Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Bryan G Nadeau, Elliott G Marchant, Shimon Amir, Ralph E Mistlberge. Thermoregulatory significance of immobility in the forced swim test. Physiology & behavior. 2022-01-22. PMID:35065081. |
the forced swim test (fst) is a widely used animal model of depression and antidepressant drug screen. |
2022-01-22 |
2023-08-13 |
rat |
Bryan G Nadeau, Elliott G Marchant, Shimon Amir, Ralph E Mistlberge. Thermoregulatory significance of immobility in the forced swim test. Physiology & behavior. 2022-01-22. PMID:35065081. |
immobility is said to reflect a state of lowered mood or "behavioral despair", but the validity of the fst as a model of depression has been questioned. |
2022-01-22 |
2023-08-13 |
rat |
Farajollah Jafari, Mahdi Goudarzvand, Ramin Hajikhani, Mostafa Qorbani, Jalal Solat. Pycnogenol ameliorates motor function and gene expressions of NF-ƙB and Nrf2 in a 6-hydroxydopamine-induced experimental model of Parkinson's disease in male NMRI mice. Naunyn-Schmiedeberg's archives of pharmacology. 2022-01-13. PMID:35024909. |
seven days after parkinson's model induction, the apomorphine test, the degree of catalepsy by bar test, the duration of immobility (depression) by forced swimming test (fst) were measured. |
2022-01-13 |
2023-08-13 |
mouse |
Hikmet Gumus, Rabia Ilgin, Basar Koc, Oguz Yuksel, Servet Kizildag, Guven Guvendi, Asli Karakilic, Sevim Kandis, Ferda Hosgorler, Mehmet Ates, Hasan Alacam, Nazan Uysa. A combination of ketogenic diet and voluntary exercise ameliorates anxiety and depression-like behaviors in Balb/c mice. Neuroscience letters. 2022-01-06. PMID:34990761. |
there was a negative correlation between bhb and the time spent in the closed arms of elevated plus maze (epm) or the time spent in periphery walls of open field test (oft) and the immobility time in forced swim test (fst) which all of them are indicators of low depression and anxiety levels. |
2022-01-06 |
2023-08-13 |
mouse |
Hui-Zhen Li, Ning-Xi Zeng, Kai-Ge Liu, Wu-Long Luo, Wen-Jun Lu, Li-Li W. [Preliminary study on cerebrospinal fluid proteomics of Erxian Decoction against neurogenesis impairment in late-onset depression]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 23. 2021-12-24. PMID:34951250. |
behavioral tests showed that sucrose consumption in spt, total traveling distance in oft, and times of crossing the platform in mwmt were all reduced(p<0.01) and the immobility time in fst was prolonged(p<0.01) in the lod group compared with those in the aged group, suggesting that lod rats had developed depression symptoms such as anhedonia, decreased locomotor activity ability, and cognitive dysfunction. |
2021-12-24 |
2023-08-13 |
rat |
Arnab Nandi, Garima Virmani, Aatmika Barve, Swananda Marath. DBscorer: An Open-Source Software for Automated Accurate Analysis of Rodent Behavior in Forced Swim Test and Tail Suspension Test. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34625460. |
here, we describe the development of depression behavior scorer (dbscorer), an open-source program installable on windows, with an intuitive graphical user interface (gui), that helps in accurate quantification of immobility behavior in fst and tst from video analysis. |
2021-12-11 |
2023-08-13 |
Not clear |
Shun Aoki, Satoshi Deyama, Rinako Sugie, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice. Behavioural brain research. vol 418. 2021-12-11. PMID:34801580. |
(1 ng) and intra-mpfc (50 pg/side) infusions of rve1 in the repeated psl-induced depression mouse model using the oft and fst after 5- and 6-day psl treatments, respectively. |
2021-12-11 |
2023-08-13 |
mouse |
Amalia Dávila-Hernández, Roberto González-González, Sonia Guzmán-Velázquez, Olivia Tania Hernández Hernández, Sergio R Zamudio, Lucía Martínez-Mot. Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats. Brain research bulletin. vol 173. 2021-12-09. PMID:33991609. |
post-weaning social isolated rodents exhibit pathophysiological changes associated with depression including adrenal axis hyperactivity, gonadal hormone level disturbances, molecular alterations in hippocampus, and immobility behavior in the forced swimming test (fst). |
2021-12-09 |
2023-08-13 |
rat |
Meiling Tang, Min Chen, Qiang L. Paeoniflorin ameliorates chronic stress-induced depression-like behavior in mice model by affecting ERK1/2 pathway. Bioengineered. vol 12. issue 2. 2021-12-07. PMID:34872456. |
sucrose preference test (spt), tail suspension test (tst), open field test (oft) and forced swimming test (fst) were used to assess depression symptoms. |
2021-12-07 |
2023-08-13 |
mouse |
Emily R Trunnell, Constança Carvalh. The forced swim test has poor accuracy for identifying novel antidepressants. Drug discovery today. vol 26. issue 12. 2021-12-03. PMID:34390862. |
of these, there were only three for which the fst appeared to positively predict antidepressant efficacy, but none are currently approved to treat any type of depression. |
2021-12-03 |
2023-08-13 |
Not clear |
Ning-Xin Qin, Yi-Ran Zhao, Wei-Hui Shi, Zhi-Yang Zhou, Ke-Xin Zou, Chuan-Jin Yu, Xia Liu, Ze-Han Dong, Yi-Ting Mao, Cheng-Liang Zhou, Jia-Le Yu, Xin-Mei Liu, Jian-Zhong Sheng, Guo-Lian Ding, Wen-Long Zhao, Yan-Ting Wu, He-Feng Huan. Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception. Reproduction (Cambridge, England). vol 162. issue 6. 2021-12-03. PMID:34605773. |
a battery of behaviour experiments for evaluating anxiety and depression levels, including the open field test (oft), elevated plus maze (epm) test, light/dark transition test (l/dtt), tail suspension test (tst), forced swimming test (fst), and sucrose preference test (spt) was carried out. |
2021-12-03 |
2023-08-13 |
mouse |
Sushma Maratha, Vijay Sharma, Vaibhav Wali. Antidepressant Like Effect of Ascorbic Acid in Mice: Possible Involvement of NO-sGC-cGMP Signaling. Neurochemical research. 2021-11-26. PMID:34825298. |
was administered to the mice and depression related behavior were determined using tail suspension test (tst) and forced swim test (fst). |
2021-11-26 |
2023-08-13 |
mouse |
Sushma Maratha, Vijay Sharma, Vaibhav Wali. Antidepressant Like Effect of Ascorbic Acid in Mice: Possible Involvement of NO-sGC-cGMP Signaling. Neurochemical research. 2021-11-26. PMID:34825298. |
reversed the depression like behavior in mice in tst and fst. |
2021-11-26 |
2023-08-13 |
mouse |
Hao Guo, Cuola Deji, Han Peng, Jinyu Zhang, Yuanyuan Chen, Yulei Zhang, Yunpeng Wan. The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice. Genes, brain, and behavior. vol 20. issue 8. 2021-11-11. PMID:34355499. |
cums procedure induced significant depression symptoms including the decreased sucrose preference, the less bodyweight gained, the decreased immobile latency and the increased immobile time both in forced swim test (fst) and tail suspension test (tst). |
2021-11-11 |
2023-08-13 |
mouse |
Ling Xu, Ming Jiao, Ze-Lin Cui, Qing-Ya Zhao, Yan Wang, Shu Chen, Jun-Jie Zhang, Yin-Hui Jin, Di Mu, Yu-Qin Yan. Enriched environment during adolescence modulates lipid metabolism and emotion-related behaviors in mice. Journal of applied animal welfare science : JAAWS. 2021-11-02. PMID:34470518. |
we first established an ee model in adolescent mice, dissected lipid metabolism, and further examined baseline level of anxiety and depression by multiple behavioral tests, including open field test (oft), elevated zero maze (ezm), tail suspension test (tst), and forced swimming test (fst). |
2021-11-02 |
2023-08-13 |
mouse |
Zackary A Cope, Maria L Lavadia, Aniek J M Joosen, Chuck J A van de Cappelle, Joseph C Lara, Alexandra Huval, Molly K Kwiatkowski, Marina R Picciotto, Yann S Mineur, Davide Dulcis, Jared W Youn. Converging evidence that short-active photoperiod increases acetylcholine signaling in the hippocampus. Cognitive, affective & behavioral neuroscience. vol 20. issue 6. 2021-10-25. PMID:32794101. |
elevating acetylcholine with the acetylcholinesterase inhibitor physostigmine induces depression symptoms in people and increases fst immobility in mice. |
2021-10-25 |
2023-08-13 |
mouse |
Héctor Miguel Mancha-Gutiérrez, Erika Estrada-Camarena, Lilian Mayagoitia-Novales, Elena López-Pacheco, Carolina López-Rubalcav. Chronic Social Defeat During Adolescence Induces Short- and Long-Term Behavioral and Neuroendocrine Effects in Male Swiss-Webster Mice. Frontiers in behavioral neuroscience. vol 15. 2021-10-22. PMID:34658806. |
twenty-four hours (mid-adolescence) or 4 weeks (early adulthood) later, mice were tested in two models of depression; the social interaction test (sit) and forced swimming test (fst); cognitive deficits were evaluated in the barnes maze (bm). |
2021-10-22 |
2023-08-13 |
mouse |
Mayur Kale, Nitin Nimje, Manish M Aglawe, Milind Umekar, Brijesh Taksande, Nandkishor Kotagal. Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats. Brain research. vol 1747. 2021-10-07. PMID:32758481. |
the present study investigated the role of the agmatinergic system in t2dm induced depression using forced swim test (fst) and anxiety in the elevated plus-maze (epm)in rats. |
2021-10-07 |
2023-08-13 |
rat |
Zuotian Wu, Gaohua Wang, Ling Xiao, Yanyan Wei, Huiling Wang, Lin Zhou, Limin Su. Resilience in the LPS-induced acute depressive-like behaviors: Increase of CRMP2 neuroprotection and microtubule dynamics in hippocampus. Brain research bulletin. vol 162. 2021-09-29. PMID:32645362. |
in the lps-induced depression group, body weight and sucrose preference index in spt were decreased, the immobility time in fst was increased, total distance, time in central zone and frequency of rearing in oft were decreased. |
2021-09-29 |
2023-08-13 |
rat |
Haitham S Mohammed, Yasser A Khadraw. Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression. Lasers in medical science. 2021-09-06. PMID:34487275. |
forced swimming test (fst) was used to verify the induction of animal model of depression and to screen the effect of antidepressant effect of low-level laser at the end of the experiment. |
2021-09-06 |
2023-08-13 |
rat |