| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela L Lee, William O Ogle, Robert M Sapolsk. Stress and depression: possible links to neuron death in the hippocampus. Bipolar disorders. vol 4. issue 2. 2002-11-07. PMID:12071509. |
stress and depression: possible links to neuron death in the hippocampus. |
2002-11-07 |
2023-08-12 |
Not clear |
| Angela L Lee, William O Ogle, Robert M Sapolsk. Stress and depression: possible links to neuron death in the hippocampus. Bipolar disorders. vol 4. issue 2. 2002-11-07. PMID:12071509. |
recent intriguing reports have shown an association between major depression and selective and persistent loss of hippocampal volume, prompting considerable speculation as to its underlying causes. |
2002-11-07 |
2023-08-12 |
Not clear |
| Angela L Lee, William O Ogle, Robert M Sapolsk. Stress and depression: possible links to neuron death in the hippocampus. Bipolar disorders. vol 4. issue 2. 2002-11-07. PMID:12071509. |
the subtypes of depression associated with hippocampal atrophy typically involve significant hypersecretion of glucocorticoids, the adrenal steroids secreted during stress. |
2002-11-07 |
2023-08-12 |
Not clear |
| Abdulmonem Al-Hayani, Stephen N Davie. Effect of cannabinoids on synaptic transmission in the rat hippocampal slice is temperature-dependent. European journal of pharmacology. vol 442. issue 1-2. 2002-10-08. PMID:12020681. |
we have previously reported that the synthetic cannabinoid r-(+)-[2,3-dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazin-yl]-(1-naphthalenyl)methanone mesylate (win55,212-2) causes a selective inhibition of paired pulse depression of population spikes recorded from the ca1 region of rat hippocampal slices maintained at 28-30 degrees c. we now show that this effect is highly temperature-dependent and that win55,212-2 actually increases paired pulse depression of population spikes recorded from slices maintained at 35 degrees c. this temperature dependence was found to correlate with the effects of the known gamma-amino butyric acid (gaba)-uptake inhibitors, nipecotic acid and guvacine, which were without effect at 28-30 degrees c, but increased paired pulse depression at 35 degrees c. the results show that the effects of cannabinoids on synaptic transmission in the hippocampal slice are highly temperature-dependent and it is suggested that this is due to the presence of increased gaba uptake at higher temperatures. |
2002-10-08 |
2023-08-12 |
rat |
| Frédéric Robert, Lionel Bert, Luc Stoppin. Blockade of NMDA-receptors or calcium-channels attenuates the ischaemia-evoked efflux of glutamate and phosphoethanolamine and depression of neuronal activity in rat organotypic hippocampal slice cultures. Comptes rendus biologies. vol 325. issue 4. 2002-10-08. PMID:12161929. |
blockade of nmda-receptors or calcium-channels attenuates the ischaemia-evoked efflux of glutamate and phosphoethanolamine and depression of neuronal activity in rat organotypic hippocampal slice cultures. |
2002-10-08 |
2023-08-12 |
rat |
| I C Grunwald, M Korte, D Wolfer, G A Wilkinson, K Unsicker, H P Lipp, T Bonhoeffer, R Klei. Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity. Neuron. vol 32. issue 6. 2002-10-01. PMID:11754835. |
in ephb2(-/-) hippocampal slices, protein synthesis-dependent long-term potentiation (ltp) was impaired, and two forms of synaptic depression were completely extinguished. |
2002-10-01 |
2023-08-12 |
mouse |
| F Peña, J Bargas, R Tapi. Paired pulse facilitation is turned into paired pulse depression in hippocampal slices after epilepsy induced by 4-aminopyridine in vivo. Neuropharmacology. vol 42. issue 6. 2002-09-25. PMID:12015207. |
paired pulse facilitation is turned into paired pulse depression in hippocampal slices after epilepsy induced by 4-aminopyridine in vivo. |
2002-09-25 |
2023-08-12 |
rat |
| C A Stewart, I C Rei. Antidepressant mechanisms: functional and molecular correlates of excitatory amino acid neurotransmission. Molecular psychiatry. vol 7 Suppl 1. 2002-09-04. PMID:11986991. |
there is clinical evidence that patients with chronic depression have structural brain abnormalities, including hippocampal atrophy, and a preliminary study has shown that an n-methyl-d-aspartate receptor antagonist may have antidepressant efficacy. |
2002-09-04 |
2023-08-12 |
Not clear |
| Guido C Faas, Hita Adwanikar, Robert W Gereau, Peter Sagga. Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 16. 2002-09-04. PMID:12177186. |
activation of group i metabotropic glutamate receptors (mglurs) can induce acute depression of excitatory synaptic transmission and long-term depression (ltd) in area ca1 of the rat hippocampus. |
2002-09-04 |
2023-08-12 |
rat |
| Vivien Chevaleyre, Pablo E Castill. Assessing the role of Ih channels in synaptic transmission and mossy fiber LTP. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 14. 2002-08-08. PMID:12093909. |
furthermore, ih does not significantly modify basal excitatory synaptic transmission in the hippocampus, whereas the organic ih blockers zd7288 and dk-ah 269 induce a large ih-independent depression of synaptic transmission. |
2002-08-08 |
2023-08-12 |
Not clear |
| J Benninghoff, A Schmitt, R Mössner, K-P Lesc. When cells become depressed: focus on neural stem cells in novel treatment strategies against depression. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111481. |
while elucidation of factors that lead to depression is still in its infancy, biochemical malfunctions appear to have well defined morphological correlations, especially in the hippocampus. |
2002-08-06 |
2023-08-12 |
Not clear |
| Ming-Hong Hsieh, Douglas R McQuoid, Robert M Levy, Martha E Payne, James R MacFall, David C Steffen. Hippocampal volume and antidepressant response in geriatric depression. International journal of geriatric psychiatry. vol 17. issue 6. 2002-07-30. PMID:12112175. |
hippocampal volume and antidepressant response in geriatric depression. |
2002-07-30 |
2023-08-12 |
Not clear |
| Ming-Hong Hsieh, Douglas R McQuoid, Robert M Levy, Martha E Payne, James R MacFall, David C Steffen. Hippocampal volume and antidepressant response in geriatric depression. International journal of geriatric psychiatry. vol 17. issue 6. 2002-07-30. PMID:12112175. |
while most imaging studies have focused on cerebrovascular disease, evidence is growing that the hippocampus may play a role in depression, particularly geriatric depression. |
2002-07-30 |
2023-08-12 |
Not clear |
| F Wendling, F Bartolomei, J J Bellanger, P Chauve. Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition. The European journal of neuroscience. vol 15. issue 9. 2002-07-26. PMID:12028360. |
it starts with recent hypotheses about: (i) the behaviour of inhibitory interneurons in hippocampal or neocortical networks in the generation of gamma frequency oscillations; (ii) the nonuniform alteration of gabaergic inhibition in experimental epilepsy (reduced dendritic inhibition and increased somatic inhibition); and (iii) the possible depression of gaba(a,fast) circuit activity by gaba(a,slow) inhibitory postsynaptic currents. |
2002-07-26 |
2023-08-12 |
human |
| Thomas Frodl, Eva M Meisenzahl, Thomas Zetzsche, Christine Born, Constanze Groll, Markus Jäger, Gerda Leinsinger, Ronald Bottlender, Klaus Hahn, Hans-Jürgen Mölle. Hippocampal changes in patients with a first episode of major depression. The American journal of psychiatry. vol 159. issue 7. 2002-07-25. PMID:12091188. |
hippocampal changes in patients with a first episode of major depression. |
2002-07-25 |
2023-08-12 |
human |
| Thomas Frodl, Eva M Meisenzahl, Thomas Zetzsche, Christine Born, Constanze Groll, Markus Jäger, Gerda Leinsinger, Ronald Bottlender, Klaus Hahn, Hans-Jürgen Mölle. Hippocampal changes in patients with a first episode of major depression. The American journal of psychiatry. vol 159. issue 7. 2002-07-25. PMID:12091188. |
in the present study, differences in volumes of hippocampal gray and white matter between patients with a first episode of major depression and healthy comparison subjects were examined. |
2002-07-25 |
2023-08-12 |
human |
| J M Wierońska, P Brański, B Szewczyk, A Pałucha, M Papp, P Gruca, E Moryl, A Pil. Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. Polish journal of pharmacology. vol 53. issue 6. 2002-07-19. PMID:11985342. |
changes in the expression of metabotropic glutamate receptor 5 (mglur5) in the rat hippocampus in an animal model of depression. |
2002-07-19 |
2023-08-12 |
rat |
| Gerd Kemperman. Regulation of adult hippocampal neurogenesis - implications for novel theories of major depression. Bipolar disorders. vol 4. issue 1. 2002-07-12. PMID:12047492. |
regulation of adult hippocampal neurogenesis - implications for novel theories of major depression. |
2002-07-12 |
2023-08-12 |
Not clear |
| Gerd Kemperman. Regulation of adult hippocampal neurogenesis - implications for novel theories of major depression. Bipolar disorders. vol 4. issue 1. 2002-07-12. PMID:12047492. |
in this review, the potential role of adult hippocampal neurogenesis and of neuronal stem or progenitor cells in depression is discussed with regard to those aspects that are brought up by recent research on how adult hippocampal neurogenesis is regulated. |
2002-07-12 |
2023-08-12 |
Not clear |
| Cheryl A Frye, Alicia A Wal. Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats. Hormones and behavior. vol 41. issue 3. 2002-07-03. PMID:11971664. |
the purpose of these experiments was to test the hypothesis that attenuating the endogenous increase of the 5alpha-reduced progesterone metabolite 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-thp) in the hippocampus will alter anxiety and depression behavior of proestrous rats. |
2002-07-03 |
2023-08-12 |
rat |