| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shawn Hayley, Darcy Litteljoh. Neuroplasticity and the next wave of antidepressant strategies. Frontiers in cellular neuroscience. vol 7. 2014-03-10. PMID:24312008. |
we posit that psychological and immune stressors can interact upon a vulnerable genetic background to promote depression by disturbing bdnf and neuroplastic processes. |
2014-03-10 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Thomas M Olino, Sara J Bufferd, Anna Miller, Lea R Dougherty, Haroon I Sheikh, Shiva M Singh, Daniel N Klei. The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood. Development and psychopathology. vol 25. issue 3. 2014-03-06. PMID:23880378. |
preliminary work indicates that cognitive vulnerability to depression may be associated with variants of the serotonin transporter promoter polymorphism (5-httlpr) and the valine to methionine at position 66 (val66met) polymorphism of the brain-derived neurotrophic factor (bdnf) gene; however, existing reports come from small samples. |
2014-03-06 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Thomas M Olino, Sara J Bufferd, Anna Miller, Lea R Dougherty, Haroon I Sheikh, Shiva M Singh, Daniel N Klei. The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood. Development and psychopathology. vol 25. issue 3. 2014-03-06. PMID:23880378. |
the bdnf val66met polymorphism had no main effect but was moderated by maternal depression, such that children with a bdnf methionine allele had a heightened memory for negative self-descriptive traits when mothers had experienced depression during children's lifetimes; in contrast, children with a methionine allele had low recall of negative traits when mothers had no depression history. |
2014-03-06 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Thomas M Olino, Sara J Bufferd, Anna Miller, Lea R Dougherty, Haroon I Sheikh, Shiva M Singh, Daniel N Klei. The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: associations with cognitive vulnerability to depression in childhood. Development and psychopathology. vol 25. issue 3. 2014-03-06. PMID:23880378. |
the findings provide further support for the notion that the 5-httlpr is associated with cognitive markers of depression vulnerability and that the bdnf methionine allele moderates children's sensitivity to contextual factors. |
2014-03-06 |
2023-08-12 |
Not clear |
| Richard Musil, Peter Zill, Florian Seemüller, Brigitta Bondy, Michael Obermeier, Ilja Spellmann, Wolfram Bender, Mazda Adli, Isabella Heuser, Joachim Zeiler, Wolfgang Gaebel, Wolfgang Maier, Marcella Rietschel, Dan Rujescu, Rebecca Schennach, Hans-Jürgen Möller, Michael Riede. No influence of brain-derived neurotrophic factor (BDNF) polymorphisms on treatment response in a naturalistic sample of patients with major depression. European archives of psychiatry and clinical neuroscience. vol 263. issue 5. 2014-02-28. PMID:22965830. |
no influence of brain-derived neurotrophic factor (bdnf) polymorphisms on treatment response in a naturalistic sample of patients with major depression. |
2014-02-28 |
2023-08-12 |
Not clear |
| Richard Musil, Peter Zill, Florian Seemüller, Brigitta Bondy, Michael Obermeier, Ilja Spellmann, Wolfram Bender, Mazda Adli, Isabella Heuser, Joachim Zeiler, Wolfgang Gaebel, Wolfgang Maier, Marcella Rietschel, Dan Rujescu, Rebecca Schennach, Hans-Jürgen Möller, Michael Riede. No influence of brain-derived neurotrophic factor (BDNF) polymorphisms on treatment response in a naturalistic sample of patients with major depression. European archives of psychiatry and clinical neuroscience. vol 263. issue 5. 2014-02-28. PMID:22965830. |
recent post hoc analyses indicated a potential association of three polymorphisms in the bdnf gene with worse treatment outcome in patients with the subtype of melancholic depression. |
2014-02-28 |
2023-08-12 |
Not clear |
| Jon Adlam, Rashid Zama. The role of BDNF and memory in major depressive disorder. Psychiatria Danubina. vol 25 Suppl 2. 2014-02-25. PMID:23995212. |
the role of bdnf in depression and major depressive disorder (mdd) has been extensively investigated in the literature. |
2014-02-25 |
2023-08-12 |
Not clear |
| Jon Adlam, Rashid Zama. The role of BDNF and memory in major depressive disorder. Psychiatria Danubina. vol 25 Suppl 2. 2014-02-25. PMID:23995212. |
a summary of relevant papers, including a number of independent literature reviews, is presented, and the possibility that alteration in bdnf causes depression by altering memory is analysed and criticised in the context of consistency with cognitive models of depression. |
2014-02-25 |
2023-08-12 |
Not clear |
| Undine E Lang, Stefan Borgward. Molecular mechanisms of depression: perspectives on new treatment strategies. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 31. issue 6. 2014-02-18. PMID:23735822. |
the neurodegenerative hypothesis of depression explains decreased hippocampal volumes in depressed patients and changes of neurotrophic support by bdnf, erythropoietin, gdnf, fgf-2, nt3, ngf and growth hormone. |
2014-02-18 |
2023-08-12 |
Not clear |
| I-Te Lee, Chia-Po Fu, Wen-Jane Lee, Kae-Woei Liang, Shih-Yi Lin, Chu-Jen Wan, Wayne Huey-Herng She. Brain-derived neurotrophic factor, but not body weight, correlated with a reduction in depression scale scores in men with metabolic syndrome: a prospective weight-reduction study. Diabetology & metabolic syndrome. vol 6. issue 1. 2014-02-17. PMID:24524285. |
deficiency of brain-derived neurotrophic factor (bdnf) is involved in the mechanism of depression. |
2014-02-17 |
2023-08-12 |
Not clear |
| Katharina Domschk. Clinical and molecular genetics of psychotic depression. Schizophrenia bulletin. vol 39. issue 4. 2014-02-14. PMID:23512949. |
molecular genetic studies point to potential risk loci of psychotic depression shared with schizoaffective disorder (1q42, 22q11, 19p13), depression, bipolar disorder, and schizophrenia (6p, 8p22, 10p13-12, 10p14, 13q13-14, 13q32, 18p, 22q11-13) and several vulnerability genes possibly contributing to an increased risk of psychotic symptoms in depression (eg, bdnf, dbh, dtnbp1, drd2, drd4, gsk-3beta, mao-a). |
2014-02-14 |
2023-08-12 |
Not clear |
| Gerald J Haeffel, Maria Eastman, Elena L Grigorenk. Using a cognitive endophenotype to identify risk genes for depression. Neuroscience letters. vol 510. issue 1. 2014-01-31. PMID:22240101. |
we investigated two possible genetic contributors to individual differences in cognitive vulnerability (and, in turn, depression): the bdnf gene and the comt gene. |
2014-01-31 |
2023-08-12 |
human |
| Gerald J Haeffel, Maria Eastman, Elena L Grigorenk. Using a cognitive endophenotype to identify risk genes for depression. Neuroscience letters. vol 510. issue 1. 2014-01-31. PMID:22240101. |
results support the use of the cognitive vulnerability factor featured in hopelessness theory as an endophenotype associated with depression as well as the role of the bdnf gene in a cognitive subtype of depression. |
2014-01-31 |
2023-08-12 |
human |
| Richard Musil, Peter Zill, Florian Seemüller, Brigitta Bondy, Sebastian Meyer, Ilja Spellmann, Wolfram Bender, Mazda Adli, Isabella Heuser, Robert Fisher, Wolfgang Gaebel, Wolfgang Maier, Marcella Rietschel, Dan Rujescu, Rebecca Schennach, Hans-Jürgen Möller, Michael Riede. Genetics of emergent suicidality during antidepressive treatment--data from a naturalistic study on a large sample of inpatients with a major depressive episode. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 7. 2014-01-23. PMID:23063133. |
common polymorphisms involved in the tryptophan hydroxylase 1 (tph1) and 2 (tph2), serotonin transporter, monoamine oxidase a (maoa) and brain-derived neurotrophic factor (bdnf) were investigated in a naturalistic inpatient study of the german research network on depression. |
2014-01-23 |
2023-08-12 |
Not clear |
| S B Seredenin, T A Voronina, T A Gudasheva, T L Garibova, G M Molodavkin, S A Litvinova, E A Elizarova, V I Posev. Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF. Acta naturae. vol 5. issue 4. 2014-01-23. PMID:24455189. |
a large amount of clinical and experimental data suggest the involvement of neurotrophins, in particular the brain-derived neurotrophic factor (bdnf), in depression pathogenesis. |
2014-01-23 |
2023-08-12 |
mouse |
| S B Seredenin, T A Voronina, T A Gudasheva, T L Garibova, G M Molodavkin, S A Litvinova, E A Elizarova, V I Posev. Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF. Acta naturae. vol 5. issue 4. 2014-01-23. PMID:24455189. |
the obtained evidence supports the hypothesis on the involvement of bdnf in the pathogenesis of various depression conditions, thus opening prospects for searching for new original antidepressants. |
2014-01-23 |
2023-08-12 |
mouse |
| Francis E Lotrich, Salwa Albusaysi, Robert E Ferrel. Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 6. 2014-01-21. PMID:23303061. |
depression has been associated with inflammation, and inflammation may both influence and interact with growth factors such as brain-derived neurotrophic factor (bdnf). |
2014-01-21 |
2023-08-12 |
Not clear |
| Francis E Lotrich, Salwa Albusaysi, Robert E Ferrel. Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 6. 2014-01-21. PMID:23303061. |
both the functional val66met bdnf polymorphism (rs6265) and bdnf levels have been associated with depression. |
2014-01-21 |
2023-08-12 |
Not clear |
| Francis E Lotrich, Salwa Albusaysi, Robert E Ferrel. Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 6. 2014-01-21. PMID:23303061. |
it is thus plausible that decreased bdnf could mediate and/or moderate cytokine-induced depression. |
2014-01-21 |
2023-08-12 |
Not clear |
| Francis E Lotrich, Salwa Albusaysi, Robert E Ferrel. Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-α treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 6. 2014-01-21. PMID:23303061. |
we therefore prospectively employed the beck depression inventory-ii (bdi-ii), the hospital anxiety and depression scale (hads), and the montgomery-asberg depression rating scale (madrs) in 124 initially euthymic patients during treatment with interferon-alpha (ifn-α), assessing serum bdnf and rs6265. |
2014-01-21 |
2023-08-12 |
Not clear |