| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D I Kerr, J Ong, R Hughes, R H Prage. 3-amino-2-hydroxy-N-(4-nitrophenyl)-propanesulphonamide, a new class of GABAB receptor antagonist in central and peripheral preparations. European journal of pharmacology. vol 294. issue 1. 1997-02-12. PMID:8788452. |
racemic 3-amino-2-hydroxy-n-(4-nitrophenyl)-propanesulphonamide (ahpns), a sulphonamide analog of gaba, reversibly and competitively antagonised the concentration-dependent depression of cholinergic twitch contractions by baclofen, in the electrically stimulated guinea-pig isolated ileum, with a pa2 of 4.0 +/- 0.2. |
1997-02-12 |
2023-08-12 |
rat |
| R Lucchi, S Latini, A de Mendonça, A M Sebastião, J A Ribeir. Adenosine by activating A1 receptors prevents GABAA-mediated actions during hypoxia in the rat hippocampus. Brain research. vol 732. issue 1-2. 1997-02-06. PMID:8891295. |
the relative contribution of adenosine and gamma-aminobutyric acid (gaba) for the hypoxia-induced depression of field excitatory postsynaptic potentials in the ca1 area of rat hippocampal slices, was investigated. |
1997-02-06 |
2023-08-12 |
rat |
| S Delpierre, E Balzamo, C Pugnat, Y Jamme. Cardiorespiratory response to bicuculline during resistive loaded breathing in anesthetized rabbits. Neuroscience letters. vol 213. issue 1. 1996-12-19. PMID:8844701. |
accordingly, ventilatory depression should be minimized by gaba receptor blockade. |
1996-12-19 |
2023-08-12 |
Not clear |
| Z X Xi, T Akas. N-methyl-D-aspartate depresses GABAA receptor-mediated currents in neurons of bullfrog dorsal root ganglia. Neuroscience letters. vol 212. issue 1. 1996-12-04. PMID:8823752. |
dl-2-amino-5-phosphonovaleric acid (apv; 100 microm) antagonized the nmda-induced depression of the gaba current in a competitive manner. |
1996-12-04 |
2023-08-12 |
Not clear |
| Z X Xi, T Akas. N-methyl-D-aspartate depresses GABAA receptor-mediated currents in neurons of bullfrog dorsal root ganglia. Neuroscience letters. vol 212. issue 1. 1996-12-04. PMID:8823752. |
nmda induced no depression of the gaba current in a nominally ca(2+)-free solution containing 5 mm mg2+. |
1996-12-04 |
2023-08-12 |
Not clear |
| M RUSCA. INCREASE OF GAMMA-AMINOBUTYRIC ACID IN THE CEREBRAL CORTEX DURING ISCHAEMIA AND ITS RELATION TO EEG DEPRESSION. Physiologia bohemoslovenica. vol 12. 1996-12-01. PMID:14097877. |
increase of gamma-aminobutyric acid in the cerebral cortex during ischaemia and its relation to eeg depression. |
1996-12-01 |
2023-08-12 |
Not clear |
| T J Feuerstein, H Hüring, V van Velthoven, C H Lücking, G B Landwehrmeye. 5-HT1D-like receptors inhibit the release of endogenously formed [3H]GABA in human, but not in rabbit, neocortex. Neuroscience letters. vol 209. issue 3. 1996-11-08. PMID:8736648. |
the 5-ht1d receptor agonist sumatriptan depressed [3h]gaba release in human neocortex and the 5-ht1 receptor antagonist metitepin prevented this depression with potencies suggesting mediation by 5-ht1d-like receptors. |
1996-11-08 |
2023-08-12 |
human |
| A S Ramoa, M Su. Short-term synaptic plasticity in the visual cortex during development. Cerebral cortex (New York, N.Y. : 1991). vol 6. issue 4. 1996-10-24. PMID:8670689. |
consistent with a role of gagaergic inhibition, application of gaba receptor antagonists produced reversible blockade of paired-pulse depression. |
1996-10-24 |
2023-08-12 |
rat |
| S Grassi, G Della Torre, M Zampolini, V E Pettoross. Gaba mediated long-term depression (LTD) in the rat medial vestibular nuclei. Acta oto-laryngologica. Supplementum. vol 520 Pt 1. 1996-09-20. PMID:8749109. |
on the contrary, our findings suggest that the depression is due to an enhancement of the gaba inhibitory effect due to an hfs dependent increase in gabaergic interneuron activity, which resets vestibular neuron excitability at a lower level. |
1996-09-20 |
2023-08-12 |
rat |
| K Obrietan, A N van den Po. Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: a novel form of calcium long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627385. |
vigorous gaba-mediated ca2+ activity was found in young scn neurons that were maintained in vitro for 4-14 d. npy showed a dose-dependent rapid depression of the amplitude of ca2+ rises generated by gaba released from presynaptic scn axons. |
1996-06-21 |
2023-08-12 |
Not clear |
| K Obrietan, A N van den Po. Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: a novel form of calcium long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627385. |
this is the first example of such a cellular memory: that is, long-term ca2+ depression based on modulation of depolarizing gaba activity. |
1996-06-21 |
2023-08-12 |
Not clear |
| S Grassi, G Della Torre, G Capocchi, M Zampolini, V E Pettoross. The role of GABA in NMDA-dependent long term depression (LTD) of rat medial vestibular nuclei. Brain research. vol 699. issue 2. 1996-06-12. PMID:8616620. |
the involvement of gaba in mediating the depression was checked by applying the gabaa and gabab receptor antagonists, bicuculline and saclofen, before and after hfs. |
1996-06-12 |
2023-08-12 |
rat |
| S Grassi, G Della Torre, G Capocchi, M Zampolini, V E Pettoross. The role of GABA in NMDA-dependent long term depression (LTD) of rat medial vestibular nuclei. Brain research. vol 699. issue 2. 1996-06-12. PMID:8616620. |
according to our results, it is unlikely that the long lasting vestibular depression is the result of a homosynaptic ltd. on the contrary, our findings suggest that the depression is due to an enhancement of the gaba inhibitory effect, caused by an hfs dependent increase in gabaergic interneuron activity, which resets vestibular neuron excitability at a lower level. |
1996-06-12 |
2023-08-12 |
rat |
| R Khazipov, P Congar, Y Ben-Ar. Hippocampal CA1 lacunosum-moleculare interneurons: modulation of monosynaptic GABAergic IPSCs by presynaptic GABAB receptors. Journal of neurophysiology. vol 74. issue 5. 1996-04-03. PMID:8592201. |
potentiation of synaptic release of gaba, by increasing the extracellular ca2+ concentration to 4 mm and reducing the extracellular mg2+ concentration to 0.1 mm, enhanced the depression. |
1996-04-03 |
2023-08-12 |
rat |
| R Khazipov, P Congar, Y Ben-Ar. Hippocampal CA1 lacunosum-moleculare interneurons: modulation of monosynaptic GABAergic IPSCs by presynaptic GABAB receptors. Journal of neurophysiology. vol 74. issue 5. 1996-04-03. PMID:8592201. |
the strong correlation between the level of transmitter release and the degree of paired-pulse depression may have important physiological consequences, because in synapses with a high level of activity and a high level of gaba release, inhibition is powerful, but depression can develop more readily. |
1996-04-03 |
2023-08-12 |
rat |
| R Rimón, U Lepola, J Jolkkonen, T Halonen, P Riekkine. Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder. Biological psychiatry. vol 38. issue 11. 1996-03-21. PMID:8580226. |
low pretreatment level of csf gaba correlated significantly with poor therapeutic outcome, judged by the amount of anxiety and depression as well as by the frequency of panic attacks at the end of follow-up. |
1996-03-21 |
2023-08-12 |
Not clear |
| F Petty, M H Trivedi, M Fulton, A J Rus. Benzodiazepines as antidepressants: does GABA play a role in depression? Biological psychiatry. vol 38. issue 9. 1996-03-08. PMID:8573660. |
benzodiazepines as antidepressants: does gaba play a role in depression? |
1996-03-08 |
2023-08-12 |
Not clear |
| F Petty, M H Trivedi, M Fulton, A J Rus. Benzodiazepines as antidepressants: does GABA play a role in depression? Biological psychiatry. vol 38. issue 9. 1996-03-08. PMID:8573660. |
the antidepressant efficacy of benzodiazepines, which are gabaa receptor agonists, is consistent with the gaba theory of depression. |
1996-03-08 |
2023-08-12 |
Not clear |
| C Largo, P Cuevas, G G Somjen, R Martín del Río, O Herrera. The effect of depressing glial function in rat brain in situ on ion homeostasis, synaptic transmission, and neuron survival. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 3. 1996-02-28. PMID:8558250. |
after 4 hr, spreading depression (sd) waves that originated from the neocortex invaded hippocampal ca1, [k+]o increased to higher levels, pho became very acid, and there were steep increases in taurine, glutamate, and gaba levels. |
1996-02-28 |
2023-08-12 |
rat |
| F Pett. GABA and mood disorders: a brief review and hypothesis. Journal of affective disorders. vol 34. issue 4. 1996-02-20. PMID:8550953. |
animal models of depression show regional brain gaba deficits and gaba agonists have antidepressant activity in these models. |
1996-02-20 |
2023-08-12 |
Not clear |