| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Zhu, Chun-yan Bai, Lian-shi Zhuo, Wen-qi Fen. [Influence of electroacupuncture on hippocampal somatostatin (SS) and SS mRNA expression in chronic stress-induced depression rats]. Zhen ci yan jiu = Acupuncture research. vol 34. issue 3. 2009-10-08. PMID:19761111. |
[influence of electroacupuncture on hippocampal somatostatin (ss) and ss mrna expression in chronic stress-induced depression rats]. |
2009-10-08 |
2023-08-12 |
rat |
| Maria Załuska, Bertrand Janot. [Dehydroepiandrosteron (DHEA) in the mechanisms of stress and depression]. Psychiatria polska. vol 43. issue 3. 2009-10-02. PMID:19725420. |
the excess of cortisol is facilitating the development of depression by damaging the limbic, especially hippocampal neurons. |
2009-10-02 |
2023-08-12 |
human |
| J P Clement, A D Randall, J T Brow. Metabotropic glutamate receptor 1 activity generates persistent, N-methyl-D-aspartate receptor-dependent depression of hippocampal pyramidal cell excitability. The European journal of neuroscience. vol 29. issue 12. 2009-09-28. PMID:19490024. |
in extracellular recordings from hippocampal slices, dhpg-lde was expressed as a long-lasting depression of antidromic compound action potentials (caps) in ca1 or ca3 cells following a 4-min exposure to the group i mglur agonist (s)-dhpg. |
2009-09-28 |
2023-08-12 |
Not clear |
| Jingwei Tian, Fenghua Fu, Guisheng Li, Yubai Gao, Yunjuan Zhang, Qingsheng Meng, Changlu Li, Fu Li. Protections of SMND-309, a novel derivate of salvianolic acid B, on brain mitochondria contribute to injury amelioration in cerebral ischemia rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 16. issue 8. 2009-09-23. PMID:19481432. |
the results showed that smnd-309 decreased neurological deficit scores, reduced the number of dead hippocampal neuronal cells in accordance with its depression on mitochondria swelling degree, reactive oxygen species production, improvements on mitochondria swelling, energy metabolism, membrane potential level and mitochondrial respiratory chain complex activities. |
2009-09-23 |
2023-08-12 |
rat |
| Ja Wook Koo, Ronald S Duma. Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Current opinion in investigational drugs (London, England : 2000). vol 10. issue 7. 2009-09-22. PMID:19579172. |
uncontrollable stress, a major precipitant of depression in humans and in animal paradigms, impairs hippocampal neurogenesis, which is necessary for the behavioral effects of antidepressants in models of depression that require chronic treatment. |
2009-09-22 |
2023-08-12 |
Not clear |
| J M Gatt, C B Nemeroff, C Dobson-Stone, R H Paul, R A Bryant, P R Schofield, E Gordon, A H Kemp, L M William. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular psychiatry. vol 14. issue 7. 2009-09-10. PMID:19153574. |
the combination of met carrier status and exposure to els predicted reduced gray matter in hippocampus (p<0.001), and associated lateral prefrontal cortex (p<0.001) and, in turn, higher depression (p=0.005). |
2009-09-10 |
2023-08-12 |
human |
| April L Lussier, Hector J Caruncho, Lisa E Kalynchu. Repeated exposure to corticosterone, but not restraint, decreases the number of reelin-positive cells in the adult rat hippocampus. Neuroscience letters. vol 460. issue 2. 2009-09-02. PMID:19477232. |
much of the research on this topic has focused on stress-induced changes in hippocampal plasticity, specifically the idea that decreased hippocampal plasticity could be a precipitating factor for depression. |
2009-09-02 |
2023-08-12 |
rat |
| S-T Hong, C-B Choi, C Park, H-Y Moon, K S Hong, C Cheong, J-H Chae, B-Y Cho. Specific hippocampal choline decrease in an animal model of depression. The British journal of radiology. vol 82. issue 979. 2009-08-28. PMID:19221187. |
specific hippocampal choline decrease in an animal model of depression. |
2009-08-28 |
2023-08-12 |
rat |
| S-T Hong, C-B Choi, C Park, H-Y Moon, K S Hong, C Cheong, J-H Chae, B-Y Cho. Specific hippocampal choline decrease in an animal model of depression. The British journal of radiology. vol 82. issue 979. 2009-08-28. PMID:19221187. |
a decreased level of the hippocampal choline signal was found in patients with depression in previous proton magnetic resonance spectroscopy ((1)h-mrs) studies. |
2009-08-28 |
2023-08-12 |
rat |
| S-T Hong, C-B Choi, C Park, H-Y Moon, K S Hong, C Cheong, J-H Chae, B-Y Cho. Specific hippocampal choline decrease in an animal model of depression. The British journal of radiology. vol 82. issue 979. 2009-08-28. PMID:19221187. |
it suggests that decreased cho/cr and cho/naa ratios in the left hippocampal regions might be considered to be biomarkers in rats with depression. |
2009-08-28 |
2023-08-12 |
rat |
| I G Sil'ki. Characteristics of the functioning of the hippocampal formation in waking and paradoxical sleep. Neuroscience and behavioral physiology. vol 39. issue 6. 2009-08-27. PMID:19513850. |
analysis of published data identifying different neurotransmitter concentrations in the brain in paradoxical sleep and waking and data on the influences of neurotransmitters on the efficiency of the synaptic inputs to hippocampal neurons led to the conclusion that increases in the acetylcholine, cortisol, and dopamine concentrations during paradoxical sleep, with simultaneous reductions in serotonin and noradrenaline levels, may lead synergistically to a significant depression of transmission efficiency in polysynaptic pathways running through the hippocampus (i.e., the perforant path to neurons of the dentate gyrus, the pathway from the dentate gyrus to field ca3, from field ca3 to field ca1, and from field ca1 to the subiculum) but also to potentiation of the efficiency of the perforant path to pyramidal neurons of fields ca1 and ca3 and increases in the efficiency of associative connections between neurons in field ca3. |
2009-08-27 |
2023-08-12 |
Not clear |
| b' Magdalena Szyma\\xc5\\x84ska, Bogus\\xc5\\x82awa Budziszewska, Lucylla Jaworska-Feil, Agnieszka Basta-Kaim, Marta Kubera, Monika Le\\xc5\\x9bkiewicz, Magdalena Regulska, W\\xc5\\x82adys\\xc5\\x82aw Laso\\xc5\\x8. The effect of antidepressant drugs on the HPA axis activity, glucocorticoid receptor level and FKBP51 concentration in prenatally stressed rats. Psychoneuroendocrinology. vol 34. issue 6. 2009-08-25. PMID:19195790.' |
these data indicate that the increase in hippocampal gr level and low concentration of fkbp51 in the frontal cortex may be responsible for enhanced glucocorticoid action in depression. |
2009-08-25 |
2023-08-12 |
rat |
| Michael J Robinson, Sara E Edwards, Smriti Iyengar, Frank Bymaster, Michael Clark, Wayne Kato. Depression and pain. Frontiers in bioscience (Landmark edition). vol 14. 2009-08-25. PMID:19482603. |
we describe anatomical structures that are activated and/or altered in response to both depression and pain--examples include the insular cortex, the prefrontal cortex, the anterior cingulate cortex, the amygdala, and the hippocampus. |
2009-08-25 |
2023-08-12 |
Not clear |
| Łukasz R Drzyzga, Agnieszka Marcinowska, Ewa Obuchowic. Antiapoptotic and neurotrophic effects of antidepressants: a review of clinical and experimental studies. Brain research bulletin. vol 79. issue 5. 2009-08-21. PMID:19480984. |
in this paper, we put emphasis on the contribution of hippocampal atrophy, increased cell death and alterations in trophic factors to the pathogenesis of depression and their relationship to the potential of antidepressants to reverse these changes by modulating trophic factor cascades and preventing apoptosis. |
2009-08-21 |
2023-08-12 |
Not clear |
| Łukasz R Drzyzga, Agnieszka Marcinowska, Ewa Obuchowic. Antiapoptotic and neurotrophic effects of antidepressants: a review of clinical and experimental studies. Brain research bulletin. vol 79. issue 5. 2009-08-21. PMID:19480984. |
first, evidences for increased hippocampal atrophy and cell death in depression are discussed, followed by a review of selected studies of special interest that concern antiapoptotic action of antidepressant drugs. |
2009-08-21 |
2023-08-12 |
Not clear |
| b' M Pavl\\xc3\\xadkov\\xc3\\xa1, Z Tatarkov\\xc3\\xa1, M Sivonov\\xc3\\xa1, P Kaplan, O Krizanov\\xc3\\xa1, J Lehotsk\\xc3\\xb. Alterations induced by ischemic preconditioning on secretory pathways Ca2+-ATPase (SPCA) gene expression and oxidative damage after global cerebral ischemia/reperfusion in rats. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19288187.' |
our experiments conclusively showed iri-induced depression of spca activity and lipo- and protein oxidation in rat hippocampal membranes. |
2009-08-19 |
2023-08-12 |
rat |
| b' M Pavl\\xc3\\xadkov\\xc3\\xa1, Z Tatarkov\\xc3\\xa1, M Sivonov\\xc3\\xa1, P Kaplan, O Krizanov\\xc3\\xa1, J Lehotsk\\xc3\\xb. Alterations induced by ischemic preconditioning on secretory pathways Ca2+-ATPase (SPCA) gene expression and oxidative damage after global cerebral ischemia/reperfusion in rats. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19288187.' |
ipc partially suppresses lipo- and protein oxidation in hippocampal membranes and leads to partiall rovery of the ischemic-induced depression of spca activity. |
2009-08-19 |
2023-08-12 |
rat |
| M A Flerov, V G Shalyapin. Free-radical lipid oxidation in the brains of active and passive rats during the development of post-stress depression. Neuroscience and behavioral physiology. vol 39. issue 5. 2009-08-18. PMID:19430977. |
free-radical lipid oxidation was studied in the cerebral cortex, striatum, hippocampus, and hypothalamus of kha and kla rats (koltushi high and low avoidance) during the development of post-stress depression. |
2009-08-18 |
2023-08-12 |
rat |
| Marco Mula, Francesco Monac. Antiepileptic drugs and psychopathology of epilepsy: an update. Epileptic disorders : international epilepsy journal with videotape. vol 11. issue 1. 2009-08-05. PMID:19258231. |
depression seems to be linked with aeds potentiating gabaergic neurotransmission in patients with limbic system abnormalities such as hippocampal sclerosis. |
2009-08-05 |
2023-08-12 |
Not clear |
| N Doreulee, M Alania, M Chikovani, B Chkhartishvili, C Skhirtladz. Orexin-A induces long-term depression of nmda responses in CA-1 field of hippocampal slices. Georgian medical news. issue 169. 2009-07-20. PMID:19430048. |
orexin-a mediated depression starts after 7-10 min of application, which is sufficient for ne release from adrenergic terminals in the hippocampus. |
2009-07-20 |
2023-08-12 |
Not clear |