| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Frodl, Eva M Meisenzahl, Thomas Zetzsche, Tom Höhne, Sandra Banac, Constanze Schorr, Markus Jäger, Gerda Leinsinger, Ronald Bottlender, Maximilian Reiser, Hans-Jürgen Mölle. Hippocampal and amygdala changes in patients with major depressive disorder and healthy controls during a 1-year follow-up. The Journal of clinical psychiatry. vol 65. issue 4. 2004-05-25. PMID:15119911. |
although the hippocampus has been found to be smaller in patients with depression, prospective longitudinal in vivo studies are necessary to investigate whether depression can result in a further diminution of hippocampal volumes or whether a smaller hippocampal volume predisposes an individual to the development of depression. |
2004-05-25 |
2023-08-12 |
Not clear |
| Rui Li, Mikhail Dozmorov, Fredrik Hellberg, Ye Tian, Barbro Jilderos, Holger Wigströ. Characterization of NMDA induced depression in rat hippocampus: involvement of AMPA and NMDA receptors. Neuroscience letters. vol 357. issue 2. 2004-05-13. PMID:15036581. |
characterization of nmda induced depression in rat hippocampus: involvement of ampa and nmda receptors. |
2004-05-13 |
2023-08-12 |
rat |
| Christopher M Bocchiaro, Jack L Feldma. Synaptic activity-independent persistent plasticity in endogenously active mammalian motoneurons. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 12. 2004-05-10. PMID:15024116. |
potentiation and depression of glutamate receptor function in hippocampal, cerebellar, and cortical neurons are examples of persistent changes in synaptic function that underlie important behavioral adaptations such as learning and memory. |
2004-05-10 |
2023-08-12 |
Not clear |
| Olena Bukalo, Nikolas Fentrop, Alan Y W Lee, Benedikt Salmen, Janice W S Law, Carsten T Wotjak, Michaela Schweizer, Alexander Dityatev, Melitta Schachne. Conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the CA1 subfield of mouse hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 7. 2004-05-04. PMID:14973228. |
conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the ca1 subfield of mouse hippocampus. |
2004-05-04 |
2023-08-12 |
mouse |
| E Sherwood Brown, Femina P Varghese, Bruce S McEwe. Association of depression with medical illness: does cortisol play a role? Biological psychiatry. vol 55. issue 1. 2004-04-28. PMID:14706419. |
much interest has focused on the possible effects of depression on the hippocampus; however, an emerging body of evidence suggests an association between depression and non-central nervous system illnesses. |
2004-04-28 |
2023-08-12 |
Not clear |
| E Sherwood Brown, Femina P Varghese, Bruce S McEwe. Association of depression with medical illness: does cortisol play a role? Biological psychiatry. vol 55. issue 1. 2004-04-28. PMID:14706419. |
from searches of the medline, psychinfo, and current contents databases, and other sources, articles were found specifically related to depression and physical changes or medical conditions associated with corticosteroid excess in patients with cushing's disease, including cognitive impairment, hippocampal atrophy, increased waist-to-hip ratio, bone loss, hypertension, diabetes, peptic ulcers, and hyperlipidemia. |
2004-04-28 |
2023-08-12 |
Not clear |
| Edyta Jurkowlaniec, Juliusz Tokarski, Weronika Trojnia. Effect of unilateral ibotenate lesions of the ventral tegmental area on cortical and hippocampal EEG in freely behaving rats. Acta neurobiologiae experimentalis. vol 63. issue 4. 2004-04-19. PMID:15053260. |
in the hippocampus the depression was slightly more intense ipsilaterally, also involving all the frequency bands although to different degrees. |
2004-04-19 |
2023-08-12 |
rat |
| Cary L Scheiderer, Lynn E Dobrunz, Lori L McMaho. Novel form of long-term synaptic depression in rat hippocampus induced by activation of alpha 1 adrenergic receptors. Journal of neurophysiology. vol 91. issue 2. 2004-03-31. PMID:14573563. |
novel form of long-term synaptic depression in rat hippocampus induced by activation of alpha 1 adrenergic receptors. |
2004-03-31 |
2023-08-12 |
rat |
| Gong Chen, Nobutoshi C Harata, Richard W Tsie. Paired-pulse depression of unitary quantal amplitude at single hippocampal synapses. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 4. 2004-03-30. PMID:14722357. |
paired-pulse depression of unitary quantal amplitude at single hippocampal synapses. |
2004-03-30 |
2023-08-12 |
human |
| Marieke C Wichers, Michael Mae. The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression. Journal of psychiatry & neuroscience : JPN. vol 29. issue 1. 2004-03-25. PMID:14719046. |
both ros overproduction and hippocampal atrophy caused by nmda overstimulation have been associated with depression. |
2004-03-25 |
2023-08-12 |
Not clear |
| Cyril Rocher, Michael Spedding, Carmen Munoz, Thérèse M Ja. Acute stress-induced changes in hippocampal/prefrontal circuits in rats: effects of antidepressants. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 2. 2004-03-19. PMID:14704220. |
acute stress inhibits long-term potentiation (ltp) at synapses from the hippocampus to prefrontal cortex in the rat, a model of the dysfunction in the anterior cingulate/orbitofrontal cortices which has been observed in human depression. |
2004-03-19 |
2023-08-12 |
human |
| Hrvoje Hećimović, Jennifer D Goldstein, Yvette I Sheline, Frank G Gillia. Mechanisms of depression in epilepsy from a clinical perspective. Epilepsy & behavior : E&B. vol 4 Suppl 3. 2004-03-11. PMID:14592637. |
the brain regions commonly involved in various types of epilepsies, such as the hippocampus and amygdala in temporal lobe epilepsy and subcortical nuclei in idiopathic generalized epilepsies, are important components of current models of depression. |
2004-03-11 |
2023-08-12 |
Not clear |
| Thomas Frodl, Eva M Meisenzahl, Peter Zill, Thomas Baghai, Dan Rujescu, Gerda Leinsinger, Ronald Bottlender, Cornelius Schüle, Peter Zwanzger, Rolf R Engel, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Mölle. Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. Archives of general psychiatry. vol 61. issue 2. 2004-02-24. PMID:14757594. |
reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. |
2004-02-24 |
2023-08-12 |
Not clear |
| Jingshan Chen, Samuel S Newton, Ling Zeng, David H Adams, Anthoni L Dow, Torsten M Madsen, Eric J Nestler, Ronald S Duma. Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB transgenic mice and by electroconvulsive seizures. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 1. 2004-02-17. PMID:14532910. |
analysis of the c/ebpbeta expression in the hippocampus of rats treated with ecs revealed that the c/ebpbeta mrna was also downregulated by chronic, but not acute ecs administration, the most effective treatment for depression. |
2004-02-17 |
2023-08-12 |
mouse |
| Marco Mula, Michael R Trimble, Josemir W A S Sande. The role of hippocampal sclerosis in topiramate-related depression and cognitive deficits in people with epilepsy. Epilepsia. vol 44. issue 12. 2004-02-17. PMID:14636330. |
the role of hippocampal sclerosis in topiramate-related depression and cognitive deficits in people with epilepsy. |
2004-02-17 |
2023-08-12 |
Not clear |
| Yo Otsu, Vahid Shahrezaei, Bo Li, Lynn A Raymond, Kerry R Delaney, Timothy H Murph. Competition between phasic and asynchronous release for recovered synaptic vesicles at developing hippocampal autaptic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 2. 2004-02-11. PMID:14724240. |
developing hippocampal neurons in microisland culture undergo rapid and extensive transmitter release-dependent depression of evoked (phasic) excitatory synaptic activity in response to 1 sec trains of 20 hz stimulation. |
2004-02-11 |
2023-08-12 |
Not clear |
| Bruce S McEwe. Early life influences on life-long patterns of behavior and health. Mental retardation and developmental disabilities research reviews. vol 9. issue 3. 2004-02-05. PMID:12953293. |
structural changes in the hippocampus and amygdala, which are important brain structures for cognition and emotion, are representative of what may be occurring throughout the brain as a result of allostatic load resulting from the chronic stress of a disorder such as depression. |
2004-02-05 |
2023-08-12 |
human |
| Klaus Fabel, Konstanze Fabel, Betty Tam, Daniela Kaufer, Armin Baiker, Natalie Simmons, Calvin J Kuo, Theo D Palme. VEGF is necessary for exercise-induced adult hippocampal neurogenesis. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656329. |
as in humans, chronic stress or depression in animals is accompanied by hippocampal dysfunction, and neurogenesis is correspondingly down regulated, in part, by the activity of the hypothalamic-pituitary-adrenal axis as well as glutamatergic and serotonergic networks. |
2004-01-26 |
2023-08-12 |
mouse |
| Tetsuji Itoh, Kohji Abe, Miwa Tokumura, Masahito Horiuchi, Osamu Inoue, Nobuhiro Ibi. Different regulation of adenylyl cyclase and rolipram-sensitive phosphodiesterase activity on the frontal cortex and hippocampus in learned helplessness rats. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575886. |
these findings indicated a delayed increase in pde4 activity leading to hypofunction of the camp-dependent signal transduction system in the frontal cortex and hippocampus of learned helplessness rats, suggesting that up-regulation of the camp-degradation system by pde4 may play a pivotal role in pathological states of chronic depression. |
2004-01-22 |
2023-08-12 |
rat |
| Yoshifumi Kagamiishi, Tsuneyuki Yamamoto, Shigenori Watanab. Hippocampal serotonergic system is involved in anxiety-like behavior induced by corticotropin-releasing factor. Brain research. vol 991. issue 1-2. 2004-01-22. PMID:14575894. |
taken with the evidence for hypersecretion of crf in patients with depression and anxiety-related disorders, our findings lead to the intriguing hypothesis that interaction between crf and 5-ht, especially in the ventral hippocampus, plays a role in the etiology of affective and anxiety disorders. |
2004-01-22 |
2023-08-12 |
rat |