| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron M Rozeboom, Huda Akil, Audrey F Seasholt. Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 11. 2007-05-14. PMID:17360585. |
although numerous stress-related molecules have been implicated in vulnerability to psychiatric illness, especially major depression and anxiety disorders, the role of the brain mineralocorticoid receptor (mr) in stress, depression, and affective function is not well defined. |
2007-05-14 |
2023-08-12 |
mouse |
| Sven Bölte, Susan Knecht, Fritz Poustk. A case-control study of personality style and psychopathology in parents of subjects with autism. Journal of autism and developmental disorders. vol 37. issue 2. 2007-05-01. PMID:16897383. |
reserved/schizoid, depression) compared to parents of subjects with ocd, eos and normative data, but not in comparison to mr parents. |
2007-05-01 |
2023-08-12 |
human |
| Julia C Lemos, Yu-Zhen Pan, Xiaohong Ma, Christophe Lamy, Adaure C Akanwa, Sheryl G Bec. Selective 5-HT receptor inhibition of glutamatergic and GABAergic synaptic activity in the rat dorsal and median raphe. The European journal of neuroscience. vol 24. issue 12. 2007-03-06. PMID:17229091. |
the dr and mr have differential roles in mediating stress, anxiety and depression. |
2007-03-06 |
2023-08-12 |
rat |
| Alexander Sartorius, Patrick Schloss, Barbara Vollmayr, Gabriele Ende, Claudia Neumann-Haefelin, Mathias Hoehn, Fritz A Hen. Correlation between MR-spectroscopic rat hippocampal choline levels and phospholipase A2. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 7. issue 4. 2007-02-23. PMID:17071545. |
hippocampal choline-containing compounds (cho) determined with 1h mr spectroscopy (mrs) are decreased in major depression episodes and return to baseline levels after antidepressive electroconvulsive therapy (ect). |
2007-02-23 |
2023-08-12 |
human |
| Minjie Wu, Caterina Rosano, Meryl Butters, Ellen Whyte, Megan Nable, Ryan Crooks, Carolyn C Meltzer, Charles F Reynolds, Howard J Aizenstei. A fully automated method for quantifying and localizing white matter hyperintensities on MR images. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17097277. |
the method is validated using the brain mr images acquired from eleven elderly subjects with late-onset late-life depression (lld) and eight elderly controls. |
2007-02-12 |
2023-08-12 |
human |
| Minjie Wu, Caterina Rosano, Meryl Butters, Ellen Whyte, Megan Nable, Ryan Crooks, Carolyn C Meltzer, Charles F Reynolds, Howard J Aizenstei. A fully automated method for quantifying and localizing white matter hyperintensities on MR images. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17097277. |
white matter hyperintensities (wmh), commonly found on t2-weighted flair brain mr images in the elderly, are associated with a number of neuropsychiatric disorders, including vascular dementia, alzheimer's disease, and late-life depression. |
2007-02-12 |
2023-08-12 |
human |
| Nader Binesh, Anand Kumar, Sun Hwang, Jim Mintz, M Albert Thoma. Neurochemistry of late-life major depression: a pilot two-dimensional MR spectroscopic study. Journal of magnetic resonance imaging : JMRI. vol 20. issue 6. 2005-04-21. PMID:15558563. |
neurochemistry of late-life major depression: a pilot two-dimensional mr spectroscopic study. |
2005-04-21 |
2023-08-12 |
Not clear |
| Kenichi Kashihara, Manabu Ohno, Yasuko Kats. [Psychoses in patients with Parkinson's disease; their frequency, phenomenology, and clinical correlates]. Rinsho shinkeigaku = Clinical neurology. vol 45. issue 1. 2005-03-29. PMID:15714992. |
there were no differences in age at admission, age at onset of parkinson's disease, duration of illness, amounts of levodopa and dopamine agonists received, hamilton's depression rating scores, and brain mr findings, including atrophy and ischemic changes. |
2005-03-29 |
2023-08-12 |
cat |
| Guo-Qiang Xing, Shani Russell, Maree J Webster, Robert M Pos. Decreased expression of mineralocorticoid receptor mRNA in the prefrontal cortex in schizophrenia and bipolar disorder. The international journal of neuropsychopharmacology. vol 7. issue 2. 2004-08-31. PMID:14741058. |
the mr mrna expression in the post-mortem prefrontal cortex of patients with major depression (md), bipolar (bp), and schizophrenic (sz) disorders and non-psychiatric controls (n=15 for each patient group, and n=14 for controls) was determined by in-situ hybridization. |
2004-08-31 |
2023-08-12 |
Not clear |
| Alexandre Urani, Peter Gas. Corticosteroid receptor transgenic mice: models for depression? Annals of the New York Academy of Sciences. vol 1007. 2004-03-25. PMID:14993071. |
certain mouse strains with specific alterations of gr or mr expression may represent genetic models of depression or at least have a predisposition to develop a depressive or a depression-resistant state upon exposure to stress. |
2004-03-25 |
2023-08-12 |
mouse |
| Elizabeth A Young, Juan F Lopez, Virginia Murphy-Weinberg, Stanley J Watson, Huda Aki. Mineralocorticoid receptor function in major depression. Archives of general psychiatry. vol 60. issue 1. 2003-01-23. PMID:12511169. |
because major depression is accompanied by increased glucocorticoid secretion and insensitivity to glucocorticoid feedback, and because glucocorticoids are capable of down-regulating mr and gr, we expected that major depression would be accompanied by decreased mr activity. |
2003-01-23 |
2023-08-12 |
Not clear |
| Mikhail Lomarev, Stewart Denslow, Ziad Nahas, Jeong-Ho Chae, Mark S George, Daryl E Bohnin. Vagus nerve stimulation (VNS) synchronized BOLD fMRI suggests that VNS in depressed adults has frequency/dose dependent effects. Journal of psychiatric research. vol 36. issue 4. 2002-10-29. PMID:12191626. |
six adults with recurrent depression were scanned inside a 1.5 t mr scanner. |
2002-10-29 |
2023-08-12 |
Not clear |
| Valeria Ayelli Edgar, Graciela A Cremaschi, Leonor Sterin-Borda, Ana María Genar. Altered expression of autonomic neurotransmitter receptors and proliferative responses in lymphocytes from a chronic mild stress model of depression: effects of fluoxetine. Brain, behavior, and immunity. vol 16. issue 4. 2002-08-22. PMID:12096882. |
we studied beta-adrenergic and muscarinic cholinergic receptor (mr) expression and proliferative response in lymphocytes from animals under chronic mild stress (cms) model of depression (cms animals). |
2002-08-22 |
2023-08-12 |
Not clear |
| M A Rogers, J L Bradshaw, J G Phillips, E Chiu, C Mileshkin, K Vaddad. Mental rotation in unipolar major depression. Journal of clinical and experimental neuropsychology. vol 24. issue 1. 2002-06-17. PMID:11935428. |
mr was employed with a sample of both melancholic (n=8) and non-melancholic (n=9) unipolar depressed patients and healthy controls (n=10) to determine if motor slowing associated with depression might be reflected in slowed motor preparation (as reflected in slope of the mr function) independent of actual motor slowing (overall response time). |
2002-06-17 |
2023-08-12 |
Not clear |
| V F Kichigina, T A Kudin. [Sensory reactions of hippocampal neurons in rabbit during functional suppression of theta rythm- controlling structures]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 51. issue 2. 2002-02-25. PMID:11548605. |
the mr blockade, which resulted in an enhancement of theta-modulation of the background activity of the hippocampal neurons, was followed by a depression of sensory responsiveness (only 46.7% of the neurons reactive before the blockade retained their responses). |
2002-02-25 |
2023-08-12 |
rabbit |
| C P Clark, L R Frank, G G Brow. Sleep deprivation, EEG, and functional MRI in depression: preliminary results. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 5 Suppl. 2001-12-28. PMID:11682279. |
two unmedicated patients with major depression and a matched control received quantitative perfusion mr images at baseline and after one night of partial sd (psd). |
2001-12-28 |
2023-08-12 |
Not clear |
| P Gass, H M Reichardt, T Strekalova, F Henn, F Tronch. Mice with targeted mutations of glucocorticoid and mineralocorticoid receptors: models for depression and anxiety? Physiology & behavior. vol 73. issue 5. 2001-12-04. PMID:11566214. |
using high throughput technologies for the identification of genes regulated by glucocorticoid receptor (gr) and mr in brain areas responsible for specific symptoms of stress-related disorders will yield potential new drug targets for the treatment of depression and anxiety. |
2001-12-04 |
2023-08-12 |
mouse |
| Z Nahas, C DeBrux, V Chandler, J P Lorberbaum, A M Speer, M A Molloy, C Liberatos, S C Risch, M S Georg. Lack of significant changes on magnetic resonance scans before and after 2 weeks of daily left prefrontal repetitive transcranial magnetic stimulation for depression. The journal of ECT. vol 16. issue 4. 2001-09-06. PMID:11314876. |
the authors performed t1-weighted three-dimensional volumetric magnetic resonance (mr) imaging on 22 depressed adults (15 active, 7 control) before and after they participated in a 2-week double-blinded, placebo-controlled trial of daily left prefrontal rtms for the treatment of depression (a total of 16,000 stimuli). |
2001-09-06 |
2023-08-12 |
Not clear |
| J R MacFall, M E Payne, J E Provenzale, K R Krishna. Medial orbital frontal lesions in late-onset depression. Biological psychiatry. vol 49. issue 9. 2001-08-23. PMID:11331089. |
early studies using magnetic resonance (mr) imaging suggested that subcortical vascular changes are more prevalent in late-life depression and that they may play a role in the pathophysiology of depression. |
2001-08-23 |
2023-08-12 |
human |
| I Heuser, M Deuschle, B Weber, G K Stalla, F Holsboe. Increased activity of the hypothalamus-pituitary-adrenal system after treatment with the mineralocorticoid receptor antagonist spironolactone. Psychoneuroendocrinology. vol 25. issue 5. 2000-08-03. PMID:10818284. |
we thus conclude that (1) the mr antagonist spironolactone affects hpa system regulation as reflected in the dex/crh test and (2) these findings are in accordance with the assumption that mr dysfunction may underlie hpa-system dysfunction in depression and/or aging. |
2000-08-03 |
2023-08-12 |
human |