| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bekhbat Mandakh, Li Zhihao, Boadie W Dunlop, Michael T Treadway, Neeti D Mehta, Kate P Revill, Michael J Lucido, Hong Changdo, Ashchi Andrea, Evanthia C Wommack, David R Goldsmith, Haroon Ebrahim, Andrew H Miller, Jennifer C Felge. Sustained effects of repeated levodopa (L-DOPA) administration on reward circuitry, effort-based motivation, and anhedonia in depressed patients with higher inflammation. Brain, behavior, and immunity. 2024-12-18. PMID:39694342. |
inflammatory biomarkers like c-reactive protein (crp) are elevated in a subset of patients with depression and associated with lower functional connectivity (fc) in a ventral striatum (vs) to ventromedial prefrontal cortex (vmpfc) reward circuit and symptoms of anhedonia. |
2024-12-18 |
2024-12-21 |
Not clear |
| Lennart Seizer, Estefanía Martínez-Albert, Johanna Löchne. Nonlinear and symptom specific associations between chronotype and depression. Scientific reports. vol 14. issue 1. 2024-11-20. PMID:39562745. |
no significant effect of chronotype on levels of crp was found, suggesting that the link between chronotype and depression symptoms may not be directly mediated and appears to be stable and independent from systemic inflammation. |
2024-11-20 |
2024-11-23 |
Not clear |
| Jonas Hagenberg, Tanja M Brückl, Mira Erhart, Johannes Kopf-Beck, Maik Ködel, Ghalia Rehawi, Simone Röh-Karamihalev, Susann Sauer, Natan Yusupov, Monika Rex-Haffner, Victor I Spoormaker, Philipp Sämann, Elisabeth Binder, Janine Knauer-Arlot. Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation. Brain, behavior, and immunity. 2024-09-20. PMID:39303816. |
our initial clustering revealed four clusters, including two immune-related depression symptom clusters characterized by elevated bmi, higher depression severity and elevated levels of immune markers such as interleukin-1 receptor antagonist (il-1ra), c-reactive protein (crp) and c-c motif chemokine 2 (ccl2 or mcp-1). |
2024-09-20 |
2024-09-23 |
Not clear |
| Dana A Jarkas, Ally H Villeneuve, Ayeila Z B Daneshmend, Paul J Villeneuve, Robyn J McQuai. Sex differences in the inflammation-depression link: A systematic review and meta-analysis. Brain, behavior, and immunity. 2024-08-01. PMID:39089535. |
sex-based analyses revealed elevated levels of crp among females with depression (cohen's d = 0.19) relative to their healthy counterparts (p = 0.02), an effect not apparent among males (cohen's d = -0.01). |
2024-08-01 |
2024-08-05 |
Not clear |
| Seyed Hassan Saadat, Mohammad Javanbakht, Shima Shahya. Brain-derived neurotrophic factor and C-reactive protein (CRP) biomarkers in suicide attempter and non-attempter major depression disorder (MDD) patients. Annals of general psychiatry. vol 23. issue 1. 2024-07-22. PMID:39039500. |
brain-derived neurotrophic factor and c-reactive protein (crp) biomarkers in suicide attempter and non-attempter major depression disorder (mdd) patients. |
2024-07-22 |
2024-07-25 |
Not clear |
| b' Tihana Bagari\\xc4\\x87, Alma Mihaljevi\\xc4\\x87-Pele\\xc5\\xa1, Milena Sko\\xc4\\x8di\\xc4\\x87 Han\\xc5\\xbeek, Maja \\xc5\\xbdivkovi\\xc4\\x87, Ana Kozmar, Dunja Rogi\\xc4\\x8. Serum Levels of Zinc, Albumin, Interleukin-6 and CRP in Patients with Unipolar and Bipolar Depression: Cross Sectional Study. Current issues in molecular biology. vol 46. issue 5. 2024-05-26. PMID:38785543.' |
serum levels of zinc, albumin, interleukin-6 and crp in patients with unipolar and bipolar depression: cross sectional study. |
2024-05-26 |
2024-05-27 |
Not clear |
| b' Tihana Bagari\\xc4\\x87, Alma Mihaljevi\\xc4\\x87-Pele\\xc5\\xa1, Milena Sko\\xc4\\x8di\\xc4\\x87 Han\\xc5\\xbeek, Maja \\xc5\\xbdivkovi\\xc4\\x87, Ana Kozmar, Dunja Rogi\\xc4\\x8. Serum Levels of Zinc, Albumin, Interleukin-6 and CRP in Patients with Unipolar and Bipolar Depression: Cross Sectional Study. Current issues in molecular biology. vol 46. issue 5. 2024-05-26. PMID:38785543.' |
we found no significant differences in serum concentrations of zinc, albumin, crp, and il-6 between the groups of patients with unipolar and bipolar depression. |
2024-05-26 |
2024-05-27 |
Not clear |
| Hongqi Xiao, Yuan Cao, Paulo Lizano, Meng Li, Huan Sun, Xiaoqin Zhou, Gaoju Deng, Jiafeng Li, Tara Chand, Zhiyun Jia, Changjian Qiu, Martin Walte. Interleukin-1β moderates the relationships between middle frontal-mACC/insular connectivity and depressive symptoms in bipolar II depression. Brain, behavior, and immunity. vol 120. 2024-05-25. PMID:38777282. |
four inflammatory cytokines including interleukin (il)-6, il-1β, tumor necrosis factor (tnf)-α, and c-reactive protein (crp) and five clinical scales including hamilton depression scale (hamd), hamilton anxiety scale (hama), positive and negative syndrome scale (panss), columbia-suicide severity rating scale (c-ssrs), and childhood trauma questionnaire (ctq) were tested and assessed in bdii-d. |
2024-05-25 |
2024-05-27 |
Not clear |
| Andrea Zagaria, Valeria Fiori, Mariacarolina Vacca, Caterina Lombardo, Carmine M Pariante, Andrea Ballesi. Inflammation as a mediator between adverse childhood experiences and adult depression: A meta-analytic structural equation model. Journal of affective disorders. 2024-04-27. PMID:38677656. |
unadjusted models revealed that crp (β = 0.003, 95 % lbci 0.0002 to 0.0068), il-6 (β = 0.003, 95 % lbci 0.001 to 0.006), and composite inflammation (β = 0.009, 95 % lbci 0.004 to 0.018) significantly mediated the association between aces and adult depression. |
2024-04-27 |
2024-04-30 |
Not clear |
| Qian Gao, Jessica K Bone, Saoirse Finn, Daisy Fancour. The reciprocal associations between social deficits, social engagement, and inflammation: Longitudinal evidence comparing venous blood samples and dried blood spots and mapping the modifying role of phenotypic and genotypic depression. Brain, behavior, and immunity. 2024-03-31. PMID:38555990. |
we estimated the reciprocal associations of social deficits and social engagement with levels of c-reactive protein (crp), compared the consistency of the findings depending on the biological sampling method used, and examined the modifying role of phenotypic and genotypic depression. |
2024-03-31 |
2024-04-03 |
Not clear |
| Chiyoung Lee, Mary Whooley, Qing Yang, Daniel P Moriarit. How is inflammation biology truly associated with depression in patients with stable coronary heart disease?: Insights from the heart and Soul study. Brain, behavior, & immunity - health. vol 37. 2024-03-28. PMID:38544721. |
depression was assessed using the 9-item patient health questionnaire, while inflammation was evaluated via c-reactive protein (crp), interleukin-6 (il-6), tumor necrosis factor-alpha (tnf-α), and monocyte chemoattractant protein-1 (mcp-1) levels. |
2024-03-28 |
2024-03-30 |
Not clear |
| Richard Bränström, Mark L Hatzenbuehler, Micah R Lattanner, Nathan L Hollinsaid, Thomas W McDade, John E Pachanki. Threats to social safety and neuro-inflammatory mechanisms underlying sexual orientation disparities in depression symptom severity: A prospective cohort study of young adults. Brain, behavior, and immunity. 2024-03-28. PMID:38548185. |
to do so, we analyzed data from a prospective cohort of sexual minority and heterosexual young adults (n = 595), recruited from a nationally representative sample, that included assessments of early threats to social safety in the form of adverse childhood interpersonal events, three biomarkers of inflammation (i.e., crp, il-6, tnf-α) measured at two time points, and depression symptoms over four years. |
2024-03-28 |
2024-03-31 |
Not clear |
| Giulia Lombardo, Valeria Mondelli, Courtney Worrell, Luca Sforzini, Nicole Mariani, Naghmeh Nikkheslat, Maria A Nettis, Melisa Kose, Zuzanna Zajkowska, Annamaria Cattaneo, Linda Pointon, Lorinda Turner, Philip J Cowen, Wayne C Drevets, Jonathan Cavanagh, Neil A Harrison, Edward T Bullmore, Paola Dazzan, Carmine M Pariant. Disturbed sex hormones milieu in males and females with major depressive disorder and low-grade inflammation. Journal of affective disorders. 2024-03-17. PMID:38494137. |
here, we investigate the interplay between sex hormones and crp in the cross-sectional, observational biomarkers in depression study. |
2024-03-17 |
2024-03-20 |
Not clear |
| Naoise Mac Giollabhui, Marin M Kautz, Daniel P Moriarity, Iris K-Y Chat, Susan Murray, Lauren M Ellman, Lauren B Allo. Chronic inflammation is associated with worsening working memory performance: Preliminary evidence from a diverse, longitudinal cohort of adolescents and young adults. Psychoneuroendocrinology. vol 164. 2024-02-29. PMID:38422797. |
first, using linear regression, we tested whether individuals exhibiting inflammation (crp ≥3 mg/l) at multiple timepoints and a history of likely depression (children's depression inventory ≥19) exhibited differentially worse executive functioning, episodic memory, or psychomotor speed. |
2024-02-29 |
2024-03-03 |
human |
| Esraa A El-Sawy, Mervat M Abdul Hakim, Abeer El-Zohiery, Sherihan M Salam. Significance of inflammatory markers in primary Fibromyalgia syndrome and their relation in assessing the disease severity. The Egyptian journal of immunology. vol 31. issue 1. 2024-01-15. PMID:38224226. |
we assessed blood erythrocyte sedimentation rate (esr), neutrophil lymphocyte ratio (nlr), the mean platelet volume (mpv) and platelet distribution width (pdw), and serum levels of c-reactive protein (crp), as inflammatory markers in primary fms patients and their relationship with disease severity and depression scores. |
2024-01-15 |
2024-01-17 |
human |
| Hind Abdulla, Maher Maalouf, Herbert F Jeline. Machine Learning for the Prediction of Depression Progression from Inflammation Markers. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2023. 2023-12-12. PMID:38082683. |
logistic regression, k-nearest neighbors, support vector machine, random forest, multi-layer perceptron, and extreme gradient boosting were applied and compared to predict depression level from inflammatory marker data that included c-reactive protein (crp), interleukin (il)-6, il-1β, il-10, complement component 5a (c5a), d-dimer, monocyte chemoattractant protein (mcp)-1, and insulin-like growth factor (igf)-1. |
2023-12-12 |
2023-12-17 |
Not clear |
| Ayse Malatyali, Atami Sagna De Main, Tom Cidav, Renata Komalasari, Rui Xie, Ladda Thiamwon. Health Disparities in Cognitive Impairment and Dementia: Role of Social Strain, Depression, and C-Reactive Protein. Gerontology & geriatric medicine. vol 9. 2023-11-30. PMID:38035262. |
measures included the 27-point hrs cognition scale, social strain scale, center for epidemiological studies depression scale, and dried-blood crp levels. |
2023-11-30 |
2023-12-10 |
human |
| Joshua J Schwartz, Chloe Roske, Qi Liu, Russel H Tobe, Benjamin A Ely, Vilma Gabba. C-reactive protein does not predict future depression onset in adolescents: preliminary findings from a longitudinal study. medRxiv : the preprint server for health sciences. 2023-11-14. PMID:37961448. |
elevated c-reactive protein (crp), an indicator of non-specific inflammation commonly utilized in clinical practice, has been associated with depression in adults. |
2023-11-14 |
2023-11-20 |
Not clear |
| Joshua J Schwartz, Chloe Roske, Qi Liu, Russel H Tobe, Benjamin A Ely, Vilma Gabba. C-reactive protein does not predict future depression onset in adolescents: preliminary findings from a longitudinal study. medRxiv : the preprint server for health sciences. 2023-11-14. PMID:37961448. |
we hypothesized that the distinct crp findings in adolescent vs. adult depression may be due to chronicity, with neuroinflammatory effects on psychiatric disorders gradually accumulating over time. |
2023-11-14 |
2023-11-20 |
Not clear |
| Joshua J Schwartz, Chloe Roske, Qi Liu, Russel H Tobe, Benjamin A Ely, Vilma Gabba. C-reactive protein does not predict future depression onset in adolescents: preliminary findings from a longitudinal study. medRxiv : the preprint server for health sciences. 2023-11-14. PMID:37961448. |
here, we conducted a longitudinal study to evaluate if crp levels predicted future onset or progression of depression in adolescents. |
2023-11-14 |
2023-11-20 |
Not clear |