| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amer Kamal, Geert M J Ramakers, Willem Hendrik Gispen, Geert Jan Biessels, Amer Al Ansar. Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms. Experimental brain research. vol 226. issue 1. 2013-12-27. PMID:23371746. |
in the electrophysiological experiments, the hippocampal slices were examined for paired-pulse facilitation (ppf), long-term potentiation (ltp), and depression expression. |
2013-12-27 |
2023-08-12 |
rat |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
xiangshao granule exerts antidepressive effects in a depression mouse model by ameliorating deficits in hippocampal bdnf and trkb. |
2013-12-24 |
2023-08-12 |
mouse |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
serum crh, cort, and acth levels were significantly increased in depression mice compared with control (p < 0.05) and the expression levels of hippocampal bdnf and trkb were reduced in the model group (p < 0.05). |
2013-12-24 |
2023-08-12 |
mouse |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
however, xiangshao granule treatment remarkably rescued the decrease in the body weight (p < 0.05), increased crossings in the open field test (p < 0.05), upregulated the expression of hippocampal bdnf and trkb expression, and reduced the serum crh, cort, and acth concentrations compared with the depression group (p < 0.05). |
2013-12-24 |
2023-08-12 |
mouse |
| Yi Chen, Jie Liu, Xiaoting Wu, Edouard Collins Nic. Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-12-24. PMID:24367385. |
collectively, these results demonstrated that xiangshao granule could effectively induce antidepressive effects in the depression mouse model by ameliorating the expression of hippocampal bdnf and trkb. |
2013-12-24 |
2023-08-12 |
mouse |
| Jie Gao, Chun-hong Song, Kai-yong X. [Study on estrogen receptors alpha and beta in the hippocampus of premenstrual syndrome model rats of gan-qi depression syndrome]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 31. issue 12. 2013-12-20. PMID:22384552. |
[study on estrogen receptors alpha and beta in the hippocampus of premenstrual syndrome model rats of gan-qi depression syndrome]. |
2013-12-20 |
2023-08-12 |
rat |
| Jie Gao, Chun-hong Song, Kai-yong X. [Study on estrogen receptors alpha and beta in the hippocampus of premenstrual syndrome model rats of gan-qi depression syndrome]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 31. issue 12. 2013-12-20. PMID:22384552. |
to study the distribution pattern, the protein expressions, and changes of functional activities of estrogen receptor (er) alpha and beta in the hippocampus of premenstrual syndrome (pms) rats of gan-qi depression syndrome (gds), and to find out corresponding effect targets of jingqianshu granule (jg), thus providing clues for exploring the pathogenesis of pms of gds and the mechanisms of jg. |
2013-12-20 |
2023-08-12 |
rat |
| Kette D R Valente, Geraldo Busatto Filh. Depression and temporal lobe epilepsy represent an epiphenomenon sharing similar neural networks: clinical and brain structural evidences. Arquivos de neuro-psiquiatria. vol 71. issue 3. 2013-12-17. PMID:23563720. |
interestingly, mesial temporal lobe epilepsy and depression share a similar neurocircuitry involving: temporal lobes with hippocampus, amygdala and entorhinal and neocortical cortex; the frontal lobes with cingulate gyrus; subcortical structures, such as basal ganglia and thalamus; and the connecting pathways. |
2013-12-17 |
2023-08-12 |
Not clear |
| Man Tang, Jieyu Lei, Xiao Sun, Guojun Liu, Shulei Zha. Stress-induced anhedonia correlates with lower hippocampal serotonin transporter protein expression. Brain research. vol 1513. 2013-12-16. PMID:23558306. |
the data indicate that down-regulation of hippocampal 5-htt protein expression is a signature change associated with anhedonia, a key endophenotype of clinical depression. |
2013-12-16 |
2023-08-12 |
mouse |
| I Mendez-David, R Hen, A M Gardier, D J Davi. Adult hippocampal neurogenesis: an actor in the antidepressant-like action. Annales pharmaceutiques francaises. vol 71. issue 3. 2013-12-16. PMID:23622692. |
the heterogeneous nature of depression suggests an involvement of multiple distinct brain regions including amygdala, prefrontal cortex and the hippocampus, which may be responsible for the diversity of the symptoms. |
2013-12-16 |
2023-08-12 |
Not clear |
| Javier de Diego-Adeliño, Maria J Portella, Beatriz Gómez-Ansón, Olga López-Moruelo, Maria Serra-Blasco, Yolanda Vives, Dolors Puigdemont, Rosario Pérez-Egea, Enric Álvarez, Víctor Pére. Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden. Journal of psychiatry & neuroscience : JPN. vol 38. issue 2. 2013-12-02. PMID:23425950. |
hippocampal abnormalities of glutamate/glutamine, n-acetylaspartate and choline in patients with depression are related to past illness burden. |
2013-12-02 |
2023-08-12 |
Not clear |
| Suguru Kawat. [Role of androgen in the elderly. Modulation of synaptic plasticity by brain-synthesized androgens]. Clinical calcium. vol 23. issue 8. 2013-11-18. PMID:23892214. |
after andropause or menopause, the levels of androgen and estrogen in the hippocampus may significantly decrease, inducing dementia, alzheimer's or depression. |
2013-11-18 |
2023-08-12 |
Not clear |
| Talvinder S Sihra, Antonio Rodríguez-Moren. Presynaptic kainate receptor-mediated bidirectional modulatory actions: mechanisms. Neurochemistry international. vol 62. issue 7. 2013-11-15. PMID:23538266. |
at hippocampal mossy fiber (mf)-ca3 synapses, kars have a biphasic effect on glutamate release, such that, depending on the extent of their activation, a facilitation or depression of glutamate release can be observed. |
2013-11-15 |
2023-08-12 |
Not clear |
| Konstantina Vassilopoulou, Matilda Papathanasiou, Ioannis Michopoulos, Fotini Boufidou, Panagiotis Oulis, Nikolaos Kelekis, Emmanouil Rizos, Chrysoula Nikolaou, Christos Pantelis, Dennis Velakoulis, Lefteris Lykoura. A magnetic resonance imaging study of hippocampal, amygdala and subgenual prefrontal cortex volumes in major depression subtypes: melancholic versus psychotic depression. Journal of affective disorders. vol 146. issue 2. 2013-11-13. PMID:23021193. |
a magnetic resonance imaging study of hippocampal, amygdala and subgenual prefrontal cortex volumes in major depression subtypes: melancholic versus psychotic depression. |
2013-11-13 |
2023-08-12 |
Not clear |
| Jennifer G Bray, Kenneth C Reyes, Amanda J Roberts, Richard M Ransohoff, Donna L Gruo. Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Neuropharmacology. vol 67. 2013-11-04. PMID:23164616. |
however, long-term potentiation (ltp), a cellular mechanism thought to underlie learning and memory, in the ccl2-transgenic hippocampus was resistant to the ethanol-induced depression of ltp observed in the non-transgenic hippocampus. |
2013-11-04 |
2023-08-12 |
mouse |
| Teresa F Burke, Tushar Advani, Megumi Adachi, Lisa M Monteggia, Julie G Hensle. Sensitivity of hippocampal 5-HT1A receptors to mild stress in BDNF-deficient mice. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22575584. |
decreased brain-derived neurotrophic factor (bdnf) expression and/or function, particularly in hippocampus, are implicated in the pathophysiology of stress-related disorders such as major depression. |
2013-10-31 |
2023-08-12 |
mouse |
| J Olazarán, R Trincado, F Bermejo-Parej. Cumulative effect of depression on dementia risk. International journal of Alzheimer's disease. vol 2013. 2013-10-25. PMID:24159419. |
multiple mechanisms, including toxic effect of depression on hippocampal neurons, plausibly explain these associations. |
2013-10-25 |
2023-08-12 |
human |
| Daniela Schulz, David Smith, Mei Yu, Hedok Lee, Fritz A Hen. Selective breeding for helplessness in rats alters the metabolic profile of the hippocampus and frontal cortex: a 1H-MRS study at 9.4 T. The international journal of neuropsychopharmacology. vol 16. issue 1. 2013-10-17. PMID:22272798. |
selective breeding for helplessness in rats alters the metabolic profile of the hippocampus and frontal cortex: a 1h-mrs study at 9.4 t. in humans metabolic changes, particularly in frontal areas of the brain, accompany depressive disorders, but few studies were conducted in animal models of depression. |
2013-10-17 |
2023-08-12 |
rat |
| Min-Jeong Kim, Sang Won Seo, Geon Ha Kim, Sung Tae Kim, Jong-Min Lee, Anqi Qiu, Duk L N. Less depressive symptoms are associated with smaller hippocampus in subjective memory impairment. Archives of gerontology and geriatrics. vol 57. issue 1. 2013-10-17. PMID:23462582. |
when multiple regression analysis was conducted in all subjects, neither hippocampal nor amygdalar volume showed significant interaction effect between group and geriatric depression scale (gds). |
2013-10-17 |
2023-08-12 |
human |
| Sylvie Burnouf, Alberto Martire, Maxime Derisbourg, Cyril Laurent, Karim Belarbi, Antoine Leboucher, Francisco J Fernandez-Gomez, Laetitia Troquier, Sabiha Eddarkaoui, Marie-Eve Grosjean, Dominique Demeyer, Anne Muhr-Tailleux, Alain Buisson, Nicolas Sergeant, Malika Hamdane, Sandrine Humez, Patrizia Popoli, Luc Buée, David Blu. NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model. Aging cell. vol 12. issue 1. 2013-09-30. PMID:23082852. |
indeed, we observed a significant reduction of nmda-induced field excitatory postsynaptic potential depression in the hippocampus of tau mice together with a reduced phosphorylation of nr2b at the y1472, known to be critical for nmdar function. |
2013-09-30 |
2023-08-12 |
mouse |