| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Frank Richter, Andrea Ebersberger, Hans-Georg Schaibl. Blockade of voltage-gated calcium channels in rat inhibits repetitive cortical spreading depression. Neuroscience letters. vol 334. issue 2. 2003-01-24. PMID:12435487. |
blockers of l-, n-, and p/q-type voltage-gated calcium channels (vgccs) were topically applied to the cortical surface of anaesthetized adult rats to study their role in cortical spreading depression (csd), a correlate of the migraine aura. |
2003-01-24 |
2023-08-12 |
rat |
| Chiaki Yokota, Yuji Kuge, Yasuhiro Hasegawa, Masafumi Tagaya, Takeo Abumiya, Norimasa Ejima, Nagara Tamaki, Takenori Yamaguchi, Kazuo Minemats. Unique profile of spreading depression in a primate model. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 22. issue 7. 2002-08-09. PMID:12142568. |
spreading depression (sd) is considered to play a role in pathologic conditions of humans such as in the evolution of ischemic brain injury and migraine aura. |
2002-08-09 |
2023-08-12 |
monkey |
| Rajani Choudhuri, Lisa Cui, Chi Yong, Susan Bowyer, Robert M Klein, K M A Welch, Nancy E J Berma. Cortical spreading depression and gene regulation: relevance to migraine. Annals of neurology. vol 51. issue 4. 2002-04-18. PMID:11921056. |
cortical spreading depression (csd) may be the underlying mechanism of migraine aura. |
2002-04-18 |
2023-08-12 |
mouse |
| Jens P Dreier, Jörg Kleeberg, Gabor Petzold, Josef Priller, Olaf Windmüller, Hans-Dieter Orzechowski, Ute Lindauer, Uwe Heinemann, Karl M Einhäupl, Ulrich Dirnag. Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? Brain : a journal of neurology. vol 125. issue Pt 1. 2002-03-01. PMID:11834596. |
endothelin-1 potently induces leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? |
2002-03-01 |
2023-08-12 |
rat |
| Jens P Dreier, Jörg Kleeberg, Gabor Petzold, Josef Priller, Olaf Windmüller, Hans-Dieter Orzechowski, Ute Lindauer, Uwe Heinemann, Karl M Einhäupl, Ulrich Dirnag. Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura? Brain : a journal of neurology. vol 125. issue Pt 1. 2002-03-01. PMID:11834596. |
according to the 'neuronal' theory, cortical spreading depression (csd) is the pathophysiological correlate of migrainous aura. |
2002-03-01 |
2023-08-12 |
rat |
| D P Bradley, M I Smith, C Netsiri, J M Smith, K H Bockhorst, L D Hall, C L Huang, R A Leslie, A A Parsons, M F Jame. Diffusion-weighted MRI used to detect in vivo modulation of cortical spreading depression: comparison of sumatriptan and tonabersat. Experimental neurology. vol 172. issue 2. 2002-02-06. PMID:11716558. |
spreading cortical depolarization and depression of electroencephalographic activity (sd) may underlie the aura and spreading neurovascular events of migraine. |
2002-02-06 |
2023-08-12 |
human |
| A Gorji, D Scheller, H Straub, F Tegtmeier, R Köhling, J M Höhling, I Tuxhorn, A Ebner, P Wolf, H Werner Panneck, F Oppel, E J Speckman. Spreading depression in human neocortical slices. Brain research. vol 906. issue 1-2. 2001-09-13. PMID:11430863. |
cortical spreading depression (csd) occurrence has been suggested to be associated with seizures, migraine aura, head injury and brain ischemia-infarction. |
2001-09-13 |
2023-08-12 |
human |
| M F James, J M Smith, S J Boniface, C L Huang, R A Lesli. Cortical spreading depression and migraine: new insights from imaging? Trends in neurosciences. vol 24. issue 5. 2001-07-19. PMID:11311378. |
the possibility that spreading depression (sd) of cortical activity, a phenomenon observed in all vertebrates, causes the aura of migraine remains an open question in spite of nearly half a century of investigation. |
2001-07-19 |
2023-08-12 |
Not clear |
| N Hadjikhani, M Sanchez Del Rio, O Wu, D Schwartz, D Bakker, B Fischl, K K Kwong, F M Cutrer, B R Rosen, R B Tootell, A G Sorensen, M A Moskowit. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 8. 2001-05-10. PMID:11287655. |
cortical spreading depression (csd) has been suggested to underlie migraine visual aura. |
2001-05-10 |
2023-08-12 |
human |
| U Reuter, M Sanchez del Rio, M A Moskowit. Experimental models of migraine. Functional neurology. vol 15 Suppl 3. 2001-03-22. PMID:11200808. |
in addition, we briefly summarize the results of cortical spreading depression studies, as they relate to the human migraine aura. |
2001-03-22 |
2023-08-12 |
human |
| J C Baro. [The pathophysiology of migraine: insights from functional neuroimaging]. Revue neurologique. vol 156 Suppl 4. 2001-02-08. PMID:11139743. |
the migraine aura is characterized by the occurrence of an hypoperfusion of moderate intensity which is peculiar by its initial appearance in the posterior cortex and its anterior spread at a speed of about 2 to 3mm per minute, congruent with the migrainous march of neurologic deficit and reminiscent of the phenomenon of cortical spreading depression described in the laboratory animal after various neuronal aggressions. |
2001-02-08 |
2023-08-12 |
human |
| P J Goadsb. Migraine, aura, and cortical spreading depression: why are we still talking about it? Annals of neurology. vol 49. issue 1. 2001-02-08. PMID:11198295. |
migraine, aura, and cortical spreading depression: why are we still talking about it? |
2001-02-08 |
2023-08-12 |
Not clear |
| A Ebersberger, H G Schaible, B Averbeck, F Richte. Is there a correlation between spreading depression, neurogenic inflammation, and nociception that might cause migraine headache? Annals of neurology. vol 49. issue 1. 2001-02-08. PMID:11198299. |
the time course of propagation of scotoma and blood flow changes during migraine aura parallels the phenomenon of cortical spreading depression (csd). |
2001-02-08 |
2023-08-12 |
rat |
| G Mic. [Physiopathology of the migraine attack and mechanisms of action of anti-migraine agents: recent findings in animals]. Pathologie-biologie. vol 48. issue 7. 2000-12-04. PMID:11072637. |
a neurovascular cortical spreading depression could be one of the mechanisms involved in aura formation, but its association with headache is enigmatic, and the implication of hypoxia in its etiopathogenesis remains controversial. |
2000-12-04 |
2023-08-12 |
Not clear |
| H Kaube, J Herzog, T Käufer, M Dichgans, H C Diene. Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine. Neurology. vol 55. issue 1. 2000-08-07. PMID:10891926. |
migraine aura is probably caused by cortical-spreading depression. |
2000-08-07 |
2023-08-12 |
Not clear |
| Y Cao, K M Welch, S Aurora, E M Vikingsta. Functional MRI-BOLD of visually triggered headache in patients with migraine. Archives of neurology. vol 56. issue 5. 1999-05-27. PMID:10328249. |
spreading depression of leao has been hypothesized as the basis for the visual aura of the migraine attack, supported by cerebral blood flow measurements of spreading hypoperfusion. |
1999-05-27 |
2023-08-12 |
Not clear |
| K Shibata, M Osawa, M Iwat. Pattern reversal visual evoked potentials in migraine with aura and migraine aura without headache. Cephalalgia : an international journal of headache. vol 18. issue 6. 1998-11-10. PMID:9731935. |
we conclude from our pvep findings that cortical spreading depression remains the most likely explanation for the migraine visual aura. |
1998-11-10 |
2023-08-12 |
human |
| K M Welc. Pathogenesis of migraine. Seminars in neurology. vol 17. issue 4. 1998-03-26. PMID:9474713. |
models of aura mechanisms include transient cerebral ischemia and spreading depression. |
1998-03-26 |
2023-08-12 |
Not clear |
| D L Taylor, J Urenjak, E Zilkha, T P Obrenovitc. Effects of probenecid on the elicitation of spreading depression in the rat striatum. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295200. |
spreading depression (sd) is a wave of cellular depolarization which contributes to neuronal damage in experimental focal ischaemia, and may also underlie the migraine aura. |
1997-10-23 |
2023-08-12 |
rat |
| P Osten, S Hrabetova, T C Sackto. Differential downregulation of protein kinase C isoforms in spreading depression. Neuroscience letters. vol 221. issue 1. 1997-04-09. PMID:9014175. |
spreading depression (sd) is a propagating depolarization of populations of neurons induced by intense electrical, chemical, or mechanical stimulation, which has been proposed to be an important mechanism in the aura of migraine. |
1997-04-09 |
2023-08-12 |
Not clear |