| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Níall Lally, Allison C Nugent, David A Luckenbaugh, Mark J Niciu, Jonathan P Roiser, Carlos A Zarat. Neural correlates of change in major depressive disorder anhedonia following open-label ketamine. Journal of psychopharmacology (Oxford, England). vol 29. issue 5. 2016-02-23. PMID:25691504. |
the tentative relationship between change in anhedonia and glucose metabolism remained significant in dacc and ofc, and at trend level in the hippocampus, a result not anticipated, when controlling for change in total depression score. |
2016-02-23 |
2023-08-13 |
human |
| Jennifer L Phillips, Lisa A Batten, Philippe Tremblay, Fahad Aldosary, Pierre Blie. A Prospective, Longitudinal Study of the Effect of Remission on Cortical Thickness and Hippocampal Volume in Patients with Treatment-Resistant Depression. The international journal of neuropsychopharmacology. vol 18. issue 8. 2016-02-23. PMID:25829180. |
a prospective, longitudinal study of the effect of remission on cortical thickness and hippocampal volume in patients with treatment-resistant depression. |
2016-02-23 |
2023-08-13 |
Not clear |
| Michaela Pavlovicova, Lubica Lacinova, Eliyahu Dremenco. Cellular and molecular mechanisms underlying the treatment of depression: focusing on hippocampal G-protein-coupled receptors and voltage-dependent calcium channels. General physiology and biophysics. vol 34. issue 4. 2016-02-23. PMID:25926550. |
cellular and molecular mechanisms underlying the treatment of depression: focusing on hippocampal g-protein-coupled receptors and voltage-dependent calcium channels. |
2016-02-23 |
2023-08-13 |
Not clear |
| M Elbejjani, R Fuhrer, M Abrahamowicz, B Mazoyer, F Crivello, C Tzourio, C Dufoui. Depression, depressive symptoms, and rate of hippocampal atrophy in a longitudinal cohort of older men and women. Psychological medicine. vol 45. issue 9. 2016-02-17. PMID:25896060. |
several studies have reported smaller hippocampal volume (hcv) in depression patients; however, the temporality of the association remains unknown. |
2016-02-17 |
2023-08-13 |
Not clear |
| Deng-Xin Zhang, Shan Jiang, Li-Na Yu, Feng-Jiang Zhang, Qing Zhuang, Min Ya. The effect of sevoflurane on the cognitive function of rats and its association with the inhibition of synaptic transmission. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885010. |
to observe the effects of different concentrations of sevoflurane on synaptotagmin 1 (syt1) expression, synaptic long term depression (ltd), and paired pulse depression (ppd) in the rat hippocampus as well as to investigate the association between these effects and the cognitive function of rats. |
2016-02-17 |
2023-08-13 |
rat |
| Roberta Imperatore, Giovanna Morello, Livio Luongo, Ulrike Taschler, Rosaria Romano, Danilo De Gregorio, Carmela Belardo, Sabatino Maione, Vincenzo Di Marzo, Luigia Cristin. Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB₁R signaling and anxiety-like behavior. Journal of neurochemistry. vol 135. issue 4. 2016-02-16. PMID:26223500. |
in this study, the authors provide evidence that congenitally enhanced endocannabinoid levels in the neuronal circuits underlying anxiety-like behavioral states (mainly medial prefrontal cortex, amygdala and hippocampus) lead to cb1r desenistization and anxiety and depression. |
2016-02-16 |
2023-08-13 |
mouse |
| Robert Blum, Klaus-Peter Lesc. Parkinson's disease, anxious depression and serotonin--zooming in on hippocampal neurogenesis. Journal of neurochemistry. vol 135. issue 3. 2016-02-11. PMID:26382574. |
parkinson's disease, anxious depression and serotonin--zooming in on hippocampal neurogenesis. |
2016-02-11 |
2023-08-13 |
Not clear |
| Run-hui Shao, Shu-ying Jin, Jun Lu, Li Hu, Ya T. [Effect of Acupuncture Intervention on Expression of NF-κB Signal Pathway in the Hippocampus of Chronic Stress-induced Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 40. issue 5. 2016-02-09. PMID:26669192. |
[effect of acupuncture intervention on expression of nf-κb signal pathway in the hippocampus of chronic stress-induced depression rats]. |
2016-02-09 |
2023-08-13 |
rat |
| Run-hui Shao, Shu-ying Jin, Jun Lu, Li Hu, Ya T. [Effect of Acupuncture Intervention on Expression of NF-κB Signal Pathway in the Hippocampus of Chronic Stress-induced Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 40. issue 5. 2016-02-09. PMID:26669192. |
to observe the influence of acupuncture intervention on the expression of pivotal pro-inflammatory molecules nuclear factor-κb (nf-κb), cyclooxygenase-2 (cox-2), and prostaglandin e2 (pge2) of nf-κb inflammatory signal pathway in the hippocampus of depression rats, so as to explore its mechanism underlying improvement of depression. |
2016-02-09 |
2023-08-13 |
rat |
| Ya Bin Wei, Lena Backlund, Gregers Wegener, Aleksander A Mathé, Catharina Lavebrat. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. The international journal of neuropsychopharmacology. vol 18. issue 7. 2016-02-05. PMID:25618407. |
telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. |
2016-02-05 |
2023-08-13 |
human |
| Y R Sun, X Y Wang, S S Li, H Y Dong, X J Zhan. β-asarone from Acorus gramineus alleviates depression by modulating MKP-1. Genetics and molecular research : GMR. vol 14. issue 2. 2016-02-05. PMID:25966222. |
in this study, we investigated the antidepressant effects of hippocampal neuron administration of β-asarone, a selective mitogen-activated protein kinase phosphatase-1 inhibitor, in a rat model of depression. |
2016-02-05 |
2023-08-13 |
rat |
| Guo-Jiang Peng, Bi-Yun Shi, Jun-Sheng Tian, Shan Gao, Xue-Mei Qi. [1H NMR based metabonomics study on the antidepressant effect of genipin in rat hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 49. issue 2. 2016-02-02. PMID:24761611. |
the purpose of this study is to explore depression metabolic markers in rat hippocampus and to investigate the anti-depressant effect of genipin and its mechanisms using nuclear magnetic resonance (nmr) metabonomics. |
2016-02-02 |
2023-08-13 |
rat |
| Daniel Rial, Cristina Lemos, Helena Pinheiro, Joana M Duarte, Francisco Q Gonçalves, Joana I Real, Rui D Prediger, Nélio Gonçalves, Catarina A Gomes, Paula M Canas, Paula Agostinho, Rodrigo A Cunh. Depression as a Glial-Based Synaptic Dysfunction. Frontiers in cellular neuroscience. vol 9. 2016-02-02. PMID:26834566. |
recent studies combining pharmacological, behavioral, electrophysiological and molecular approaches indicate that depression results from maladaptive neuroplastic processes occurring in defined frontolimbic circuits responsible for emotional processing such as the prefrontal cortex, hippocampus, amygdala and ventral striatum. |
2016-02-02 |
2023-08-13 |
Not clear |
| Jonathan Savitz, Robert Dantzer, Brent E Wurfel, Teresa A Victor, Bart N Ford, Jerzy Bodurka, P S F Bellgowan, T Kent Teague, Wayne C Drevet. Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder. Psychoneuroendocrinology. vol 52. 2016-01-29. PMID:25486577. |
the results raise the possibility that bd-associated abnormalities in kynurenine metabolism may impact the structure of the hippocampus and amygdala, highlighting a pathway through which inflammation may exert neuropathological effects in the context of depression. |
2016-01-29 |
2023-08-13 |
human |
| Petr Bednařík, Amir Moheet, Dinesh K Deelchand, Uzay E Emir, Lynn E Eberly, Martin Bareš, Elizabeth R Seaquist, Gülin Ö. Feasibility and reproducibility of neurochemical profile quantification in the human hippocampus at 3 T. NMR in biomedicine. vol 28. issue 6. 2016-01-29. PMID:25904240. |
hippocampal dysfunction is known to be associated with several neurological and neuropsychiatric disorders such as alzheimer's disease, epilepsy, schizophrenia and depression; therefore, there has been significant clinical interest in studying hippocampal neurochemistry. |
2016-01-29 |
2023-08-13 |
human |
| B Liu, C Xu, X Wu, F Liu, Y Du, J Sun, J Tao, J Don. Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation. Neuroscience. vol 294. 2016-01-28. PMID:25791226. |
icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation. |
2016-01-28 |
2023-08-13 |
mouse |
| Federica Ferrari, Antonella Gorini, Roberto Federico Vill. Functional proteomics of synaptic plasma membrane ATP-ases of rat hippocampus: effect of l-acetylcarnitine and relationships with Dementia and Depression pathophysiology. European journal of pharmacology. vol 756. 2016-01-28. PMID:25797282. |
functional proteomics of synaptic plasma membrane atp-ases of rat hippocampus: effect of l-acetylcarnitine and relationships with dementia and depression pathophysiology. |
2016-01-28 |
2023-08-13 |
rat |
| Federica Ferrari, Antonella Gorini, Roberto Federico Vill. Functional proteomics of synaptic plasma membrane ATP-ases of rat hippocampus: effect of l-acetylcarnitine and relationships with Dementia and Depression pathophysiology. European journal of pharmacology. vol 756. 2016-01-28. PMID:25797282. |
the effects of the drug on the maximum rate (vmax) of enzymatic activities related to hippocampal synaptic energy utilization were evaluated, in the perspective of its employment for dementias and depression therapy. |
2016-01-28 |
2023-08-13 |
rat |
| Oliver Kaut, Ina Schmitt, Andrea Hofmann, Per Hoffmann, Thomas E Schlaepfer, Ullrich Wüllner, René Hurleman. Aberrant NMDA receptor DNA methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression. European archives of psychiatry and clinical neuroscience. vol 265. issue 4. 2016-01-26. PMID:25571874. |
aberrant nmda receptor dna methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression. |
2016-01-26 |
2023-08-13 |
human |
| Erin Y Fenton, Neil M Fournier, April L Lussier, Raquel Romay-Tallon, Hector J Caruncho, Lisa E Kalynchu. Imipramine protects against the deleterious effects of chronic corticosterone on depression-like behavior, hippocampal reelin expression, and neuronal maturation. Progress in neuro-psychopharmacology & biological psychiatry. vol 60. 2016-01-22. PMID:25681757. |
we have hypothesized that a downregulation of reelin and deficient maturation of adult-born hippocampal neurons are important factors in the pathogenesis of depression. |
2016-01-22 |
2023-08-13 |
mouse |