal models of depression and psychopharmacological mechanisms of action suggest the importance of the gamma-amino butyric acid (gaba) system in the pathophysiology of mood disorders. |
2016-03-23 |
2023-08-13 |
Not clear |
| L Jiang, D Kang, J Kan. Potentiation of tonic GABAergic inhibition by activation of postsynaptic kainate receptors. Neuroscience. vol 298. 2016-03-21. PMID:25934031. |
presynaptic kainate-type glutamate ionotropic receptors (kars) that mediate either the depression or the facilitation of gaba release have been intensively studied. |
2016-03-21 |
2023-08-13 |
Not clear |
| Sara Faryadian, Afra Khosrav. Effects of prenatal exposure to different colors on offsprings mood. Iranian journal of basic medical sciences. vol 18. issue 11. 2016-03-07. PMID:26949495. |
there is much evidence indicating that depression is influenced by the levels of neurotransmitters such as dopamine, gaba and adrenaline. |
2016-03-07 |
2023-08-13 |
rat |
| Hongwei Wu, Peng Wang, Mengting Liu, Liying Tang, Jing Fang, Ye Zhao, Yi Zhang, Defeng Li, Haiyu Xu, Hongjun Yan. A 1H-NMR-Based Metabonomic Study on the Anti-Depressive Effect of the Total Alkaloid of Corydalis Rhizoma. Molecules (Basel, Switzerland). vol 20. issue 6. 2016-02-19. PMID:26035102. |
previous pharmacological studies showed that apart from analgesics, the alkaloids from yuanhu may be useful in the therapy of depression by acting on the gaba, dopamine and benzodiazepine receptors. |
2016-02-19 |
2023-08-13 |
rat |
| Kinga Sałat, Adrian Podkowa, Paula Kowalczyk, Katarzyna Kulig, Anna Dziubina, Barbara Filipek, Tadeusz Librowsk. Anticonvulsant active inhibitor of GABA transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression. Pharmacological reports : PR. vol 67. issue 3. 2016-02-12. PMID:25933955. |
anticonvulsant active inhibitor of gaba transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression. |
2016-02-12 |
2023-08-13 |
mouse |
| Katarzyna Młyniec, Magdalena Gaweł, Gabriel Nowa. Study of antidepressant drugs in GPR39 (zinc receptor⁻/⁻) knockout mice, showing no effect of conventional antidepressants, but effectiveness of NMDA antagonists. Behavioural brain research. vol 287. 2016-01-19. PMID:25827929. |
an antagonist of the glutamatergic nmda receptor - namely, zinc - plays a part in maintaining homeostasis between glutamate and gaba via the gpr39 receptor, which has been found to be involved in the pathophysiology of depression. |
2016-01-19 |
2023-08-13 |
mouse |
| Curtis Benson, Katherine Mifflin, Bradley Kerr, Sam J B Jesudasan, Serdar Dursun, Glen Bake. Biogenic Amines and the Amino Acids GABA and Glutamate: Relationships with Pain and Depression. Modern trends in pharmacopsychiatry. vol 30. 2016-01-07. PMID:26437459. |
biogenic amines and the amino acids gaba and glutamate: relationships with pain and depression. |
2016-01-07 |
2023-08-13 |
Not clear |
| Curtis Benson, Katherine Mifflin, Bradley Kerr, Sam J B Jesudasan, Serdar Dursun, Glen Bake. Biogenic Amines and the Amino Acids GABA and Glutamate: Relationships with Pain and Depression. Modern trends in pharmacopsychiatry. vol 30. 2016-01-07. PMID:26437459. |
it appears that numerous neurotransmitters and neuromodulators are involved, and this chapter focuses on the monoamine neurotransmitters noradrenaline, 5-hydroxytryptamine (5-ht, serotonin), and dopamine and the amino acid neurotransmitters gaba (γ-aminobutyric acid) and glutamate in chronic pain and depression. |
2016-01-07 |
2023-08-13 |
Not clear |
| Curtis Benson, Katherine Mifflin, Bradley Kerr, Sam J B Jesudasan, Serdar Dursun, Glen Bake. Biogenic Amines and the Amino Acids GABA and Glutamate: Relationships with Pain and Depression. Modern trends in pharmacopsychiatry. vol 30. 2016-01-07. PMID:26437459. |
similarly, preclinical and clinical studies on gabaergic and glutamatergic mechanisms as well as reports on the actions of neuroactive steroids suggest that gaba and glutamate play an important role in the etiology of pain and depression and may contribute to comorbidity. |
2016-01-07 |
2023-08-13 |
Not clear |
| Hang Xing, Kuo Zhang, Ruowen Zhang, Yuanyuan Zhang, Liqiang Gu, Huiyan Shi, Kaishun Bi, Xiaohui Che. Determination of depression biomarkers in rat plasma by liquid chromatography-mass spectrometry for the study of the antidepressant effect of Zhi-Zi-Hou-Po decoction on rat model of chronic unpredictable mild stress. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 988. 2015-12-15. PMID:25770791. |
the present study was designed to develop a liquid chromatography-mass spectrometry (lc-ms) method for simultaneous determination of depression biomarkers: tryptophan (trp), phenylalanine (phe), tyrosine (tyr), indole-3-acetic acid (iaa), hippuric acid (ha), phenaceturic acid (pa), creatinine (cr), glutamic acid (glu), succinic acid (sa) and γ-aminobutyric acid (gaba), as well as to study the antidepressant effect and potential mechanism of zzhpd based on holistic view of an organism. |
2015-12-15 |
2023-08-13 |
rat |
| Changjiu Zhao, Stephen C Gammi. Glutamate, GABA, and glutamine are synchronously upregulated in the mouse lateral septum during the postpartum period. Brain research. vol 1591. 2015-09-02. PMID:25451092. |
given that some mental health disorders, including depression and schizophrenia display dysregulated glutamate/gaba ratio, and there is increased vulnerability to mental disorders in mothers, it is possible that these postpartum disorders emerge when glutamate and gaba changes are not properly coordinated. |
2015-09-02 |
2023-08-13 |
mouse |
| T G Smart, A Constant. Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor. Proceedings of the Royal Society of London. Series B, Biological sciences. vol 227. issue 1247. 2015-07-14. PMID:26151987. |
the highly potent antagonist, picrotoxinin, produced a lateral shift and depression in the maximum of the gaba dose--conductance curve (designated as mixed antagonism); bicuculline, a weak antagonist, caused only a depression in the maximum with little or no lateral shift, whereas penicillin-g, an even weaker antagonist, produced a greater depression at the top of the dose--response curve. |
2015-07-14 |
2023-08-13 |
lobster |
| Agnieszka A Zurek, Jieying Yu, Dian-Shi Wang, Sean C Haffey, Erica M Bridgwater, Antonello Penna, Irene Lecker, Gang Lei, Tom Chang, Eric W R Salter, Beverley A Orse. Sustained increase in α5GABAA receptor function impairs memory after anesthesia. The Journal of clinical investigation. vol 124. issue 12. 2015-07-08. PMID:25365226. |
depression of brain function during anesthesia is attributed primarily to increased activity of γ-aminobutyric acid type a receptors (gaba(a)rs), and it is assumed that once the anesthetic drug is eliminated, the activity of gaba(a)rs rapidly returns to baseline and these receptors no longer impair memory. |
2015-07-08 |
2023-08-13 |
Not clear |
| Xingxiao Gao, Peng Sun, Mingqi Qiao, Sheng Wei, Ling Xue, Huiyun Zhan. Shu‑Yu capsule, a Traditional Chinese Medicine formulation, attenuates premenstrual syndrome depression induced by chronic stress constraint. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25270424. |
the present study aimed to investigate the therapeutic effect of the shu-yu capsule (syc), a traditional chinese medicine formulation, on premenstrual syndrome (pms) depression and the ratio of glutamate (glu) to γ-aminobutyric acid (gaba) in a rat model of pms depression. |
2015-06-19 |
2023-08-13 |
rat |
| J John Mann, Maria A Oquendo, Kalycia Trishana Watson, Maura Boldrini, Kevin M Malone, Steven P Ellis, Gregory Sullivan, Thomas B Cooper, Shan Xie, Dianne Currie. Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid. Depression and anxiety. vol 31. issue 10. 2015-06-17. PMID:24865448. |
anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid. |
2015-06-17 |
2023-08-13 |
Not clear |
| J John Mann, Maria A Oquendo, Kalycia Trishana Watson, Maura Boldrini, Kevin M Malone, Steven P Ellis, Gregory Sullivan, Thomas B Cooper, Shan Xie, Dianne Currie. Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid. Depression and anxiety. vol 31. issue 10. 2015-06-17. PMID:24865448. |
low gamma-aminobutyric acid (gaba) is implicated in both anxiety and depression pathophysiology. |
2015-06-17 |
2023-08-13 |
Not clear |