| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A S Zagam. Cortical spreading depression and the migraine aura. Internal medicine journal. vol 40. issue 11. 2011-09-30. PMID:21108719. |
cortical spreading depression and the migraine aura. |
2011-09-30 |
2023-08-12 |
Not clear |
| Yelena Y Grinberg, John G Milton, Richard P Krai. Spreading depression sends microglia on Lévy flights. PloS one. vol 6. issue 4. 2011-08-23. PMID:21541289. |
spreading depression (sd) is thought to cause migraine aura, and perhaps migraine, and includes a transient loss of synaptic activity preceded and followed by increased neuronal excitability. |
2011-08-23 |
2023-08-12 |
rat |
| Ulrike Hoffmann, Ergin Dileköz, Chiho Kudo, Cenk Ayat. Oxcarbazepine does not suppress cortical spreading depression. Cephalalgia : an international journal of headache. vol 31. issue 5. 2011-08-01. PMID:21059627. |
cortical spreading depression is the electrophysiological substrate of migraine aura, and may trigger headache. |
2011-08-01 |
2023-08-12 |
Not clear |
| Angelita Tottene, Andrea Urbani, Daniela Pietrobo. Role of different voltage-gated Ca2+ channels in cortical spreading depression: specific requirement of P/Q-type Ca2+ channels. Channels (Austin, Tex.). vol 5. issue 2. 2011-07-15. PMID:21150292. |
knockin (ki) mice carrying fhm1 mutations show increased neuronal p/q-type current and facilitation of induction and propagation of cortical spreading depression (csd), the phenomenon that underlies migraine aura and may activate migraine headache mechanisms. |
2011-07-15 |
2023-08-12 |
mouse |
| Xichun Zhang, Dan Levy, Vanessa Kainz, Rodrigo Noseda, Moshe Jakubowski, Rami Burstei. Activation of central trigeminovascular neurons by cortical spreading depression. Annals of neurology. vol 69. issue 5. 2011-06-24. PMID:21416489. |
cortical spreading depression (csd) has long been implicated in migraine attacks that begin with visual aura. |
2011-06-24 |
2023-08-12 |
Not clear |
| Katharina Eikermann-Haerter, Izumi Yuzawa, Tao Qin, Yumei Wang, Kwangyeol Baek, Young Ro Kim, Ulrike Hoffmann, Ergin Dilekoz, Christian Waeber, Michel D Ferrari, Arn M J M van den Maagdenberg, Michael A Moskowitz, Cenk Ayat. Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490217. |
familial hemiplegic migraine knock-in mice expressing the s218l or r192q mutation are highly susceptible to cortical spreading depression, the electrophysiological surrogate for migraine aura, and develop severe and prolonged motor deficits after spreading depression. |
2011-06-13 |
2023-08-12 |
mouse |
| Katharina Eikermann-Haerter, Izumi Yuzawa, Ergin Dilekoz, Anne Joutel, Michael A Moskowitz, Cenk Ayat. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression. Annals of neurology. vol 69. issue 2. 2011-05-11. PMID:21387384. |
here, we report that cortical spreading depression (csd), the electrophysiological substrate of migraine aura, is enhanced in mice expressing a vascular notch 3 cadasil mutation (r90c) or a notch 3 knockout mutation. |
2011-05-11 |
2023-08-12 |
mouse |
| Katharina Eikermann-Haerter, Izumi Yuzawa, Ergin Dilekoz, Anne Joutel, Michael A Moskowitz, Cenk Ayat. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression. Annals of neurology. vol 69. issue 2. 2011-05-11. PMID:21387384. |
our results link vascular smooth muscle notch 3 mutations to enhanced spreading depression susceptibility, implicating the neurovascular unit in the development of migraine aura. |
2011-05-11 |
2023-08-12 |
mouse |
| Jonas I Addae, Nakisha Ali, Trevor W Ston. Effects of AMPA and clomethiazole on spreading depression cycles in the rat neocortex in vivo. European journal of pharmacology. vol 653. issue 1-3. 2011-05-02. PMID:21147095. |
activation of nmda receptors is involved in the pathogenesis of cortical spreading depression (csd) which has been implicated in the pathogenesis of migraine aura and neuronal damage from peri-infarct depolarizations. |
2011-05-02 |
2023-08-12 |
rat |
| Oliver Summ, Philip R Holland, Simon Akerman, Peter J Goadsb. TRPV1 receptor blockade is ineffective in different in vivo models of migraine. Cephalalgia : an international journal of headache. vol 31. issue 2. 2011-04-28. PMID:20974587. |
due to a possible role of trpv1 receptors in cortical spreading depression (csd), an experimental phenomenon sharing many features with migraine aura, we also utilized a model of mechanically induced csd. |
2011-04-28 |
2023-08-12 |
rat |
| P R Holland, S Akerman, P J Goadsb. Cortical spreading depression-associated cerebral blood flow changes induced by mechanical stimulation are modulated by AMPA and GABA receptors. Cephalalgia : an international journal of headache. vol 30. issue 5. 2011-01-25. PMID:20511201. |
the underlying mechanism behind the aura is generally considered to be a form of cortical spreading depression (csd). |
2011-01-25 |
2023-08-12 |
rat |
| E A Bates, T Nikai, K C Brennan, Y-H Fu, A C Charles, A I Basbaum, L J Ptácek, A H Ah. Sumatriptan alleviates nitroglycerin-induced mechanical and thermal allodynia in mice. Cephalalgia : an international journal of headache. vol 30. issue 2. 2011-01-24. PMID:19489890. |
we also tested whether ntg reduces the threshold for cortical spreading depression (csd), an event considered to be the physiological substrate of the migraine aura. |
2011-01-24 |
2023-08-12 |
mouse |
| P C Tfelt-Hanse. History of migraine with aura and cortical spreading depression from 1941 and onwards. Cephalalgia : an international journal of headache. vol 30. issue 7. 2010-11-16. PMID:19740119. |
leão described cortical spreading depression (csd) in rabbits in 1944 and noticed its similarity to the migraine aura. |
2010-11-16 |
2023-08-12 |
mouse |
| Ulrike Hoffmann, Ergin Dileköz, Chiho Kudo, Cenk Ayat. Gabapentin suppresses cortical spreading depression susceptibility. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 30. issue 9. 2010-10-19. PMID:20588320. |
cortical spreading depression (csd) is an intense depolarization wave implicated in the pathophysiology of brain injury states and migraine aura. |
2010-10-19 |
2023-08-12 |
rat |
| Jakob Møller Hanse. Familial hemiplegic migraine. Danish medical bulletin. vol 57. issue 9. 2010-10-08. PMID:20816023. |
abnormal cortical excitability due to dysfunctional ion-channels might facilitate cortical spreading depression (csd) and thereby migraine aura and migraine headache. |
2010-10-08 |
2023-08-12 |
Not clear |
| Daniela Pietrobo. Insights into migraine mechanisms and CaV2.1 calcium channel function from mouse models of familial hemiplegic migraine. The Journal of physiology. vol 588. issue Pt 11. 2010-08-27. PMID:20194127. |
the fhm1 knockin mice show allele dosage-dependent gain-of-function of neuronal p/q-type ca2+ current, reflecting activation of mutant channels at lower voltages, and allele dosage- and sex-dependent facilitation of induction and propagation of cortical spreading depression (csd), the phenomenon that underlies migraine aura. |
2010-08-27 |
2023-08-12 |
mouse |
| Katharina Eikermann-Haerter, Cenk Ayat. Cortical spreading depression and migraine. Current neurology and neuroscience reports. vol 10. issue 3. 2010-07-22. PMID:20425031. |
imaging studies in migraineurs demonstrated hemodynamic changes consistent with cortical spreading depression during aura, whereas recent animal studies helped unravel pathophysiologic aspects such as the triggering mechanisms, genetic and hormonal modulation, and potential therapeutic targets. |
2010-07-22 |
2023-08-12 |
Not clear |
| Xichun Zhang, Dan Levy, Rodrigo Noseda, Vanessa Kainz, Moshe Jakubowski, Rami Burstei. Activation of meningeal nociceptors by cortical spreading depression: implications for migraine with aura. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 26. 2010-07-22. PMID:20592202. |
the purpose of this study was to determine whether cortical spreading depression (csd)--an event believed to underlie visual aura--can give rise to activation of nociceptors that innervate the meninges--an event believed to set off migraine headache. |
2010-07-22 |
2023-08-12 |
rat |
| H Haghir, S Kovac, E-J Speckmann, K Zilles, A Gorj. Patterns of neurotransmitter receptor distributions following cortical spreading depression. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19665048. |
spreading depression (sd), a self-propagating depolarization of neurons and glia, is believed to play a role in different neurological disorders including migraine aura and acute brain ischaemia. |
2010-02-12 |
2023-08-12 |
rat |
| Junichi Hamad. [Use of antiepileptic drugs for the preventive treatment of migraine]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 10. 2010-01-19. PMID:19882937. |
it has been found that cortical spreading depression is involved in the pathophysiological mechanism of epilepsy, in addition to the generation of migraine aura. |
2010-01-19 |
2023-08-12 |
Not clear |