Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Cecile Spielewoy, Athina Marko. Withdrawal from chronic phencyclidine treatment induces long-lasting depression in brain reward function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700700. |
withdrawal from chronic phencyclidine treatment induces long-lasting depression in brain reward function. |
2003-08-04 |
2023-08-12 |
rat |
Cecile Spielewoy, Athina Marko. Withdrawal from chronic phencyclidine treatment induces long-lasting depression in brain reward function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700700. |
specifically, withdrawal from 15 or 20 mg/kg/day pcp induced a depression in brain reward function that lasted for the entire month of observation. |
2003-08-04 |
2023-08-12 |
rat |
Cecile Spielewoy, Athina Marko. Withdrawal from chronic phencyclidine treatment induces long-lasting depression in brain reward function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700700. |
these results indicate that prolonged continuous administration of high pcp doses facilitates brain stimulation reward, while withdrawal from acute high pcp doses or chronic pcp treatment results in a protracted depression of brain reward function that may be analogous to the dysphoric and anhedonic symptoms observed in pcp dependence, depression, and schizophrenia. |
2003-08-04 |
2023-08-12 |
rat |
Y Ono, J Ando, N Onoda, K Yoshimura, T Momose, M Hirano, S Kanb. Dimensions of temperament as vulnerability factors in depression. Molecular psychiatry. vol 7. issue 9. 2003-04-30. PMID:12399947. |
dimensions of temperament associated with novelty seeking, harm avoidance, reward dependence, and persistence were measured by using the temperament and character instruments developed by cloninger, and depressive symptoms were measured using the hospital anxiety and depression scale. |
2003-04-30 |
2023-08-12 |
Not clear |
A Pelissolo, E Corrubl. [Personality factors in depressive disorders: contribution of the psychobiologic model developed by Cloninger]. L'Encephale. vol 28. issue 4. 2002-12-19. PMID:12232546. |
other temperament dimensions, novelty seeking and reward dependence, are not consistently associated with depression characteristics nor affected by state effects, but self-directedness character dimension is often low when compared to subjects without depressive disorders, reflecting maladaptive personalities frequently associated to depressive disorders. |
2002-12-19 |
2023-08-12 |
human |
Laura Cardenas, Lescia K Tremblay, Claudio A Naranjo, Nathan Herrmann, Martin Zack, Usoa E Bust. Brain reward system activity in major depression and comorbid nicotine dependence. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183688. |
brain reward system activity in major depression and comorbid nicotine dependence. |
2002-09-18 |
2023-08-12 |
human |
S Genedani, S Saltini, A Benelli, M Filaferro, A Bertolin. Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression. Neuroreport. vol 12. issue 18. 2002-03-18. PMID:11742215. |
these results may suggest (i) a role for brain polyamines in depression and in reward processes, and (ii) that the antidepressant effect of same may be due, at least in part, to a normalization of putrescine levels in the nucleus accumbens septi. |
2002-03-18 |
2023-08-12 |
rat |
C A Naranjo, L K Tremblay, U E Bust. The role of the brain reward system in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 4. 2001-10-25. PMID:11383978. |
the role of the brain reward system in depression. |
2001-10-25 |
2023-08-12 |
human |
J C Von Frijtag, L G Reijmers, J E Van der Harst, I E Leus, R Van den Bos, B M Spruij. Defeat followed by individual housing results in long-term impaired reward- and cognition-related behaviours in rats. Behavioural brain research. vol 117. issue 1-2. 2001-02-08. PMID:11099767. |
the impaired capability to anticipate for a reward was discussed in relation to anhedonia, an important symptom of human depression. |
2001-02-08 |
2023-08-12 |
human |
D Lin, G F Koob, A Marko. Differential effects of withdrawal from chronic amphetamine or fluoxetine administration on brain stimulation reward in the rat--interactions between the two drugs. Psychopharmacology. vol 145. issue 3. 1999-10-18. PMID:10494577. |
withdrawal from chronic amphetamine administration is characterized by deficits in reward that resemble some symptoms of depression. |
1999-10-18 |
2023-08-12 |
rat |
P W Gold, G P Chrouso. The endocrinology of melancholic and atypical depression: relation to neurocircuitry and somatic consequences. Proceedings of the Association of American Physicians. vol 111. issue 1. 1999-02-16. PMID:9893154. |
in addition, recent data reveal important bidirectional interactions between stress-system hormonal factors in depression and neural substrates implicated in many discrete behavioral alterations in depression (e.g., the medial prefrontal cortex, important in shifting affect based on internal and external cues, the mesolimbic dopaminergic reward system, and the amygdala fear system). |
1999-02-16 |
2023-08-12 |
Not clear |
R B Wilkinso. Interactions between self and external reinforcement in predicting depressive symptoms. Behaviour research and therapy. vol 35. issue 4. 1997-06-24. PMID:9134782. |
this paper examines the relationship between dispositional rates of self-reinforcement, as assessed by the frequency of self-reinforcement questionnaire (heiby, 1982, behaviour research and therapy, 20, 397-401), external sources of reward and punishment, extraversion, neuroticism, and depression. |
1997-06-24 |
2023-08-12 |
Not clear |
D H Overstreet, A H Rezvani, D J Knapp, F T Crews, D S Janowsk. Further selection of rat lines differing in 5-HT-1A receptor sensitivity: behavioral and functional correlates. Psychiatric genetics. vol 6. issue 3. 1997-02-18. PMID:8902886. |
these findings clearly show that consistent behavioral differences do occur in the 8-oh-dpat-selected lines of rats, but only for behaviors related to possible depression or reward, not anxiety. |
1997-02-18 |
2023-08-12 |
rat |
S A Josselyn, V P Franco, F J Vaccarin. Devazepide, a CCKA receptor antagonist, impairs the acquisition of conditioned reward and conditioned activity. Psychopharmacology. vol 123. issue 2. 1996-12-03. PMID:8741936. |
two novel levers were presented to drug-free animals in a test session; depression of the conditioned reward (cr) lever produced a light-tone stimulus previously paired with food availability while depression of the non-cr lever produced no programmed consequence. |
1996-12-03 |
2023-08-12 |
rat |
H GLEITMAN, F STEINMA. DEPRESSION EFFECT AS A FUNCTION OF RETENTION INTERVAL BEFORE AND AFTER SHIFT IN REWARD MAGNITUDE. Journal of comparative and physiological psychology. vol 57. 1996-12-01. PMID:14125081. |
depression effect as a function of retention interval before and after shift in reward magnitude. |
1996-12-01 |
2023-08-12 |
Not clear |
A J Chien, D L Dunne. The Tridimensional Personality Questionnaire in depression: state versus trait issues. Journal of psychiatric research. vol 30. issue 1. 1996-10-30. PMID:8736463. |
while novelty seeking and reward dependence remain relatively independent of mood, harm avoidance appears to be a measure which is elevated during depressive states and which changes with improvement of depression. |
1996-10-30 |
2023-08-12 |
human |
K Matthews, L S Wilkinson, T W Robbin. Repeated maternal separation of preweanling rats attenuates behavioral responses to primary and conditioned incentives in adulthood. Physiology & behavior. vol 59. issue 1. 1996-10-24. PMID:8848498. |
these data are discussed with respect to the putative involvement of ventral striatal dopamine systems in reward mechanisms and the potential utility of early maternal separation as an animal model of depression. |
1996-10-24 |
2023-08-12 |
rat |
E W Freeman, E Schweizer, K Rickel. Personality factors in women with premenstrual syndrome. Psychosomatic medicine. vol 57. issue 5. 1996-02-20. PMID:8552736. |
as hypothesized, the ha scores were significantly higher in the comparison groups diagnosed with major depression; the ns and reward dependence (rd) dimensions did not differ between the pms and mdd groups. |
1996-02-20 |
2023-08-12 |
human |
A A Grac. The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug and alcohol dependence. vol 37. issue 2. 1995-06-26. PMID:7758401. |
stimulants are known to elicit locomotion and stimulate reward sites by releasing dopamine from terminals in the nucleus accumbens, which is followed by a rebound depression. |
1995-06-26 |
2023-08-12 |
Not clear |
D Goldber. A bio-social model for common mental disorders. Acta psychiatrica Scandinavica. Supplementum. vol 385. 1995-06-08. PMID:7740974. |
another reason why the symptom dimensions overlap is that depression and anxiety relate to reward and punishment systems respectively, and these systems are necessarily reciprocally related to one another. |
1995-06-08 |
2023-08-12 |
Not clear |