| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tengyu Gu, Jing Dong, Jing Ge, Jialu Feng, Xiaoliu Liu, Yun Chen, Jianfeng Li. Neurotoxic lesions of the anterior claustrum influence cued fear memory in rats. Frontiers in psychiatry. vol 15. 2024-05-06. PMID:38707622. |
it is proposed that dysfunction or malfunction of the cla might be the pathology of some brain diseases, including stress-induced depression and anxiety. |
2024-05-06 |
2024-05-08 |
rat |
| Charline G Padilha, Claudio V D M Ribeiro, Dimas E Oliveir. Milk fatty acids as covariates in multiple regression analysis is a robust approach to model the decrease in milk fat concentration and yield in small ruminants. Journal of animal physiology and animal nutrition. 2022-11-23. PMID:36415910. |
milk fat depression (mfd) syndrome has been associated with the antilipogenic effects of trans-10 fatty acids (fa), such as t10, c12-cla (cla) and t10-18:1 (t10). |
2022-11-23 |
2023-08-14 |
Not clear |
| Menglu Zhang, Tong Fu, Qixue Huang, Zhiyang Xing, Jingna Yang, Wenyan Lu, Mingyue Hu, Li Qiang Han, Juan J Loor, Teng Yun Ga. Size, number and phospholipid composition of milk fat globules are affected by dietary conjugated linoleic acid. Journal of animal physiology and animal nutrition. 2022-11-10. PMID:36353940. |
the aim of this study is to induce milk fat depression via dietary conjugated linoleic acid (cla) supplementation to study mfg size parameters, number and glycerophospholipid composition. |
2022-11-10 |
2023-08-14 |
Not clear |
| Qi Xue Huang, Jingna Yang, Mingyue Hu, Wenyan Lu, Kai Zhong, Yueying Wang, Guoyu Yang, Juan J Loor, Liqiang Ha. Milk fat globule membrane proteins are involved in controlling the size of milk fat globules during conjugated linoleic acid-induced milk fat depression. Journal of dairy science. 2022-09-29. PMID:36175227. |
we previously detected a decrease in the size of fat globules during conjugated linoleic acid (cla)-induced milk fat depression (mfd), and other studies have reported that some mfgm proteins play a central role in regulating mammary cellular lipid droplet size. |
2022-09-29 |
2023-08-14 |
cattle |
| A R Bayat, A Razzaghi, M Sari, P Kairenius, A Tröscher, E Trevisi, J Vilkk. The effect of dietary rumen-protected trans-10,cis-12 conjugated linoleic acid or a milk fat-depressing diet on energy metabolism, inflammation, and oxidative stress of dairy cows in early lactation. Journal of dairy science. 2022-02-06. PMID:35123782. |
the objective of this study was to determine the effects of milk fat depression induced by supplementing conjugated linoleic acid (cla; trans-10,cis-12 and cis-9,trans-11 cla) or feeding a higher starch and oil-containing diet (hso) on metabolic changes in dairy cows after calving. |
2022-02-06 |
2023-08-13 |
Not clear |
| A R Bayat, A Razzaghi, M Sari, P Kairenius, A Tröscher, E Trevisi, J Vilkk. The effect of dietary rumen-protected trans-10,cis-12 conjugated linoleic acid or a milk fat-depressing diet on energy metabolism, inflammation, and oxidative stress of dairy cows in early lactation. Journal of dairy science. 2022-02-06. PMID:35123782. |
this study provides evidence that milk fat depression induced by feeding hso (as well as cla) decreased milk fat secretion and improved eb compared with con in early lactation. |
2022-02-06 |
2023-08-13 |
Not clear |
| Nana Ma, Guozhen Wei, Hongzhu Zhang, Hongyu Dai, Animesh Chandra Roy, Xiaoli Shi, Guangjun Chang, Xiangzhen She. Cis-9, Trans-11 CLA Alleviates Lipopolysaccharide-Induced Depression of Fatty Acid Synthesis by Inhibiting Oxidative Stress and Autophagy in Bovine Mammary Epithelial Cells. Antioxidants (Basel, Switzerland). vol 11. issue 1. 2022-01-21. PMID:35052560. |
cis-9, trans-11 cla alleviates lipopolysaccharide-induced depression of fatty acid synthesis by inhibiting oxidative stress and autophagy in bovine mammary epithelial cells. |
2022-01-21 |
2023-08-13 |
cattle |
| G C De Aguiar, R Horstmann, C G Padilha, C V D M Ribeiro, D E De Oliveir. Stearic acid does not overcome The British journal of nutrition. 2021-10-27. PMID:34704550. |
in conclusion, stearic acid supplementation did not increase milk fat synthesis and did not overcome the cla-induced milk fat depression when associated with trans-10, cis-12 cla. |
2021-10-27 |
2023-08-13 |
Not clear |
| Liang Chen, Andrea J Lengi, Benjamin A Cor. The inhibitory effect of trans-10,cis-12 conjugated linoleic acid on sterol regulatory element binding protein-1 activation in bovine mammary epithelial cells involved reduced proteasomal degradation of insulin-induced gene-1. Journal of dairy science. vol 104. issue 10. 2021-09-23. PMID:34275626. |
trans-10,cis-12 conjugated linoleic acid (t10,c12 cla) is well recognized as a key cla isomer responsible for the reduction in milk fat synthesis that leads to milk fat depression in dairy cows. |
2021-09-23 |
2023-08-13 |
cattle |
| H B Shi, D M Tai, C Wang, J X Liu, J J Loor, H Y Li. Short communication: The antilipogenic effect of trans-10,cis-12 conjugated linoleic acid in bovine mammary epithelial cells is associated with proteasome activity and ATP production. Journal of dairy science. vol 103. issue 10. 2020-12-21. PMID:32828501. |
to investigate whether proteasomes play a role in milk fat depression induced by trans-10,cis-12 conjugated linoleic acid (t10,c12 cla), a bovine mammary epithelial cell line was treated with t10,c12 cla for 24 h before analysis of lipogenic protein abundance. |
2020-12-21 |
2023-08-13 |
cattle |
| H B Shi, D M Tai, C Wang, J X Liu, J J Loor, H Y Li. Short communication: The antilipogenic effect of trans-10,cis-12 conjugated linoleic acid in bovine mammary epithelial cells is associated with proteasome activity and ATP production. Journal of dairy science. vol 103. issue 10. 2020-12-21. PMID:32828501. |
collectively, the current data highlight a role of proteasomes and intracellular atp concentrations in the antilipogenic effect induced by t10,c12 cla that leads to milk fat depression. |
2020-12-21 |
2023-08-13 |
cattle |
| Z Y Xing, M L Zhang, Y Y Wang, G Y Yang, L Q Han, J J Loo. Short communication: A decrease in diameter of milk fat globules accompanies milk fat depression induced by conjugated linoleic acid supplementation in lactating dairy cows. Journal of dairy science. vol 103. issue 6. 2020-10-07. PMID:32307178. |
the aim of this study was to evaluate the effect of conjugated linoleic acid (cla) on the size and distribution of mfg during milk fat depression in dairy cows. |
2020-10-07 |
2023-08-13 |
Not clear |
| Z Y Xing, M L Zhang, Y Y Wang, G Y Yang, L Q Han, J J Loo. Short communication: A decrease in diameter of milk fat globules accompanies milk fat depression induced by conjugated linoleic acid supplementation in lactating dairy cows. Journal of dairy science. vol 103. issue 6. 2020-10-07. PMID:32307178. |
overall, the data suggest that the milk fat depression induced by cla is accompanied by a decrease in average diameter of mfg. |
2020-10-07 |
2023-08-13 |
Not clear |
| Aroa Suárez-Vega, Beatriz Gutiérrez-Gil, Pablo G Toral, Gonzalo Hervás, Juan José Arranz, Pilar Fruto. Conjugated linoleic acid (CLA)-induced milk fat depression: application of RNA-Seq technology to elucidate mammary gene regulation in dairy ewes. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30872673. |
conjugated linoleic acid (cla)-induced milk fat depression: application of rna-seq technology to elucidate mammary gene regulation in dairy ewes. |
2020-09-30 |
2023-08-13 |
Not clear |
| Aroa Suárez-Vega, Beatriz Gutiérrez-Gil, Pablo G Toral, Gonzalo Hervás, Juan José Arranz, Pilar Fruto. Conjugated linoleic acid (CLA)-induced milk fat depression: application of RNA-Seq technology to elucidate mammary gene regulation in dairy ewes. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30872673. |
milk fat depression (mfd) is characterized by a reduction in the content of milk fat, presumably caused by the anti-lipogenic effects of rumen biohydrogenation intermediates, such as trans-10 cis-12 conjugated linoleic acid (cla). |
2020-09-30 |
2023-08-13 |
Not clear |
| Luisa Cigliano, Maria Stefania Spagnuolo, Floriana Boscaino, Ida Ferrandino, Antonio Monaco, Teresa Capriello, Ennio Cocca, Lucia Iannotta, Lucia Treppiccione, Diomira Luongo, Francesco Maurano, Mauro Rossi, Paolo Bergam. Dietary Supplementation with Fish Oil or Conjugated Linoleic Acid Relieves Depression Markers in Mice by Modulation of the Nrf2 Pathway. Molecular nutrition & food research. vol 63. issue 21. 2020-07-16. PMID:31398773. |
as fish oil (fo) and conjugated linoleic acid (cla) are known nrf2 inducers, their protective ability is comparatively evaluated in a murine model of depression (mrl/mpj-fas |
2020-07-16 |
2023-08-13 |
mouse |
| Natalie L Urrutia, Monica Toledo, Michel Baldin, Jennifer L Ford, Michael H Green, Kevin J Harvatin. Kinetics of trans-10, cis-12-conjugated linoleic acid transfer to plasma and milk following an abomasal bolus in lactating dairy cows. The British journal of nutrition. vol 120. issue 3. 2019-09-04. PMID:30051796. |
trans-10, cis-12-conjugated linoleic acid (cla) is a potent bioactive fatty acids (fa) that causes milk fat depression in lactating animals. |
2019-09-04 |
2023-08-13 |
Not clear |
| Nanbing Qin, Ali-Reza Bayat, Erminio Trevisi, Andrea Minuti, Piia Kairenius, Sirja Viitala, Mervi Mutikainen, Heidi Leskinen, Kari Elo, Tuomo Kokkonen, Johanna Vilkk. Dietary supplement of conjugated linoleic acids or polyunsaturated fatty acids suppressed the mobilization of body fat reserves in dairy cows at early lactation through different pathways. Journal of dairy science. vol 101. issue 9. 2019-04-08. PMID:29960784. |
to investigate the metabolic changes in the adipose tissue (at) of dairy cows under milk fat depression (mfd), 30 cows were randomly allocated to a control diet, a conjugated linoleic acid (cla)-supplemented diet, or a high-starch diet supplemented with a mixture of sunflower and fish oil (2:1; as hso diet) from 1 to 112 d in milk. |
2019-04-08 |
2023-08-13 |
Not clear |
| E C Sandri, M Camêra, E M Sandri, K J Harvatine, D E De Oliveir. Peroxisome proliferator-activated receptor gamma (PPARγ) agonist fails to overcome trans-10, cis-12 conjugated linoleic acid (CLA) inhibition of milk fat in dairy sheep. Animal : an international journal of animal bioscience. vol 12. issue 7. 2019-03-15. PMID:29122042. |
the trans-10, cis-12 conjugated linoleic acid (cla) causes milk fat depression by downregulating expression of genes and transcription factors involved in lipogenesis and it has been proposed that peroxisome proliferator-activated receptor gamma (pparγ) can be inhibited by trans-10, cis-12 cla. |
2019-03-15 |
2023-08-13 |
Not clear |
| Kevin J Harvatine, Y R Boisclair, Dale E Bauma. Time-dependent effect of trans-10,cis-12 conjugated linoleic acid on gene expression of lipogenic enzymes and regulators in mammary tissue of dairy cows. Journal of dairy science. vol 101. issue 8. 2019-02-08. PMID:29803423. |
trans-10,cis-12 conjugated linoleic acid (cla) has been identified as an intermediate of rumen fatty acid biohydrogenation that caused milk fat depression (mfd) in the dairy cow. |
2019-02-08 |
2023-08-13 |
Not clear |