| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyunji Cho, Miyea Jo, Haemin Oh, Yunjung Lee, Yongsoon Par. Synergistic antidepressant-like effect of n-3 polyunsaturated fatty acids and probiotics through the brain-gut axis in rats exposed to chronic mild stress. The Journal of nutritional biochemistry. 2023-03-24. PMID:36963732. |
we hypothesized that n-3 pufa combined with live and dead probiotics synergistically improves depression by modulating the hypothalamic-pituitary-adrenal (hpa) axis and serotonergic pathways through the brain-gut axis. |
2023-03-24 |
2023-08-14 |
rat |
| Barbara Emons, Larissa Arning, Vera-Estelle Makulla, Maria-Theresia Suchy, Dimitrios Tsikas, Thomas Lücke, Jörg T Epplen, Georg Juckel, Patrik Rose. Endocannabinergic modulation of central serotonergic activity in healthy human volunteers. Annals of general psychiatry. vol 22. issue 1. 2023-03-18. PMID:36932421. |
the serotonergic and the endocannabinoid system are involved in the etiology of depression. |
2023-03-18 |
2023-08-14 |
human |
| Cheng-Teng Ip, Melanie Ganz, Brice Ozenne, Sebastian Olbrich, Vincent Beliveau, Vibeke H Dam, Kristin Köhler-Forsberg, Martin B Jørgensen, Vibe G Frøkjær, Gitte M Knudse. Association between the loudness dependence of auditory evoked potential, serotonergic neurotransmission and treatment outcome in patients with depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 70. 2023-03-02. PMID:36863106. |
association between the loudness dependence of auditory evoked potential, serotonergic neurotransmission and treatment outcome in patients with depression. |
2023-03-02 |
2023-08-14 |
Not clear |
| Ana Salomé Correia, Armando Cardoso, Nuno Val. Oxidative Stress in Depression: The Link with the Stress Response, Neuroinflammation, Serotonin, Neurogenesis and Synaptic Plasticity. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36830028. |
keeping in mind the importance of a detailed study about cellular and molecular mechanisms that are present in depression, this review focuses on the link between oxidative stress and the stress response, neuroinflammation, serotonergic pathways, neurogenesis, and synaptic plasticity's imbalances present in depression. |
2023-02-25 |
2023-08-14 |
Not clear |
| Guy M Goodwin, Megan Croal, Lindsey Marwood, Ekaterina Malievskai. Unblinding and demand characteristics in the treatment of depression. Journal of affective disorders. 2023-02-13. PMID:36781142. |
psychedelic experience for the treatment of depression must be unblinding, but the effect results directly from serotonergic receptor activation and changes in brain connectivity. |
2023-02-13 |
2023-08-14 |
human |
| Eyyup Murat Efendioglu, Ahmet Cigiloglu, Ercument Ozturk, Zeynel Abidin Oztur. Bone mineral density response to antiosteoporotic drugs in older depressed adults. Archives of osteoporosis. vol 18. issue 1. 2023-02-13. PMID:36781548. |
we demonstrate that the presence of depression and/or serotonergic antidepressant use was associated with non-response to osteoporosis treatment in older adults. |
2023-02-13 |
2023-08-14 |
Not clear |
| Adonis Sfera, Sabine Hazan, Zisis Kozlakidis, Carolina Klei. Microbiota-derived psychedelics: Lessons from COVID-19. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2023-02-08. PMID:36753370. |
the use of the psychotomimetic anesthetic, ketamine, for treatment-resistant depression has reawakened the interest in endogenous serotonergic hallucinogens, especially tryptamine and n,n-dimethyltryptamine (dmt), which are beneficial for depression but associated with psychosis.in this editorial, we take a closer look at the role of the microbiome in psychopathology, attempting to answer 2 questions:1. |
2023-02-08 |
2023-08-14 |
Not clear |
| Adonis Sfera, Sabine Hazan, Zisis Kozlakidis, Carolina Klei. Microbiota-derived psychedelics: Lessons from COVID-19. Advances in clinical and experimental medicine : official organ Wroclaw Medical University. 2023-02-08. PMID:36753370. |
why may psychosis-predisposing serotonergic hallucinogens alleviate depression?2. |
2023-02-08 |
2023-08-14 |
Not clear |
| David Erritzoe, Beata R Godlewska, Gaia Rizzo, Graham E Searle, Claudio Agnorelli, Yvonne Lewis, Abhishekh H Ashok, Alessandro Colasanti, Iro Boura, Chloe Farrell, Hollie Parfitt, Oliver Howes, Jan Passchier, Roger N Gunn, Marios Politis, David J Nutt, Philip J Cowen, Gitte M Knudsen, Eugenii A Rabine. Brain Serotonin Release Is Reduced in Patients With Depression: A [ Biological psychiatry. 2023-01-12. PMID:36635177. |
brain serotonin release is reduced in patients with depression: a [ the serotonin hypothesis of depression proposes that diminished serotonergic (5-ht) neurotransmission is causal in the pathophysiology of the disorder. |
2023-01-12 |
2023-08-14 |
Not clear |
| Laura Dorado, Sara Rubio-Guerra, Adrián Valls-Carbó, Lourdes Ispierto, María Hernández-Pérez, Martí Paré, Dolores Vila. Hypoechogenicity of the raphe nuclei as a biomarker of migraine: A case-control study, review, and meta-analysis. Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2022-11-22. PMID:36415025. |
comorbidity between migraine and depression is bidirectional postulating a common mechanism of serotonergic dysfunction. |
2022-11-22 |
2023-08-14 |
Not clear |
| Vidya V Jadhav, Jian Han, Yewande Fasina, Scott H Harriso. Connecting gut microbiomes and short chain fatty acids with the serotonergic system and behavior in Frontiers in physiology. vol 13. 2022-11-21. PMID:36406988. |
dysfunctional behavioral phenotypes from the serotonergic system moreover occur in both birds and mammals with, for example, fp in chickens and depression in humans. |
2022-11-21 |
2023-08-14 |
chicken |
| Nurcan Üçeyler, Mira Schließer, Dimitar Evdokimov, Jakub Radziwon, Betty Feulner, Stefan Unterecker, Florian Rimmele, Uwe Walte. Reduced midbrain raphe echogenicity in patients with fibromyalgia syndrome. PloS one. vol 17. issue 11. 2022-11-17. PMID:36395116. |
transcranial ultrasonography revealed anechoic alteration of midbrain raphe in depression and anxiety disorders, suggesting affection of the central serotonergic system. |
2022-11-17 |
2023-08-14 |
Not clear |
| Hendrik Bussmann, Hanns Häberlein, Georg Boonen, Jürgen Drewe, Veronika Butterweck, Sebastian Franke. Effect of St. John's wort extract Ze 117 on the lateral mobility of β Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-11-17. PMID:36395608. |
effect of st. john's wort extract ze 117 on the lateral mobility of β depression has been associated with altered signal transduction of serotonergic, dopaminergic and adrenergic neurotransmitter systems in the brain. |
2022-11-17 |
2023-08-14 |
Not clear |
| Kurt A Jellinge. The pathobiological basis of depression in Parkinson disease: challenges and outlooks. Journal of neural transmission (Vienna, Austria : 1996). 2022-11-02. PMID:36322206. |
although its diagnosis is based on standard criteria, due to overlap with other symptoms related to pd or to side effects of treatment, depression is frequently underdiagnosed and undertreated. dpd has been related to a variety of pathogenic mechanisms associated with the underlying neurodegenerative process, in particular dysfunction of neurotransmitter systems (dopaminergic, serotonergic and noradrenergic), as well as to disturbances of cortico-limbic, striato-thalamic-prefrontal, mediotemporal-limbic networks, with disruption in the topological organization of functional mood-related, motor and other essential brain network connections due to alterations in the blood-oxygen-level-dependent (bold) fluctuations in multiple brain areas. |
2022-11-02 |
2023-08-14 |
Not clear |
| Ana Salomé Correia, Isabel Silva, José Carlos Oliveira, Henrique Reguengo, Nuno Val. Serotonin Type 3 Receptor Is Potentially Involved in Cellular Stress Induced by Hydrogen Peroxide. Life (Basel, Switzerland). vol 12. issue 10. 2022-10-27. PMID:36295079. |
depression is a disease with several molecular mechanisms involved, such as problems in the serotonergic pathway. |
2022-10-27 |
2023-08-14 |
Not clear |
| Sai Dheeraj Gutlapalli, Vamsi Krishna Lavu, Rana Abdelwahab Mohamed, Ruimin Huang, Shanthi Potla, Sushen Bhalla, Yousif Al Qabandi, Savitri Aninditha Nandula, Chinmayi Sree Boddepalli, Pousette Hami. The Risk of Fatal Arrhythmias in Post-Myocardial Infarction Depression in Association With Venlafaxine. Cureus. vol 14. issue 9. 2022-10-19. PMID:36258960. |
venlafaxine is a second line anti-depressant and the most commonly used in the treatment of selective serotonin reuptake inhibitor nonresponders in major depression; due to its effects on the noradrenergic and serotonergic systems as a serotonin and norepinephrine reuptake inhibitor, there has been considerable apprehension regarding its use in patients with cardiovascular diseases, particularly post-myocardial infarction depression, some of the feared adverse effects include qt prolongation, arrhythmias including torsades de pointes and sudden cardiac death. |
2022-10-19 |
2023-08-14 |
Not clear |
| Sai Dheeraj Gutlapalli, Keerthana Prakash, Kiran Maee Swarnakari, Meena Bai, Mohana Priya Manoharan, Rabab Raja, Aneeque Jamil, Denise Csendes, Aditya Desai, Darshi M Desai, Michael Alfons. The Risk of Fatal Arrhythmias Associated With Sertraline in Patients With Post-myocardial Infarction Depression. Cureus. vol 14. issue 9. 2022-10-14. PMID:36237772. |
it is preferred due to its central and peripheral actions on the serotonergic system in patients with mental health issues as well as cardiovascular disease, particularly post-myocardial infarction depression. |
2022-10-14 |
2023-08-14 |
Not clear |
| Li-Jing Du, Xin-Ning Zhang, Sha-Sha Li, Yuan-Fang Sun, Hui-Zi Jin, Shi-Kai Yan, Chuan-Gang Ha. Network pharmacological investigation into the mechanism of Kaixinsan powder for the treatment of depression. Metabolic brain disease. 2022-09-07. PMID:36070047. |
kegg pathway analysis highlighted the most significant pathways associated with depression treatment, including neuroactive ligand-receptor interaction pathway, serotonergic synapse pathway, pi3k-akt signaling pathway and mapk signaling pathway. |
2022-09-07 |
2023-08-14 |
Not clear |
| Nina K Popova, Anton S Tsybko, Vladimir S Naumenk. The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955946. |
being different multifactorial forms of psychopathology, aggression, depression and suicidal behavior, which is considered to be violent aggression directed against the self, have principal neurobiological links: preclinical and clinical evidence associates depression, aggression and suicidal behavior with dysregulation in central serotonergic (5-ht) neurotransmission. |
2022-08-12 |
2023-08-14 |
Not clear |
| Paraskevi Mavrogiorgou, Florian Seltsam, David Kiefner, Vera Flasbeck, Georg Jucke. Narcissism and central Serotonergic Neurotransmission in Depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2022-06-27. PMID:35757904. |
narcissism and central serotonergic neurotransmission in depression. |
2022-06-27 |
2023-08-14 |
Not clear |