| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V N Amirdzhanova, A E Karateev, E Yu Pogozheva, E S Filatova, R R Samigullina, V I Mazurov, O N Anoshenkova, N A Lapkina, A A Baranov, T Yu Grineva, A M Lila, E L Nasono. Are the Goals of Therapy Achievable in Patients with Rheumatoid Arthritis Receiving Upadacitinib in Real Clinical Practice? Doklady. Biochemistry and biophysics. vol 511. issue 1. 2023-10-13. PMID:37833604. |
activity was assessed according to the das28(esr), das28(crp), sdai, cdai; functional ability to haq; quality of life to the eq-5d; disease activity according to the patient's rapid-3 index; the level of depression and anxiety to the hads scale. |
2023-10-13 |
2023-10-15 |
Not clear |
| Harald Engler, Alexandra Brinkhoff, Benjamin Wilde, Andreas Kribben, Hana Rohn, Oliver Witzke, Manfred Schedlowski, Sven Benso. Endotoxin-induced physiological and psychological sickness responses in healthy humans: insights into the post-acute phase. Neuroimmunomodulation. 2023-10-05. PMID:37797587. |
the main focus was on associations between serum levels of c-reactive protein (crp) and affective symptoms as well as alterations in diurnal cortisol profile, two key features of inflammation-associated depression. |
2023-10-05 |
2023-10-07 |
Not clear |
| Zhuping Sun, Silu Chen, Hui Zhang, Xiaoqing Gu, Haiyan Ge, Jinglei Che. Changes of Serum C-Reactive Protein Level in Patients With Depressive Disorders After Treatment With Agomelatine Combined With Aerobic Exercise and Its Significance. Clinical neuropharmacology. vol 46. issue 5. 2023-09-25. PMID:37748002. |
this study investigated the therapeutic effect of agomelatine (ag) combined with aerobic exercise (ae) on patients with moderate-severe depression (msd) and the changes of the serum c-reactive protein (crp) level in patients after treatment as well as its significance. |
2023-09-25 |
2023-10-07 |
Not clear |
| Houxu Ning, Hao Zhou, Ning Yang, Jingru Ren, Haidong Wang, Weiguo Liu, Yang Zha. Effect of Zishen pingchan granules combined with pramipexole on serum BDNF, IL-1β, IL-6, CRP, TNF-α levels in depressed patients with Parkinson's disease: Results of a randomized, double-blind, controlled study. Experimental gerontology. 2023-09-21. PMID:37734668. |
this study aimed to investigate the impact of zpg on serum levels of brain-derived neurotrophic factor (bdnf), interleukin-1β (il-1β), interleukin-6 (il-6), c-reactive protein (crp), and tumor necrosis factor-α (tnf-α) in pd patients with depression. |
2023-09-21 |
2023-10-07 |
Not clear |
| Dandan Xu, Yayun Xu, Xinran Gao, Mengyu Yan, Chen Zhang, Xian Wu, Qingrong Xia, Jinfang G. Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats. International immunopharmacology. vol 124. issue Pt B. 2023-09-17. PMID:37717319. |
moreover, tocilizumab could alleviate the "inflammatory storm" and impaired hippocampal synaptic plasticity in lps-challenged depression rats, inhibiting the hyperactivation of astrocyte and microglia, decreasing the peripheral and central abundance of il-6, crp, and tnf-α, and balancing the hippocampal expression levels of synaptic plasticity-associated proteins and key molecular in wnt/β-catenin signaling pathway. |
2023-09-17 |
2023-10-07 |
human |
| Vasilios Karageorgiou, Francesco Casanova, Jessica O'Loughlin, Harry Green, Trevelyan J McKinley, Jack Bowden, Jessica Tyrrel. Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study. BMC medicine. vol 21. issue 1. 2023-09-14. PMID:37710313. |
we aim to investigate inflammation, proxied by c-reactive protein (crp) levels, and body mass index (bmi) as putative causal risk factors for depression and subsequent treatment resistance, leveraging genetic information to avoid confounding via mendelian randomisation (mr). |
2023-09-14 |
2023-10-07 |
Not clear |
| Zhuping Sun, Silu Chen, Hui Zhang, Xiaoqing Gu, Haiyan Ge, Jinglei Che. Changes of Serum C-Reactive Protein Level in Patients With Depressive Disorders After Treatment With Agomelatine Combined With Aerobic Exercise and Its Significance. Clinical neuropharmacology. 2023-09-11. PMID:37695861. |
this study investigated the therapeutic effect of agomelatine (ag) combined with aerobic exercise (ae) on patients with moderate-severe depression (msd) and the changes of the serum c-reactive protein (crp) level in patients after treatment as well as its significance. |
2023-09-11 |
2023-10-07 |
Not clear |
| Christina A Metcalf, Rachel L Johnson, Korrina A Duffy, Ellen W Freeman, Mary D Sammel, C Neill Epperso. Depressed, stressed, and inflamed: C-reactive protein linked with depression symptoms in midlife women with both childhood and current life stress. Stress and health : journal of the International Society for the Investigation of Stress. 2023-09-08. PMID:37679965. |
for women in midlife with exposure to high adverse childhood experiences and multiple current life stressors, elevated levels of crp were uniquely associated with clinically significant depression symptoms. |
2023-09-08 |
2023-10-07 |
human |
| Guy Hindley, Ole Kristian Drange, Aihua Lin, Gleda Kutrolli, Alexey A Shadrin, Nadine Parker, Kevin S O'Connell, Linn Rødevand, Weiqiu Cheng, Shahram Bahrami, Naz Karadag, Børge Holen, Piotr Jaholkowski, Markos Tesfaye Woldeyohannes, Srdjan Djurovic, Anders M Dale, Oleksandr Frei, Thor Ueland, Olav B Smeland, Ole A Andreasse. Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders. Psychoneuroendocrinology. vol 157. 2023-09-02. PMID:37659117. |
recent findings have suggested a protective effect of the genetic liability to elevated crp on schizophrenia risk and a causative effect on depression despite weak genetic correlations, while causal relationships with bipolar disorder were inconclusive. |
2023-09-02 |
2023-09-07 |
Not clear |
| Guy Hindley, Ole Kristian Drange, Aihua Lin, Gleda Kutrolli, Alexey A Shadrin, Nadine Parker, Kevin S O'Connell, Linn Rødevand, Weiqiu Cheng, Shahram Bahrami, Naz Karadag, Børge Holen, Piotr Jaholkowski, Markos Tesfaye Woldeyohannes, Srdjan Djurovic, Anders M Dale, Oleksandr Frei, Thor Ueland, Olav B Smeland, Ole A Andreasse. Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders. Psychoneuroendocrinology. vol 157. 2023-09-02. PMID:37659117. |
genome-wide association studies for crp (n = 575,531), bipolar disorder (n = 413,466), depression (n = 480,359), and schizophrenia (n = 130,644) were used in causal mixture models to compare crp with psychiatric disorders based on polygenicity, discoverability, and genome-wide genetic overlap. |
2023-09-02 |
2023-09-07 |
Not clear |
| Guy Hindley, Ole Kristian Drange, Aihua Lin, Gleda Kutrolli, Alexey A Shadrin, Nadine Parker, Kevin S O'Connell, Linn Rødevand, Weiqiu Cheng, Shahram Bahrami, Naz Karadag, Børge Holen, Piotr Jaholkowski, Markos Tesfaye Woldeyohannes, Srdjan Djurovic, Anders M Dale, Oleksandr Frei, Thor Ueland, Olav B Smeland, Ole A Andreasse. Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders. Psychoneuroendocrinology. vol 157. 2023-09-02. PMID:37659117. |
gene-set enrichment analyses identified predominantly cns-related gene sets for crp and each of depression and schizophrenia, and basic cellular processes for crp and bipolar disorder. |
2023-09-02 |
2023-09-07 |
Not clear |
| Kaiping Burrows, Breanna A McNaughton, Leandra K Figueroa-Hall, Philip A Spechler, Rayus Kuplicki, Teresa A Victor, Robin Aupperle, Sahib S Khalsa, Jonathan B Savitz, T Kent Teague, Martin P Paulus, Jennifer L Stewar. Elevated serum leptin is associated with attenuated reward anticipation in major depressive disorder independent of peripheral C-reactive protein levels. Scientific reports. vol 13. issue 1. 2023-07-14. PMID:37443383. |
depression may be characterized by elevated pro-inflammatory signaling via leptin concentrations through alternate inflammatory pathways distinct to crp. |
2023-07-14 |
2023-08-14 |
human |
| Suet-Kei Wu, Wei-Jen Chen, Jane Pei-Chen Chang, Ta-Wei Guu, Ming-Che Hsin, Chih-Kun Huang, David Mischoulon, Lucile Capuron, Kuan-Pin S. Personalized Medicine of Omega-3 Fatty Acids in Depression Treatment in Obese and Metabolically Dysregulated Patients. Journal of personalized medicine. vol 13. issue 6. 2023-06-28. PMID:37373992. |
the comorbidity of depression with obesity and metabolic dysregulation is thought to be related to chronic low-grade inflammation, characterized by increased circulating levels of pro-inflammatory cytokines and c-reactive protein (crp). |
2023-06-28 |
2023-08-14 |
Not clear |
| Li Liu, Shiqiang Cheng, Xin Qi, Peilin Meng, Xuena Yang, Chuyu Pan, Yujing Chen, Huijie Zhang, Zhen Zhang, Jingxi Zhang, Chune Li, Yan Wen, Yumeng Jia, Bolun Cheng, Feng Zhan. Mitochondria-wide association study observed significant interactions of mitochondrial respiratory and the inflammatory in the development of anxiety and depression. Translational psychiatry. vol 13. issue 1. 2023-06-21. PMID:37344456. |
a mitochondria-wide association(miwas) and interaction analysis was performed to investigate the interaction effects of mitochondrial dna (mtdna)×c-reactive protein (crp) on the risks of self-reported anxiety (n = 72,476), general anxiety disorder (gad-7) scores (n = 80,853), self-reported depression (n = 80,778), patient health questionnaire (phq-9) scores (n = 80,520) in total samples, females and males, respectively, adjusting for sex, age, townsend deprivation index (tdi), education score, alcohol intake, smoking and 10 principal components. |
2023-06-21 |
2023-08-14 |
human |
| Manivel Rengasamy, Daniel Moriarity, Thomas Kraynak, Brenden Tervo-Clemmens, Rebecca Pric. Exploring the multiverse: the impact of researchers' analytic decisions on relationships between depression and inflammatory markers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-19. PMID:37336935. |
studies have begun to use multiverse analysis for well-studied relationships that have some heterogeneity in results/conclusions across studies.we examine the well-studied relationship between peripheral inflammatory markers (pims; e.g., white blood cell count (wbc) and c-reactive protein (crp)) and depression severity in the large nhanes dataset (n = 25,962). |
2023-06-19 |
2023-08-14 |
Not clear |
| Michael A Strumberger, Isabelle Häberling, Sophie Emery, Mona Albermann, Noemi Baumgartner, Naïma Bucher, Suzanne Erb, Silke Bachmann, Lars Wöckel, Ulrich Müller-Knapp, Brigitte Contin-Waldvogel, Bruno Rhiner, Susanne Walitza, Gregor Berger, Christian Cajochen, Klaus Schmec. Sleep disturbance, but not depression severity, is associated with inflammation in children and adolescents. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2023-06-16. PMID:37323001. |
we aimed to examine the association between self-rated and clinician-rated sleep disturbances and c-reactive protein (crp), an objective marker of inflammation, in pediatric depression. |
2023-06-16 |
2023-08-14 |
Not clear |
| Luca Sforzini, Annamaria Cattaneo, Clarissa Ferrari, Lorinda Turner, Nicole Mariani, Daniela Enache, Caitlin Hastings, Giulia Lombardo, Maria A Nettis, Naghmeh Nikkheslat, Courtney Worrell, Zuzanna Zajkowska, Melisa Kose, Nadia Cattane, Nicola Lopizzo, Monica Mazzelli, Linda Pointon, Philip J Cowen, Jonathan Cavanagh, Neil A Harrison, Declan Jones, Wayne C Drevets, Valeria Mondelli, Edward T Bullmore, Carmine M Pariant. Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study. Translational psychiatry. vol 13. issue 1. 2023-06-01. PMID:37264010. |
higher immune-related gene expression in major depression is independent of crp levels: results from the biodep study. |
2023-06-01 |
2023-08-14 |
Not clear |
| Ole-Jørgen Bekkevold, Jan Kristian Damås, Ben Michael Brumpton, Bjørn Olav Åsvol. The causal role of C-reactive protein and interleukin-6 on anxiety and depression symptoms and life satisfaction: Mendelian randomisation analyses in the HUNT study. Psychological medicine. 2023-05-22. PMID:37217205. |
serum levels of c-reactive protein (crp) and interleukin-6 (il-6) have been associated with anxiety and depression in cross-sectional and mendelian randomisation studies, but results regarding the effect size and direction have been mixed. |
2023-05-22 |
2023-08-14 |
Not clear |
| Ole-Jørgen Bekkevold, Jan Kristian Damås, Ben Michael Brumpton, Bjørn Olav Åsvol. The causal role of C-reactive protein and interleukin-6 on anxiety and depression symptoms and life satisfaction: Mendelian randomisation analyses in the HUNT study. Psychological medicine. 2023-05-22. PMID:37217205. |
a recent mendelian randomisation (mr) study suggested that crp may decrease and il-6 may increase anxiety and depression symptoms. |
2023-05-22 |
2023-08-14 |
Not clear |
| Angelos Halaris, Daniel Hain, Rebecca Law, Lisa Brown, David Lewis, Maria Fili. Single nucleotide polymorphisms in C-reactive protein (CRP) predict response to adjunctive celecoxib treatment of resistant bipolar depression. Brain, behavior, & immunity - health. vol 30. 2023-05-15. PMID:37181328. |
single nucleotide polymorphisms in c-reactive protein (crp) predict response to adjunctive celecoxib treatment of resistant bipolar depression. |
2023-05-15 |
2023-08-14 |
Not clear |